METHODS: To compare the presentation and outcomes of patients with rhinovirus and EV-D68, 103 GenMark rhinovirus positive nasopharyngeal swabs from hospitalized children were retested for EV-D68. [ncbi.nlm.nih.gov]

Virus tests and identification are frequently foregone in the acute presentation of sepsis. [virologyj.biomedcentral.com]

SpaceNext50 Britannica presents SpaceNext50, From the race to the Moon to space stewardship, we explore a wide range of subjects that feed our curiosity about space! [britannica.com]

• Multiple Organ Dysfunction Syndrome

  Multiple organ dysfunction syndrome (MODS) is commonly secondary to severe sepsis or septic shock. [virologyj.biomedcentral.com]

• Common Cold

  For a study published in 2018, a group of scientists in Moscow, Idaho, squirted a common-cold-type virus, either a rhinovirus or a mouse coronavirus, up the noses of white mice. [merriam-webster.com]

  This model shows the structure of rhinovirus, which causes the common cold. Rhinovirus is a widespread virus that is the main cause of the common cold in humans. [biointeractive.org]

  Transmission of rhinovirus colds by self-inoculation. N. Engl. J. Med. 288:1361–1364. ** Turner RB. Epidemiology, pathogenesis, and treatment of the common cold. Ann. Allergy Asthma Immunol. 78(6), 531–539 (1997). [virologyresearchservices.com]

  Clinical studies indicate sinus involvement in common colds. [emedicine.medscape.com]

  Your doctor can determine if you or your child has a cold or the flu and can recommend treatment to help with symptoms. Causes of the Common Cold Many different respiratory viruses can cause the common cold, but rhinoviruses are the most common. [cdc.gov]

• Nasal Congestion

  Clinical signs: Coughing Fever Sore throat Nasal congestion Disease transmission: HRVs are transmitted from person to person by either direct contact, aerosols from sneezing and coughing or through objects (fomites). [pirbright.ac.uk]

  Infection is characterized by dry scratchy throat, nasal congestion, malaise, and headache. Fever is minimal. Nasal discharge lasts 2 or 3 days. Children may also develop a cough. Type-specific antibodies may last for 2 to 4 years. [medical-dictionary.thefreedictionary.com]

  Symptoms of rhinovirus infection usually develop within 12-72 hours of exposure and include sore throat, nasal congestion, runny nose, cough, hoarseness, headache, ear pressure, sneezing, and nasal irritation. [medicinenet.com]

  Over-the-counter nasal sprays containing oxymetazolone (Afrin) or phenylephrine (Allerest) can provide almost immediate relief from nasal congestion. [innvista.com]

• Vascular Disease

  disease, bronchiectasis, interstitial and pulmonary vascular diseases, etc.) [5]. [virologyj.biomedcentral.com]

• Headache

  Signs and Symptoms Rhinovirus can bring on all of the familiar symptoms of a cold: runny nose, sneezing, sore throat, headache, cough, and body aches. [intermountainhealthcare.org]

  Symptoms of the common cold caused by the rhinovirus include sore throat, runny nose, coughing, sneezing, watery eyes, headaches, and body aches. Infants and children may develop fever, and otitis media. [health.hawaii.gov]

  Infection is characterized by dry scratchy throat, nasal congestion, malaise, and headache. Fever is minimal. Nasal discharge lasts 2 or 3 days. Children may also develop a cough. Type-specific antibodies may last for 2 to 4 years. [medical-dictionary.thefreedictionary.com]

  Symptoms usually include: sore throat runny nose coughing sneezing headaches body aches Most people recover within about 7-10 days. [cdc.gov]

  These symptoms may be accompanied by headache, muscle ache, muscle weakness, malaise and loss of appetite. [news-medical.net]

Diagnosis of rhinovirus infection If findings from a thorough history and physical examination are consistent with a viral etiology and no complications are noted, an aggressive workup is rarely necessary. [emedicine.medscape.com]

Lastly, no special laboratory workup or particular patterns of radiographic changes were observed in HRV-associated pneumonia. [jtd.amegroups.com]

Treatment of rhinovirus infections Treatment options for rhinovirus colds are unsatisfactory. [doi.org]

Adjusted illness rates (illnesses per sample) by treatment arm were calculated using Poisson regression. [ncbi.nlm.nih.gov]

As with many other viruses, treatment for rhinovirus usually means managing the symptoms until the infection clears. (There’s no commonly used treatment that acts on this group of viruses.) [intermountainhealthcare.org]

Abstract Objective: To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation. [ncbi.nlm.nih.gov]

[…] receptor on the cell surface RNA is translated into a large polypeptide that is cleaved by viral proteins acid-labile and thus is not an enterovirus vasodilation and increased vascular permeability causes rhinorrhea replicates in nasopharynx epithelium Prognosis [medbullets.com]

Prognosis The prognosis for rhinovirus infection is excellent. The most common manifestation of infection, the common cold, is mild and self-limited. [emedicine.medscape.com]

Whether the poor prognosis is due to HRV or the copathogen is not clear. [academic.oup.com]

The etiologic agents most often associated with this disease are the respiratory syncytial virus (RSV), parainfluenza, influenza and adenovirus. [scielo.br]

The respiratory virus etiology was analyzed using polymerase chain reaction. RV-positive samples were sequenced. [ncbi.nlm.nih.gov]

[…] rhinovirus [ ri´no-vi″rus ] any member of a genus of picornaviruses, considered to be etiologically associated with the common cold and certain other upper respiratory ailments. [medical-dictionary.thefreedictionary.com]

RHINOVIRUSES have been associated with 10 to 30 per cent of acute upper respiratory illnesses in several groups of adults. 1 2 3 4 5 6 In March, 1963, a study was undertaken to define the etiology and epidemiology of acute respiratory disease in a population [nejm.org]

[…] picornavirus causes the “common cold” does not cause viral meningitis or gastroenteritis transmission via direct contact Epidemiology incidence very common demographics all ages risk factors immunosuppression sick contacts smoking recent travel on an airplane Etiology [medbullets.com]

KEYWORDS: Epidemiology; Genotype; Respiratory tract infection; Rhinovirus; Seasonality [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

Yokoe, Strategies to Prevent Healthcare-Associated Infections through Hand Hygiene, Infection Control & Hospital Epidemiology, 10.1086/677145, 35, 8, (937-960), (2016). [doi.org]

Differential diagnosis of HRV and HEV infections is epidemiologically important. [certest.es]

Subsequent studies have defined the epidemiology and clinical implications of these infections. [academic.oup.com]

Author information 1 Research Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. Electronic address: [email protected] 2 Research Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia. [ncbi.nlm.nih.gov]

A model to investigate the pathophysiology of HRV infection and to test compounds that could treat or protect one from infection or developing symptoms would therefore be very valuable. [clinicaltrials.gov]

Further research should address the relative contribution of viral and host factors and allow a better understanding of the pathophysiological role of rhinovirus infections in infancy. [erj.ersjournals.com]

Authors’ Affiliations (1) Department of Pathophysiology and Allergy Research, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria (2) Department of Medical Biochemistry, Max F. [molcellped.springeropen.com]

Control and Prevention, Beijing 102206, China; Institute for Immunization and Prevention, Beijing CDC, Beijing 100013, China. 5 National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206 [ncbi.nlm.nih.gov]

Initial studies demonstrated that the common cold could be prevented by treatment of hands with iodine. [doi.org]

They prevent the pH-mediated uncoating of the viral RNA. [dx.doi.org]