Presentation
Clinical History 76 year old female presents with painful defecation, rectal bleeding and iron deficient anaemia. Lower GI endoscopy revealed a rectal mass. [eurorad.org]
The patient did not present important complications in the immediate postoperative period. [scielo.br]
In the case of our patients, the most common symptom at initial presentation was abdominal pain. Only one out of five patients was asymptomatic at presentation, and his tumor was discovered incidentally on routine follow-up. [jgo.amegroups.com]
Case presentation This case report describes the presentation of leiomyosarcoma of the rectum. A 30-year-old man from the north of Morocco presented with rectorrhagia and constipation. [jmedicalcasereports.biomedcentral.com]
Thirty-two years later, she presented with signs of rectal bleeding. [hindawi.com]
Immune System
- Abdominal Lymphadenopathy
A CT scan with intravenous enhancement showed no signs of neither distant metastases neither thoracic or intra-abdominal lymphadenopathy. [hindawi.com]
Entire Body System
- Turkish
Turkish J Cancer 2001;31:131-4. Rao BK, Kapur MM, Roy S. Leiomyosarcoma of the colon: a case report and review of the literature. Dis Colon Rectum 1980;23:184-90. [PubMed] Baker HL Jr, Good CA. [jgo.amegroups.com]
Respiratoric
- Aspiration
Tissue sample was obtained with fine-needle aspiration that showed mesenchymal myoid cells that did not stain for CD117, chromogranin, or synaptophysin. Smooth muscle actin (SMA) was focally positive. [liebertpub.com]
Some cases of hepatic leiomyosarcoma diagnosed by fine-needle aspiration cytology have been reported[13]. [ncbi.nlm.nih.gov]
A fine needle aspiration of the liver lesion was performed and revealed a spindle cell tumor. The patient underwent a complete colonoscopy, which identified a right colonic mass. [jgo.amegroups.com]
Gastrointestinal
- Rectal Pain
Case presentation A 90-year-old man presented in 2013 with bright red bleeding per rectum and rectal pain. Thirteen years prior, he was diagnosed with a T2 N0 stage 2 squamous cell anal cancer after symptoms of rectal bleeding. [ncbi.nlm.nih.gov]
Liver, Gall & Pancreas
- Hepatomegaly
Physical examination revealed hepatomegaly. The patient had a low hemoglobin of 9.2 g/dL (range, 14-18 g/dL) and platelet count of 89×109/L (range, 130×109-400×109/L). [jgo.amegroups.com]
- Liver Mass
CT scan revealed a large 12 cm × 9 cm mass in the right lobe of the liver with other small lesions in the same lobe (Figure 2). Liver biopsy showed metastatic leiomyosarcoma. A colonoscopy identified a mass in the sigmoid colon. [jgo.amegroups.com]
Neurologic
- Peripheral Neuropathy
We selected FOLFIRI plus bevacizumab for adjuvant chemotherapy with the expectation of an effect of irinotecan on the leiomyosarcoma and because the patient developed grade 3 peripheral neuropathy with mFOLFOX6. [ncbi.nlm.nih.gov]
Workup
Biopsy
- Liver Biopsy
Colonoscopy with tumor biopsy remains the most important diagnostic modality (24). [jgo.amegroups.com]
Treatment
Due to its rarity, the standard treatment has not been defined. The purpose of this study was to present the follow-up of a patient with leiomyosarcoma of medium rectum submitted to exclusive operative treatment. [scielo.br]
Treatment The patient was offered surgical management via abdominoperineal resection, but he declined. [ncbi.nlm.nih.gov]
In regard to prognostic features and risk factors, the standard treatment for most types of cervical cancer represents a combination of surgical treatment and radiation therapy, such as external beam radiation therapy and brachytherapy. [hindawi.com]
Given the uncommon nature of this tumor and the controversy about its treatment we report one case and review the literature in an attempt to report a particular evolution and to discuss the most appropriate treatment. [jmedicalcasereports.biomedcentral.com]
Prognosis
Prognosis is poor. Survival rates vary and depend of tumor staging. We report a patient case complaining of recurrent episodes of rectal bleeding and pelvic mass due to a rectal leiomyosarcoma, he had surgery with sphincter preserving. [journalijdr.com]
Prognosis is also poor; tumor size, histological grade, mitotic index, and local staging are the most known prognosis factors. [jmedicalcasereports.biomedcentral.com]
Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol 2010;28:2064–9 [PMC free article] [PubMed] [Google Scholar] 4. Singer S, Maki RG, O'Sullivan B. Soft tissue sarcoma. [ncbi.nlm.nih.gov]
Leiomyosarcoma seems to have a better prognosis than the GIST with the same index of mitoses8. [scielo.br]
A collected series of cases, and a case report of rectal leiomyosarcoma are presented to emphasize the remarkably poor prognosis especially when the lesion is treated by local excision. [link.springer.com]
Prevention
It also might prevent the recurrence of rectal LMS and contribute to prolong patient survival. Conclusions We reported a case of LMS in the lower rectum. It was successfully removed by the hybrid method of laparoscopic and TaTME approaches. [surgicalcasereports.springeropen.com]
Soerjomataram, “Second primary cancers in survivors of cervical cancer in the Netherlands: implications for prevention and surveillance,” Radiotherapy and Oncology, vol. 111, no. 3, pp. 374–381, 2014. View at: Publisher Site | Google Scholar C. J. [hindawi.com]
Second primary cancers in survivors of cervical cancer in the Netherlands: implications for prevention and surveillance. Radiotherapy and Oncology. 2014;111(3):374–381. doi: 10.1016/j.radonc.2014.04.011. [PubMed] [CrossRef] [Google Scholar] 26. [ncbi.nlm.nih.gov]