All patients received catheter-directed infusion of reteplase (0.5 U/h) in combination with intravenous administration of abciximab (0.25-mg/kg bolus followed by 0.125 microg/kg/min infusion) for 12 hours without systemic heparinization. [ncbi.nlm.nih.gov]

DOSING (Adult): Retavase (Reteplase) is for intravenous administration only. Retavase is administered as a 10 10 U double-bolus injection. Each bolus is administered as an intravenous injection over 2 minutes. [globalrph.com]

Reteplase dosage sponsored Reteplase (Reteplase) is for intravenous administration only. Reteplase is administered as a 10 10 unit double-bolus injection. Two 10 unit bolus injections are required for a complete treatment. [ndrugs.com]

DOSAGE AND ADMINISTRATION Retavase (Reteplase) is for intravenous administration only. Retavase is administered as a 10 10 unit double-bolus injection. Two 10 unit bolus injections are required for a complete treatment. [rxlist.com]

• Cholesterol embolization: Has been reported rarely in patients treated with thrombolytic agents; may present as livedo reticularis, "purple toe" syndrome, acute renal failure, gangrenous digits, hypertension, pancreatitis, myocardial infarction, cerebral [drugs.com]

Clinical features of cholesterol embolism may include livedo reticularis, “purple toe” syndrome, acute renal failure, gangrenous digits, hypertension, pancreatitis, myocardial infarction, cerebral infarction, spinal cord infarction, retinal artery occlusion [rxlist.com]

Clinical features of cholesterol embolism may include livedo reticularis, "purple toe syndrome” syndrome, acute renal failure, gangrenous digits, hypertension, pancreatitis, myocardial infarction, cerebral infarction, spinal cord infarction, retinal artery [wikidoc.org]

cardiac catheterization, angiography, vascular surgery) and/or thrombolytic agents. 1 Clinical features of cholesterol embolism include livedo reticularis, acute renal failure, gangrenous digits/purple toe syndrome, hypertension, pancreatitis, MI, [drugs.com]

Successful catheter recanalization was defined as return of aspiration and infusion function allowing dialysis to be completed at blood flow rates above 300 ml/minute. [ncbi.nlm.nih.gov]

Alternative regimens include instillation of 0.5 - 1 unit reteplase into the catheter to dwell for 20 minutes, after which time the solution is removed by aspiration. [globalrph.com]

A 61-year-old male with a history of severe heparin-induced thrombocytopenia (HIT) type II after aorto-femoral bypass surgery presented to the emergency department within 8 hours of development of substernal chest pain radiating to the left arm. [ncbi.nlm.nih.gov]

³ 180 mm Hg systolic and/or ³ 110 mm Hg diastolic » Organ biopsy, recent Pregnancy » Puncture of noncompressible blood vessel, recent Renal function impairment, severe » Surgery, major, recent » Trauma, recent Infection at or near site of thrombus, [drugs.com]