In the present study, five of the eight cases presented with cutaneous lesions as sessile growth and one presented with both sessile and pedunculated growth, of which two were clinically diagnosed as possible neurofibroma. [njlm.net]

The present study describes, for the first time, the clinical and the ultrastructural findings of a rare case presented with concurrent conjunctival infection of Rhinosporidium seeberi and a papovavirus. [ncbi.nlm.nih.gov]

[…] of the lacrimal sac presenting as IOID. [journals.lww.com]

We use cookies in a very limited number of scenarios that are all present to help the users to have an easier experience. List of cookies present on a website managed by BioloMICS: 1. [mycobank.org]

• Swelling

  […] of IOID with recurrent pain and swelling. [journals.lww.com]

  He presented with a diffuse left medial infraorbital swelling for a period of 14 months. He also complained of intermittent epiphora. [sciepub.com]

  A 13 yr old female presented with a history of slow-growing right-sided swelling in the nose along with unilateral nasal obstruction, bleeding, and discharge. On examination, the swelling was friable, polypoidal with a strawberry appearance. [microbiologyjournal.org]

• Inflammation

  It typically causes chronic nongranulomatous inflammation. Various stages of the R seeberi life cycle can be seen in the affected tissue. [ncbi.nlm.nih.gov]

  Figure 1: (a and b) Microphotograph showing epithelium of lacrimal sac with multiple sporangia and sporocysts of rhinosporidiosis with chronic inflammation. [journals.lww.com]

• Weakness

  To progress, one needs to identify the areas of one's weakness and to strengthen them. It is well said that "happy beginning is half done" and it fits perfectly with JCDR. [jcdr.net]

  The bilamellar cell wall has one weak spot known as the operculum. Maturation of spores occur in both centrifugal and centripetal fashion. This spot does not have chitinous lining, but is lined only by a cellulose wall. [drtbalu.com]

  The bilamellar cell wall has one weak spot known as the operculum. This spot does not have chitinous lining, but is lined only by a cellulose wall. Maturation of spores occur in both centrifugal and centripetal fashion. [slideshare.net]

• Pharyngitis

  Anti-rhinosporidial antiseptics that could be used in surgery on rhinosporidial patients include povidone-iodine in nasal packs for nasal and naso-pharyngeal surgery, chlorhexidine and cetrimide-chlorhexidine on the skin, while povidone-iodine and silver [ncbi.nlm.nih.gov]

  Pt had history of recurrent nasal & pharyngeal rhinosporidiosis for which he had been operated for 59 times since the age of 10.  In 1992 he got lateral rhinotomy, wide base diathermy coagulation done for nasal & pharyngeal rhinosporidiosis.  In 1993 [slideshare.net]

  The erythematous polypoidal mass was 5 x 4 cm and was extending through the nasopharynx and hanging into the oropharynx up to the level of the posterior one-third of the tongue along the posterior pharyngeal wall [Figure 2]. [atmph.org]

  Involvement of site other than naso-pharyngeal mucosa, especially skin, is very rare. Males acquire the disease more commonly compared to females and it is usually seen between the second and fourth decades of life (2). [njlm.net]

• Skin Lesion

  CONCLUSION Disseminated cutaneous rhinosporidiosis may present with skin lesions masquerading as several common skin diseases, which leads to diagnostic dilemmas and social stigma for patients. [njlm.net]

  The lesion produces reddish polypoidal, bulky, friable mucosal masses in the nasal cavity and nasopharynx. Less frequently the infection involves the conjunctiva, mouth, larynx, genitalia and skin. [histopathology-india.net]

  Karunarathnae accounted for satellite lesions in skin and conjunctival mucosa as a result of auto inoculation. Rhinosporidiosis affecting distant sites could be accounted for only through haematogenous spread. [drtbalu.com]

  In a study of 462 cases of rhinosporidiosis in Chhattisgarh, India, an endemic area, the nose and nasopharynx were the most common sites (81.1%), followed by ocular tissue (14.2%).6) Rarely, skin lesions are the predominant manifestation of the disease [kjorl.org]

• Erythema

  There was fullness of the right lower lid with erythema, induration, and tenderness. Regurgitation on pressure on the lacrimal sac (ROPLAS) was negative and syringing showed the lacrimal drainage system to be bilaterally patent. [journals.lww.com]

• Distractibility

  This serves as a distraction. 5. Immune deviation 6. Binding of host immunoglobins Treatment: Surgery is the treatment of choice. Rhinosporidial mass can be removed intranasally, the only problem being bleeding. [drtbalu.com]

  Immune distraction.  5. Immune deviation.  6. Binding of host immunoglobins.  22. Nasal  Nasopharyngeal  Mixed  Bizzarre (ocular and genital)  Malignant rhinosporidiosis (cutaneous rhinosporidiosis)  23. [slideshare.net]

• Confusion

  Antigenic variation - Rhinosporidial spores express varying antigens thereby confusing the whole immune system of the body. 3. Immune suppression - ? possible release of immuno suppressor agents 4. [drtbalu.com]

  […] extruded.3) The various developmental stages of sporangia can be readily identified by using special fungus stains, such as GMS, Gridley's, and PAS stains, although the stages can also be identified with hematoxylin and eosin stain.3) The endospores may be confused [kjorl.org]

  Antigenic variation - Rhinosporidial spores express varying antigens thereby confusing the whole immune system of the body.  21. 3. Immune suppression - possible release of immuno suppressor agents.  4. Immune distraction.  5. [slideshare.net]

• Irritability

  The use of 2% silver nitrate to cauterize the base of the polyp has been recommended. [30] On account of the irritant effect of this agent, povidone-iodine that is also effective against endospores, may be preferred when diluted with aqueous benzalkonium [doi.org]

• Agitation

  Dye tests The Evan's Blue (EvB) dye test Approximately 50 µL of a 0.2% of EvB in PBS was added to the thrice washed pellet of endospores, the mixture was agitated by side tapping of the tube and then incubated at RT for 45 minutes. [doi.org]

• Rabies

  […] rhinosporidiosis has been documented, while the putative source of the pathogen is thought to be natural ground waters, disinfection of laboratories, wards, theatre and instruments, yet remains mandatory; "…emotive connotations for hospital staff…" that occur with rabies [doi.org]

• Coccidioides Immitis

  […] resemble those of Coccidioides immitis. [jomfp.in]

  Common fungi causing conjunctivitis are: Candida albicans, Candida parapsilosis, Candida tropicalis, Paracoccidioides brasiliensis, Coccidioides immitis, Blastomyces dermatitidis, Rhinosporidium seeberi, Sporothrix schenckii, etc. [medical-dictionary.thefreedictionary.com]

  Its morphologic characteristics resemble those of Coccidioides immitis: both organisms have mature stages that consist of large, thick-walled, spherical structures containing smaller daughter cells (endospores). [medscape.com]

• Candida

  Common fungi causing conjunctivitis are: Candida albicans, Candida parapsilosis, Candida tropicalis, Paracoccidioides brasiliensis, Coccidioides immitis, Blastomyces dermatitidis, Rhinosporidium seeberi, Sporothrix schenckii, etc. [medical-dictionary.thefreedictionary.com]

  Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter Menadione-augmented 3 (4, 5 dimethyl-2-Thiazolyl)-2, 5-diphenyl-2H-tetrazolium bromide assay. J Clin Microbiol 1995 ; 33:661-7. 13. [doi.org]

Local surgical excision is the mainstay of treatment which was successfully done in this case. [microbiologyjournal.org]

Surgical excision, may recur No effective medical treatment Gross description Hyperplastic, polypoid, red, granular masses of nasal cavity Yellow pinhead spots represent mature sporangia Superficial mucus is common Microscopic (histologic) description [pathologyoutlines.com]

Treatment is essentially surgical excision of the mass. [web.archive.org]

Its mainstay of treatment is surgery. [parjournal.net]

It is also known to arrest the maturation of sporangia and promote fibrosis in stroma Prognosis [web.archive.org]

Prognosis is excellent, but recurrence is not unusual Keywords Computed tomography scan, lacrimal sac, Rhinosporidium seeberi, rhinosporidiosis Introduction Rhinosporidiosis is a chronic granulomatous disease affecting the mucous membrane primarily. [parjournal.net]

It is the only method for etiologic diagnosis of some organisms such as Pneumocystis jiroveci (formerly Pneumocystis carinii), Loboa loboi, and Rhinosporidium seeberi. [medical-dictionary.thefreedictionary.com]

The association of a specific etiologic agent with certain types of nasal polyps was demonstrated independently by Seeber1 and by O'Kinealy.2 The agent in question is Rhinosporidium seeberi, or Rhinosporidium kinealyi. [jamanetwork.com]

The etiologic agent, Rhinosporidium seeberi, commonly produces granulomatous inflammation of the upper respiratory mucosa. Most reported ocular infections have occurred in hot, dry climatic regions. [ncbi.nlm.nih.gov]

Epidemiology Etiological Agent The etiology of Rhinosporidiosis is uncertain and varied. Various theories are Fungi called Rhinosporidium seeberi. Hoever this organism has not been grown in lab-cultures and does not fully satisfy Kochs postulates. [web.archive.org]

Epidemiological survey of rhinosporidiosis in Kanyakumari district in Tamil Nadu, India. Mycopathologia 1988; 101: 177. [link.springer.com]

The stimulation of R. seeberi's sporangia by water supports the epidemiological studies that had linked this pathogen with wet environments. It also explains, in part, its affinities for mucous membranes in infected hosts. [ncbi.nlm.nih.gov]

[Journal Article] JF J Fungi (Basel) 2018 Jun 25; 4(3) Arsenijević VA, Denning DW For the first time, we aimed to estimate the burden of serious fungal infections or diseases (SFD) and highlight national epidemiological features in Serbia. [unboundmedicine.com]

The epidemiology, ecology, clinical aspects, diagnosis, pathology, and management of the patient are then explained. The second section is concerned with animal disease. [amazon.com]

These findings are applicable in both clinical and laboratory practice, while the basic advances have implications in further work on experimental pathogenicity, the biology of R. seeberi, and on the epidemiology and pathogenesis of rhinosporidiosis. [doi.org]

Clinical features, pathophysiology, and management of lacrimal sac rhinosporidiosis have been discussed. [ncbi.nlm.nih.gov]

Clinical features, pathophysiology, and management of lacrimal sac rhinosporidiosis have been discussed. Keywords: Dacryocystectomy, oculosporidiosis, Rhinosporidium How to cite this article: Mukherjee B, Mohan A, Sumathi V, Biswas J. [ijo.in]

Pathophysiology Local infection from exposure to the organism appears to be implicated in the pathogenesis of R. seeberi, but thus far, it has not been possible to intentionally infect an animal model (2). [webeye.ophth.uiowa.edu]

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Emerging Infectious Diseases. 2000;6(3) © 2000 Centers for Disease Control and Prevention (CDC) Cite this: Rhinosporidium seeberi: A Human Pathogen From a Novel Group of Aquatic Protistan Parasites - Medscape - May 01, 2000. [medscape.com]

A need also exists clinically for the use of topical antiseptics to prevent recurrence of the disease due to the occurrence of 'auto-inoculation' of endospores [7] that will inevitably contaminate adjacent mucosal surfaces during surgery, with the consequent [doi.org]

J Clin Microbiol. 1999 Sep; 37 (9):2750–2754. [ PMC free article ] [ PubMed ] [ Google Scholar ] Articles from Emerging Infectious Diseases are provided here courtesy of Centers for Disease Control and Prevention [ncbi.nlm.nih.gov]