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Rotavirus


Presentation

  • Antibodies were present in most Chinese gamma globulins tested, including those collected in Shanghai before the 1982 epidemic, and absent from American reference pools.[ncbi.nlm.nih.gov]
  • The aim of this study was to investigate the presentation and complications of rotavirus compared to non-rotavirus gastroenteritis in UK children.[ncbi.nlm.nih.gov]
  • After about a week, one of the 2 identical infants presented inconsolable crying, vomiting, loose stools mixed with blood, and was diagnosed with bowel obstruction with intussusception. He was operated in urgency.[ncbi.nlm.nih.gov]
  • The present paper presents a brief overview of the variety of standard methods available, followed by suggestions for a systematic approach for routine rotavirus strain surveillance as well as for characterisation of incompletely typed rotavirus strains[ncbi.nlm.nih.gov]
  • We excluded articles that did not present overall impact estimates, including those that compared subnational populations or those that presented rotavirus strain–specific impact.[doi.org]
Sudden Infant Death Syndrome
  • Other reports have cited Kawasaki syndrome ( 33 ), sudden infant death syndrome ( 54 ), a hepatic abscess ( 21 ), pancreatitis ( 38 ), and diabetes ( 22 ) in association with rotavirus infection.[doi.org]
Renal Stone
  • Although ammonium acid urate (AAU) calculi are extremely rare renal stone components, it was recently found that many urinary tract calculi that cause post-renal renal failure in rotavirus (RV) gastroenteritis are AAU calculi.[ncbi.nlm.nih.gov]
Ataxia
  • The condition is characterized by disturbances of consciousness at onset and cerebellar signs and symptoms such as hypotonia, ataxia, dysmetria, and speech disorders, including mutism, slow speech, and dysarthria at convalescence.[ncbi.nlm.nih.gov]
  • Opsoclonus-myoclonus syndrome (OMS) is a rare neurologic disorder characterized by opsoclonus, myoclonus, ataxia and behavioral disturbance. In the pathogenesis, an autoimmune process with infectious or paraneoplastic trigger has been suggested.[ncbi.nlm.nih.gov]
Neurologic Manifestation
  • It is known that rotavirus gastroenteritis may be accompanied by neurological manifestations, including encephalitis/encephalopathy and seizures.[ncbi.nlm.nih.gov]
  • It is well recognised that rotavirus can cause signs and symptoms beyond the gastrointestinal tract, including neurological manifestations such as encephalopathy.[ncbi.nlm.nih.gov]
Slow Speech
  • The condition is characterized by disturbances of consciousness at onset and cerebellar signs and symptoms such as hypotonia, ataxia, dysmetria, and speech disorders, including mutism, slow speech, and dysarthria at convalescence.[ncbi.nlm.nih.gov]
Dysarthria
  • The condition is characterized by disturbances of consciousness at onset and cerebellar signs and symptoms such as hypotonia, ataxia, dysmetria, and speech disorders, including mutism, slow speech, and dysarthria at convalescence.[ncbi.nlm.nih.gov]
Speech Disorders
  • The condition is characterized by disturbances of consciousness at onset and cerebellar signs and symptoms such as hypotonia, ataxia, dysmetria, and speech disorders, including mutism, slow speech, and dysarthria at convalescence.[ncbi.nlm.nih.gov]

Workup

  • It was felt that the anemia was associated with the long-term use of NTZ, thus an anemia workup was not initiated but would have been considered if the blood count had not improved.[healio.com]
  • See Workup for more detail. Management In most cases, no medication is required for rotavirus infection. Instead, attention should be directed to appropriate fluid intake and other conservative measures.[emedicine.com]
Hyponatremia
  • Her normal serum sodium level indicates that this change can occur without hyponatremia.[ncbi.nlm.nih.gov]
Listeria Monocytogenes
  • Listeria monocytogenes only occasionally causes bacterial meningitis in immunocompetent children. We report a case of L. monocytogenes meningitis associated with rotavirus gastroenteritis.[ncbi.nlm.nih.gov]

Treatment

  • Furthermore, ondansetron reduced diarrhea episodes, most pronounced in children that had been sick for more than 3 days before treatment (p 0.028). CONCLUSION: Ondansetron may be a beneficial treatment for children with rotavirus gastroenteritis.[ncbi.nlm.nih.gov]
  • Two patients (cases 1 and 2) recovered completely without any specific treatments. One patient (case 3) died despite extensive treatments including a red blood cell transfusion and endoscopic hemostatic therapy.[ncbi.nlm.nih.gov]
  • Diarrheal Disease Treatment "Oral rehydration therapy is the best."[dx.doi.org]

Prognosis

  • What is the prognosis of a rotavirus infection? Rotavirus infection is a self-limited disease that resolves after three to nine days of symptoms. Rarely, severe dehydration accompanying rotavirus infection has led to death.[medicinenet.com]
  • Treatment and prognosis 7. Prevention 8. Epidemiology 9. In other animals 10.History - I suggest moving section ’Virology’ to the very first section.[en.wikiversity.org]

Etiology

  • Rotaviruses are members of the Reoviridae family of non-enveloped viruses and important etiologic agents of acute gastroenteritis in infants and young children.[ncbi.nlm.nih.gov]
  • Rotavirus is a nonenveloped, double-stranded, RNA virus belonging to the Reoviridae family and is the major etiological agent of viral gastroenteritis in young children and young animals.[ncbi.nlm.nih.gov]
  • Abstract Rotaviruses, a genus within the family Reoviridae, are among the most important etiological agents of severe diarrhoeal illness in humans and animals worldwide.[ncbi.nlm.nih.gov]
  • Abstract Rotaviruses represent 80% of recognized viral etiologies and 140 million cases of diarrhea per year.[ncbi.nlm.nih.gov]
  • INNATE IMMUNE RESPONSE SUSCEPTIBILITY OF ROTAVIRUS REPLICATION TO INTERFERONS VIRAL MEASURES TO COUNTERACT HOST CELL RESPONSES CONCLUDING REMARKS disclosure statement acknowledgments literature cited Abstract “Rotaviruses represent the most important etiological[annualreviews.org]

Epidemiology

  • To enable greater understanding of the overall epidemiologic situation, rotavirus types found in animals in Europe are described. In addition, rotavirus types occurring in children outside Europe are considered.[ncbi.nlm.nih.gov]
  • Common epidemiological settings for rotavirus infection among adults include endemic disease, epidemic outbreak, travel-related infection, and disease resulting from child-to-adult transmission.[ncbi.nlm.nih.gov]
  • epidemiology Rotavirus Infections/transmission Rotavirus Infections/veterinary* Rotavirus Infections/virology Sequence Alignment Sequence Homology, Nucleic Acid Turkeys/virology United States/epidemiology Viral Nonstructural Proteins/genetics Viral Nonstructural[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • In this review we intend to familiarise clinicians who primarily provide care for adult patients with the salient features of rotavirus pathophysiology, clinical presentation, epidemiology, treatment, and prevention.[ncbi.nlm.nih.gov]
  • Pathophysiology is complex and not fully understood Enterocytes at villous tips are initially infected; the virus binds surface carbohydrates and penetrates the cell membrane leading to transcription of viral RNA Damage to the mucosa leads to malabsorption[pathologyoutlines.com]
  • The pathophysiology of rotavirus diarrhea is clearly multifactoral.[doi.org]
  • Evo﹠Evo) talk 06:22, 27 April 2017 (UTC) Review by anonymous peer reviewer This review was submitted on 27 Apr 2017, and refers to this previous version of the article Content: The content is accurate and reflects the current state of rotavirus from a pathophysiology[en.wikiversity.org]
  • Group A rotavirus infection and age-dependent diarrheal disease in rats: a new animal model to study the pathophysiology of rotavirus infection. J Virol. 2002; 76 :41–57. [ PMC free article ] [ PubMed ] [ Google Scholar ] 97. Ramig RF.[ncbi.nlm.nih.gov]

Prevention

  • Both asymptomatic infection and person-to-person spread identified in this epidemic suggest that current emphasis on preventing waterborne transmission may not control the introduction of ADRV into new areas.[doi.org]
  • OBJECTIVES: To evaluate rotavirus vaccines approved for use (RV1, RV5, and LLR) for preventing rotavirus diarrhoea.[ncbi.nlm.nih.gov]
  • , Armenia & Ministry of Health of the Republic of Armenia, Yerevan, Armenia. 5 National Center of Disease Control and Prevention, Armenia Ministry of Health of the Republic of Armenia & Immunization and Epidemiology of Vaccine-Preventable Diseases, Yerevan[ncbi.nlm.nih.gov]
  • In a benefit-risk analysis, the prevented RVGE burden is weighed against the possible excess of intussusception. PURPOSE: The aim was to compare the estimated benefits and risks of Rotarix vaccination in France.[ncbi.nlm.nih.gov]

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