Physical effects The person may experience fatigue, poor balance, slurred words, a weak grip, tripping when walking, or other minor symptoms. Sometimes this stage occurs before a diagnosis is made. [mda.org]

After aprodromal phase (paraesthesias, restlessness, irritaility, fatigue, and myalgias) neurological symptoms will start with paralysis of the lower extremities. The deep tendon reflexes are weak or absent. [cvbd.org]

We have to make a clear distinction between muscle fatigue and muscle weakness. While fatigue is changing over rest, weakness is not. [shortnessofbreath.it]

Patients also report anxiety, insomnia, morning headache, excessive daytime somnolence and fatigue, and poor sleep habits. [emedicine.medscape.com]

if you suspect that there is residual fatigue of the inspiratory muscles, take a day off. keep an IMT diary. [physio-pedia.com]

Abstract Background Oxygenation is impaired in almost all subjects during anesthesia, and hypoxemia for shorter or longer periods is a common finding. [link.springer.com]

Do not wait for ABGs to show hypoxemia or hypercapnia. These are late developing signs that appear only immediately prior to respiratory arrest in MG patients. [myasthenia.org]

Acute respiratory distress syndrome (ARDS) is a lethal syndrome characterized by hypoxemia, bilateral infiltrates and diffuse alveolar damage.(1) Patients presenting with ARDS often require intubation and mechanical ventilation for hypoxemic respiratory [sccm.org]

Both the reduction in strength and endurance of the respiratory muscles are causing alteration of the sleep structure, primarily reducing quantity of rapid eye movement (REM) sleep hypersomnia. [shortnessofbreath.it]

Patients usually are asymptomatic at rest but may experience dyspnea upon exertion and may have a decrease in exercise performance. [12] If the patient has an underlying lung disease, dyspnea may occur at rest. [emedicine.medscape.com]

When symptomatic, the following may be noted : Difficulty breathing when physically active (exertional dyspnea). Reduced endurance. Mild orthopnea – difficulty breathing when lying down. [healthhype.com]

SDB often starts long before exertional dyspnea or orthopnea develop. [clinicaltrials.gov]

Dysfunction of one or both hemidiaphragms is an underdiagnosed cause of dyspnea. [blogs.nejm.org]

Shortness of breath on exertion (dyspnea) Need to sleep sitting up (orthopnea) Retention of carbon dioxide (CO 2 ) morning headaches poor concentration and impaired intellectual function Sleep disturbances not feeling rested in the morning sleepiness [gbppa.org]

pain and coffee-ground emesis. [acgcasereports.gi.org]

In some patients, nonspecific GI symptoms such as heartburn, regurgitation, nausea, and epigastric pain can also develop. [9] In bilateral diaphragmatic paralysis, additional clues to diagnosis include dyspnea further exacerbated in a swimming pool or [emedicine.medscape.com]

When the reactive inflammatory processes are restricted to the meninges, an aseptic meningitis with headache as the chief manifestation results. [clevelandclinicmeded.com]

Severe headache in Guillain-Barré syndrome is rare; an initial episode of a headache, vomiting, fever and back and limb pain is usually followed by paralysis. [guillain-barre.co.uk]

Poor respiration may cause fatigue, fuzzy thinking, headaches, and susceptibility to pneumonia. (Respiratory insufficiency is a leading cause of death in ALS.) Speech, or eating and drinking by mouth, may not be possible. [mda.org]

Patients also report anxiety, insomnia, morning headache, excessive daytime somnolence and fatigue, and poor sleep habits. [emedicine.medscape.com]

Bilateral Rapid shallow breathing Difficulty breathing even at rest Pronounced orthopnea Anxiety Disturbed sleep Fatigue Morning headache Clinical examination reveal absence of or severely dulled breathing sounds, inward movement of the abdomen when inhaling [healthhype.com]

At this time, the differential diagnosis included atypical Guillain-Barre syndrome (GBS), cervical cord compression, and systemic botulism as a complication of endoscopic BTI. [acgcasereports.gi.org]

Causative mechanisms to atelectasis and airway closure seem to be loss of respiratory muscle tone and gas resorption. [link.springer.com]

A: Chest radiographs may reveal elevated hemidiaphragms and basal subsegmental atelectasis. Although chest radiography is a reasonably sensitive tool for detecting unilateral diaphragmatic paralysis (90%), its specificity is unacceptably low (44%). [blogs.nejm.org]

The buildup of mucus can result in atelectasis ((at-uh-LEK-tuh-sis), which is a collapse of all or a portion of the lung. [msktc.org]

On the other hand patients with reduced ability of cough are also at risk of developing pulmonary atelectasis and recidive pulmonary infection. Effective cough can only be produced with a MEP higher than 50–60 cm H 2 0 ( 4 ). [shortnessofbreath.it]

Validation has to be carried out with regard to both daytime hypercapnia and nocturnal retention of carbon dioxide because the latter often represents the earliest manifestation of respiratory muscle weakness. [clinicaltrials.gov]

Do not wait for ABGs to show hypoxemia or hypercapnia. These are late developing signs that appear only immediately prior to respiratory arrest in MG patients. [myasthenia.org]

At the first signs of nocturnal hypercapnia, the patient should be offered NIV therapy rather than waiting until the hypercapnia extends into the daytime period. [shortnessofbreath.it]

Instead, the CO 2 accumulates (called hypercapnia), and thus there is decreased room in the alveoli for oxygen. Hypercapnia and decreased oxygen saturation are the hallmarks of underventilation or hypoventilation. [gbppa.org]

[…] exercised in the following events: history of spontaneous pneumothorax traumatic pneumothorax that has not fully healed burst eardrum or other conditions of the eardrum unstable asthma with abnormally low perception of dyspnoea Precautions Minimise hypercapnia [physio-pedia.com]