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Radiation Exposure-Related Interstitial Lung Disease


Presentation

  • Presents more than 120 high-quality images which complement the discussion of specific diseases and provide a clear framework for understanding difficult pulmonary concepts.[books.google.de]
  • He is the editor of five books, has written numerous book chapters and research papers in sarcoidosis and has given presentations at several international scientific meetings.[books.google.de]
  • FIGURE 7: 3-year-old boy with known LIP who presented with worsening respiratory distress.[sajr.org.za]
  • Duration of symptoms – Symptoms that present within days to weeks are seen more so in AIP or COP. Subacute presentations are seen with RBILD and DIP, with the remaining IIPs being chronic in nature. 3.[cancertherapyadvisor.com]
  • This used within the scope of the present invention dosage forms are described in detail in the following part of the description.[google.tl]
Inflammation
  • He is also Principal Investigator in the research group studying “Human Models of Inflammation” at the MRC Centre for Inflammation Research.[books.google.de]
  • Treatment The treatment of ILD depends on the degree of inflammation and scarring.[cumc.columbia.edu]
  • Viruses , bacteria, and fungi can all cause interstitial inflammation.[medicinenet.com]
  • With ILD, the tissue between the air sacs of the lungs (the interstitium) is affected by inflammation or scarring (fibrosis).[uchospitals.edu]
  • Pneumonitis is a general term for inflammation of lung tissue. Chronic inflammation of lung tissue can lead to irreversible scarring (pulmonary fibrosis). Pneumonitis is not a specific disease but a sign of an underlying problem.[patient.info]
Physician
  • He began his training as a junior doctor in London and Oxford where he gained Membership of the Royal College of Physicians.[books.google.de]
  • Physicians don't know the cause of many common types of ILD, including the most common variety known as idiopathic pulmonary fibrosis.[uchospitals.edu]
  • You will subsequently meet with one of our ILD physicians and have a detailed medical history taken and a physical examination performed. Your visit with the ILD physician will last approximately 45 to 60 minutes.[cumc.columbia.edu]
  • Types of Interstitial Lung Disease Our physicians evaluate all forms of this lung condition including: Acute interstitial pneumonia (AIP or Hamman-Rich syndrome) Connective tissue-related lung fibrosis (scleroderma, systemic lupus erythematosis, Sjogren's[hospitals.jefferson.edu]
  • A physician may employ several methods to diagnose Radiation-Induced Pulmonary Fibrosis.[dovemed.com]
Pneumonia
  • Topics include lung cancer screening and staging systems, radiation dose techniques, nodule characterization, PET/CT in the thorax, MDCT and MR evaluation of thoracic aorta, pulmonary emboli and perfusion imaging, interstital pneumonias, emphysema and[books.google.de]
  • […] fibrosis syndrome Hereditary pulmonary alveolar proteinosis House allergic alveolitis Hypersensitivity pneumonitis Idiopathic eosinophilic pneumonia Idiopathic interstitial pneumonia Idiopathic pulmonary fibrosis Idiopathic pulmonary hemosiderosis Infant[se-atlas.de]
  • Assigned diseases: Back to detailed view In the following you will find the diseases that this support group organisation focuses on: 16q24.1 microdeletion syndrome Acute interstitial pneumonia Acute lung injury Acute respiratory coronavirus infection[se-atlas.de]
  • , acute interstitial pneumonia, cryptogenic organizing pneumonia Chronic: Chronic eosinophilic pneumonia, cryptogenic organizing pneumonia, lymphoproliferative disorders, pulmonary alveolar proteinosis , sarcoidosis Linear or reticular opacities Acute[en.wikipedia.org]
  • Cryptogenic organizing pneumonia (COP): A pneumonia-like interstitial lung disease but without an infection present. COP is also called bronchiolitis obliterans with organizing pneumonia (BOOP).[webmd.com]
Hypertension
  • The text provides updated coverage of diagnostic modalities in pulmonary disease, as well as management of asthma, lung cancer, respiratory failure, pulmonary hypertension, and other important pulmonary diseases.[books.google.de]
  • Collagen Vascular Diseases (Pleuropulmonary Manifestations) Rheumatoid Arthritis Pleuritis with or without effusion Necrobiotic nodules Caplan's syndrome (rheumatoid pneumoconiosis) Interstitial pulmonary fibrosis Pulmonary arteritis and pulmonary hypertension[lumen.luc.edu]
  • Pulmonary hypertension occurs when the blood vessels in the alveoli are extremely damaged by scarring. To treat this problem, a patient may receive medicines that will relax or expand the blood vessels.[asbestos.com]
  • Pulmonary hypertension is a form of high blood pressure that affects the arteries within the lungs.[medicinenet.com]
  • […] therapies for ILD include the use of supplemental oxygen, pulmonary rehabilitation, treatment of coexisting pulmonary conditions (such as chronic obstructive pulmonary disease or obstructive sleep apnea) and or complications of ILD (such as pulmonary hypertension[cumc.columbia.edu]
Vascular Disease
  • Diffuse alveolar hemorrhage also associated with systemic vasculitis, progressive glomerulonephritis, collagen vascular disease, and immunocompromised hosts.[lumen.luc.edu]
  • These types of conditions are also considered to be connective tissue diseases, collagen vascular diseases, or rheumatologic diseases which all affect the immune system.[pulmonaryfibrosisnews.com]
  • Tests for collagen vascular disease ( lupus , rheumatoid arthritis ), arterial blood gases, liver tests , and others may be beneficial. Noninvasive tests that measure lung function are known as pulmonary function tests (PFTs).[medicinenet.com]

Workup

  • A proper and detailed history looking for the occupational exposures, and for signs of conditions listed above is the first and probably the most important part of the workup in patients with interstitial lung disease.[en.wikipedia.org]
  • At present, there is no consensus for a definite diagnostic workup approach in patients with a suspicion of diffuse DILD.[benthamopen.com]

Treatment

  • Guides you through the anatomy, physiology, and pathophysiology relevant to major pulmonary disorders, and then focuses on the clinical aspects and treatment of specific diseases.[books.google.de]
  • Treatment The treatment of ILD depends on the degree of inflammation and scarring.[cumc.columbia.edu]
  • The primary goal in the treatment of ILD is to reduce the buildup of scar tissue.[hospitals.jefferson.edu]
  • For some people, adding natural treatments to their current treatment plan has helped. These types of treatments can include dietary supplements, herbs, gentle exercise and cellular therapy.[lunginstitute.com]

Prognosis

  • Prognosis. In the case of pneumonitis with a good response to treatment, the prognosis is favorable. The prognosis for fibrosis is variable.[archbronconeumol.org]
  • (Outcomes/Resolutions) Prognosis of Radiation-Induced Pulmonary Fibrosis depends upon the extent of scarring in the lungs and resulting symptoms.[dovemed.com]
  • Prognosis Prognosis is good with early diagnosis and management. Late-diagnosed chronic pneumonitis may lead to progressive, irreversible lung disease.[patient.info]
  • For discussion of these features please refer to: radiation pneumonitis radiation fibrosis Treatment and prognosis Steroid can reduce the severity of acute radiation pneumonitis 1 .[radiopaedia.org]

Etiology

  • Immune modulators and corticosteroids are used in cases of unknown etiology. In advanced stages of disease ILD can result in pulmonary insufficiency and respiratory heart failure with right ventricular insufficiency.[amboss.com]
  • While there are multiple methods by which to classify these diseases, one option is to classify by their etiologies. There are seven categories that are frequently used: 1.[cancertherapyadvisor.com]
  • Bronchiolitis obliterans of unknown etiology Bronchiolitis Obliterans and Organizing Pneumonia Also known as BOOP. Steroids effective.[lumen.luc.edu]
  • This article provides an up-to-date review on etiology, imaging findings and management of pulmonary HIV infection in infants and children.[sajr.org.za]
  • Etiology Xu D, Chen Z, Chen H, Huang R, Zhao S, Liu X, Zhou C, Peng Y, Yuan X, Zou J, Zhang H, Zhao D, Liu E, Zheng Y, Zhong L, Lu M, Lu J, Nong G PLoS One 2015;10(1):e0116930. Epub 2015 Jan 8 doi: 10.1371/journal.pone.0116930.[ncbi.nlm.nih.gov]

Epidemiology

  • Based on the Bernalillo County, NM, USA registry data published in 1994, the overall estimated incidence is approximately 30 cases per 100,000 persons per year. [2] Rates of interstitial lung disease are somewhat higher in men than in women, and the epidemiology[emedicine.medscape.com]
  • Epidemiology It is common, if all causes of pneumonitis are considered.[patient.info]
  • For nonmalignant respiratory diseases, animal studies provided some relevant findings, and a few epidemiologic studies had been reported.[nap.edu]
  • The epidemiology of interstitial lung diseases. Am J Respir Crit Care Med . 1994;150:967-972. 7. Thomeer M, Costabel U, Rizzato G, et al. Comparison of registries of interstitial lung diseases in three European countries.[pharmacytimes.com]
  • In light of these criticisms, this Committee reviewed the latest epidemiologic data on lung cancer in underground uranium miners employed in Colorado and New Mexico.[ehss.energy.gov]
Sex distribution
Age distribution

Pathophysiology

  • Guides you through the anatomy, physiology, and pathophysiology relevant to major pulmonary disorders, and then focuses on the clinical aspects and treatment of specific diseases.[books.google.de]
  • Furthermore, we know two other pathophysiologic principles in pulmonary toxicity [ 75 Kaarteenaho R, Kinnula V. Diffuse alveolar damage: A common phenomenon in progressive interstitial lung disorders Pulm Med 2011; 2011: 531302. ].[benthamopen.com]

Prevention

  • Prevention Since the late 1970s, many regulations have been enacted to protect workers from asbestos exposure. Reducing or eliminating asbestos exposure is the best way to prevent asbestosis.[asbestos.com]
  • Can interstitial lung disease be prevented? Interstitial lung disease can be prevented only to the extent that its individual causes may be prevented.[medicinenet.com]
  • Alternatively, medications have been tried in an attempt to prevent the development of lung injury.[clinicaladvisor.com]

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