The literature is reviewed and a case is reported in which a patient presented with a significant increase in caries rate attributed to salivary dysfunction following radioactive iodine therapy for a thyroid carcinoma. [ncbi.nlm.nih.gov]

Download Figure Figure 2 Takotsubo cardiomyopathy on echocardiogram – parasternal long axis on original presentation. [edm.bioscientifica.com]

• Inflammation

  You can have painkillers to help with the inflammation. To reduce the risk of getting this side effect, it can help to drink plenty of fluids during your hospital stay. [cancerresearchuk.org]

  dry mouth, general swelling and inflammation of the mouth as well as taste and smell having short term issues. [large.stanford.edu]

  Complications commonly seen following larger doses of RAI used in thyroid cancer include nausea, radiation induced thyroid gland inflammation, radiation induced inflammation of salivary glands, painless neck swelling, and tumor hemorrhage. [gdatf.org]

  Thyroid crisis (due to the release of large amounts of thyroid hormone), severe inflammation of the salivary glands, and chromosomal abnormalities may occur. [medicinenet.com]

  As radioactive iodine can induce considerable inflammation in the thyroid, this leads to leakage of thyroid hormone from the damaged thyroid into the blood. [mythyroid.com]

• Myxedema

  With hypothyroidism one is at risk of myxedema coma which can be more deadly than thyroid storm. This results from improper monitoring and labs tests, keeping us in a hypO state. [stopthethyroidmadness.com]

  Some degree of pretibial (localized dermopathy) myxedema is observed in 5-10% of patients, with 1-2% having cosmetically significant lesions. [emedicine.medscape.com]

  I have had a thyroid issue since puberty and at the point where I was told I needed this test, they were thinking I had something called ''myxedema madness'' - a psychosis related to underactive thyroid. [toytowngermany.com]

• Dysphagia

  He developed recent symptoms of dyspnea, dysphagia, neck welling and uniintentional weight loss. Computed tomography of the neck was done revealing a large MNG with retrosternal extension and calcifications. [ncbi.nlm.nih.gov]

  Although serious complications are uncommon after treatment, there are well-documented adverse reactions secondary to the involvement of the salivary glands, such as dry mouth, pain in the parotid glands and dysphagia, even after administration of low [clinicaltrials.gov]

• Fear

  It has been on the basis of these fears that some physicians have given antithyroid drugs or iodide to patients soon after their therapeutic dose of radioactive iodine. [academic.oup.com]

  Note: Don't let your fears about radiation give you the wrong impression about this therapy. Radioactive iodine used in this manner will not cause thyroid cancer or impair fertility. [endocrineweb.com]

  In conclusion, in patients in whom it is required (smokers with preexisting GO, severe hyperthyroidism, high TRAb titers), glucocorticoid therapy can be safely administered without any fear of compromising the outcome of RAI therapy. [eje.bioscientifica.com]

  In many countries, including Australia, patients are reluctant to be treated with radioactive iodine initially because of fear of radiation and most endocrinologists accept this and do not try to convince their patients otherwise. [hoajonline.com]

• Amenorrhea

  Effects on gonadal function resulting in transient low sperm concentration, decreased ovarian function, and amenorrhea can occur following higher doses of RAI used in thyroid cancer. [gdatf.org]

  […] gastrointestinal symptoms like nausea and vomiting due to radiation gastritis, transient bone marrow depression (anemia in 36% of the patients, leukopenia 10%, thrombocytopenia 3%), radiation pneumonitis and pulmonary fibrosis, radiation cystitis, transient amenorrhea [intechopen.com]

  Amenorrhea due to temporary ovarian dysfunction (18,19) and depression of spermatogenesis (20) after radioiodine treatment have been observed. Spontaneous abortion rates range from 15 to 20%. [scielo.br]

• Hyperactivity

  RAI scanning can help determine if the entire gland is hyperactive (usually seen in Graves' disease) or if only specific nodules are hyperactive (i.e. toxic adenoma). [columbiasurgery.org]

  Radioactive iodine is used in diagnostic tests as well as in radiotherapy of an hyperactive thyroid gland ( hyperthyroidism ), most often due to Graves' disease. [medicinenet.com]

  Share this post Link to post Share on other sites I had been on the Carbimazole (hyperactive treatment)for about 5 years when I finally got pregnant. Had twins with no ill effects. [toytowngermany.com]

  As a consequence of the oversupply of thyroid hormone in hyperthyroidism, there is hyperactivity of the central nervous system manifested by nervousness, irritability, restlessness and hyperactivity, increased heart rate and force of heart contraction [gdatf.org]

• Confusion

  This is to avoid any confusion that may be caused by sensitive radiation recording devices at airports and ferry terminals. [thyroid-cancer-forum-uk.org]

  131-iodine (131I or I-131) is the radioactive isotope used to kill both normal and cancerous thyroid cells This is not to be confused with I-123, a harmless isotope used by radiologists in imaging and to determine thyroid activity Radioactive iodine is [emedicinehealth.com]

  Literature on the association between the aetiology of hyperthyroidism and the outcome is even more confusing. [bjmp.org]

Ten days later, laboratory workup was: TSH: 0.01 uIU/ml; FT4: >7.77 ng/dl. He was kept in use of propranolol 80 mg tid and methimazole (MMI) 40 mg q.d. was initiated. [casesjournal.biomedcentral.com]

Graves disease management Graves disease complicated by a nodular thyroid gland unresponsive to usual medical therapy or in older adults Consultation with an ophthalmologist may be needed in the following situations: Unilateral or bilateral proptosis Workup [emedicine.medscape.com]

• Thyroid Stimulating Hormone Increased

  This depletes the body’s levels of inorganic iodine, a mineral the thyroid uses to make thyroid hormone. When iodine levels are low, thyroid-stimulating hormone signals the thyroid cells to increase thyroid hormone production. [nyulangone.org]

RECENT FINDINGS: Since the 1940s radioactive (131)I (RAI) therapy has been a major component of the treatment of hyperthyroidism and differentiated thyroid cancer. RAI is the most common definitive treatment of hyperthyroidism. [ncbi.nlm.nih.gov]

Kaplan-Meier PFS and OS curves showed that age on diagnosis, tumor histology, tumor size, DTC aggressive variant, and Tg-on were associated with prognosis. [ncbi.nlm.nih.gov]

This is a reflection of their uncertainties regarding their prognosis as these patients had more extensive disease. They were also older than patients with regular menstruation and many had already had their children. [pmj.bmj.com]

Three or more consecutive abortions are called recurrent and warrant investigation for etiologic factors, namely genetic, hormonal, immunological or other factors (21,22). [scielo.br]

[…] management Graves disease complicated by a nodular thyroid gland unresponsive to usual medical therapy or in older adults Consultation with an ophthalmologist may be needed in the following situations: Unilateral or bilateral proptosis Workup of other etiologies [emedicine.medscape.com]

METHODS: This was a retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) database, 2004-2012. RESULTS: A total of 38,374 patients with PTC were identified. Of those, 56.3% had adjuvant RAI. [ncbi.nlm.nih.gov]

[…] within the first two years of treatment with radioactive iodine In Cleveland Clinic’s investigation, summarized in the abstract Radioactive Iodine Treatment of Thyroid Cancer and Risk of Myelodysplastic Syndromes, researchers examined 18 Surveillance Epidemiology [consultqd.clevelandclinic.org]

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Issues and epidemiological evidence regarding radiation-induced thyroid cancer. Radiat Res. 1992;131:98-111. Google Scholar 39. Ron E, Lubin JH, Shore RE. et al. [jama.ama-assn.org]

The pathophysiology of this relationship has yet to be completely elucidated, but elevated levels of thyroxine in the aqueous humor and tear film and thyroxine receptors in the cornea likely play a role. [ncbi.nlm.nih.gov]

Based upon many reports of rising TSH receptor antibody titers after 131 I as important to underlying pathophysiology, and upon the weight of randomised prospective studies (REF 110, 120, 121) there exists some basis to believe that Graves’ Ophthalmopathy [stopthethyroidmadness.com]

Psychiatric manifestations of Graves' hyperthyroidism: pathophysiology and treatment options. CNS Drugs. 2006. 20(11):897-909. [Medline]. Vogel A, Elberling TV, Hørding M, Dock J, Rasmussen AK, Feldt-Rasmussen U. [emedicine.medscape.com]

The most important reason to use glucocorticoids concomitantly with RAI administration is to prevent the possible RAI-associated worsening of Graves’ ophthalmopathy (GO). [eje.bioscientifica.com]

Accreditation Infection Prevention and Control The Office for Mental Health and Wellbeing Vision and Priority Workshops Frequently Asked Questions LifeSpan - Integrated Suicide Prevention Primary navigation Page last updated on: 7 Jan 2019 [health.act.gov.au]

Because an amelioration of salivary gland function was observed in the present study, our results suggest the efficacy of aromatherapy in the prevention of treatment-related salivary gland disorder. [ncbi.nlm.nih.gov]

Best Practices Use antithyroid agents with or without beta-blockers before treatment with sodium iodide I 131 to prevent symptomatic radiation thyroiditis. [emedicine.medscape.com]