We report on a patient with infantile glaucoma presenting at age 21 months with congestive heart failure due to a dysplastic arcade mitral valve necessitating valve replacement, and mildly hypoplastic left ventricular outflow tract and aortic arch. [ncbi.nlm.nih.gov]

Echocardiography revealed a flail anterior mitral valve leaflet with ruptured chordae and severe mitral regurgitation. The patient underwent urgent mitral valve replacement and tolerated the procedure well. [ncbi.nlm.nih.gov]

Progressive moderate mitral regurgitation in a children with Axenfeld-Rieger syndrome. The importance of cardiologic follow up. Arch Argent Pediatr 2016;114:e417–20. [19]. Gripp KW, Hopkins E, Jenny K, et al. [journals.lww.com]

She was still hearing his slight heart murmur, so she referred another echo. After talking more about A-R, she recommended a referral to see a geneticist at WVU. [daltonsstory.blogspot.com]

The patient had atrial septal defect, sensorineural hearing loss, polycystic ovaries, hirsutism, glomerulosclerosis, dental anomalies, and low intelligence. [ncbi.nlm.nih.gov]

This patient also had a younger sister of 5-year-old, who also suffered from blurred vision and had developmental anomalies in maxillary anterior teeth. 3 Discussion ARS was first described by German ophthalmologist Theodor Axenfeld in 1920 as featured [journals.lww.com]

The patient may complain of eyestrain, dry red eyes, headaches, transient blurred vision or diplopia, as well as neckache or backache. [medical-dictionary.thefreedictionary.com]

Case 1 A 56 year-old female (mother) had blurred vision complaints. Her best visual acuity was 20/25 in the right eye and 20/50 in the left eye. [scielo.br]

This patient also had a younger sister of 5-year-old, who also suffered from blurred vision and had developmental anomalies in maxillary anterior teeth. 3.  [ncbi.nlm.nih.gov]

Early recognition of dental anomalies aids in detection of the syndrome and prevents progressive loss of vision. This case report discusses the ocular, dental, and craniofacial findings and the overall management of the patient. [ncbi.nlm.nih.gov]