The literature is reviewed and a case is reported in which a patient presented with a significant increase in caries rate attributed to salivary dysfunction following radioactive iodine therapy for a thyroid carcinoma. [ncbi.nlm.nih.gov]

Download Figure Figure 2 Takotsubo cardiomyopathy on echocardiogram – parasternal long axis on original presentation. [edm.bioscientifica.com]

• Pain

  In April 1944 and March 1945 additional I* was administered with a resultant disappearance of pain, increase in weight, and progressive change in all clinical criteria in the direction of hypothyroidism. [ncbi.nlm.nih.gov]

  Although serious complications are uncommon after treatment, there are well-documented adverse reactions secondary to the involvement of the salivary glands, such as dry mouth, pain in the parotid glands and dysphagia, even after administration of low [clinicaltrials.gov]

• Thyroid Nodule

  Frates MC et al. (2005) Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statement—thyroid nodule shape and prediction of malignancy. Radiology 237 : 794–800 4. [nature.com]

  BACKGROUND: A 55-year-old male was diagnosed with poorly differentiated thyroid cancer after total thyroidectomy, which was performed because of progressive enlargement of a dominant thyroid nodule. [ncbi.nlm.nih.gov]

  Why It Is Done Radioactive iodine may be used to treat hyperthyroidism in people who have noncancerous (benign) thyroid nodules that make too much thyroid hormone. [northshore.org]

  One could speculate that if the 131 I is only taken up in the hyperfunctioning nodules, the reduction in the thyroid volume would be based on the changes in these nodules, leaving the paranodular tissue unaffected with a potential of growth. [jamanetwork.com]

• Inflammation

  You can have painkillers to help with the inflammation. To reduce the risk of getting this side effect, it can help to drink plenty of fluids during your hospital stay. [cancerresearchuk.org]

  dry mouth, general swelling and inflammation of the mouth as well as taste and smell having short term issues. [large.stanford.edu]

  Complications commonly seen following larger doses of RAI used in thyroid cancer include nausea, radiation induced thyroid gland inflammation, radiation induced inflammation of salivary glands, painless neck swelling, and tumor hemorrhage. [gdatf.org]

  Thyroid crisis (due to the release of large amounts of thyroid hormone), severe inflammation of the salivary glands, and chromosomal abnormalities may occur. [medicinenet.com]

  As radioactive iodine can induce considerable inflammation in the thyroid, this leads to leakage of thyroid hormone from the damaged thyroid into the blood. [mythyroid.com]

• Fatigue

  RESULTS: Sudoresis was the most frequent side effect of pilocarpine use, followed by fatigue and headache. Two patients reported relief of xerostomia using pilocarpine, but only one patient was able to tolerate the side effects. [ncbi.nlm.nih.gov]

  However, most chemotherapy drugs affect other rapidly-dividing cells in the body that aren't cancerous, leading to a number of side effects, including hair loss, diarrhea, and fatigue. [everydayhealth.com]

  These may include: difficulty concentrating, fatigue, blue or sad mood, puffiness around the eyes, dry skin, water retention, weight gain, constipation and fatigue. [oncolink.org]

  Fatigue. Unusually low ( hypothyroidism ) or unusually high ( hyperthyroidism ) thyroid levels. What To Think About If you are pregnant, you should not receive radioactive iodine treatment. [northshore.org]

• Falling

  Further, the dose rate falls off rapidly with distance; those farther from you receive less radiation exposure. The dose rate also falls off rapidly with time because 131 I doesn't remain in the body very long. [hps.org]

  […] and Falls Injury Prevention Program Social Work – Aged Care Inpatient Services Transitional Therapy and Care Program Alcohol and Drug Services Our Services Consultation Liaison Services Counselling and treatment service Diversion services Needle and [health.act.gov.au]

  Earle Chapman, a clinician on the voluntary staff of the MGH, took over Hertz's practice in 1943; their later differences over the precise treatment and who was in charge led to their falling out. [ncbi.nlm.nih.gov]

  It falls under the category of an anti- thyroid drug but differs from the other anti-thyroid drugs, propylthiouracil (PTU) and methimazole ( Tapazole ), because it is radioactive. [medicinenet.com]

  After radiation-induced hypothyroidism develops, it takes only 6 weeks without thyroid replacement hormone for patients to fall into myxedema coma. Increased antibody titers after RAI skew lab test results, adding to treatment difficulties. [stopthethyroidmadness.com]

• Dyspnea

  He developed recent symptoms of dyspnea, dysphagia, neck welling and uniintentional weight loss. Computed tomography of the neck was done revealing a large MNG with retrosternal extension and calcifications. [ncbi.nlm.nih.gov]

  Four days after radioiodine administration, she presented to the emergency department with chest tightness and dyspnea due to heart failure. Biochemistry revealed thyrotoxicosis and significantly elevated Troponin-T. [edm.bioscientifica.com]

• Hoarseness

  Thyroid cancer surgery may cause the following side effects: Temporary or permanent voice hoarseness Low blood calcium levels (from damage to the nearby parathyroid glands) Excessive bleeding, blood clots, or wound infections Also, after undergoing a [everydayhealth.com]

• Dysphagia

  He developed recent symptoms of dyspnea, dysphagia, neck welling and uniintentional weight loss. Computed tomography of the neck was done revealing a large MNG with retrosternal extension and calcifications. [ncbi.nlm.nih.gov]

  Although serious complications are uncommon after treatment, there are well-documented adverse reactions secondary to the involvement of the salivary glands, such as dry mouth, pain in the parotid glands and dysphagia, even after administration of low [clinicaltrials.gov]

• Xerostomia

  Two patients reported relief of xerostomia using pilocarpine, but only one patient was able to tolerate the side effects. [ncbi.nlm.nih.gov]

  Symptomatic complaints at the time of sialendoscopy included pain and swelling of the parotid or submandibular gland, xerostomia, and exacerbation of symptoms with eating. [jamanetwork.com]

  Thyroid. 2003 Mar;13(3):265-71. and Salivary Gland Function Five Years after a Radioiodine Ablation in Patients with Differentiated Thyroid Cancer: Direct Comparison of Pre and Post-Ablation Scintigraphies and Their Relation to Xerostomia Symptoms. [mythyroid.com]

• Fussiness

  Resources Breastfeeding Looking after your mental health Genetic Counselling Maternal and Child Health (MACH) MACH Health Checks Children and Youth Community Paediatric and Child Health Children’s Asthma Education Service (CAES) Hearing Eye Screening Fussy [health.act.gov.au]

• Amenorrhea

  Effects on gonadal function resulting in transient low sperm concentration, decreased ovarian function, and amenorrhea can occur following higher doses of RAI used in thyroid cancer. [gdatf.org]

  […] gastrointestinal symptoms like nausea and vomiting due to radiation gastritis, transient bone marrow depression (anemia in 36% of the patients, leukopenia 10%, thrombocytopenia 3%), radiation pneumonitis and pulmonary fibrosis, radiation cystitis, transient amenorrhea [intechopen.com]

  Amenorrhea due to temporary ovarian dysfunction (18,19) and depression of spermatogenesis (20) after radioiodine treatment have been observed. Spontaneous abortion rates range from 15 to 20%. [scielo.br]

• Hyperactivity

  RAI scanning can help determine if the entire gland is hyperactive (usually seen in Graves' disease) or if only specific nodules are hyperactive (i.e. toxic adenoma). [columbiasurgery.org]

  Radioactive iodine is used in diagnostic tests as well as in radiotherapy of an hyperactive thyroid gland ( hyperthyroidism ), most often due to Graves' disease. [medicinenet.com]

  Share this post Link to post Share on other sites I had been on the Carbimazole (hyperactive treatment)for about 5 years when I finally got pregnant. Had twins with no ill effects. [toytowngermany.com]

  As a consequence of the oversupply of thyroid hormone in hyperthyroidism, there is hyperactivity of the central nervous system manifested by nervousness, irritability, restlessness and hyperactivity, increased heart rate and force of heart contraction [gdatf.org]

• Difficulty Concentrating

  These may include: difficulty concentrating, fatigue, blue or sad mood, puffiness around the eyes, dry skin, water retention, weight gain, constipation and fatigue. [oncolink.org]

• Agitation

  Beta-blockers (propranolol, Inderal, Inderal LA, InnoPran XL) This medicine can help block the body's reaction to hyperthyroidism It can control heart-related symptoms, such as palpitations, tremors, and agitation Iodide solutions (Lugol's solution, Strong [emedicinehealth.com]

Ten days later, laboratory workup was: TSH: 0.01 uIU/ml; FT4: >7.77 ng/dl. He was kept in use of propranolol 80 mg tid and methimazole (MMI) 40 mg q.d. was initiated. [casesjournal.biomedcentral.com]

Graves disease management Graves disease complicated by a nodular thyroid gland unresponsive to usual medical therapy or in older adults Consultation with an ophthalmologist may be needed in the following situations: Unilateral or bilateral proptosis Workup [emedicine.medscape.com]

• Thyroid-Stimulating Hormone Increased

  This depletes the body’s levels of inorganic iodine, a mineral the thyroid uses to make thyroid hormone. When iodine levels are low, thyroid-stimulating hormone signals the thyroid cells to increase thyroid hormone production. [nyulangone.org]

RECENT FINDINGS: Since the 1940s radioactive (131)I (RAI) therapy has been a major component of the treatment of hyperthyroidism and differentiated thyroid cancer. RAI is the most common definitive treatment of hyperthyroidism. [ncbi.nlm.nih.gov]

Kaplan-Meier PFS and OS curves showed that age on diagnosis, tumor histology, tumor size, DTC aggressive variant, and Tg-on were associated with prognosis. [ncbi.nlm.nih.gov]

This is a reflection of their uncertainties regarding their prognosis as these patients had more extensive disease. They were also older than patients with regular menstruation and many had already had their children. [pmj.bmj.com]

Three or more consecutive abortions are called recurrent and warrant investigation for etiologic factors, namely genetic, hormonal, immunological or other factors (21,22). [scielo.br]

[…] management Graves disease complicated by a nodular thyroid gland unresponsive to usual medical therapy or in older adults Consultation with an ophthalmologist may be needed in the following situations: Unilateral or bilateral proptosis Workup of other etiologies [emedicine.medscape.com]

METHODS: This was a retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) database, 2004-2012. RESULTS: A total of 38,374 patients with PTC were identified. Of those, 56.3% had adjuvant RAI. [ncbi.nlm.nih.gov]

[…] within the first two years of treatment with radioactive iodine In Cleveland Clinic’s investigation, summarized in the abstract Radioactive Iodine Treatment of Thyroid Cancer and Risk of Myelodysplastic Syndromes, researchers examined 18 Surveillance Epidemiology [consultqd.clevelandclinic.org]

[…] children and young people It’s Your Move Create-a-café Entrepreneurs: It’s Your Move Curriculum Girls: It's Your Move High school resources It’s Your Move schools Research pilot P.A.R.T.Y. program Make a P.A.R.T.Y. booking PARTY Expression of Interest 2019 Epidemiology [health.act.gov.au]

Issues and epidemiological evidence regarding radiation-induced thyroid cancer. Radiat Res. 1992;131:98-111. Google Scholar 39. Ron E, Lubin JH, Shore RE. et al. [jama.ama-assn.org]

The pathophysiology of this relationship has yet to be completely elucidated, but elevated levels of thyroxine in the aqueous humor and tear film and thyroxine receptors in the cornea likely play a role. [ncbi.nlm.nih.gov]

Based upon many reports of rising TSH receptor antibody titers after 131 I as important to underlying pathophysiology, and upon the weight of randomised prospective studies (REF 110, 120, 121) there exists some basis to believe that Graves’ Ophthalmopathy [stopthethyroidmadness.com]

Psychiatric manifestations of Graves' hyperthyroidism: pathophysiology and treatment options. CNS Drugs. 2006. 20(11):897-909. [Medline]. Vogel A, Elberling TV, Hørding M, Dock J, Rasmussen AK, Feldt-Rasmussen U. [emedicine.medscape.com]

The most important reason to use glucocorticoids concomitantly with RAI administration is to prevent the possible RAI-associated worsening of Graves’ ophthalmopathy (GO). [eje.bioscientifica.com]

Accreditation Infection Prevention and Control The Office for Mental Health and Wellbeing Vision and Priority Workshops Frequently Asked Questions LifeSpan - Integrated Suicide Prevention Primary navigation Page last updated on: 7 Jan 2019 [health.act.gov.au]

Because an amelioration of salivary gland function was observed in the present study, our results suggest the efficacy of aromatherapy in the prevention of treatment-related salivary gland disorder. [ncbi.nlm.nih.gov]

Best Practices Use antithyroid agents with or without beta-blockers before treatment with sodium iodide I 131 to prevent symptomatic radiation thyroiditis. [emedicine.medscape.com]