Surgery The best chance for resection with curative intent is at the time of primary presentation. [bccancer.bc.ca]

Le et al. published their analysis on tumor regression in ovarian cancer, building a composite score of points for “not/minimally present”, “moderately present” or “extensively present” for histological markers of necrosis, fibrosis, macrophage infiltration [ar.iiarjournals.org]

One region it does not present as frequently is the retroperitoneal (RP) space. [cancertherapyadvisor.com]

The most frequent presenting symptom is pain in the lower back, flank or abdomen, which tends to increase over time[12]. Other common symptoms include weight loss, anorexia, testicular pain, edema, and gross hematuria[2]. [ncbi.nlm.nih.gov]

Other common presentations of retroperitoneal fibrosis are nonspecific, including lower back and flank pain, malaise, anorexia, weight loss, fevers, nausea, and vomiting.7 Gastric cancers can present with additional nonspecific symptoms such as abdominal [facs.org]

Conclusion We recommend timely workup of patients who present with clinical symptoms concerning for malignancy and RPF. [facs.org]

The patient should undergo dedicated imaging and workup of the retroperitoneal mass. Surgery The best chance for resection with curative intent is at the time of primary presentation. [bccancer.bc.ca]

What the surgeon needs to know Imaging is important in the diagnostic workup of these patients, being required not only for tumor detection, staging, and operative planning, but also for guiding percutaneous or surgical biopsy of these tumors. [ncbi.nlm.nih.gov]

Diagnostic Workup The diagnosis and treatment of STS mandates a multidisciplinary approach ideally carried out in reference centers treating a high number of patients annually ( 11 ). [frontiersin.org]

The multivariate analysis also showed that treatment response was a significant factor for OS and the N category <2, treatment response and interval ≤12 months were significant factors for PFS. [dovepress.com]

Fine needle aspiration should be avoided as it rarely yields diagnostic information and can delay treatment. [bccancer.bc.ca]

So far, however, systemic chemotherapy has a limited role in the treatment of RPS. Another treatment modality that is gaining traction is neoadjuvant chemotherapy as a radiosensitizer in conjunction with radiation therapy. [cancernetwork.com]

“We have options here that go beyond standard treatments.” [foxchase.org]

Treatment for secondary cancer may involve surgery, radiotherapy or chemotherapy as appropriate. Your treatment will be assessed on an individual basis. [sarcoma.org.uk]

Burghardt et al. [16] analyzed stage III ovarian cancer patients, also found a superior prognosis of lymphadenectomy. [bmccancer.biomedcentral.com]

Usually retroperitoneal fibrosis secondary to malignant disease is associated with a dismal prognosis. [ncbi.nlm.nih.gov]

An important part of the diagnosis-identification of the histologic subtype-depends on pathology; identifying the histologic subtype is important because this can affect prognosis and treatment options. [cancernetwork.com]

Treatment and prognosis Prognosis depends on the histological type of a tumor and the potential for resection. [radiopaedia.org]

They use the stage along with other information about the type and grade of the cancer to make treatment decisions and give a prognosis. [cancer.ca]

Andrews noted that trauma was apparently not of etiologic importance. In our series only one patient gave a history of trauma. Copyright © 1940 American Association for Cancer Research [cancerres.aacrjournals.org]

[…] neoplasms arise from outside the major organs, and are divided according to histological types: mesenchymal origin : skeletal muscle, fat, peripheral nerve, vessels, fibrous tissue extragonadal germ cell tumors primary retroperitoneal adenocarcinoma Etiology [radiopaedia.org]

However, its etiology and pathobiology remain obscure. This mechanism is different in carconoid tumors, which may lead to retroperitoneal fibrosis without the presence of metastasis probably through a serotonin-mediated mechanism[14]. [ncbi.nlm.nih.gov]

Because of its rarity, the incidence, etiology and clinical management of the less common/rare site endometriosis-associated cancer is poorly understood. [hindawi.com]

This etiology of ureteral obstruction is distinct from that caused by external compression from pelvic peritoneal disease due to gastric cancer. [facs.org]

Gastric cancer: epidemiology and risk factors. Gastroenterol Clin North Am. 2013;42(2):219-240. doi:10.1016/j.gtc.2013.01.003 Mansfield PF. Clinical features, diagnosis, and staging of gastric cancer. UpToDate. 2020. [facs.org]

Soft tissue sarcoma across the age spectrum: a population-based study from the Surveillance Epidemiology and End Results database. Pediatr Blood Cancer. 2011 Dec;57(6):943–9. Karadayi K, Yildiz C, Karakus S, Kurt A, Bozkurt B, Soylu S et al. [karger.com]

The aim of the present study was to report a giant retroperitoneal liposarcoma, and to discuss the epidemiology, histopathology, imaging characteristics and the management of retroperitoneal liposarcoma. [spandidos-publications.com]

“Epidemiological features of testicular teratoma in a prepubertal population”. J. Urol., 158: 1191, 1997. [ Links ] 21. [scielo.isciii.es]

Table 1 Epidemiological and clinicopathological characteristics of patients with and without metastasis to lymph nodes. Lymphadenectomy of PALN was performed in 475/836 (56.8%) patients of staging surgeries. [frontiersin.org]

This case prompts interesting issue with regard to the pathophysiology and clinical presentation of extra-ovarian endometriosis. [hindawi.com]

“We are trying this approach to prevent the gastrointestinal toxicity found in previous trials of omni-directional brachytherapy implants.” Howell said. [foxchase.org]

Nerve-sparing surgery techniques can prevent retrograde ejaculation in most men who have this surgery. footnote 1 Try to find an experienced surgeon and a medical center where many surgeries are done for your kind of cancer. [cigna.com]

The surgeon will try to avoid removing the nerves and prevent damage to the nerves in the back of the abdomen (called a nerve-sparing RPLND). [cancer.ca]