The limited number and weak reactivity of linear peptide epitopes observed with human and rabbit sera, possibly due to a lack of the methylated amino acids which are present in rickettsia-derived SPA, suggest that the present approach will not provide[ncbi.nlm.nih.gov]
In addition they did not react with Neorickettsia risticii, N. sennetsu, Franciscella persica, Bartonella quintana, Legionellapneumophila, Proteus mirabilis, Salmonella enterica, Escherichia coli, and Staphylococcus aureus.[ncbi.nlm.nih.gov]
Pyruvate dehydrogenase (E1) consists of two subunits (α and β) in R. prowazekii, mitochondria and Gram-positivebacteria; the corresponding genes are clustered in the genome.[doi.org]
Pyruvate dehydrogenase (E1) consists of two subunits (α and β) in R. prowazekii , mitochondria and Gram-positivebacteria; the corresponding genes are clustered in the genome.[nature.com]
Abstract The effect of lymphokine treatment of mouse and human fibroblast cell lines on the growth of Rickettsia prowazekii within the fibroblasts was studied.[ncbi.nlm.nih.gov]
Rocky Mountain spotted fever in pregnancy: differential diagnosis and treatment. Southern Med J 1982;75:1063-1066. [PubMed] 1 2 . Huys J, Freyens P, Kayihigi J, Van den Berghe G. Treatment of epidemic typhus.[antimicrobe.org]
Prophylactic treatment with doxycycline can be used in exposed individuals. A vaccine is not currently available, though many have been tested in the past without much reduction in incidence of disease.[centerforhealthsecurity.org]
Mental status changes and clouding, from which the disease gets its name-typhus is the Greek word for cloud-portend a poor prognosis. These symptoms may include restlessness, delirium, twitching, and hallucinations.[centerforhealthsecurity.org]
Delay in appropriate antibiotic therapy is the main factor for poor prognosis in patients involved with rickettsial diseases, especially for epidemic typhus which is fatal in about 15% of cases when untreated ( 34 ).[antimicrobe.org]
Abstract Rickettsia prowazekii, the etiologic agent for epidemic typhus, and Borrelia recurrentis, the etiologic agent of relapsing fever, both utilize the same vector, the human body louse (Pediculus humanus), to transmit human disease.[ncbi.nlm.nih.gov]
Engelsk definition A species of gram-negative, aerobic bacteria that is the etiologic agent of epidemic typhus fever acquired through contact with lice ( TYPHUS, EPIDEMIC LOUSE-BORNE ) as well as Brill's disease.[mesh.kib.ki.se]
Abstract Rickettsia prowazekii, the etiologic agent of epidemic typhus, is a potential biological threat agent. Lysine methylation of OmpB (outer membrane protein) of Rickettsia correlates with the bacterial virulence.[fasebj.org]
Rickettsia prowazekii appearance small Gram-negative short rods or coccobacilli nonmotile obligate intracellular parasite Infections caused by Rickettsia prowazekii Rickettsia prowazekii is the etiologic agent of epidemic typhus , transmitted in the feces[bacteria.cz]
This review of the epidemiology of head louse and body louse infestations, and of LBET, indicates that head lice are potential vectors of R. prowazekii in the field.[ncbi.nlm.nih.gov]
[…] www.pubmed.gov Multispacer typing of Rickettsia prowazekii enabling epidemiological studies of epidemic typhus. Zhu Y , Fournier PE , Ogata H , Raoult D .[headlice.org]
Natural Modes of Infection The epidemiology of rickettsial infections reflects the prevalence of rickettsiae in the vector population and the interactions of arthropod vectors with humans.[ehs.unc.edu]
In fact, BZD presents with milder symptoms and is rarely fatal. [7] [8] Pathophysiology The human body louse is only a vector and not a reservoir because infected lice die five to seven days after they become infected with R. prowazekii .[ncbi.nlm.nih.gov]
Abstract Rickettsia prowazekii, the etiologic agent of louse-borne typhus, is listed as a category B agent under the select agent list of the United States Centers for Disease Control and Prevention.[ncbi.nlm.nih.gov]
The infection is also thought to have thwarted Napoleon's invasion of Russia by creating a burden of disease among the troops so high as to prevent them from mounting a successful campaign.[centerforhealthsecurity.org]
Rickettsia prowazekii treatment Tetracyclines tetracycline doxycycline Alternative: chloramphenicol List of antibiotics Rickettsia prowazekii vaccination Infection can also be prevented by vaccination.Vaccine developed by Herald R.[bacteria.cz]
PREVENTION Doxycycline prophylaxis may be used in epidemic situations. Prevention of epidemic typhus using delousing procedures is efficient, and should be implemented as soon as an outbreak is suspected.[antimicrobe.org]