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Recurrent Acute Pancreatitis


Presentation

  • Case 3 patient is a 29-year-old woman presenting with recurrent pancreatitis and epigastric pain.[ncbi.nlm.nih.gov]
Hunting
  • The hunt for microlithiasis in idiopathic acute recurrent pancreatitis: should we abandon the search or intensify our efforts? Gastrointest Endosc. 2002;55(2):286–93. PubMed CrossRef Google Scholar 55.[link.springer.com]
Recurrent Epigastric Pain
  • Case 2 patient is a 32-year-old woman presenting with periods of infertility, two previous spontaneous abortions, recurrent epigastric pain, and recurrent pancreatitis.[ncbi.nlm.nih.gov]

Workup

  • OBJECTIVES: The aim was to present the workup of patients with acute recurrent pancreatitis (ARP) for genetic analysis and electrophysiological testing.[ncbi.nlm.nih.gov]
  • On this last admission, as part of workup, a blood sample was taken for metabolic screening. This was analyzed by tandem mass spectrometry (MS/MS). The result revealed and confirmed the diagnosis of IVA.[atmph.org]

Treatment

Prognosis

  • If diagnosed early in the absence of distant metastases the prognosis of papillary somatostatinoma with tumour resection is excellent.[ncbi.nlm.nih.gov]
  • Prognosis RAP may lead to chronic pancreatitis and is associated with significant morbidity and impairment of quality of life. The documents contained in this web site are presented for information purposes only.[orpha.net]
  • Factors associated with poor prognosis are age over 60 years, male gender and tumor larger than 10 cm. The classification stage is the same in all exocrine pancreatic carcinoma cells.[actagastro.org]
  • Factors associated with poor prognosis are age over 60 years, male gender and tumor larger than 10 cm. The classification stage is the same in all exo- crine pancreatic carcinoma cells.[redalyc.org]
  • Acute pancreatitis: value of CT in establishing prognosis. Radiology. 1990;174:331–6. 20. Leung TK, Lee CM, Lin SY, Chen HC, Wang HJ, Shen LK, et al.[aafp.org]

Etiology

  • Common etiological factors were biliary disease (37%), pancreas divisum (8.5%) and alcohol (6.4%). Multiple etiologies were seen in 7% of cases, and no cause was found in 32.4%.[ncbi.nlm.nih.gov]

Epidemiology

  • The first paper evaluates epidemiological data on the impact of alcohol consumption on total morbidity and mortality.[books.google.com]
  • Summary Epidemiology The estimated prevalence of RAP is approximately 1 in 10,000 and the disease predominantly affects males in their forties. The true incidence, however, remains unknown due to geographical, etiological, and diagnostic variations.[orpha.net]
  • The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology 2013;144:1252-61. Zhang W, Shan HC, Gu Y. Recurrent acute pancreatitis and its relative factors. World J Gastroenterol 2005;11:3002-4.[smj.si.mahidol.ac.th]
  • Discussion on the epidemiology of acute pancreatitis is limited with the difficulties of making the correct diagnosis and the difficulties of attaching a pancreatitis to one of the two forms.[karger.com]
Sex distribution
Age distribution

Pathophysiology

  • This is followed by a critical appraisal of the effect of moderate drinking on the risk and pathophysiological mechanisms of gastrointestinal diseases and of certain health benefits of moderate alcohol consumption.[books.google.com]
  • Santorinicele without pancreas divisum pathophysiology: Initial clinical and radiographic investigations. BMC Gastroenterol 2013;13:62. [ PUBMED ] [Figure 1], [Figure 2], [Figure 3], [Figure 4][jdrntruhs.org]
  • The pathophysiology of choledochoceles causing acute pancreatitis includes: (1) Obstruction of pancreaticobiliary reflux resulting in increased pressure in duct or reflux of bile into the pancreatic duct. (2) Stone in cyst causing external compression[jdeonline.in]
  • Autoimmune pancreatitis is an altogether different disease both from the point of pathophysiology and clinical presentation.[tropicalgastro.com]

Prevention

  • Moreover, plasma-pheresis may be useful for preventing acute pancreatitis.[ncbi.nlm.nih.gov]

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