Presentation
The limited number and weak reactivity of linear peptide epitopes observed with human and rabbit sera, possibly due to a lack of the methylated amino acids which are present in rickettsia-derived SPA, suggest that the present approach will not provide [ncbi.nlm.nih.gov]
Hence, it must be presumed that people infected with the human body louse are present in Italy. [unboundmedicine.com]
Entire Body System
- Gangrene
Causes blood clots that lead to gangrene of extremities, nose, ears, & genitalia. Human body louse on flying squirrel (in N. [quizlet.com]
In severe cases, extensive thrombosis in the fingers can lead to gangrenous necrosis of the digits. Confusion and somnolence are seen in a large number of patients. [pathwaymedicine.org]
Gangrene of the distal extremities can occur in severe cases. Mortality occurs most often in the second week of illness and ranges as high as 20% without antibiotics; mortality rates are higher in older adults. [centerforhealthsecurity.org]
Respiratoric
- Pneumonia
Rhinoscleroma, Klebsiella pneumonia Klebsiella granulomatis Granuloma inguinale Klebsiella oxytoca Escherichia coli : Enterotoxigenic Enteroinvasive Enterohemorrhagic O157:H7 O104:H4 Hemolytic-uremic syndrome Enterobacter aerogenes / Enterobacter cloacae [en.wikipedia.org]
Cough is frequent, and pneumonia may also be present. Mental status changes and clouding, from which the disease gets its name-typhus is the Greek word for cloud-portend a poor prognosis. [centerforhealthsecurity.org]
Skin
Neurologic
- Agitation
Cells were subjected to 3 cycles at the maximum agitation setting for 10 seconds with at least 10 seconds of cooling on ice between each agitation. [journals.plos.org]
[…] antibody and 10 μl protein A Sepharose beads for 18 h at 4°C with agitation. [jb.asm.org]
Workup
Microbiology
- Rickettsia Rickettsii
Rickettsia rickettsii is considered the prototypical infectious organism in the group. [en.wikipedia.org]
What are Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species? The Rickettsiae are a genus of Gram-negative coccobacilli, which includes two major groups of bacteria. [youtube.com]
Rickettsia prowazekii - a species causing epidemic typhus. Rickettsia rickettsii - the agent of Rocky Mountain spotted fever. Rickettsia sibirica - the agent of Siberian or North Asian tick typhus. [medical-dictionary.thefreedictionary.com]
Rickettsia strains available for MIF: Micro-dot arrays within each slide well include up to 6 of the following species: Rickettsia rickettsii Rickettsia canadensis Rickettsia parkeri Rickettsia akari Rickettsia montanensis Rickettsia felis (worldwide) [genoprice.com]
Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa. Infect Immun 76(2):542-50. Fournier PE, et al., 2009. [mgc.ac.cn]
- Chlamydia
[…] that Puerperal Fever ( Child Bed Fever) was contagious and transmitted from doctor or midwife to a patient giving birth Insect vector known for causing the disease Malaria is: Culex quinquefascratus causes SLE ( St Louis Encephalitis) Rickettsia nad Chlamydiae [quizlet.com]
However unlike Chlamydia, Mycoplasma, and Ureaplasma, Rickettsial organisms possess true cell walls similar to other gram-negative bacteria.[9] The majority of Rickettsia bacteria are susceptible to antibiotics of the tetracycline group. [youtube.com]
[…] anoxygenic photosynthetic bacteria are more closely related to E. coli than to some other lineages of anoxygenic photosynthetic bacteria; Mycoplasma and other cell-wall deficient species are members of the Gram-positive clade; the medically important Chlamydia [books.google.it]
Examples include gonorrhea, genital herpes, human papillomavirus infection, HIV/AIDS, chlamydia, and syphilis. Shigellosis is an infectious, diarrheal disease caused by a group of bacteria called Shigella. [niaid.nih.gov]
There is a complete lack of mut genes in M. genitalium, but mutL and mutHLY have been identified in B. burgdorferi and Chlamydia trachomatis. [doi.org]
- Rickettsia Orientalis
Synonyms: " Theileria tsutsugamushi " Hayashi 1920, " Rickettsia orientalis " Nagayo et al. 1930, " Rickettsia akamushi " Kawamura and Imagawa 1931. [bacterio.net]
Treatment
Treatment with tetracycline antibiotics is usually successful.[citation needed] References[edit] ^ a b Kurland, Charles G.; Andersson, Siv G. E.; Zomorodipour, Alireza; Andersson, Jan O.; Sicheritz-Pontén, Thomas; Alsmark, U. [en.wikipedia.org]
Abstract The effect of lymphokine treatment of mouse and human fibroblast cell lines on the growth of Rickettsia prowazekii within the fibroblasts was studied. [ncbi.nlm.nih.gov]
Treatment Doxycycline or chloramphenicol [pathwaymedicine.org]
Prognosis
Mental status changes and clouding, from which the disease gets its name-typhus is the Greek word for cloud-portend a poor prognosis. These symptoms may include restlessness, delirium, twitching, and hallucinations. [centerforhealthsecurity.org]
Gray You can also search for this author in Further reading Esophageal squamous cell carcinoma with low mitochondrial copy number has mesenchymal and stem-like characteristics, and contributes to poor prognosis Yasunori Masuike, Koji Tanaka, Tomoki Makino [nature.com]
Etiology
Abstract Rickettsia prowazekii, the etiologic agent for epidemic typhus, and Borrelia recurrentis, the etiologic agent of relapsing fever, both utilize the same vector, the human body louse (Pediculus humanus), to transmit human disease. [ncbi.nlm.nih.gov]
Engelsk definition A species of gram-negative, aerobic bacteria that is the etiologic agent of epidemic typhus fever acquired through contact with lice ( TYPHUS, EPIDEMIC LOUSE-BORNE ) as well as Brill's disease. [mesh.kib.ki.se]
Abstract Rickettsia prowazekii, the etiologic agent of epidemic typhus, is a potential biological threat agent. Lysine methylation of OmpB (outer membrane protein) of Rickettsia correlates with the bacterial virulence. [fasebj.org]
Species group: Typhus group Species: R. prowazekii Binomial name Rickettsia prowazekii da Rocha-Lima, 1916 Rickettsia prowazekii is a species of gram-negative, alphaproteobacteria, obligate intracellular parasitic, aerobic bacillus bacteria that is the etiologic [en.wikipedia.org]
Epidemiology
This review of the epidemiology of head louse and body louse infestations, and of LBET, indicates that head lice are potential vectors of R. prowazekii in the field. [ncbi.nlm.nih.gov]
[…] www.pubmed.gov Multispacer typing of Rickettsia prowazekii enabling epidemiological studies of epidemic typhus. Zhu Y, Fournier PE, Ogata H, Raoult D. [headlice.org]
The importance for human epidemiology is expected to be limited. Late relapse of epidemic typhus (Brill–Zinsser disease) might be the source of a re-emerging outbreak. [ecdc.europa.eu]
Natural Modes of Infection The epidemiology of rickettsial infections reflects the prevalence of rickettsiae in the vector population and the interactions of arthropod vectors with humans. [ehs.unc.edu]
Pathophysiology
Summarize the pathophysiology of epidemic typhus. Describe the use of serological tests in the evaluation of epidemic typhus. [ncbi.nlm.nih.gov]
Prevention
Abstract Rickettsia prowazekii, the etiologic agent of louse-borne typhus, is listed as a category B agent under the select agent list of the United States Centers for Disease Control and Prevention. [ncbi.nlm.nih.gov]
Prevention Exclusion of people with rickettsial infections from childcare, preschool, school and work is not necessary. There is no vaccine available to prevent infection. [sahealth.sa.gov.au]
The infection is also thought to have thwarted Napoleon's invasion of Russia by creating a burden of disease among the troops so high as to prevent them from mounting a successful campaign. [centerforhealthsecurity.org]