Presentation
Renal metastases of thyroid carcinomas are rare and often present as a primitive unilateral renal mass. [ncbi.nlm.nih.gov]
Three years later before the patient was lost to follow-up, no evidence of recurrence was present. [scielo.br]
Respiratoric
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Sputum
Case presentation A 53-year-old Chinese woman presented symptoms of cough, bloody sputum at the first visit. [mrmjournal.biomedcentral.com]
In the present study, a case of lung squamous cell carcinoma causing isolated unilateral renal metastasis is reported. 2 Case presentation A 74-year-old Chinese male complained of coughing and bloody sputum at the first visit. [journals.lww.com]
Gastrointestinal
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Left Flank Pain
A 62-year-old man who had undergone hepatectomy for HCC presented 6 years after initial diagnosis with left flank pain and was found on CT and MRI to have a tumor in the left kidney. [ncbi.nlm.nih.gov]
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Pelvic Mass
Abstract A 44-year-old woman presented with a large pelvic mass. Pathology revealed a granulosa cell tumour of the left ovary. The patient was followed after surgery with inhibin B levels and interval imaging. [ncbi.nlm.nih.gov]
Cardiovascular
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Hypertension
March 06, 2018 ; 90 (10) Resident & Fellow Section Muhammad Taimur Malik, Syed Jaffar Kazmi, Scott Turner First published March 5, 2018, DOI: A 75-year-old man with hypertension presented with 2 weeks' history of left lower extremity numbness and weakness [n.neurology.org]
Case Report A 74-year-old Caucasian man with a history of hypertension and stage I clear cell type renal cell cancer underwent right nephrectomy in 2004. [karger.com]
The overall survival for hypertensive patients with metastatic renal cell carcinoma receiving angiotensin system inhibitors was 27 months vs 17 months for non–angiotensin system inhibitor users. [ascopost.com]
[…] with and without hypertension. [intechopen.com]
The adverse events with bevacizumab included proteinuria, hypertension, and bleeding. [jhoponline.com]
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Palpitations
While patients with cardiac metastases are often asymptomatic, they can present with nonspecific symptoms, such as palpitations, chest pain, shortness of breath, and even syncope [ 6 ]. Hypertension is the most common cardiac presentation of RCC. [karger.com]
Eyes
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Foreign Body Sensation
She had symptoms of a foreign body sensation at the back of her throat, and oropharyngeal examination revealed uvular erythematous mass with vascularity. Uvular biopsy and complete excision were performed, which revealed metastatic RCC. [dovepress.com]
Musculoskeletal
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Back Pain
A 34-year-old man with an extensive medical history received a CT scan for chronic leg and back pain. Imaging revealed a single, enhancing 8-cm mass in the upper pole of the right kidney. [ncbi.nlm.nih.gov]
Bones of the lower back lower back pain weill cornell brain and spine center template. Bones of the lower back anatomy of the spine patients depuy synthes companies free. [healthday.info]
Signs and symptoms of renal cell cancer may include the following: Hematuria ( blood in the urine ) Lower back pain or pain in the flank (side or back above the waist) that will not go away Noticeable lump in the flank Weight loss Fatigue (feeling tired [emedicinehealth.com]
Signs and symptoms of transitional cell cancer of the renal pelvis and ureter include blood in the urine and back pain. [cancer.gov]
Neurologic
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Neglect
Conclusions Renal metastatic tumors from squamous cell lung carcinoma are very rare and easy to be neglected, however we should take into account also the possibility of a metastasis from this tumor when a renal mass is detected. [mrmjournal.biomedcentral.com]
Urogenital
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Hematuria
The man underwent radical nephrectomy (to prevent hematuria), splenectomy and biopsies in liver and small intestine. After surgery the patient refused adjuvant chemotherapy. [ncbi.nlm.nih.gov]
The most common presenting symptom of bladder metastasis is hematuria. In a patient with synchronous bladder metastasis, hematuria may be wrongly attributed to collecting system infiltration of RCC. [jcmtjournal.com]
Renal metastases frequently do not present clinical symptoms and many patients have no hematuria or hyperazotemia. [mrmjournal.biomedcentral.com]
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Flank Pain
Abstract A 50-year-old man, with a history of right lower lobectomy for pulmonary adenocystic carcinoma, presented with chronic flank pain due to a large mass in the right kidney. [ncbi.nlm.nih.gov]
Only a minority of patients present with the classic triad of flank pain, hematuria, and a renal mass, signifying advanced disease progression with poor prognosis. 6 Earlier detection through imaging such as abdominal CT and ultrasound may help improve [retinatoday.com]
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Vaginal Bleeding
We achieved good haemostatic control of vaginal bleeding by palliative radiotherapy. [omicsonline.org]
She was readmitted because of vaginal bleeding. On examination a 4 x 5 cm mass was found arising from the lower one-third of the vagina. [panafrican-med-journal.com]
Workup
Metastatic workup was done: contrast-enhanced computed tomography of whole abdomen and pelvis was within normal limits. [jcmtjournal.com]
Further, staging workup showed bilateral pulmonary metastasis. She was given palliative Radiotherapy 30 Gy in 10 fractions followed by Sunitinib 50 mg oral daily, but patient died of progressive disease 4 months of palliative radiotherapy. [omicsonline.org]
The patient was referred to a urologist and had a complete workup, which included a CT scan of his chest, abdomen, and pelvis, appropriate blood work and a urinalysis, and he underwent a left radical nephrectomy. [targetedonc.com]
CNB has a higher sensitivity and a lower false negative rate than FNA, and was less likely to require a further diagnostic workup, especially for metastatic thyroid nodules [ 15 ]. [e-ultrasonography.org]
With respect to the diagnostic workup, brain imaging was done routinely in the Munich centre, whereas in the two Swedish centres brain imaging was done only if clinical signs suspicious of brain involvement were present. [tandfonline.com]
X-Ray
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Pericardial Effusion
Complications of therapy, such as tumor necrosis, extracardiac spread, and pericardial effusion, can be identified with cardiac MRI. [karger.com]
T Wave
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T Wave Inversion
An electrocardiogram showed normal sinus rhythm, with T wave inversions in leads II, III, avF, and V4-V6. [karger.com]
Treatment
Cryoablation is successfully performed as a treatment for small renal cancers. The occurrence of a solitary renal metastasis from lung cancer is an uncommon finding entailing a limited knowledge on the choice of its optimal treatment. [ncbi.nlm.nih.gov]
Treatment The patient rejected all treatments for metastases except the steroid therapy. [wjgnet.com]
Outcome with local treatment for LM The characteristics of the 9 patients who underwent local treatment for LM are summarized in Table V. [spandidos-publications.com]
Physicians who attempt this treatment in the future need to be aware of the possibility of cardiac wall perforation from treatment-induced necrosis. [karger.com]
Prognosis
Factors affecting prognosis We next attempted to identify the clinical factors affecting the prognosis of RCC patients with LM. [spandidos-publications.com]
Most of these diseases exhibit slow progression and have a favorable prognosis. Distant metastasis caused by thyroid microcarcinoma is uncommon, and is usually found in the lung or bone. [ncbi.nlm.nih.gov]
This study suggests that the patients with decreased E-CD expression may be associated with metastasis, resulting in poor prognosis. [nature.com]
An oral metastasis implies a serious prognosis, as in the majority of patients there is multiple organ involvement at the time of diagnosis. [roderic.uv.es]
P Keywords: renal cell cancer, sorafenib, targeted therapy, prognosis This work is published and licensed by Dove Medical Press Limited. [dovepress.com]
Etiology
Therapy was initially complicated by a hospital admission for fever and confusion of uncertain etiology, but sunitinib was subsequently resumed and was well tolerated. [ncbi.nlm.nih.gov]
Etiology/Causes If a patient is diagnosed with renal cancer, their first question might be “how did this happen?” [physio-pedia.com]
"Etiology of Renal Cell Carcinoma: Incidence, Demographics, and Environmental Factors". Renal Cell Carcinoma Clinical Management. Humana Pr Inc. pp. 3–22. ISBN 978-1-62703-061-8. Lane, Brian R. (2013). [en.wikipedia.org]
Epidemiology
It provides an overview of new information concerning epidemiology, molecular and immunologic characteristics, as well as surgical therapy. Particular focus is given to the latest diagnostic tests and genetic counseling. [books.google.de]
[…] in Renal Cell Carcinoma Edited by Robert Amato Next chapter Prognostic Factors in Renal Cell Carcinoma: An Evaluation of T-Stage, Histopathological Grade, p53, Ki-67, COX-2, and Her-2 Expressions By Minna Kankuri-Tammilehto Related Book First chapter Epidemiology [intechopen.com]
The book begins with a review of the epidemiology, pathology, and biology of renal cell carcinoma followed by chapters on specific targeted therapies and managing complications. [books.google.ro]
Renal Cell Carcinoma Epidemiology Renal Cell Carcinoma Symptoms Renal Cell Carcinoma Diagnosis [news-medical.net]
Demographic and epidemiological perspectives. Hematol Oncol Clin North Am 2000; 14 (1): 17–23). [siog.org]
Pathophysiology
Objective: In this review we discuss pathophysiology of tumor metastasis, diagnosis, management and Case examples of metastatic renal cell carcinoma. Conclusion: Incidence of metastatic renal carcinoma is increasing. [mendeley.com]
Effective strategies to prevent and treat AD remain elusive despite major efforts to understand its basic biology and clinical pathophysiology. Significant investments in therapeutic ... [annualreviews.org]
Coleman RE Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 2001 ; 27 : 165 -76. [clincancerres.aacrjournals.org]
[…] sickle cell disease. [23] The most significant disease affecting risk however is not genetically linked – patients with acquired cystic disease of the kidney requiring dialysis are 30 times more likely than the general population to develop RCC. [24] Pathophysiology [en.wikipedia.org]
Tumor angiogenesis: pathophysiology and implications for contrast-enhanced MRI and CT assessment. Abdom Imaging 2006 ;31(2):188–193. Crossref, Medline, Google Scholar 54 Verma S, Rajesh A, Fütterer JJ et al.. [pubs.rsna.org]
Prevention
The man underwent radical nephrectomy (to prevent hematuria), splenectomy and biopsies in liver and small intestine. After surgery the patient refused adjuvant chemotherapy. [ncbi.nlm.nih.gov]
This case suggests that retrograde venous dissemination may be at the origin of vaginal metastasis of renal cell carcinoma and emphasized the preventive value of early ligature of renal vein. [panafrican-med-journal.com]
The injected agent can block the artery and prevent blood from getting through to the kidney and the tumor. The tumor cannot live without blood, and it dies. The procedure can be painful and cause fevers. [emedicinehealth.com]
Because you’re trying to prevent the first skeletal-related event. Dr. Yang: These data are very scant. [clincancerres.aacrjournals.org]
The sponges block the blood flow to the kidney and prevent the cancer cells from getting oxygen and other substances they need to grow. [cancer.gov]