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Reoviridae

Reovirus


Presentation

  • Along with a cursory presentation of the remaining genera, we give a concise update of recent findings on the genus Orthoreovirus.[ncbi.nlm.nih.gov]
  • The reverse genetics methods for BTV and RV are presented and compared to the previously described MRV methods.[ncbi.nlm.nih.gov]
  • This study demonstrates that seadornaviruses are genetically diverse, not restricted geographically to Southeast Asia and present in an aquatic environment.[hungary.pure.elsevier.com]
  • Reovirus phase I clinical trials have shown indications of efficacy and several phase I/II trials are ongoing at present.[ncbi.nlm.nih.gov]
  • . – PowerPoint PPT presentation Number of Views: 977 Avg rating: 3.0/5.0 less Transcript and Presenter's Notes Title: Reoviridae 1 (No Transcript) 2 (No Transcript) 3 Reoviridae Reoviruses Respiratory Enteric Orphan virus three serotypes that infect man[powershow.com]
Diarrhea
  • Application of this proportion to the World Health Organization estimates of diarrhea-related childhood deaths gives an estimated 611,000 rotavirus-related deaths ( Parashar UD. Rotavirus and severe childhood diarrhea.[web.archive.org]
  • Bluetongue Disease and Colorado Tick Fever Besides rotaviral diarrhea, one very famous disease that is of economic importance in this family is called bluetongue disease.[study.com]
  • Bluetongue Disease and Colorado Tick Fever Besides rotaviral diarrhea, one very famous disease that is of economic importance in this family is called bluetongue disease .[study.com]
  • All 3 types have been recovered from healthy children, from young children during outbreaks of minor febrile illness, and from children with diarrhea or enteritis.[web.stanford.edu]
  • […] rotavirus-B219)) 10 entries Rotavirus B (isolate RVB/Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus)) 9 entries Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1]) (RV-A) (Rotavirus A (strain Nebraska calf[viralzone.expasy.org]
Headache
  • […] oral/fomite transmission ISVP activated in gut and taken up in gut epithelium colorado tick fever -natural reservoir is small mammals -vector are ticks -human and deer are accidental hosts -infects hematopoietic cells persists in RBC -fever, chills, headache[quizlet.com]
  • Fever Headache Malaise Myalgia Nausea Vomiting After the prodoromal phase of the Erythema infectiosum (EI) (fifth disease), _____ often appears.[brainscape.com]
Meningism
  • Johansson PJ, Sveger T, Ahlfors K, Ekstrand J, Svensson L. (1996) Reovirus type 1 associated with meningitis. Scand J Infect Dis; 28:117–120. PubMed CrossRef Google Scholar 25.[doi.org]

Treatment

  • Early clinical trials of combinations of the injectable oncolytic reovirus therapy Reolysin (Oncolytics Biotech Inc) plus cytotoxic chemotherapies are ongoing, as are phase II trials of Reolysin as a single agent for the treatment of specific tumor types[ncbi.nlm.nih.gov]
  • Current mainstays in cancer treatment such as chemotherapy, radiation therapy, hormonal manipulation, and even targeted therapies such as trastuzumab (Herceptin) for breast cancer or erlotinib (Tarceva) for non-small cell lung cancer are limited by lack[ncbi.nlm.nih.gov]
  • Despite the ease of finding Reovirus in clinical specimens, their role in human disease or treatment is still uncertain. Some viruses of this family, such as Phytoreovirus and Oryzavirus, infect plants.[en.wikipedia.org]
  • Clinical cancer research : an official journal of… 2009 PURPOSE To test combination treatment schedules of reovirus and cisplatin chemotherapy in human and murine melanoma cell lines… (More) Zhou Guohui , WEN JingJung , CAI DeJiang , Li Peng , XU DongLin[semanticscholar.org]
  • “Viral treatments like reovirus are showing real promise in patient trials.[reuters.com]

Etiology

  • Conversely, rotaviruses (RVs), which are the major etiological agent of severe gastroenteritis in infants and children, have thus far only been modified using single-segment replacement methods.[ncbi.nlm.nih.gov]
  • Butel JS. (2000) Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease. Carcinogenesis; 21:405–426. PubMed CrossRef Google Scholar 2.[doi.org]

Epidemiology

  • Type of: arborvirus , arbovirus a large heterogeneous group of RNA viruses divisible into groups on the basis of the virions; they have been recovered from arthropods, bats, and rodents; most are borne by arthropods; they are linked by the epidemiologic[vocabulary.com]
  • The site is a SIB Swiss Institute of Bioinformatics web-resource for all viral genus and families, providing general molecular and epidemiological information. Reoviridae by WikiGenes.[microbes.info]
  • Much is now known about its ecological niche and life cycle in vertebrate and invertebrate hosts as well as the epidemiology, pathogenesis, and clinical course of infection in humans.[asmscience.org]
Sex distribution
Age distribution

Prevention

  • We provide New Zealanders with independent, factual information about vaccine-preventable diseases and the benefits and risks of immunisation.[immune.org.nz]
  • Prevents cell detecting viruses dsRNA & signalling infection - interferon response. ssRNA exits via holes in capsid to cytoplasm Once rotaviruses sense ssRNA is in the cytoplasm it initiates ……. Protein synthesis.[cram.com]
  • , Colorado State University, Fort Collins, CO 80523, USA 2 Department of Zoology, Entomology and Fisheries Sciences, Makerere University, Kampala, Uganda 3 Arboviral Diseases Branch, Division of Vector-borne Diseases, Centers for Disease Control and Prevention[mdpi.com]
  • Multivalent live vaccines, if properly administered, prevent infection with all the relevant serotypes.[web.archive.org]

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