METHODS: To compare the presentation and outcomes of patients with rhinovirus and EV-D68, 103 GenMark rhinovirus positive nasopharyngeal swabs from hospitalized children were retested for EV-D68. [ncbi.nlm.nih.gov]

• Falling

  Weekly nasal mucus samples were analyzed for RVs, and respiratory symptoms and asthma exacerbations were recorded over a 90-day period during the fall seasons of 2012 or 2013. [ncbi.nlm.nih.gov]

  There is a surge in exacerbations in the fall, which is likely multifactorial, including seasonal viral and allergen exposures. [immunology.sciencemag.org]

• Inflammation

  BACKGROUND: Rhinovirus (RV) infection in asthma induces varying degrees of airway inflammation (e.g. neutrophils), but the underlying mechanisms remain unclear. [ncbi.nlm.nih.gov]

• Recurrent Infection

  Antibodies in Nose Recurrent infections with antigenic variants, may be 2-3 attacks a year. Dr.T.V.Rao MD 24 41. Prevention and Control No specific treatment. Vaccines are unsuccessful. [slideshare.net]

  This is in accordance with previous studies reporting high rates of recurrent infections caused by different rhinovirus types, and limited duration of virus shedding in immunocompetent individuals, rather than prolonged carriage of the same rhinovirus [pediatrics.aappublications.org]

• Anemia

  […] cases in a group with patients who presented with a risk factor and a group of patients who did not present with risk factors, and according to the severity of symptoms in each group. a Early age exclusively. b Smoking during pregnancy, atopic disease, anemia [pediatrics.aappublications.org]

• Lymphadenopathy

  […] the diagnosis based on clinical presentation diagnosis of exclusion in patients with immunosuppression Differential Streptococcal pharyngitis distinguishing factor typically presents with erythematous pharynx, tonsillar exudates, petechiae, and tender lymphadenopathy [medbullets.com]

• Common Cold

  Rhinovirus A virus that infects the upper respiratory system and causes the common cold. [medical-dictionary.thefreedictionary.com]

  […] has been found 18. one of the most common illnesses to man 19. 35 to 50% of the total number of common colds 20. [slideshare.net]

  […] ago from individuals with common cold symptoms. [academic.oup.com]

  Introduction Rhinovirus infections are the most frequent cause of common cold illnesses. [doi.org]

  Rhinovirus C, along with rhinoviruses A and B, is a leading cause of common colds. [nih.gov]

• Nasal Congestion

  Infection is characterized by dry scratchy throat, nasal congestion, malaise, and headache. Fever is minimal. Nasal discharge lasts 2 or 3 days. Children may also develop a cough. Type-specific antibodies may last for 2 to 4 years. [medical-dictionary.thefreedictionary.com]

  Over-the-counter nasal sprays containing oxymetazolone (Afrin) or phenylephrine (Allerest) can provide almost immediate relief from nasal congestion. [innvista.com]

  The incubation period generally ranges from 1 to 2 days (4), followed by rhinitis (runny nose), nasal congestion, sore throat, cough, and less frequently headaches for symptomatic individuals. [microchemlab.com]

  Clinical signs: Coughing Fever Sore throat Nasal congestion Disease transmission: HRVs are transmitted from person to person by either direct contact, aerosols from sneezing and coughing or through objects (fomites). [pirbright.ac.uk]

  Symptoms of rhinovirus infection usually develop within 12-72 hours of exposure and include sore throat, nasal congestion, runny nose, cough, hoarseness, headache, ear pressure, sneezing, and nasal irritation. [medicinenet.com]

• Rhinitis

  A prospective case—control study compared 58 adults with perennial allergic rhinitis with 61 adults without allergy for 1 year. Among patients with perennial allergic rhinitis, 43% developed URI compared with 25% of control patients. [pharmacytimes.com]

  Previous and next rhinitis rhino rhinoceros rhinovirus rhizome Rhodes Scholarship rhodium Goldilocks used to describe a situation in which a particular set of qualities or conditions are or have to be exactly right BuzzWord Article More BuzzWords 24/7 [macmillandictionary.com]

  The incubation period generally ranges from 1 to 2 days (4), followed by rhinitis (runny nose), nasal congestion, sore throat, cough, and less frequently headaches for symptomatic individuals. [microchemlab.com]

  Other names simply refer to that part of the body affected such as the eyes (conjunctivitis), nose (rhinitis), sinuses (sinusitis), throat (pharyngitis), voice box or larynx (laryngitis) and the air tubes in the lungs (bronchitis). [lungfoundation.com.au]

• Loss of Appetite

  These symptoms may be accompanied by headache, muscle ache, muscle weakness, malaise and loss of appetite. [news-medical.net]

  The main signs and symptoms include: Sore throat Runny nose (nasal discharge) Nasal congestion Sneezing This may be accompanied by a mild fever, headache, muscle ache or weakness, cough, fatigue and loss of appetite. [solutionsdesignedforhealthcare.com]

  Symptoms include sore throat, runny nose, nasal congestion, sneezing and cough; sometimes accompanied by muscle aches, fatigue, malaise, headache, muscle weakness, or loss of appetite. Fever and extreme exhaustion are more usual in influenza. [en.wikipedia.org]

• Hypotension

  On hospital Day 3, the patient’s situation deteriorated, and she developed hypotension and hypovolemia. Blood analysis revealed decreased WBC counts and elevated C-reactive protein levels (CRP). Her PCT level was 157.97 ng/L. [virologyj.biomedcentral.com]

• Fussiness

  Fussiness, poor eating, sleepiness or low energy in a baby. Signs of an ear infection – complaining about ear pain, tugging or rubbing the ear, etc. Any other severe symptoms or symptoms that last longer than 7 days. [intermountainhealthcare.org]

• Headache

  Infection is characterized by dry scratchy throat, nasal congestion, malaise, and headache. Fever is minimal. Nasal discharge lasts 2 or 3 days. Children may also develop a cough. Type-specific antibodies may last for 2 to 4 years. [medical-dictionary.thefreedictionary.com]

  Signs and Symptoms Rhinovirus can bring on all of the familiar symptoms of a cold: runny nose, sneezing, sore throat, headache, cough, and body aches. [intermountainhealthcare.org]

  The incubation period generally ranges from 1 to 2 days (4), followed by rhinitis (runny nose), nasal congestion, sore throat, cough, and less frequently headaches for symptomatic individuals. [microchemlab.com]

  Symptoms of rhinovirus infection usually develop within 12-72 hours of exposure and include sore throat, nasal congestion, runny nose, cough, hoarseness, headache, ear pressure, sneezing, and nasal irritation. [medicinenet.com]

• Agitation

  After 1 h at room temperature with gentle agitation, the cell suspension was transferred to a 100-mm tissue culture dish containing 12.5 ml of cell growth medium. Plates were further incubated at 27°C without agitation. [ncbi.nlm.nih.gov]

Lastly, no special laboratory workup or particular patterns of radiographic changes were observed in HRV-associated pneumonia. [jtd.amegroups.com]

Diagnosis of rhinovirus infection If findings from a thorough history and physical examination are consistent with a viral etiology and no complications are noted, an aggressive workup is rarely necessary. [emedicine.medscape.com]

• Neutrophilia

  Infection with both HRV-1B and HRV-16 resulted in BAL fluid neutrophilia and lymphocytosis; increased Muc5B protein in BAL fluid; increased viral RNA levels in BAL fluid and lung tissue; and the induction of IFNs, chemokines, IL-1β, and virus-specific [doi.org]

• Streptococcus Pneumoniae

  pneumoniae on patient setting. [ncbi.nlm.nih.gov]

  A role for Streptococcus pneumoniae in virus-associated pneumonia, Nat Med, 2004, vol. 10 (pg. 811 - 3 ) Potential conflicts of interest: R.B.T. reports no conflicts of interest with regard to the subject of this editorial. [academic.oup.com]

  Streptococcus pneumoniae (3, 15%), Klebsiella pneumoniae (3, 15%) and Mycoplasma pneumoniae (2, 10%) were the most common bacterium identified in the study. [jtd.amegroups.com]

  (n=1), Streptococcus pseudopneumoniae (n=1) and S. pneumoniae (n=1). [erj.ersjournals.com]

Treatment of rhinovirus infections Treatment options for rhinovirus colds are unsatisfactory. [doi.org]

Adjusted illness rates (illnesses per sample) by treatment arm were calculated using Poisson regression. [ncbi.nlm.nih.gov]

Abstract Objective: To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation. [ncbi.nlm.nih.gov]

[…] receptor on the cell surface RNA is translated into a large polypeptide that is cleaved by viral proteins acid-labile and thus is not an enterovirus vasodilation and increased vascular permeability causes rhinorrhea replicates in nasopharynx epithelium Prognosis [medbullets.com]

Whether the poor prognosis is due to HRV or the copathogen is not clear. [doi.org]

In addition, HRV has emerged as an important cause of pneumonia for its severity and poor prognosis in infants and children (22,23). [jtd.amegroups.com]

Enrolled patients were classified into two groups as follows: the viral group, if only HRV was detected in etiological examinations; and the viral-bacterial group, if etiological examinations revealed mix viral-bacterial infection. [jtd.amegroups.com]

Ferre, R.A., Brown, E.L., Binford, S.L., Brothers, M.A., DeLisle, D.M., Worland, S.T. (1999) Proc.Natl.Acad.Sci.USA 96 : 11000-11007 PubMed : 10500114 Search on PubMed Search on PubMed Central PubMed Abstract: Human rhinoviruses, the most important etiologic [rcsb.org]

The etiologic agents most often associated with this disease are the respiratory syncytial virus (RSV), parainfluenza, influenza and adenovirus. [scielo.br]

The respiratory virus etiology was analyzed using polymerase chain reaction. RV-positive samples were sequenced. [ncbi.nlm.nih.gov]

[…] rhinovirus [ ri´no-vi″rus ] any member of a genus of picornaviruses, considered to be etiologically associated with the common cold and certain other upper respiratory ailments. [medical-dictionary.thefreedictionary.com]

KEYWORDS: Epidemiology; Genotype; Respiratory tract infection; Rhinovirus; Seasonality [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

Yokoe, Strategies to Prevent Healthcare-Associated Infections through Hand Hygiene, Infection Control & Hospital Epidemiology, 10.1086/677145, 35, 8, (937-960), (2016). [doi.org]

Phillip Allen for assistance with the epidemiologic and statistical portions of this investigation and to Mesdames Dianne Shott. Nancy Hutcheson and Karen Huey and Misses Frances Mnlford. Bettv Carlton, and Jean Lynn for technical assistance. [nejm.org]

Author information 1 Research Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Electronic address: nataliyaapet[email protected]. 2 Research Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. [ncbi.nlm.nih.gov]

A model to investigate the pathophysiology of HRV infection and to test compounds that could treat or protect one from infection or developing symptoms would therefore be very valuable. [clinicaltrials.gov]

Further research should address the relative contribution of viral and host factors and allow a better understanding of the pathophysiological role of rhinovirus infections in infancy. [erj.ersjournals.com]

Authors’ Affiliations (1) Department of Pathophysiology and Allergy Research, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria (2) Department of Medical Biochemistry, Max F. [molcellped.springeropen.com]

Control and Prevention, Beijing 102206, China; Institute for Immunization and Prevention, Beijing CDC, Beijing 100013, China. 5 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206 [ncbi.nlm.nih.gov]

Initial studies demonstrated that the common cold could be prevented by treatment of hands with iodine. [doi.org]

They prevent the pH-mediated uncoating of the viral RNA. [dx.doi.org]