Some common general symptoms of anemia include: Pale lips, skin and hands Fatigue Lack of energy Decreased exercise tolerance Irritability Common symptoms of hemolysis (increased red blood cell breakdown) include: Jaundice Scleral icterus (yellow eyes [danafarberbostonchildrens.org]

[…] a single chromosome (α/α / ), children of these individuals are at higher risk of HbH disease or Hydrops Fetalis Blacks: one from each of the two chromosomes (α/ α/ ) Symptomatic α-thalassemia is relatively common in Asian populations and rare in black [slideplayer.com]

PubMed Hydrops fetalis associated with homozygosity for Hb Adana [alpha59(E8)Gly-- Asp (alpha2)]. Hemoglobin. 2010;34(4):394-401. doi: 10.3109/03630269.2010.493405. PubMed Alpha thalassaemia in Indonesia: phenotypes and molecular defects. [eijkman.go.id]

Reference Range : M: 30-400 ng/mL; F: 10-145 ng/mL Free Erythrocyte Protoporphyrins (FEP) This is a screening test, mainly used in pediatric practice to detect iron deficiency and lead poisoning. [ucsdlabmed.wikidot.com]

Quantitative Iron in Liver Measurement of iron in liver biopsies is also very helpful in the diagnosis of hemochromatosis, especially in cases in which the serum iron and iron-binding capacity may be borderline abnormal. [ucsdlabmed.wikidot.com]