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Radiation Pericarditis


Presentation

  • Presents full-color images throughout to match the images that you see in practice. Extensive use of "combination" imaging presents a complete picture of how to more precisely locate and target the radiotherapy field.[books.google.com]
  • Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.[books.google.com]
  • Surgical treatment frequently uncovers an underlying restrictive myopathy that presents a serious diagnostic and therapeutic challenge.[ncbi.nlm.nih.gov]
  • He has been editor in chief of the Iranian journal Reports in Radiation Oncology since 2013, and his present research focus is radiation therapy complications in patients with head and neck malignancies.[books.google.com]
Ankle Edema
  • This includes a pericardial knock Pericardial rub (heard best while leaning forwards) and distant heart sounds Abdomen Hepatomegaly Ascites Extremities Ankle edema Electrocardiogram Non-specific ST and T wave changes or ST segment elevation in all leads[wikidoc.org]
Regurgitation
  • All patients had mitral regurgitation, 5 had also tricuspid insufficiency and 5 had aortic regurgitation. The degree of the valvular regurgitation was or 3 in four instances. Critical coronary arterial stenoses were discovered in 3 cases.[ncbi.nlm.nih.gov]
  • Prevention of excessive dilation of heart especially during sudden rise in intracardiac volume e.g. acute aortic or mitral regurgitation. Intrapericardial pressure (IPP) tracks intrathoracic pressure.[brown.edu]
  • Thus, patients with pericarditis may be thought to have aortic stenosis, mitral regurgitation, or ventricular septal defect.[tele.med.ru]
Chest Pain
  • I hope your doctor is able to find a way to resolve your breathing and chest pain issues. I know it is uncomfortable (to say the least), and worrisome for you. Once again, welcome to DC! Kathy[drugs.com]
  • pain that improves on leaning forward and worsens on inspiration Breathlessness Dizziness Palpitation Malaise Ankle edema Physical Examination Patients may present with fever Vitals Pulse Rate Tachycardia Blood Pressure Hypotension Neck Jugular venous[wikidoc.org]
  • Of note, the patient states that after the surgery, he had resolution of his chest pain, but he has started experiencing chest pain again.[medbullets.com]
  • Inflammation of this membrane may cause chest pain.[chemocare.com]
Pericardial Friction Rub
  • Signs The typical auscultory finding of pericarditis is the "Pericardial Friction Rub" which is observed as a high-pitched, scratching sound likely caused by the inflamed pericardial layers rubbing against one another.[pathwaymedicine.org]
  • This loud precordial sound, the result of air in the mediastinum, may be confused with a pericardial friction rub.[tele.med.ru]
  • The most common physical finding that helps confirm the diagnosis of pericarditis is a pericardial friction rub. Inflammation prevents the two layers of pericardium from easily sliding against each other with each heartbeat.[medicinenet.com]
  • Pericardial friction rub is best heard in the supine position at the end of exhalation. Hepatojugular reflux may be observed. Fluid (and hence signs) usually develop slowly with cardiac tamponade developing late as a complication.[patient.info]
  • A pericardial friction rub, caused by a swollen pericardium coming into contact with the chest wall, may be heard.[calshipleymd.com]
Cutaneous Manifestation
  • Manifestations of Cancer 2349 Colon Cancer 240 2352 Approach to the Patient with Paraneoplastic Neurologic Disease 2359 Gastrointestinal Cancers 664 2376 HepaticoBiliary System 713 2381 Summary 668 2384 Diagnosis 1237 2389 Treatment 2396 HOWLEY DON GANEM[books.google.com]
Excitement
  • This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer.[books.google.com]

Workup

  • 1859 Infectious Agents and Cancer 549 1860 Cancer of the Skin 1863 Melanoma 1889 Diagnostic Studies and Pretreatment Staging 1001 1908 Principles of Isolation Perfusion 701 1923 Intraocular Melanomas 1951 Invasion and Metastasis 117 1952 Metastatic WorkUp[books.google.com]
Pericardial Effusion
  • Abstract We report surgical management of radiation-induced massive pericardial effusion.[jstage.jst.go.jp]
  • Right now, because I have another case of pericardial effusion, my cardio and PCP have been checking into the possibility of an autoimmune disease causing it. But, I believe it was caused by my chemo.[drugs.com]
  • Pericardiocentesis Radiation induced pericardial effusion can be confused with malignant pericarditis and hypothyroidism (secondary to mediastinal irradiation) induced pericarditis.[wikidoc.org]
  • Causes There are many causes of pericardial effusions.[verywell.com]
  • Pericardial effusion and tamponade. Pericarditis usually is accompanied by pericardial effusion.[tele.med.ru]
Helicobacter Pylori
  • Pylori 554 2100 Principles of the World Health Organization Classification of Lymphoid Neoplasms 2106 Specific Disease Entities 2115 Special Clinical Situations 2136 Cutaneous TCell Lymphomas 2143 Principles of Therapy of Mycosis Fungoides and the Sézary[books.google.com]
Hepatocellular Carcinoma
  • Carcinoma 1139 1644 Cancer of the Endocrine System 1655 Thyroid Tumors 1663 Parathyroid Cancer 1682 Adrenal Tumors 1690 Pheochromocytomas 1697 Von HippelLindau 1315 1698 Genetic and Environmental Risk Factors 1233 1700 Tumor Classification Histopathology[books.google.com]

Treatment

  • Left thoracotomy is an effective alternative to median sternotomy for the surgical treatment of radiation pericarditis, with a mild increase in pulmonary-associated complications.[ncbi.nlm.nih.gov]
  • The clinical consequences of this finding with respect to surgical treatment are briefly discussed.[ncbi.nlm.nih.gov]
  • Progressing from fundamental principles through specific treatment strategies for the cancers of each organ system, it also addresses the effects of radiation on normal structures and the avoidance of complications.[books.google.com]
  • Image source: imagina / MorgueFile.com I was contacted this week by one of my Facebook fans, a lady who is 44, normally in good health, but currently undergoing radiation treatments for breast cancer.[marnieclark.com]
  • Classification Histopathology and Molecular Genetics 1703 Cholangiocarcinomas 1157 1712 Natural History and Patterns of Failure 1000 1713 Emerging Therapeutic Options 1718 Incidence 1186 1720 Clinical Presentation 1001 1723 Anatomy of the Colon 1236 1724 Treatment[books.google.com]

Prognosis

  • Prognosis The prognosis of a pericardial effusion depends largely on the cause. With infections, inflammatory disease, or kidney disease that can be managed, the prognosis may be very good.[verywell.com]
  • Prognosis is strongly linked to the underlying cause but long-term survival is more likely with surgery and the best results are achieved if surgery is offered early.[patient.info]
  • What Is the Average Prognosis? The common prognosis for the pericardial type is poor, compared to that of peritoneal or pleural mesothelioma. Nearly 50 to 60 percent of pericardial patients pass away within six months of receiving a diagnosis.[asbestos.com]
  • Etiology, treatment, and prognosis of large pericardial effusions. Chest 1991;100:985–987. Excellent clinical review of 34 patients presenting with large pericardial effusions. Ling LH, Oh JE, Breen JF, et al.[tele.med.ru]

Etiology

  • "Constrictive pericarditis: etiology and cause-specific survival after pericardiectomy". J Am Coll Cardiol. 43 (8): 1445–52. doi : 10.1016/j.jacc.2003.11.048. PMID 15093882.[wikidoc.org]
  • Overview Pericarditis can be caused by both infectious and noninfectious etiologies.[pathwaymedicine.org]
  • Other tests are performed based on clinical suspicion of a specific etiology or to exclude certain etiologies.[brown.edu]
  • Here we present a rare case of constrictive pericarditis of possible tuberculous etiology and review the diagnosis and management of the condition.[alliedacademies.org]
  • If the etiology of the pericarditis is clear and if signs of tamponade are not present, pericardiocentesis or pericardial biopsy is not required.[tele.med.ru]

Epidemiology

  • Carcinoma of the Vulva 1528 Cancer of the Uterine Body 1543 Chemoprevention 609 1545 Uterine Sarcomas 1557 Gestational Trophoblastic Diseases 1564 Colon Cancer 1232 1574 Epothilones 455 1586 Genetic Predisposition 1390 1595 Epidemiology 1232 1604 Malignant[books.google.com]
  • Epidemiology and Demographics Incidence of radiation induced pericarditis has significantly decreased with the use of lower doses and newer radiotherapy techniques [3] [4].[wikidoc.org]
  • Epidemiology of mesothelioma of the pericardium and tunica vaginalis testis. Annals of Epidemiology, 27(5):348-359. doi: 10.1016/j.annepidem.2017.04.001 Nambiar, C. et al. (1992). Primary pericardial mesothelioma: One-year event-free survival.[asbestos.com]
  • Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology[brainscape.com]
  • "As the epidemiological studies do not give clues on the important mechanisms underlying RIHD, it is difficult to design preventive strategies.[medicalphysicsweb.org]
Sex distribution
Age distribution

Pathophysiology

  • It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care.[books.google.com]
  • Pathophysiology Radiation exposure causes endothelial damage, capillary rupture, and platelet adhesion which initiates an inflammatory response and leads to development of adhesions between the two membranes of pericardium.[wikidoc.org]
  • The pathophysiology remains poorly understood, but radiation "might harm virtually all cardiac tissues and the underlying pathophysiological mechanisms may be related to micro- and macrovascular damages," they explained.[medicalphysicsweb.org]
  • Pathophysiology and Classification Depending on the underlying cause, the acute inflammatory response in pericarditis may produce serous fluid, pus, or dense fibrinous material.[aafp.org]
  • Pathophysiology of the Pericardium. Progress in cardiovascular diseases. 2016. Tse G, Ali A, Alpendurada F, et al. Tuberculous Constrictive Pericarditis. Res Cardiovasc Med. 2015;4:e29614. Syed FF, Mayosi BM.[alliedacademies.org]

Prevention

  • Clear back in the 1960s, it became known that, after receiving adjuvant radiation to prevent breast cancer recurrence, quite a few women were dying of heart disease, often decades after their breast cancer diagnosis (Fajardo 2001).[marnieclark.com]
  • The scarring constricts the movement of the heart during each heartbeat and can prevent the heart from expanding to accept blood returning from the body after each heartbeat.[medicinenet.com]
  • This tissue helps to anchor the heart in place, prevents excessive movement of the heart in the chest when body position changes, protects the heart from infections and tumors that develop in and may spread from nearby tissues, and may help keep the heart[healthcommunities.com]
  • This can prevent your heart chambers from filling up with the right amount of blood, leading to the symptoms of heart failure. The cause of constrictive pericarditis isn’t always known.[healthline.com]
  • "As the epidemiological studies do not give clues on the important mechanisms underlying RIHD, it is difficult to design preventive strategies.[medicalphysicsweb.org]

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