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Retroperitoneal Cancer


Presentation

  • One region it does not present as frequently is the retroperitoneal (RP) space.[cancertherapyadvisor.com]
  • Surgery The best chance for resection with curative intent is at the time of primary presentation.[bccancer.bc.ca]
  • Case presentation A 67-year-old woman received this operation. Preoperative ureteroscopy revealed a papillary neoplasm with a pedicle in the upper calyx of the left kidney.[bmcurol.biomedcentral.com]
  • Eligibility criteria included patients who presented with either retroperitoneal nodal metastases at diagnosis or solitary relapse in the retroperitoneum after initial radical cystectomy.[content.iospress.com]
  • Cancer 2010 Presented by: Joel Sheinfeld, MD, Memorial Sloan Kettering Cancer Center, New York, US Written By: Hanan Goldberg, MD, Urologic Oncology Fellow (SUO), University of Toronto, Princess Margaret Cancer Centre, @GoldbergHanan at the 73rd Canadian[urotoday.com]
Infertility
  • LIVESTRONG Fertility www.livestrong.org/we-can-help/fertility-services 855-744-7777 Provides reproductive information and support to cancer patients and survivors whose medical treatments have risks associated with infertility.[mskcc.org]
Cough
  • Do Breathing and Coughing Exercises Practice taking deep breaths and coughing before your surgery. You will be given an incentive spirometer to help expand your lungs. For more information, read our resource How to Use Your Incentive Spirometer.[mskcc.org]
Sleep Apnea
  • About Sleep Apnea Sleep apnea is a common breathing disorder that causes a person to stop breathing for short periods of time while sleeping. The most common type is obstructive sleep apnea (OSA).[mskcc.org]
Calf Pain
  • A temperature of 101 F (38.3 C) or higher Pain that doesn’t get better with your medication Redness, swelling, or drainage from your incisions that is foul smelling (smells bad) or is pus-like (thick or yellow) Diarrhea or constipation Calf pain Nausea[mskcc.org]
Flushing
Visual Hallucination
  • But on my third day of outpatient chemotherapy, I woke up confused with visual hallucinations and was admitted to the ER. I didn’t work for the next two-and-a-half years. From that day forward for the next year, I was seldom without a caregiver.[mdanderson.org]
Irritability
  • Many people say they felt weepy, sad, worried, nervous, irritable, and angry at one time or another. You may find that you can’t control some of these feelings. If this happens, it’s a good idea to seek emotional support.[mskcc.org]
Retrograde Ejaculation
  • Removing or damaging the nerves is sometimes needed and may cause side effects such as retrograde ejaculation in men. This is a condition where semen is pushed backward into the bladder instead of out of the body.[cancer.ca]
  • In the original full template bilateral RPLND (Figure 1) that was done without nerve sparing, more than 90% of patients had retrograde ejaculation.[urotoday.com]
  • This is called retrograde ejaculation and can impact your fertility (ability to have biological children). For more information, read Retrograde Ejaculation. Your surgeon will try to use nerve sparing techniques if possible.[mskcc.org]
Microscopic Hematuria
  • The most common symptom of pyelo-carcinoma is gross or microscopic hematuria, observed in 70%–80% of the cases [ 5 ], followed by flank pain and a lumbar mass. UTUCs that invade the muscle wall usually have a very poor prognosis.[bmcurol.biomedcentral.com]

Workup

  • The patient should undergo dedicated imaging and workup of the retroperitoneal mass. Surgery The best chance for resection with curative intent is at the time of primary presentation.[bccancer.bc.ca]
  • What the surgeon needs to know Imaging is important in the diagnostic workup of these patients, being required not only for tumor detection, staging, and operative planning, but also for guiding percutaneous or surgical biopsy of these tumors.[ncbi.nlm.nih.gov]
  • Diagnostic Workup The diagnosis and treatment of STS mandates a multidisciplinary approach ideally carried out in reference centers treating a high number of patients annually ( 11 ).[frontiersin.org]

Treatment

  • Retroperitoneal sarcoma cancer treatment in San Diego Retroperitoneal sarcoma cancer treatment in San Diego Scripps MD Anderson Cancer Center physicians use the most advanced treatments, including surgery, radiation and biologic therapy, to eliminate[scripps.org]
  • They were with me through radiation treatments, surgery and my lengthy recovery.[mdanderson.org]
  • Fine needle aspiration should be avoided as it rarely yields diagnostic information and can delay treatment.[bccancer.bc.ca]
  • Radiation and chemotherapy sometimes lower this risk, but given the rarity of this disease, we currently do not have enough information to know if these nonsurgical treatments are truly effective.[curetoday.com]
  • Currently, the standard treatment for renal pelvis carcinoma is radical nephroureterectomy with bladder cuff excision.[bmcurol.biomedcentral.com]

Prognosis

  • They use the stage along with other information about the type and grade of the cancer to make treatment decisions and give a prognosis.[cancer.ca]
  • Retroperitoneal and truncal sarcomas: prognosis depends upon type not location. Ann Surg Oncol. 2007;14:1114–22. 9. Bilimoria KY, Stewart AK, Winchester DP, et al.[nature.com]
  • UTUCs that invade the muscle wall usually have a very poor prognosis. The 5-year specific survival is less than 50% for pT2/pT3 tumors and less than 10% for pT4 tumors [ 6 ].[bmcurol.biomedcentral.com]
  • Treatment and prognosis Prognosis depends on the histological type of a tumor and the potential for resection.[radiopaedia.org]
  • The study by Dodd et al. revealed that, while patients with regional adenopathy had improved outcomes with post-chemotherapy surgery, those with distant lymph nodal disease had poorer prognosis despite surgical resection [ 8 ].[content.iospress.com]

Etiology

  • Andrews noted that trauma was apparently not of etiologic importance. In our series only one patient gave a history of trauma. Copyright 1940 American Association for Cancer Research[cancerres.aacrjournals.org]
  • […] neoplasms arise from outside the major organs, and are divided according to histological types: mesenchymal origin : skeletal muscle, fat, peripheral nerve, vessels, fibrous tissue extragonadal germ cell tumors primary retroperitoneal adenocarcinoma Etiology[radiopaedia.org]
  • The doctors at his local hospital were unable to find the etiology of his postoperative pain. The patient was referred to a different hospital for consultation.[jpalliativecare.com]

Epidemiology

  • Soft tissue sarcoma across the age spectrum: a population-based study from the Surveillance Epidemiology and End Results database. Pediatr Blood Cancer. 2011 Dec;57(6):943–9. Karadayi K, Yildiz C, Karakus S, Kurt A, Bozkurt B, Soylu S et al.[karger.com]
  • The aim of the present study was to report a giant retroperitoneal liposarcoma, and to discuss the epidemiology, histopathology, imaging characteristics and the management of retroperitoneal liposarcoma.[spandidos-publications.com]
  • .: “Epidemiological features of testicular teratoma in a prepubertal population”. J. Urol., 158: 1191, 1997. [ Links ] 21.[scielo.isciii.es]
  • Computed tomographies and cancer risk in children: a literature overview of CT practices, risk estimations and an epidemiologic cohort study proposal.[frontiersin.org]
Sex distribution
Age distribution

Prevention

  • The surgeon will try to avoid removing the nerves and prevent damage to the nerves in the back of the abdomen (called a nerve-sparing RPLND).[cancer.ca]
  • This will help your lungs expand, which prevents pneumonia. For more information, read our resource How to Use Your Incentive Spirometer. Read our resource Call! Don't Fall![mskcc.org]
  • Your surgeon will use a variety of intraoperative techniques to prevent lymphatic leak.[hopkinsmedicine.org]
  • “We are trying this approach to prevent the gastrointestinal toxicity found in previous trials of omni-directional brachytherapy implants.” Howell said.[foxchase.org]
  • In this case, to prevent cancer spillage or seeding, we suggest guaranteeing the resection range be sufficient and avoiding touching and squeezing the tumor.[bmcurol.biomedcentral.com]

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