We report the case of a 75-year-old woman, presenting to the emergency department with acute renal failure and electrolyte imbalance, reporting an history of recurrent episodes of dehydration and chronic diarrhea. [ncbi.nlm.nih.gov]

Case presentation: In this case we describe a 28-year-old female patient suffering from 6 months of secretory diarrhea, presented to our emergency department with severe dehydration, acute renal failure, hyponatremia and hypokalemia. [imedpub.com]

Carcinoma present at or within 1 mm of the surgical margin Usually recognized by cautery Measure from the superficial edge of the cautery where tissue is still recognizable High grade carcinoma (see Grading at left), even if only focal in the lesion [surgpathcriteria.stanford.edu]

We present a case of an 87 year old man presented to the emergency department because of an incarcerated rectal prolapse totally carpeted by a giant villous rectal adenoma. [tropicalgastro.com]

• Rectal Bleeding

  Case Report A 58-year-old woman without previous major diseases starts suffering from evacuatory straining, occasional rectal bleeding and mass sensation 1 year prior to attending to a local ambulatory center. [omicsonline.org]

  They also may be involved in abnormal secretory activity associated with diarrhea and electrolyte imbalance, rectal bleeding or obstruction [2, 3 ]. [tropicalgastro.com]

  bleeding correlates with size and may be seen in as many as 67% • Imaging • Rate of detection of polyps less than 1 cm is higher with air contrast • Rate of detection of polyps 1cm or greater is about equal with single vs. double contrast • From 1/4 [learningradiology.com]

  This is the case of an octogenarian man with a several year history of hemorrhoids and intermittent rectal bleeding, more recently complaining of continuous hematochezia. [wjgnet.com]

  Rectal bleeding is usually intermittent, with a small amount of dark blood mixed with the stool. A palpable mass in the left side of the abdomen. [surgwiki.com]

• Chronic Diarrhea

  We report the case of a 75-year-old woman, presenting to the emergency department with acute renal failure and electrolyte imbalance, reporting an history of recurrent episodes of dehydration and chronic diarrhea. [ncbi.nlm.nih.gov]

  It has been suggested that the triad of prerenal failure, electrolyte disorder and chronic diarrhea should always prompt a complete colonoscopy [ 4 ]. [bmcsurg.biomedcentral.com]

  Diarrhea and Acute Renal Failure. [imedpub.com]

• Rectal Mass

  Eight months later, she attends to the emergency department of the Hospital Universitario de Caracas with abdominal pain, growth of the rectal mass, rectal bleeding, and proctalgia so she is evaluated by the gastroenterology department and later referred [omicsonline.org]

  Transanal endoscopic microsurgery is more effective than traditional transanal excision for resection of rectal masses. Dis Colon Rectum. 2008; 51 :1026–1030; discussion 1030-1031. [ PubMed ] [ Google Scholar ] [ncbi.nlm.nih.gov]

  Digital rectal examination is important in order to feel for a rectal mass, its location and relationship to the anal sphincters, its fixity to adjacent structures and to feel for any enlarged extrarectal nodule. [surgwiki.com]

• Photosensitivity

  Adverse events were reported by direct questioning of all patients; skin photosensitivity, changes in biochemical tests of liver function, blood pressure and heart rate, and the occurrence of GI symptoms (nausea, vomiting) were recorded for 5 patients [ncbi.nlm.nih.gov]

• Alopecia

  NonHodgkins Lymphomas 1247 Multiple Myeloma 1276 Practice of Oncology 1288 Superior Vena Cava Syndrome 1291 Central Nervous System Emergencies 1299 Metabolic Emergencies in Oncology 1312 Surgical Emergencies 1323 Oral Complications of Cancer Therapy 1340 Alopecia [books.google.es]

Adenomatous Polyposis Peutz-Jeghers Syndrome Other Problems to be Considered: Adenocarcinoma Tubular adenoma Cowden disease Granular cell tumor Hyperplastic polyp Inflammatory polyps Juvenile polyps Lymphoid polyps Mucosal prolapse Solitary rectal ulcer Workup [suprepkit.com]

You may be referred to an enterostomal therapist (a health care professional, often a nurse, trained to help people with their colostomies) as part of your initial workup. [healthywomen.org]

A prompt diagnosis plays an important role in the treatment of McKittrick-Wheelock syndrome. [ncbi.nlm.nih.gov]

As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. [books.google.es]

Stage for stage, right-sided colonic cancers tend to have a better prognosis than left-sided cancers. Prognosis Tumour stage is the main determinant ( Table 28, “Prognosis in colorectal cancer” ) of prognosis. [surgwiki.com]

The prognosis of IIIA approaches that of IIB etc. This is not yet in widespread use). The advent of the newer chemotherapy agents has made a significant impact on rectal cancer prognosis. [myvmc.com]

These have a worse prognosis than non-mucinous carsinomas. Photomicrograph of a primary mucinous adenocarcinoma. Click to enlarge. [oncolex.org]

Villous adenomas have a worse prognosis and warrant closer follow-up. One needs only to remember the criteria for tubular adenomas and villous adenomas, as tubulovillous adenomas are what is left over. [librepathology.org]

What is the prognosis of rectal polyps? People with a history of polyps have an increased risk of developing polyps again in their lifetime and should have regular exams by a physician specially trained to treat diseases of the colon and rectum. [annapoliscolon.com]

It gives updated in formation on etiology - whether genetic or environmental, pathology, clinical features and treatments. It also gives information on screening, prevention and chemoprevention, where available. [books.google.ro]

Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps. Am. J. Clin. [mdpi.com]

(Etiology) Tubular Adenoma of the Colon is caused by genetic mutations that results in dysplasia Dysplasia is the phenomena of disordered growth of the epithelial lining of the colon. Genetic mutations lead to cell growths at abnormally high rates. [dovemed.com]

McKittrick-Wheelock syndrome: a rare etiology of acute renal failure associated to well-differentiated adenocarcinoma (G1) arising within a villous adenoma. Rom J Morphol Embryol. 2011;52(3 Suppl):1153–1156. [PubMed] [Google Scholar] 28. [ncbi.nlm.nih.gov]

Declarations Acknowledgements The authors would like to thank Kai-Tai Zhang, Department of Etiology and Carcinogenesis of Peking Union Medical College as the help of array CGH experiment. [bmcmedgenomics.biomedcentral.com]

Experimental evidence has supported the hypothesis that dietary fibre may protect against the development of CRC, although epidemiologic data have been inconclusive. [cochrane.org]

— all in Norway; the Department of Epidemiology, Harvard School of Public Health, Boston (M.L., M.K., Ø.H., H.-O.A., M.B.); and the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm (H.-O.A.). [nejm.org]

[…] colon polyp with at least low grade dysplasia Precursor to invasive adenocarcinoma Essential features Dysplastic nuclei (elongated and hyperchromatic pseudostratification) 25% villous component ICD coding K63.5 : colon polyp D12.6 : adenomatous polyp Epidemiology [pathologyoutlines.com]

Total colorectal adenoma 4538 10,130 Colorectal cancer Murtaugh (2004) [ 6 ] 1997–2002 952 1205 Journal of nutrition Two times Murtaugh (2005) [ 7 ] 1991–2002 2298 2749 Journal of nutrition Butler (2003) [ 8 ] 1996–2000 620 1038 American Journal of Epidemiology [mdpi.com]

Clinical, autopsical, and epidemiological studies provide evidence of adenoma-to-carcinoma progression. The mean age of adenoma diagnosis is 10 years earlier than with carcinoma, and progression to carcinoma takes a minimum of 4 years. [emedicine.medscape.com]

[…] undergoing colonoscopy are found to have at least one adenoma ( N Engl J Med 2006;355:2551 ) Men more commonly affected than women ( Gastrointest Endosc 2011;74:135 ) Sites Found more commonly in the left colon and rectum compared with other polyps Pathophysiology [pathologyoutlines.com]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. [medlineplus.gov]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, and Management. 6th ed. Philadelphia: WB Saunders; 1997. 467-71. Mandel JS, Bond JH, Church TR, et al. [emedicine.medscape.com]

Sleisinger & Fordtran's Gastrointestinal and liver disease; pathophysiology, diagnosis, management. 6th ed. Philadelphia: Saunders, 1998. 11. Launoy G, Smith TC, Duffy SW, Bouvier V. [aafp.org]

Pathophysiology: Adenomas are believed to have an abnormal process of cell proliferation and apoptosis. The proliferative component is not confined to the crypt base and accumulates onto the surface and infolds downward. [suprepkit.com]

Combined ESD and TAMIS is effective in patients with benign and early neoplastic lesions of the anorectum extending above the dentate line with concomitant hemorrhoids and can prevent complications. [ncbi.nlm.nih.gov]

Prevention If you have a history of polyps in your colon, you’re more likely to get colon cancer. Screening is your best way to prevent that. Doctors generally recommend getting your first colonoscopy at age 50. [webmd.com]

He had multiple cardiac co-morbidities that prevented curative surgical resection. The endoscopic assessment was performed to exclude foci of cancer. [bli.eu]

Prevention of colorectal cancer by colonoscopic polypectomy. The national Polyp Study Workgroup. N Engl J Med 1993; 329 : 1977-81. O'Brien MJ, Winawer SJ, Zauber AG, Gottlieb LS, Sternberg SS, Diaz B, et al. [degruyter.com]

"Screening for Colorectal Cancer" in Guide to Clinical Preventative Services, 2nd Edition, Report of the U.S. Preventative Services Task Force, U.S. [labtestsonline.it]