Edit concept Question Editor Create issue ticket

Renal Adenoma

Adenoma of Kidney


Presentation

  • The findings are presented along with a review of the literature. There were 4 males and 1 female ranging in age from forty-two to sixty-three years. Each presented with a mass on excretory urography, and 1 contained calcification.[ncbi.nlm.nih.gov]
  • Several of these markers might be present in each single case. The interpretation is that their ultrastructural characteristics do not indicate an origin from a special segment of the nephron.[ncbi.nlm.nih.gov]
  • Previously reported infants with malignant and benign solid tumors causing humoral hypercalcemia have presented with large abdominal masses.[ncbi.nlm.nih.gov]
  • Abstract Autopsy findings of a 34-year-old Japanese male with stomach cancer in a renal allograft are presented.[ncbi.nlm.nih.gov]
  • In this issue of the Journal, Mazal et al. 1 present compelling evidence that these unusual adenomas originate from . . . Julie R. Ingelfinger, M.D.[nejm.org]
Clubbed Finger
  • On admission, clubbed fingers richitic rosaries and a palpable node in the neck were the major physical findings. Laboratory examinations revealed hypercalcemia had elevated levels of plasma parathyroid hormone (PTH) in a c-terminal assay.[ncbi.nlm.nih.gov]
Abdominal Mass
  • Previously reported infants with malignant and benign solid tumors causing humoral hypercalcemia have presented with large abdominal masses.[ncbi.nlm.nih.gov]
  • Classic symptoms - combination of flank pain, hematuria and a palpable abdominal mass occur in less than 10%. In about 30% of patients, there are unusual abnormalities seen that may be due to presence of renal cell carcinoma.[clevelandurology.net]
  • See separate articles Abdominal Masses, Loin Pain and Haematuria which discuss the various causes. Investigations Urinalysis, cytology, culture and sensitivity should be performed to exclude urinary tract infection.[patient.info]
Xanthoma
  • , based on criteria for papillary renal cell carcinoma Note : small tumors of clear cells are considered to be small renal cell carcinomas, clear cell type and with malignant potential Microscopic (histologic) images Case of the Week #43 AFIP images Xanthoma[pathologyoutlines.com]
Suggestibility
  • This study identifies two distinct groups of adenomas according to size, histological type and extent of sclerosis, and suggests that small adenomas of the mixed tubulopapillary type and with basophilic cells have little or no malignant potential.[ncbi.nlm.nih.gov]
  • Using 5 cases as examples, a suggested approach is outlined.[ncbi.nlm.nih.gov]
  • Renal adenomas had predominant histochemical features of the distal tubulus, suggesting differentiation to a distal tubulus-like histology.[ncbi.nlm.nih.gov]
  • However, as demonstrated by this case and others, metastasis can occur, therefore, it is suggested that the term renal adenoma no longer be used.[ncbi.nlm.nih.gov]
  • AVS is a technically challenging test, but lateralization suggests ipsilateral adenoma. F.[clinicaladvisor.com]

Workup

Multiple Renal Cysts
  • Bilateral multiple renal cysts in a 46-year-old man were pointed out incidentally by ultrasonography. Some of the left renal lesions were considered to be RCC, and left radical nephrectomy was performed accordingly.[ncbi.nlm.nih.gov]

Treatment

  • The treatment of the renal adenoma is based on the imaging of the tumor. But this method of ascertaining the nature and size of the adenoma is inadequate. In this case, more sophisticated technology is applied for the treatment of the disease.[healthdrip.com]
  • One should use the criteria of size, gross characteristics, a frozen section biopsy, and the status of the other kidney to decide between tumor excision, nephrectomy, and no further treatment.[ncbi.nlm.nih.gov]
  • Noninvasive treatment approaches are usually preferred because the risks for the patient are much lower.[wisegeek.com]
  • Previously, it was thought that small (less than 3cm) solid tumours of the kidney were benign because they rarely metastasized; their histological similarity to renal cell carcinoma now results in similar treatment to their malignant relation i.e. surgical[gpnotebook.co.uk]

Prognosis

  • Prognosis Metastases have occurred with very small papillary primaries, but the prognosis is generally excellent. References 1 Renshaw, A. A. (2002). "Subclassification of renal cell neoplasms: an update for the practising pathologist."[e-immunohistochemistry.info]
  • Such tumors involve special aspects of both diagnosis and therapy and also have a distinctive prognosis.[books.google.de]
  • Prognosis is excellent with surgical Therapy. Postoperatively patients need to be monitored with serial imaging and biochemical tests [ 1 ].[hoajonline.com]
  • Prognosis [ 1 ] Kidney cancer survival is improving and has increased in the last 40 years in the UK. 50% of people diagnosed with kidney cancer in England and Wales survive for ten years or more (2010-11). 56% of people diagnosed with kidney cancer in[patient.info]

Etiology

  • Nephrogenic adenoma of the bladder after kidney transplantation: spontaneous improvement with azathioprine removal: surgical trauma and cytomegalovirus infection as possible etiologic factors. J Urol 1983 ;130: 1183 - 1185 10. Young RH, Scully RE.[nejm.org]

Epidemiology

  • Epidemiology These are very common incidental findings. They are found more commonly in kidneys containing renal cell carcinoma or oncocytoma, particularly the hereditary form of papillary renal cell carcinoma.[e-immunohistochemistry.info]
  • Definition / general Low grade (usually) neoplasm also known as renal cortical adenoma Epidemiology Commonly found at autopsy: 10% at age 21 - 40 years, 40% at age 70 - 90 Increasing numbers during life are being detected with more widespread whole body[pathologyoutlines.com]
  • Disease Renal papillary adenoma Epidemiology Papillary adenomas are common. They have been reported in 7% of nephrectomy specimens and 10-40% of autopsy kidneys.[atlasgeneticsoncology.org]
  • Malignant Kidney Tumors Renal cell carcinoma (85%) Transitional cell carcinoma (8%) Sarcomas (rare) Wilm's Tumor (affects infants and children, rare) Renal Cell Carcinoma Epidemiology Growing health problem in the USA and around the world. 52,000 new[clevelandurology.net]
Sex distribution
Age distribution

Prevention

  • No other predisposing factors have been defined, and prevention is not possible. What are the symptoms? Most patients with an adrenal adenoma will have no symptoms caused by the adenoma.[netdoctor.co.uk]
  • The combined use of two drugs that are prescribed for other conditions, eflonithine and sulindac, may prevent the development of adenomas or the recurrence of colon cancer.[encyclopedia.com]
  • To learn more or modify/prevent the use of cookies, see our Cookie Policy and Privacy Policy . 他疾患の精査中, 偶然発見された腎腺腫の1例を報告した。症例は78歳男性で, 4年前の膀胱癌に対するBCG膀胱内注入療法後の定期的な膀胱鏡検査でビロード状粘膜を指摘された。腹部造影CTに膀胱癌の転移を示唆する所見はなかったが, 右腎下極に動脈相で濃染する径10mmの腫瘍性病変を認めた。[researchgate.net]
  • There appear to be several factors and some are preventable, especially smoking and obesity. [ 1 ] Risk factors Risk factors include lifestyle, smoking, obesity and hypertension. [ 2 ] Other risk factors include long-term renal dialysis, tuberous sclerosis[patient.info]
  • Appropriate Prophylaxis and Other Measures to Prevent Readmission NA VII. What's the evidence? Arnaldi, G, Angeli, A, Atkinson, AB. “Diagnosis and complications of Cushing's syndrome: A consensus statement”.[clinicaladvisor.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!