A case of retrobulbar neuritis which developed in association with intraarterial continuous infusion cisplatin is presented. [ncbi.nlm.nih.gov]

• Cervical Lymphadenopathy

  Three months later he presented with unilateral proptosis and cervical lymphadenopathy. Lymph node biopsy confirmed non-Hodgkin's lymphoma, B-cell type. [ncbi.nlm.nih.gov]

• Scotoma

  It was characterized by decreased visual acuity, mid dilated pupil with sluggish reaction, normal optic disc and central scotoma in Humphrey visual field. Visual acuity improved with systemic Acyclovir and steroids. [ncbi.nlm.nih.gov]

  A cecocentral scotoma may be present and, if bilateral, is almost diagnostic of toxic amblyopia. Etiologic... [mdedge.com]

  Normal 10 Marked constriction Marked constriction Enhancement both nerves Normal 11 Inferior altitudinal Temporal scotoma High signal both nerves, normal L > R 12 Central scotoma Central scotoma High signal both nerves Normal Atrophy both nerves 13 Central [doi.org]

• Visual Impairment

  Some of the symptoms of optic neuritis include: Decreased visual acuity or vision loss Eye pain and impairment of color vision (dyschromatopsia)* *Often, eye pain resolves over a few days as visual loss begins. [chop.edu]

  […] function in patients with ON is usually assessed by visual acuity, and more sensitive measures of visual impairment, such as contrast sensitivity and low-contrast letter acuity. [neurologyindia.com]

  The predominant complication of optic neuritis is visual impairment, and in the worst case, blindess. In children, estimates of residual visual impairment range from 25-33% of patients undergoing all treatments. [clinicaladvisor.com]

  […] prognosis, although approximately 20% of eyes remain visually impaired. [meajo.org]

  Presentation, assessment and diagnosis Usual presentation This is usually a triad of: Visual impairment (of varying severity, usually developing over a period of hours or days, and may typically be exaggerated by a hot bath or shower). [patient.info]

• Unilateral Proptosis

  Three months later he presented with unilateral proptosis and cervical lymphadenopathy. Lymph node biopsy confirmed non-Hodgkin's lymphoma, B-cell type. [ncbi.nlm.nih.gov]

A complete workup including cranial imaging, lumbar puncture, and serologic evaluation in patients presenting with acute neuroretinitis is often necessary because treatments are directed toward the underlying pathogen. [lymeneteurope.org]

Evaluation of ON thus requires a brilliant clinical detail, appropriate laboratory workup and imaging. [neurologyindia.com]

Further workup may include CSF studies of cell count, glucose, protein, VDRL and electrophoresis evaluating for oligoclonal bands. [webeye.ophth.uiowa.edu]

If you see no improvement in your condition despite following these tips and remedies, visit your doctor immediately and avail a further diagnostic workup and treatment if necessary. [stylecraze.com]

See Workup for more detail. [emedicine.medscape.com]

Prompt treatment with systemic antiviral and steroid improve the visual outcome. [ncbi.nlm.nih.gov]

History also revealed that she had taken anti-tubercular treatment for 6 months for tubercular osteomyelitis in the left knee joint at 10 years of age and was fully cured after complete treatment. [jcor.in]

The Optic Neuritis Treatment Trial (ONTT) supports the administration of intravenous methylprednisolone sodium succinate (Solumedrol, 250 mg. every 6 hours) for three days. [decisionmakerplus.net]

Optic Neuritis: Diagnosis, Treatment, and Prognosis Release Date: March 24, 2008 Introduction Optic neuritis is a term used to refer to inflammation of the optic nerve. [arabmedmag.com]

One trial (small and non-randomised, using a different regimen) reported improved vision with immunoglobulin treatment. [ 14 ] Prognosis Visual prognosis The prognosis for vision in ADON is usually good. [ 15 ] The Optic Neuritis Treatment Trial (ONTT [patient.info]

Article Figures/Media Metrics This article reviews the diagnosis, pathophysiological features, and prognosis of ischemic optic neuropathy, a relatively common cause of visual loss in older patients, including visual loss after cardiac surgery. [doi.org]

(Rank 6) 49,562 21,112 15% Type 1 carries poor prognosis, Type 2 can be treated and vision returned Unknown n/a 2% Demyelinating recurrent optic neuritis and non-demyelinating (CRION) [ edit ] The repetition of an idiopathic optic neuritis is considered [en.wikipedia.org]

Prognosis The age of symptom onset (younger patients having a more favorable prognosis) and the causative mutation (patients with MT-ND6 mutations showing highest recovery rates) are factors that determine the disease outcome. [orpha.net]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

[…] of the optic neuritis Identify and exclude any differential diagnosis Determine the monitoring schedule and prescribe a treatment program specific to the etiology Patient History Patients with optic neuritis may present with any of the following abnormal [decisionmakerplus.net]

Neuritis- painful vision loss presentation Epidemiology Age 18-40 yr Mean age 30-35 yr Incidence 6.4/ 100,000 Female (66%) Highest in higher latitudes; lower near equator Prevalence 115/100,000 Race Caucasian > African americans Pathophysiology Possible Etiology [fprmed.com]

Children are more likely to have bilateral visual loss; anterior optic nerve involvement with papillitis; an associated bacterial, viral, or parainfectious etiology; and better visual recovery than adults. [meajo.org]

[…] novelists, and prose writers Literary studies - plays and playwrights Literary studies - poetry and poets Literary theory and cultural studies Shakespeare studies and criticism Media studies Medicine and health Clinical Medicine Dentistry Public Health and Epidemiology [oxfordreference.com]

Introduction Definition an inflammatory demyelinating process affecting the optic nerve Epidemiology incidence most commonly affects women between the ages of 20-40 Etiology multiple sclerosis ethambutol ischemic optic neuropathy ( e.g., diabetes mellitus [medbullets.com]

Scandinavia, United Kingdom, Canada), again, following the epidemiology of MS 3. [radiopaedia.org]

A strong case can be made for "isolated" optic neuritis being a forme fruste of multiple sclerosis, based on similarities between the two in such epidemiologic factors as gender, age, geographic distributions, cerebrospinal fluid changes, histocompatibility [clinicaltrials.gov]

Article Figures/Media Metrics This article reviews the diagnosis, pathophysiological features, and prognosis of ischemic optic neuropathy, a relatively common cause of visual loss in older patients, including visual loss after cardiac surgery. [doi.org]

We postulate different pathophysiologic mechanisms of ON in our three patients: compression of optic nerve due to sphenoid mucocele in the first patient; extension of bacterial infection to the optic nerve in the second patient; and invasion of aspergillosis [link.springer.com]

[…] visual reduction/loss Neuritis- painful vision loss presentation Epidemiology Age 18-40 yr Mean age 30-35 yr Incidence 6.4/ 100,000 Female (66%) Highest in higher latitudes; lower near equator Prevalence 115/100,000 Race Caucasian > African americans Pathophysiology [fprmed.com]

Optic neuritis: Pathophysiology, clinical features, and diagnosis. http://www.uptodate.com/home. Accessed Aug. 19, 2016. Osborne B, et al. Optic neuritis: Prognosis and treatment. http://www.uptodate.com/home. Accessed Aug. 19, 2016. Optic neuritis. [mayoclinic.org]

Pathophysiology The pathology of ADON involves demyelination and axonal loss, probably due to an inflammatory process and a delayed hypersensitivity reaction. Recovery is due to remyelination and compensatory neuronal recruitment. [patient.info]

Biousse reports receiving consulting fees from GenSight Biologics and grant support from Research to Prevent Blindness; and Dr. [doi.org]

Prevention Because the underlying cause of most cases of retrobulbar neuritis is unknown, there is usually no way to prevent it. [drugs.com]

How could such complications be prevented: The first step is to identify patients in whom ethambutol is relatively contraindicated. [ijcasereportsandimages.com]

Prevention Regular annual eye exams are critical to maintaining healthy vision. Early treatment of vision problems can prevent permanent optic nerve damage (atrophy). Resources Books Leitman, Mark. Manual for Eye Examination and Diagnosis. 5th ed. [medical-dictionary.thefreedictionary.com]

With others, there is no treatment, or treatment may only prevent further vision loss. Optic glioma (Medical Encyclopedia) Optic nerve atrophy (Medical Encyclopedia) Optic neuritis (Medical Encyclopedia) [ Read More ] [icdlist.com]