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Retrovirus-Associated Myelopathy

Presentation

In the present study, we investigated the possible role of phosphorylation in the regulation of p13 function. [research.unipd.it]

The current understanding of HERVs, and specifically the investigations of HERV activation and expression in MS are the major subjects of this review, which also proposes to synergise the herpes and HERV findings, and presents several possible pathogenic [pubmed.ncbi.nlm.nih.gov]

HTLV-I-associated infective dermatitis: past, present, and future. J Acquir Immune Defic Syndr Hum Retrovirol 1996; 13:S46–9. CrossRef PubMed Google Scholar La Grenade L, Manns A, Fletcher V et al. [link.springer.com]

Treatment

Safety of long-term treatment of HAM/TSP patients with valproic acid. Blood. 2011; 118 (24): 6306-09. McInnes IB, Gracie JA. Interleukin-15: a new cytokine target for the treatment of inflammatory diseases. Curr Opin Pharmacol. 2004; 4 (4): 392-97. [revistas.unicauca.edu.co]

Immunopathogenesis and treatment of the myelopathy associated to the HTLV-I virus. 2009;48:147-155 [cited 2022 Feb 21]. doi: 10.33588/rn.4803.2008650. Enose-Akahata Y, Billioux BJ, Azodi S, Dwyer J, Vellucci A, Ngouth N, et al. [revistadelnacional.com.py]

Afonso PV, Mekaouche M, Mortreux F, et al (2010) Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors. Blood 116 (19):3802–3808 [Epub 2010 Jun 29] PubMed Article CAS Google Scholar 2. [link.springer.com]

Mogamulizumab for the treatment of adult T-cell leukemia/lymphoma. Clin Lymphoma Myeloma Leuk. 2019;19(6):326-31. doi: 10.1016/j.clml.2019.03.004. [ Links ] 39. Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, et al. [scielo.org.co]

Epidemiology

Epidemiology of Tropical Spastic Paraparesis in Colombia and Associated HTLV-I Infection. Ann Neurol. 1988;23 Suppl: S161-65. Trujillo JM, Concha M, Muñoz A, Bergonzoli G, Mora C, Borrero I. [revistas.unicauca.edu.co]

Human T-lymphotropic virus type I: Virology, pathogenesis, and epidemiology. En: Bloom A (editor), UpToDate; 2020. [ Links ] 5. Matutes E. Adult T-cell leukaemia/lymphoma. [scielo.org.co]

Tropical spastic paraparesis and HTLV-1 associated myelopathy: clinical, epidemiological, virological and therapeutic aspects. Rev Neurol (Paris) [Internet]. 2012 [cited 2022 Feb 22];168(3):257–69. doi: 10.1016/j.neurol.2011.12.006. [revistadelnacional.com.py]

Proietti FA, Carneiro-Proietti AB, Catalan-Soares BC, Murphy EL (2005) Global epidemiology of HTLV-1 infection and associated diseases. Oncogene 24(39):6058–6068 PubMed Article CAS Google Scholar 29. [link.springer.com]

Prevention

Goncalves DU, Proietti FA, Ribas JG, et al (2010) Epidemiology, treatment, and prevention of human T-cell leukemia virus type 1-associated diseases. Clin Microbiol Rev 23(3):577–589 PubMed Article CAS Google Scholar 11. [link.springer.com]

European Centre for Disease Prevention and Control. Geographical distribution of areas with a high prevalence of HTLV-1 infection. Estocolmo: ECDC; 2015. [ Links ] 9. Borda M, Svibel G, Biglione M, Berini C. [scielo.org.co]

Anti-Tac (daclizumab-Zenapax) in the treatment of leukemia, autoimmune diseases and in the prevention of allograft rejection: a 25-year personal odyssey, J Clin Immunol. 2007; 27 (1): 1-18. [revistas.unicauca.edu.co]

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