Neonatal cardiac rhabdomyoma: An unusual presentation. J Clin Neonatol 2015;4:123-5 Introduction Intracardiac tumors are very rarely seen in neonates and infants. [jcnonweb.com]

Clinical presentation: Clinical profile varies from still-birth to intrauterine myocardial infarct (due to coronary artery compression). [histopathology-india.net]

The patient presented with a systolic murmur (graded 3/6) with a palpable thrill, no cyanosis, and no edema. [jtd.amegroups.com]

In more than half of the cases, it spontaneously remits after weaning. 5 We present the case of a patient with an echocardiographic diagnosis of suspected multiple rhabdomyomas with spontaneous, complete early remission. [revespcardiol.org]

Occasionally, they may present with left ventricular outflow tract obstruction or refractory arrhythmias. It is a hamartomatous lesion consisting of cardiac muscle tissue (derived from embryonal myoblasts). [radiopaedia.org]

• Congestive Heart Failure

  Complications development of cardiac arrhythmias intracavitary growth may cause ventricular outflow tract obstruction valvular compromise disruption of intracardiac blood flows leading to congestive heart failure and hydrops For the in utero sonographic [radiopaedia.org]

  Congestive heart failure and a low cardiac output can occur when the tumor extensively involves the myocardium or the ventricular papillary muscles. Cyanosis and decreased peripheral pulses can result. [emedicine.medscape.com]

  Reference: Artificial cardiac Pacemaker Sonography of the heart (echocardiography) was done in this patient of congestive cardiac failure (CCF) or congestive heart failure (CHF). [ultrasound-images.com]

  Clinical symptoms in the neonate include severe congestive heart failure and cyanosis. 52, 54, 56, 63, 64 Significant pericardial effusions have also been associated with fibromas. 29 Myxoma Cardiac myxomas are the most common primary cardiac tumor in [radiologykey.com]

  Complications due to Cardiac Rhabdomyosarcoma could include: Congestive heart failure, depending on the location of the tumor in the heart Increased risk for thromboembolism (blood clot obstructing a blood vessel) Metastasis of the tumor to other sites [dovemed.com]

• Soft Tissue Mass

  Intracavitary soft tissue mass arising from the interventricular septum. Intracavitary soft tissue mass arising from the interventricular septum. Nodular mass invading the left atrial wall and mitral valve. Left atrium. Variable population. [radcharts.org]

• Regurgitation

  The pulmonary valve functioned well with mild regurgitation and no residual tumor was detected by TTE at 3-month follow-up. Discussion Rhabdomyomas are frequently located in the left ventricle ( 7 ) and may cause sudden death in infants ( 8 ). [jtd.amegroups.com]

  There was also evidence of tricuspid regurgitation (image on right- Color Doppler). The right ventricle and the right atrium appear enlarged. These ultrasound images suggest Ebstein anomaly with tricuspid regurgitation. Both images courtesy of Dr. [ultrasound-images.com]

  If the valvular lesion is severe, it is essential for the proper maintenance of the circulation that certain changes should take place in the heart to compensate for or neutralize the effects of the regurgitation or obstruction, as the case may be. [thefullwiki.org]

• Heart Disease

  Some people are born with heart disease. [icdlist.com]

  Because tumors in the heart can mimic other heart diseases, they are difficult to diagnose accurately. [cedars-sinai.edu]

  Volodaver Z, Neufeld HN, Edwards JE: Coronary Arterial Variations in the Normal Heart and in Congenital Heart Disease. New York, Academic Press, 1975. 4. [sonoworld.com]

  […] with sudden cardiac death ( Pediatr Dev Pathol 2007;10:129 ) Not a true neoplasm, but a hamartoma or malformation due to mutation in TSC1 and TSC2 genes 50% of patients have tuberous sclerosis; sporadic cases are occasionally associated with congenital heart [pathologyoutlines.com]

  Disease Congenital heart disease, table Heart, probe patent foramen ovale, and paradoxical embolus, gross Heart, atrial septal defect, gross Heart, atrial septal defect, Eisenmenger's complex, gross Heart, ventricular septal defect, gross Heart, atrial [library.med.utah.edu]

• Systolic Murmur

  A girl born on December 11, 1964, had a precordial systolic murmur at 3. .. [nejm.org]

  The patient presented with a systolic murmur (graded 3/6) with a palpable thrill, no cyanosis, and no edema. [jtd.amegroups.com]

• Cardiomegaly

  Cardiac rhabdomyoma is frequently multiple and asymptomatic, but the tumour may cause cardiomegaly, heart failure by causing outflow obstruction, arrhythmias, thromboembolic disease or sudden unexpected death. [histopathology-india.net]

• Pericardial Disorder

  They can cause valvular or inflow-outflow tract obstruction, thromboembolism, arrhythmias, or pericardial disorders. Diagnosis is by echocardiography and frequently cardiac MRI. [msdmanuals.com]

• Cutaneous Manifestation

  Other late-occurring cutaneous manifestations of tuberous sclerosis include subcutaneous nodules, subungual fibromas, linear epidermal nevi, and café-au-lait pigmentation. Seizures during the neonatal period are not infrequent. [emedicine.medscape.com]

• Subcutaneous Nodule

  Other late-occurring cutaneous manifestations of tuberous sclerosis include subcutaneous nodules, subungual fibromas, linear epidermal nevi, and café-au-lait pigmentation. Seizures during the neonatal period are not infrequent. [emedicine.medscape.com]

• Macula

  […] lines Forehead plaque 7 Lobulated mass in LV West Syndrome Not performed Hypomelanotic maculae No Negative 8 Multiple rhabdomyomas Partial seizures Cortical tubers Hypomelanotic maculae Retinal hamartoma Positive Lennox-Gastaut syndrome Subependymal [bmccardiovascdisord.biomedcentral.com]

• Ventricular Hypertrophy

  hypertrophy, gross Heart, hypertrophy with hypertension, gross Miscellaneous Cardiac Diseases Peripheral coronary artery with sclerosis, microscopic Heart with pacemaker, gross Porcine valve bioprosthesis, gross Mechanical valve prosthesis, tilting disk [library.med.utah.edu]

• Ischemic Changes

  Irreversible ischemic changes occur during fatal episodes of paroxysmal atrial tachycardia(14). [conganat.org]

MRI T1 : isointense to adjacent myocardium T2: hyperintense to adjacent myocardium Treatment and prognosis In most cases, no treatment is required, and these lesions regress spontaneously. [radiopaedia.org]

Patients with inoperable cardiac rhabdomyomas and with symptoms may be candidates for everolimus treatment. [pediatrics.aappublications.org]

Treatment of benign tumors is usually surgical resection; tumors may recur. Treatment of metastatic cancer depends on tumor type and origin; prognosis is generally poor. Primary cardiac tumors are found in 1/2000 people at autopsy. [msdmanuals.com]

Michler RE, Goldstein DJ: Treatment of cardiac tumors by orthotopic cardiac transplantation. Semin Oncol 1997;24:534-539 81. [fac.org.ar]

Without treatment, patients have a life expectancy of only a few months ( 7, 16, 17 ). [aerzteblatt.de]

The overall prognosis is dependent on the number, size and location of the lesions as well as the presence or absence of associated anomalies. [radiopaedia.org]

It should also be noted that symptomatic patients generally have a poorer prognosis than those who are asymptomatic [ 5 ]. A review of all papers on cardiac rhabdomyomas published up to 1990 is available [ 11 ]. [em-consulte.com]

Treatment of metastatic cancer depends on tumor type and origin; prognosis is generally poor. Primary cardiac tumors are found in 1/2000 people at autopsy. Metastatic tumors are 30 to 40 times more common. [msdmanuals.com]

Rhabdomyoma should be differentiated from other tumors and cardiac foci that have a very different prognosis. The editor of Images in Cardiovascular Medicine is Hugh A. [circ.ahajournals.org]

(Etiology) The exact cause and mechanism of formation of Cardiac Rhabdomyosarcoma is unknown. [dovemed.com]

III) Cardiomyopathy The clinical and pathological alterations described have benn frequently described as a CARDIOMYOPATHY, the etiology of which is unclear(3,13). [conganat.org]

[…] atrium and ventricle Figure 4 Positron emission tomography/computed tomography of nodular ecurrent sarcoma Figure 5 Explanted heart after ex-situ resection of a sarcoma and implantation of a mitral valve before cardiac reimplantation Benign tumors Myxoma Epidemiology [aerzteblatt.de]

Criterion for fetal primary spongiform Cardiomyopathy: restrictive pathophysiology. Obstet Gynecol 2002 May; 99 (5 pt 2); 882-5. 7. Stamm E and Drose J. The Fetal Heart, in Rumack C, Wilson S, Charboneau J. Diagnostic Ultrasound. 2nd edition. [sonoworld.com]

In the Anura (frogs and toads) the whole ventricle is filled with a spongy network which prevents the arterial and venous blood from the two auricles mixing to any great extent. [thefullwiki.org]