Presentation
Results: AL was present in 29 (24.0%) participants. [erj.ersjournals.com]
Bone disease in children with IBD seems to be secondary to muscle wasting, which is already present at diagnosis. With longer disease duration, bone adapts to the lower muscle CSA. [ncbi.nlm.nih.gov]
In view of the comparable average figures for height and weight between subjects in the present study and the general population in Japan, the results of the present study could be extrapolated to the Japanese population as a whole. [journals.plos.org]
RESULTS: Patients were stratified according to the presence/absence of low muscle mass, low muscle strength or both conditions: 58 patients (54%) had low muscle mass, 57 (53%) low muscle strength while both conditions (true sarcopenia) was present in [academic.oup.com]
In the present study, we aimed to investigate specifically whether there is a relationship between the muscle reflex activation and abnormality in the skeletal muscle mass of the limbs of patients with CHF assessed by dual-energy x-ray absorptiometry. [circ.ahajournals.org]
Entire Body System
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Impaired Exercise Tolerance
exercise tolerance. 3 A clear association exists between symptom severity, NYHA functional class, muscle wasting, 2 and ergoreflex overactivity. 3 Clinical Perspective p 134 Skeletal musculature becomes abnormal in CHF, which may contribute to exercise [circ.ahajournals.org]
Neurologic
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Hyperactivity
Putative contribution of prostaglandin and bradykinin to muscle reflex hyperactivity in patients on ACE-inhibitor therapy for chronic heart failure. Eur Heart J. 2004 ; 25 (20): 1806–1813. [circ.ahajournals.org]
Workup
Colonoscopy
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Colitis
Learn more Become a Foundation Member By becoming a Professional Member of the Crohn's & Colitis Foundation, you will establish yourself as a leader and specialist in Crohn's disease and ulcerative colitis. [journals.lww.com]
METHODS: In a cross-sectional study, pQCT of the forearm was applied in 143 IBD patients (mean age 13.9 /- 3.5 years); 29% were newly diagnosed, 98 had Crohn's disease, and 45 had ulcerative colitis. [ncbi.nlm.nih.gov]
Treatment
Valuable advice is provided on treatment, and treatment effects, such as metabolic effects, adipose tissue alterations, and impact on aging, are fully explored. [books.google.com]
Read Now VIDEO ABSTRACT Thiopurine treatment in ulcerative colitis: a critical review of the evidence for current clinical practice VIDEO ABSTRACT A survey study of gastroenterologists' attitudes and barriers towards therapeutic drug monitoring of anti-TNF [journals.lww.com]
Continued Other treatments under investigation for sarcopenia include: Testosterone supplements Growth hormone supplements Medication for treatment of metabolic syndrome (including, insulin -resistance, obesity, and hypertension ). [webmd.com]
One physical therapy treatment that combats these effects, with better overall outcomes, is whole body vibration. It is also a great treatment for various other conditions and situations, too. [rehabalternatives.com]
"Comprehensive Approach to Sarcopenia Treatment". Curr Clin Pharmacol. 9 (2): 171–80. doi : 10.2174/1574884708666131111192845. PMID 24219006. [en.wikipedia.org]
Prognosis
INTRODUCTION AND AIMS: Sarcopenia is a reliable marker of frailty and poor prognosis among elderly individuals. [academic.oup.com]
[…] atrophy results from a co-morbidity of several common diseases, including cancer, AIDS, congestive heart failure, chronic obstructive pulmonary disease, renal failure, and severe burns ; patients who have " cachexia " in these disease settings have a poor prognosis [en.wikipedia.org]
Interventions specifically targeted at reversing peripheral muscle wasting such as exercise training have been shown to improve muscle function, 4 reduce ergoreflex activity, 1 and improve prognosis. 5 Nevertheless, there has been no direct evidence of [circ.ahajournals.org]
Etiology
J Nutr 127:990S-991S, 1997 Rolland Y, Czerwinski S, Abellan Van Kan G, et al: Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives. J Nutr Health Aging 12:433-450, 200 Mayo clinic. Muscle loss and aging. [physio-pedia.com]
Epidemiology
"Epidemiology of sarcopenia among the elderly in New Mexico". Am J Epidemiol. 147 (8): 755–63. doi : 10.1093/oxfordjournals.aje.a009520. PMID 9554417. [ non-primary source needed ] Fried LP, Tangen CM, Walston J, et al. (2001). [en.wikipedia.org]
Int J Obes 2002 ; 26 : 1349 – 55. 20 Human body composition and the epidemiology of chronic disease. [ajcn.nutrition.org]
Pathophysiology
The genetic basis of the syndrome is fully considered, and all aspects of the pathophysiology of IGF-I deficiency are described. Data derived from the recently generated mouse model of LS are reviewed and compared with the human LS experience. [books.google.com]
Patients with chronic heart failure (CHF) are characteristically limited by symptoms of breathlessness and fatigue, the pathophysiology of which remains unclear. [circ.ahajournals.org]
Prevention
The increased mortality risk was mainly accounted for by low muscle strength suggesting that assessments, and preventive and therapeutic interventions, targeting muscle strength deserve more attention in dialysis patients. [academic.oup.com]
The good news is that they’ve also discovered how to build the cartilage back up and prevent further breakdown. [flexonline.com]
Department of Health and Human Services, Centers for Disease Control and Prevention; 2002. www.cdc.gov/nccdphp/dnpa/physical/growing_stronger/growing_stronger.pdf. Accessed August 10, 2010. 7. [uspharmacist.com]
HMB supplementation may be useful in the prevention of muscle atrophy induced by bed rest or other factors. [en.wikipedia.org]
Any strength training can help prevent or treat sarcopenia. [berkeleywellness.com]