Presentation
ADR Presented by Dr. Richard Markell Cellulitis Presented by Dr. Phoebe Smith Foal Diarrhea Presented by Dr. Bonnie Barr Laminitis Presented by Dr. Luis Castro Bone Injury vs Bone Infection Presented by Dr. [stablelab.com]
It sometimes affects humans presenting as cavitary pneumonia. Immunocompromised patients, including HIV-infected patients, are more susceptible to R. equi infection. [liebertpub.com]
Recently, human infestation has been seen in immunocompromised patients, presenting primarily with pulmonary manifestations. [jamanetwork.com]
We present the case of a patient with chronic myeloid leukaemia who had received allogenic stem cell transplant and presented to the hospital with clinical picture of pneumonia. [casereports.bmj.com]
Entire Body System
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Weight Loss
Luis Castro Weight Loss Work Up Presented by Dr. Phoebe Smith Peritonitis Presented by Dr. Korin Potenza Screening for Rhodococcus Equi Presented by Dr. Jaye McCracken Septic Joints Presented by Dr. [stablelab.com]
Clinical signs of Rhodococcus equi can include fever, depression, coughing, weight loss, swollen joints, colic and/or diarrhea. [cahosp.com]
The respiratory process is insidious, manifesting as high fever, cough, dyspnea, chest pain and weight loss. 2 It is identified and diagnosed from the culture of affected tissue samples. 4 Blood cultures are positive in 50% of immunocompromised subjects [archbronconeumol.org]
Foals with abdominal involvement often present with fever, depression, anorexia, weight loss, colic, and diarrhea. [msdvetmanual.com]
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Fever of Unknown Origin
Richard Markell Fever of Unknown Origin Presented by Dr. Phoebe Smith Pending Colitis Presented by Dr. Luis Castro Weight Loss Work Up Presented by Dr. Phoebe Smith Peritonitis Presented by Dr. [stablelab.com]
[…] of unknown origin. [archbronconeumol.org]
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Weakness
Rodney Belgrave Weak Neonatal Foal Presented by Dr. Bonnie Barr Anaplasma Presented by Dr. Rodney Belgrave Monitoring the Quarantined Patient Presented by Dr. Rodney Belgrave Coughing Horse Presented by Dr. [stablelab.com]
[…] ultrasonographic evidence of pulmonary abscesses in addition 8 cm, a positive microbiology out of tracheobronchial secretion and positive response to antibiotic treatment (azithromycin 10 mg/kg BDW 24q PO and rifampicin 10 mg/kg BDW 12q PO) within a weak [refubium.fu-berlin.de]
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Asymptomatic
After 16 months of follow-up, the patient was asymptomatic and had neither recurrence nor immunological disturbances. [erj.ersjournals.com]
Three months later, the pulmonary mass had disappeared and 12 months later the patient remained asymptomatic with periodic check-ups at the haematology clinic. Discussion The first infection caused by R. equi in man was described in 1967. [archbronconeumol.org]
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Chronic Infection
Received: 8 November 2019 / Revised: 1 December 2019 / Accepted: 3 December 2019 / Published: 4 December 2019 Microbial biofilm has been implicated in a wide range of chronic infections. [mdpi.com]
Gastrointestinal
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Colic
Jan-Hein Swagemakers Colic Presented by Dr. Korin Potenza Managing Nations Cup Horse Presented by Dr. Jan-Hein Swagemakers Need help? If you haven't found what you need, contact us: Request a Callback [stablelab.com]
Clinical signs of Rhodococcus equi can include fever, depression, coughing, weight loss, swollen joints, colic and/or diarrhea. [cahosp.com]
Foals with abdominal involvement often present with fever, depression, anorexia, weight loss, colic, and diarrhea. [msdvetmanual.com]
Neurologic
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Confusion
Can also be confused with Micrococcus, Bacillus or Mycobacteria species. There's more to see -- the rest of this entry is available only to subscribers. Last updated: November 8, 2019 Citation Fabre, Valeria. "Rhodococcus Equi." [hopkinsguides.com]
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Asthenia
He attended the emergency department due to a decreased level of consciousness, asthenia and drowsiness. Physical examination showed blood pressure 73/47 mmHg, heart rate 120 beats/min, mild fever and basal oxygen saturation of 86%. [archbronconeumol.org]
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Apathy
Physical examination upon admission revealed disorientation in time and space, frank bradypsychia, mild right brachial paresis, motor aphasia, apathy, and aboulia. [elsevier.es]
Workup
X-Ray
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Air Bronchogram
Chest X-ray showed a rounded high attenuation area in the right hemithorax, with no air bronchogram, measuring 5 cm 4 cm, on the right parahilar region ( Fig. 1 a). [archbronconeumol.org]
Microbiology
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Staphylococcus Aureus
The radiological differential diagnosis should be made mainly with pneumonia due to Pneumocystis jirovecci or Staphylococcus aureus, central bronchogenic carcinoma and pulmonary tuberculosis. [archbronconeumol.org]
Colonoscopy
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Colitis
Phoebe Smith Pending Colitis Presented by Dr. Luis Castro Weight Loss Work Up Presented by Dr. Phoebe Smith Peritonitis Presented by Dr. Korin Potenza Screening for Rhodococcus Equi Presented by Dr. Jaye McCracken Septic Joints Presented by Dr. [stablelab.com]
Although pneumonia is the most common clinical manifestation, up to 74% of foals may concurrently have extrapulmonary disorders, including both extrapulmonary infections (abdominal abscessation, colitis, osteomyelitis) and immune-mediated disorders (nonseptic [dovepress.com]
He had a history of ulcerative colitis diagnosed 15 years prior, which was well controlled on mesalazine. A surveillance colonoscopy 18 months prior to the presentation was normal. [nzma.org.nz]
Treatment
Antibiotic treatment was the mainstay of treatment while some patients had surgical treatment in combination or as the sole therapy. Antibiotic treatment was described in 24 (92%) patients. [nzma.org.nz]
Intravenous treatment was maintained for 2 months, followed by 4 more months of oral azithromycin and trimethoprim-sulfametoxazole. After 2 weeks of treatment, respiratory clinical signs had resolved and chest X-ray was normal. [archbronconeumol.org]
Recent evidence suggests that a high proportion of foals identified via screening methods such as ultrasonographic evaluation of the thorax can recover without treatment, questioning the “trigger” required for treatment of identified cases. [dovepress.com]
Prompt diagnosis, early initiation of antiretroviral treatment and combined antimicrobial treatment seem to be effective to eradicate the infection and to improve the outcome. [liebertpub.com]
Prognosis
The prognosis for survival for foals with R. equi pneumonia is good, especially in foals mildly or subclinically affected, as is the prognosis for future athletic performance. [dovepress.com]
The prognosis for foals with abdominal forms of R equi is less favorable than for those with pulmonary disease. Septic physitis and osteomyelitis are less common extrapulmonary sites of infection. [msdvetmanual.com]
With respect to the prognosis, the mortality reaches 50% in HIV patients, 25% in other types of immunosuppression and 11% in immunocompromised patients. 5 It is exceptionally observed in immunocompromised patients who do not have HIV, as in our case, [archbronconeumol.org]
We have focused mainly on pulmonary infection as it is the commonest manifestation and has the worst prognosis. [nzma.org.nz]
Epidemiology
Compelling epidemiologic data indicate pulmonary infection probably originates within the first week of life. (See also Rhodococcosis .) R equi is a gram-positive, facultative intracellular pathogen that is nearly ubiquitous in soil. [msdvetmanual.com]
Prevention
Management of R. equi infections, in particular on farms with endemic disease, combines appropriate treatment of affected foals with preventative measures targeted at preventing infection and identifying foals before the development of severe disease. [dovepress.com]
Administration of hyperimmune plasma might reduce the incidence and severity of R equi within the herd, but it is not completely effective in preventing disease. [msdvetmanual.com]