The spotted fever rickettsia, Rickettsia helvetica, is mostly reported to present a flu-like self-limiting disease. [ncbi.nlm.nih.gov]

• Fever

  PATHOGENESIS: Typhus, spotted fever and trench fever are transmitted via arthropod vectors; Q fever is acquired via inhalation or ingestion of contaminated milk or food. [myplace.frontier.com]

  A 17-year-old otherwise healthy girl was admitted to Department of Zoonotic and Tropical Diseases because of fever, eschar and rash. [ncbi.nlm.nih.gov]

  On day 7 after the second onset of fever, the patient was able to work but still felt ill and had a slight fever (37.6°C). [doi.org]

• Inflammation

  Once inside your bloodstream, the Rickettsia invade the cells that line your blood vessels, causing inflammation and leading to an immune response. It is this inflammation and host immune reaction that leads to the symptoms of the disease. [study.com]

  Histopathology Histological changes have been classified into the broad category of necrosis and inflammation. [thefishsite.com]

  Complications of typhus include: Inflammation of the lungs or liver Meningoencephalitis Acute renal failure Multiple organ failure. [dermnetnz.org]

• Lymphadenopathy

  […] necrosis erythema and lymphadenopathy (DEBONEL). [ncbi.nlm.nih.gov]

  The most frequent acute symptoms observed were fever (100%), headache (71%), arthralgia (43%), myalgia (43%), cough (43%), rash (maculopapular/petechial) (43%), nausea (29%), pharyngitis (29%), and lymphadenopathy (29%). [doi.org]

• Fishing

  P. salmonis replicates within membrane-bound cytoplasmic vacuoles in selected fish cell lines and in the cells of tissues throughout infected fish. P. salmonis is the first of the RLO of fish to be fully characterized. [thefishsite.com]

  Fish Health Section, Asian Fisheries Society, Manila, Philippines. pp. 165-172. Romero, X., J.F. Turnbull and R. Jiménez. 2000. [dfo-mpo.gc.ca]

  8 (2009) DOI: 10.4269/ajtmh.2009.81.187 文献 PMID: 19635868 著者 Newton PN, Rolain JM, Rasachak B, Mayxay M, Vathanatham K, Seng P, Phetsouvanh R, Thammavong T, Zahidi J, Suputtamongkol Y, Syhavong B, Raoult D タイトル Sennetsu neorickettsiosis: a probable fish-borne [genome.jp]

  Patient 6’s illness may have been rickettsial in nature because of the appropriate incubation time after a fishing trip in an area endemic for ticks. [doi.org]

• Chills

  Other symptoms included myalgia (n = 3), chills (n = 3), fatigue (n = 2), arthralgia (n = 2), and headache (n = 2). [ncbi.nlm.nih.gov]

  Case Report 24 year old male was admitted in downtown hospital with history of high grade fever associated with chill, headache, yellowish discoloration of urine, rash in abdomen and chest of 3weeks duration. [pubs.sciepub.com]

  This is often accompanied by muscle aches and chills. The fever can be so high that the patient hallucinates or loses consciousness. 'Typhus' in Greek literally means 'stuporous' after this classic symptom. [study.com]

  Patient 1: A 58-year-old male who owned cats was admitted to the hospital because of fever, chills, oppressive headache and diffuse abdominal pain in the last four days. Physical exam only revealed moderate tenderness to abdominal palpation. [elsevier.es]

• Nausea

  Tabs Content Clinical Overview Diagnosis Indications for Testing Tick bite exposure and relevant epidemiologic setting Fever, headache, myalgia, nausea, vomiting; rash 2-5 days after fever Laboratory Testing Diagnosis and laboratory confirmation recommendations [arupconsult.com]

  Symptoms (incubation time: 5-7 days): Fever, nausea, vomiting, severe headache, lymphadenitis, exanthema. [arminlabs.com]

  Experience of the self-reported symptoms nausea (p = 0.006) and radiating pain (p = 0.041) was more common among those with recent, current or probable infection compared to those who did not seroconvert. [ncbi.nlm.nih.gov]

  She returned four days later with persistent fever, anorexia, irritability, photophobia, cough, diffuse myalgias, nausea, vomiting, and a rash. [web.uconn.edu]

  Patients infected with R. rickettsii generally have nonspecific symptoms including fever, nausea, vomiting, muscle pain, lack of appetite, and severe headache after an incubation period about 5-10 days following an infected tick bite. [microbewiki.kenyon.edu]

• Myalgia

  Most patients infected with R. sibirica showed typical clinical symptoms, including high-grade fever (38.9-39.5°С), myalgia, rash, eschar at the site of the tick bite, and elevated levels of serum aminotransferases. [ncbi.nlm.nih.gov]

  Five days after removing the tick (day 5), an influenzalike illness with myalgia and arthralgia developed. [doi.org]

  Tabs Content Clinical Overview Diagnosis Indications for Testing Tick bite exposure and relevant epidemiologic setting Fever, headache, myalgia, nausea, vomiting; rash 2-5 days after fever Laboratory Testing Diagnosis and laboratory confirmation recommendations [arupconsult.com]

  Complications (app. 13%): peri-/myocarditis, kidney insufficiency, pneumonia, encephalitis, gastrointestinal bleedings, anemia, hepatitis, myalgia [arminlabs.com]

• Skin Rash

  Most rickettisal species produce a constellation of high fever, headaches, and skin rash. Most Rickettsial species are transmitted by arthropod vectors during blood meals. Treatment for all Rickettsial diseases is doxycycline or chloramphenicol. [pathwaymedicine.org]

  This is followed by dissemination via the vascular system producing vasculitis and a skin rash. These lesions may become necrotic. [myplace.frontier.com]

  Rash (small, tiny bumps on the skin) normally starts on the limbs and may eventually involve the whole body. [tickbites.net]

  Some other conditions that may be confused with tick bite fever are infection with Neisseria meningitidis (the meningococcus, which causes meningitis and a skin rash), measles and German measles. [health24.com]

• Eruptions

  Several days after an eschar appears, the following can develop: Fever Headache Rash (sparse maculopapular or papulovesicular eruptions on the trunk and extremities) Muscle aches NOTE: R. parkeri rickettsiosis can be difficult to distinguish from RMSF [cdc.gov]

  The infection tends to be moderate to severe and a generalised maculopapular eruption is seen. The systemic features of epidemic louse-borne typhus include neurological symptoms (eg, deafness and delirium) and abdominal pain. [dermnetnz.org]

  The rash is a diffuse macular (featuring elevated discoloration) rash, is most prominent on wrists and ankles, which will usually erupt three or four days after the onset of fever. [web.uconn.edu]

  Cutaneous eruptions in Indian tick typhus. Int J Dermatol. In article [7] Current medical diagnosis and treatment-2015. Chapter 32-rickettsial disease. [pubs.sciepub.com]

  She had a temperature of 39°C and a widespread macular, blanching eruption over her trunk and limbs, including the palms and soles. [mja.com.au]

• Headache

  Clinical features are generally mild, characterized by eschar, fever, headache, malaise and lymphadenopathy. Antigenic similarity among rickettsiae leads to cross-reactive antibody responses; definitive diagnosis requires molecular methods. [ncbi.nlm.nih.gov]

  She was febrile (38.5°C) and reported headache, nausea, and abdominal pain. She had no eschar or rash. [doi.org]

  Usually a fever accompanies the appearance of the eschar along with other discomforts such as headache. Lymph nodes near the site usually swell. [tickbites.net]

• Rickettsia Typhi

  Vectors for rickettsia typhi Classification of rickettsia typhi Epidemic louse-borne typhus Epidemic louse-borne typhus is distributed worldwide but is associated with emergency situations. [dermnetnz.org]

  KEYWORDS: California; Ctenocephalides felis; Rickettsia felis; Rickettsia typhi; cat flea [ncbi.nlm.nih.gov]

  References for Rickettsia typhi Complete Genome Sequence of Rickettsia typhi and Comparison with Sequences of Other Rickettsiae. McLeod, M.P. et al. J. Bacteriol. 2004 186: 5842-5855. [hgsc.bcm.edu]

• Rickettsia Prowazekii

  prowazekii/genetics* Rickettsia prowazekii/pathogenicity Transcription, Genetic Virulence/genetics Substances DNA, Bacterial DNA, Mitochondrial Membrane Proteins Secondary source ID GENBANK/AJ235270 GENBANK/AJ235271 GENBANK/AJ235272 GENBANK/AJ235273 [ncbi.nlm.nih.gov]

  Affiliations PMID: 9823893 DOI: 10.1038/24094 The genome sequence of Rickettsia prowazekii and the origin of mitochondria S G Andersson et al. Nature. 1998. [pubmed.ncbi.nlm.nih.gov]

  Genome information T number T00018 Org code rpr Aliases RICPR, 272947 Full name Rickettsia prowazekii Madrid E Definition Rickettsia prowazekii Madrid E Annotation manual Taxonomy TAX: 272947 Lineage Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales [genome.jp]

  Other Rickettsia include Rickettsia prowazekii, which causes typhus, R. rickettsii, which causes Rocky Mountain spotted fever, and Rickettsia akari, which causes rickettsialpox. [microbewiki.kenyon.edu]

• Rickettsia Rickettsii

  R. rickettsii is the only Rickettsia species that utilizes ABM. [web.uconn.edu]

  Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa. Infect Immun 76(2):542-50. Fournier PE, et al., 2009. [mgc.ac.cn]

  Key Words: Rickettsia rickettsii, Brazilian spotted fever, sepsis, ARDS. Rickettsia rickettsii infections can cause a wide range of clinical manifestations, ranging from asymptomatic or mild febrile illness to overwhelming and fatal disease [1-6]. [scielo.br]

  Serological antibody-absorption tests with purified antigens of R. parkeri and Rickettsia rickettsii, associated with immunofluorescence assay indicated that the patients in two cases were infected by R. parkeri. [ncbi.nlm.nih.gov]

  What are Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species? The Rickettsiae are a genus of Gram-negative coccobacilli, which includes two major groups of bacteria. [youtube.com]

• Rickettsia Conorii

  […] infection.tif 2.216 × 1.784; 825 KB Rickettsia conorii in cytoplasm.gif 600 × 480; 265 KB Rickettsia conorii in Vero.gif 600 × 450; 138 KB Rickettsia rickettsii.jpg 297 × 278; 17 KB Rickettsia rpsL leader.pdf 1.275 × 1.650; 8 KB Rickettsia rpsL leader.png [commons.wikimedia.org]

  Nine ticks tested positive for Ri. conorii subsp. caspia (marking the first documentation of this subspecies in France), 7 tested positive for Ri. massiliae, and 4 tested positive for both rickettsiae. [ncbi.nlm.nih.gov]

  Pruebas disponibles para Rickettsia PCR Rickettsia-DNA-PCR en sangre (2x tubo EDTA) Bacteria Vectores Síntomas Complicaciones Bacteria: Rickettsia conorii, R. rickettsii, R. helvetica, R. slovaca, R. prowazekii (no reacciona a la tinción de gram, intracelular [arminlabs.com]

  Philip, 1950 Species Rickettsia bellii Philip et al., 1983 Species Rickettsia canadensis McKiel et al., 1967 Species Rickettsia conorii Brumpt, 1932 Species Rickettsia felis Bouyer et al., 2001 emend. [itis.gov]

• Coxiella Burnetii

  KEYWORDS: Bartonella spp.; Coxiella burnetii; Rickettsia spp.; South Africa; Ticks; Vector-borne [ncbi.nlm.nih.gov]

Increased recognition of QTT will enable consideration of and prompt treatment of R. australis infection by clinicians in Australia. [ncbi.nlm.nih.gov]

Treatment: Antimicrobial treatment as recommended by the doctor. Immunisation: None available. Case follow up: Is conducted by Public Health Units and the Communicable Disease Control Directorate. [ww2.health.wa.gov.au]

Treatment Treatment is usually with the tetracycline antibiotic doxycycline which reduces the duration and severity of infection. Prevention Exclusion of people with rickettsial infections from childcare, preschool, school and work is not necessary. [sahealth.sa.gov.au]

Treatment of RMSF Rocky Mountain spotted fever in pregnancy The most effective treatment is tetracycline. [babymed.com]

Identification of specific etiology is important for appropriate treatment in order to optimize prognosis. [neurology.org]

No influence of GB virus C replication on the prognosis in a cohort of HIV‐1‐infected patients, AIDS, 2002, vol. 16 (pg. 2482 - 5 ) 16. [doi.org]

Rickettsia was suggested as one etiology of Buerger's disease long ago. We report a patient with Buerger's disease for whom a left below-knee amputation was done. [ncbi.nlm.nih.gov]

Identification of specific etiology is important for appropriate treatment in order to optimize prognosis. [neurology.org]

Rickettsia IFA IgM For the detection and semi-quantitation of IgM antibodies to R. rickettsii, the etiologic agent of Rocky Mountain spotted fever, and to R. typhi, the etiologic agent of murine typhus, in human serum. [focusdx.com]

Epidemiological and clinical evidences, coupled with our serological analysis, suggest that R. parkeri is the etiological agent of human cases of spotted fever in Uruguay, a disease that has been recognized in that country as cutaneous-ganglionar rickettsiosis [ncbi.nlm.nih.gov]

His particular research focus encompasses the characterisation of an animal model for transmission and immuno-pathophysiology studies in scrub typhus, building towards vaccine development. [ndm.ox.ac.uk]

MORU also has ongoing studies to determine the pathophysiological mechanisms of scrub typhus infection. [tropmedres.ac]

Host- and microbe-related risk factors for and pathophysiology of fatal Rickettsia conorii infection in Portuguese patients. J Infect Dis 198 : 576 – 585. 49. Horney LF ,, Walker DH. 1988. [asmscience.org]

Prevention Exclusion of people with rickettsial infections from childcare, preschool, school and work is not necessary. There is no vaccine available to prevent infection. [sahealth.sa.gov.au]

Prevention of rickettsia typhi There are no existing vaccines for rickettsial infections. Rickettsial infections can be prevented by taking measures to reduce exposure to lice and fleas. [dermnetnz.org]

That, together with it being treatable and as such preventable, makes a huge case. [ndm.ox.ac.uk]