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Respiratory Failure


Presentation

  • CONTEXT: Dyspnea has rarely been reported as a presenting symptom in patients with neuromyelitis optica (NMO).[ncbi.nlm.nih.gov]
  • CASE REPORT Our patient presented with hypercarbic respiratory failure. This is the first such reported case without signs of weakness elsewhere of which we are aware.[ncbi.nlm.nih.gov]
  • A case is presented of hypertensive cardiogenic pulmonary edema treated with high-dose nitroglycerin and includes a review of the literature.[ncbi.nlm.nih.gov]
  • CASE PRESENTATION: A 31-year-old, African woman in her second trimester of pregnancy presented to the emergency department with fever, shortness of breath and muscle weakness.[ncbi.nlm.nih.gov]
  • The authors present a case of diffuse intrinsic pontine glioma presenting in a newborn with stridor and respiratory distress that progressed to respiratory failure.[ncbi.nlm.nih.gov]
Intermittent Fever
  • We report a case of a patient with dyspnea, cough, and intermittent fever as well as ILD associated ASS in the absence of muscular involvement.[ncbi.nlm.nih.gov]
Myxedema
  • Central nervous system dysfunction: drug overdose- narcotics/sedatives brain-stem lesion metabolic disorders- myxedema, chronic metabolic acidosis central hypoventilation Peripheral nervous system dysfunction: Myasthenia gravis Guillain-Barre Syndrome[physio-pedia.com]
Weight Gain
  • Clinical signs may include any or all of the following: rapid weight gain, ascites, oliguria, hemoconcentration, leukocytosis, along with intravascular hypovolemia, hyponatremia, and hyperkalemia.[ncbi.nlm.nih.gov]

Workup

  • Further workup revealed markedly elevated serum creatine kinase, abnormal electromyography and edema of her thigh muscles on magnetic resonance imaging. Diagnosis of polymyositis was confirmed by muscle biopsy.[ncbi.nlm.nih.gov]
  • A workup for possible malignancy in this setting appears reasonable.[ncbi.nlm.nih.gov]
Pneumoperitoneum
  • […] complications secondary to the use of mechanical ventilator Cardiovascular: hypotension, reduced cardiac output, cor pulmonale, arrhythmias, pericarditis and acute myocardial infarction Gastrointestinal: haemorrhage, gastric distention, ileus, diarrhoea, pneumoperitoneum[physio-pedia.com]
Mediastinal Mass
  • CT chest with contrast showed a large mediastinal mass. Three different processes coexisted in this patient: simultaneous occurrence of a myasthenia gravis crisis, asthma exacerbation and a component of heroin use.[ncbi.nlm.nih.gov]
Decreased Lung Compliance
  • As examples, acute bronchospasm due to asthma or COPD places an increased resistive load on the respiratory system, acute pulmonary edema decreases lung compliance and thus places an increased elastance load on the system, and in COPD intrinsic PEEP increases[mcgill.ca]

Treatment

  • The cases in this group met the same criteria as those administered the iNO treatment.[ncbi.nlm.nih.gov]
  • Abstract Noninvasive ventilation is an effective treatment for a significant proportion of patients with acute respiratory failure.[ncbi.nlm.nih.gov]
  • You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.[medlineplus.gov]
  • Treatment for respiratory failure depends on whether the condition is acute (short-term) or chronic (ongoing) and its severity. Treatment also depends on the condition's underlying cause. Acute respiratory failure can be a medical emergency.[nhlbi.nih.gov]
  • Another study examines CPAP and medical treatment given at different time intervals, and not supplemental CPAP compared to standard medical treatment alone. It was therefore excluded [ 18 ].[doi.org]

Prognosis

  • Prognosis is poor, particularly after allogeneic transplantation, and literature to guide clinical decision-making is scarce.[ncbi.nlm.nih.gov]
  • Home oxygen therapy (HOT), also known as long-term oxygen therapy, is prescribed to patients with chronic respiratory failure (CRF) due to advanced respiratory diseases, as it has been shown to improve the prognosis of patients with chronic obstructive[ncbi.nlm.nih.gov]
  • BACKGROUND Acquired platythorax, or flattening of the chest with a reduction in the anteroposterior (AP) diameter, is very rare and the prognosis depends on the degree of the deformity, respiratory function, and on any underlying disease.[ncbi.nlm.nih.gov]
  • […] aimed at the underlying lung disease, and may include: Bronchodilator drugs to reverse some airway obstruction Methods to stop smoking Noninvasive positive-pressure ventilation, or mechanical ventilation if needed Oxygen if the blood oxygen level is low Prognosis[hopkinsmedicine.org]
  • Prognosis of Respiratory failure (types I and II) Respiratory failure is a severe condition that is generally terminal unless treated.[healthengine.com.au]

Etiology

  • Despite lung protective ventilation, prone position and neuromuscular blockade, refractory respiratory failure of unknown etiology supervened (ratio of arterial oxygen partial pressure to fractional inspired oxygen 46-130) and ECMO was initiated after[ncbi.nlm.nih.gov]
  • Describe the various etiologies of acute respiratory failure.[mcgill.ca]
  • This unique case highlights periengraftment respiratory failure as a possible patient subgroup that could benefit from ECLS; and illustrates that the distinct etiologies of respiratory failure and the patients' immune status deserve closer consideration[ncbi.nlm.nih.gov]
  • Abstract This article reviews the definition, pathophysiology, etiology, assessment, and management of acute respiratory failure in children.[ncbi.nlm.nih.gov]
  • Regarding etiology, due to high suspicion index, Leptospira serology was performed, coming back positive and meropenem was maintained. The patient ultimately recovered and experience excellent outcome.[ncbi.nlm.nih.gov]

Epidemiology

  • Author information 1 Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Japan. 2 Clinical Research Center, Kobe City Medical Center General Hospital, Japan. 3 Department of Clinical Epidemiology, Hyogo College of Medicine,[ncbi.nlm.nih.gov]
  • A high index of suspicion is needed for an adequate diagnosis of leptospirosis to implement the correct treatment, particularly in the association of respiratory failure, pulmonary hemorrhage, and an epidemiological-related context.[ncbi.nlm.nih.gov]
  • Cleveland, OH, USA. 13 Department of Anesthesia and Intensive Care, Aarhus University Hospital, Aarhus, Denmark. 14 Department of Neuroanesthesiology, Rigshospitalet and University of Copenhagen, Copenhagen, Denmark. 15 Centre for Clinical Research, Epidemiology[ncbi.nlm.nih.gov]
  • The objective of this study was to provide a broad characterization of the epidemiology of ARF among adults hospitalized in the United States using a large nationally representative database.[journalofhospitalmedicine.com]
  • Myasthenia gravis (MG): epidemiological data and prognostic factors. Ann N Y Acad Sci 2003;998413- 423 PubMed Google Scholar Crossref 16. Varelas PNChua HCNatterman J et al.[jamanetwork.com]
Sex distribution
Age distribution

Pathophysiology

  • Abstract This article reviews the definition, pathophysiology, etiology, assessment, and management of acute respiratory failure in children.[ncbi.nlm.nih.gov]
  • We report an unusual case of NMO relapse presenting with rapidly progressive respiratory failure and briefly discuss the possible pathophysiological mechanisms of this potential life-threatening complication of NMO.[ncbi.nlm.nih.gov]
  • Pathophysiological effects of IFN on endothelial vascular cells are discussed.[ncbi.nlm.nih.gov]
  • This review discusses the clinical recognition of primary neuromuscular respiratory failure, its pathophysiology, diagnostic evaluation, and management, focusing on management of respiratory failure in the setting of Guillain-Barré syndrome and myasthenic[ncbi.nlm.nih.gov]
  • Hypoxemic and hypercapnic respiratory failure are described, and the pathophysiological underpinnings of each type are reviewed.[accessmedicine.mhmedical.com]

Prevention

  • This case demonstrates a variety of factors affecting patients, respiratory physicians, occupational physicians, and management teams, which prevents patients from working.[ncbi.nlm.nih.gov]
  • It also can prevent the machine's pressure from injuring your lungs. You'll use the ventilator until you can breathe on your own.[nhlbi.nih.gov]
  • In order to prevent further lung injury, VV-ECMO support was performed for 73 days. Although the patient experienced several complications, patient was successfully managed on VV-ECMO.[ncbi.nlm.nih.gov]
  • Patients are to receive pressure injury prevention management as per the Pressure Injury Prevention Guideline. Pressure Injury Prevention Guideline 30. Patients are to be encouraged to sit out of bed as tolerated.[aci.health.nsw.gov.au]
  • He will require a high flow system in order to prevent significant entrainment of room air and thus dilution of the delivered oxygen.[mcgill.ca]

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