The aim of this study was to investigate the presentation and complications of rotavirus compared to non-rotavirus gastroenteritis in UK children. [ncbi.nlm.nih.gov]

We excluded articles that did not present overall impact estimates, including those that compared subnational populations or those that presented rotavirus strain–specific impact. [doi.org]

• Pain

  Abdominal pain Severe vomiting and diarrhoea Dehydration Death from untreated dehydration Common responses Mild diarrhoea or vomiting Abdominal pain Rare response Intussusception (bowel obstruction) [immune.org.nz]

  The most common symptoms of rotavirus are severe watery diarrhea, vomiting, fever, and/or abdominal pain. Symptoms usually start about 2 days after a person is exposed to rotavirus. Vomiting and watery diarrhea can last 3 to 8 days. [cdc.gov]

  Symptoms include: • Fever • Vomiting • Diarrhea • Abdominal pain Vomiting and watery diarrhea may last from 3 to 8 days in a child who is infected with rotavirus. [stopfoodborneillness.org]

  The infection can cause abdominal pain as well. In healthy adults, a rotavirus infection may cause only mild signs and symptoms or none at all. [mayoclinic.org]

  Caring for Your Child After Rotavirus Immunization For pain and fever, check with your doctor to see if you can give either acetaminophen or ibuprofen, and to find out the appropriate dose. [kidshealth.org]

• Asymptomatic

  […] children will have experienced infection on more than one occasion once someone has had a rotavirus infection they usually develop immunity, although it may be short lived second and subsequent infections with a strain previously encountered are often asymptomatic [gpnotebook.co.uk]

  In 15 pairs of infections, both episodes were asymptomatic. [nejm.org]

  Viral shedding begins before symptoms develop, and children may be shedding the virus for up to 48 h before they exhibit symptoms. 17 High rates of asymptomatic shedding of rotavirus have been reported in young children. [doi.org]

• Malnutrition

  […] factors that might contribute to the low vaccine efficacy, including passive transfer of maternal rotavirus antibodies, rotavirus seasonality, oral polio vaccine (OPV) administered concurrently, microbiome composition and concomitant enteric pathogens, malnutrition [ncbi.nlm.nih.gov]

  This may be because of other factors such as comorbidities and malnutrition. Intervention Delivery 3 oral rotavirus vaccines were evaluated, RV1 and RV5 (both approved in many countries). [methods.cochrane.org]

• El Salvador

  Favorites PDF Get Content & Permissions Free Decline in Rotavirus Hospitalizations and Health Care Visits for Childhood Diarrhea Following Rotavirus Vaccination in El Salvador Yen, Catherine; Armero Guardado, Julio A.; Alberto, Patricia; More The Pediatric [journals.lww.com]

  Apart from El Salvador, the G9P[8] virus had not previously been detected in Central America ( 2, 12 ). In this study it represented 7% of the HRV-positive cases in children attending the health care centers of Managua and Esteli. [doi.org]

• Weight Loss

  Signs of dehydration include: Increased thirst Less urine Dry mouth Fewer tears Weight loss See Signs of Dehydration in Infants & Children As dehydration becomes more severe, your child will become cranky and irritable, his eyes will appear sunken, and [healthychildren.org]

  Common symptoms include: Abdominal pain Diarrhea Nausea and vomiting Other symptoms may include: Chills, clammy skin, or sweating Fever Joint stiffness or muscle pain Poor feeding Weight loss The health care provider will look for signs of dehydration [nlm.nih.gov]

  If it becomes prolonged, complications can occur, including: Dehydration, potentially requiring treatment with IV fluids Blood in the stools, which can appear red or black Weight loss Lethargy Low blood pressure Rapid pulse Dizziness Low amounts of [verywellhealth.com]

• Cough

  Prevention includes observing good respiratory-hygiene (cough and sneeze etiquette) and hand-hygiene (frequent, thorough handwashing) measures. [tripprep.com]

  [+] more Pertussis (Whooping Cough) Pertussis (Whooping Cough) Pertussis (Whooping Cough) is a highly contagious bacterial respiratory disease. [immunizeforgood.com]

  Adverse Reactions: Reactions to the vaccine are uncommon – some children developed diarrhoea, vomiting, fever, runny nose, cough or wheeze and ear infection in the period after vaccination but the incidence was around the same as children not vaccinated [stagnessurgery.com.au]

  Occasionally it can be passed on through droplets coughed or sneezed into the air. Older children and adults can be infected without showing the usual symptoms. This can help rotavirus infections to be passed on in a community. [vk.ovg.ox.ac.uk]

• Diarrhea

  Diarrhea-Related Deaths Figure 1. Figure 1. Number of Diarrhea-Related Deaths among Children 59 Months of Age or Younger from July 2002 through May 2009 in Mexico, According to Age Group. [doi.org]

  001.0–005.9 (excluding 003.2) and 008.0–008.5; parasitic intestinal disease, 006.0–007.9 (excluding 006.3–006.6); presumed infectious diarrhea, 009.0–009.3; presumed noninfectious diarrhea, 558.9; and diarrhea not otherwise specified, 787.91. [pediatrics.aappublications.org]

• Abdominal Pain

  Abdominal pain Severe vomiting and diarrhoea Dehydration Death from untreated dehydration Common responses Mild diarrhoea or vomiting Abdominal pain Rare response Intussusception (bowel obstruction) [immune.org.nz]

  The most common symptoms of rotavirus are severe watery diarrhea, vomiting, fever, and/or abdominal pain. Symptoms usually start about 2 days after a person is exposed to rotavirus. Vomiting and watery diarrhea can last 3 to 8 days. [cdc.gov]

  Symptoms include: • Fever • Vomiting • Diarrhea • Abdominal pain Vomiting and watery diarrhea may last from 3 to 8 days in a child who is infected with rotavirus. [stopfoodborneillness.org]

  The virus can cause severe watery diarrhea, vomiting, fever, and abdominal pain. Children who get rotavirus disease can become severely dehydrated and need to be hospitalized and can even die. [health.hawaii.gov]

• Acute Diarrhea

  For centuries, acute diarrhea has been a major worldwide cause of death in young children, and until 1973, no infectious agents could be identified in about 80% of patients admitted to hospital with severe dehydrating diarrhea. [ncbi.nlm.nih.gov]

  Abstract For centuries, acute diarrhea has been a major worldwide cause of death in young children, and until 1973, no infectious agents could be identified in about 80% of patients admitted to hospital with severe dehydrating diarrhea. [doi.org]

• Abdominal Cramps

  The affected person may also have headache, fever and abdominal cramps (“stomach ache”). [certest.es]

  Spread by faecal-oral transmission, rotavirus infection in adults typically manifests with nausea, malaise, headache, abdominal cramping, diarrhoea, and fever. Infection can also be symptomless. [ncbi.nlm.nih.gov]

  Signs and Symptoms Kids with a rotavirus infection have fever, nausea, and vomiting, often followed by abdominal cramps and frequent, watery diarrhea. Kids may also have a cough and runny nose. [kidshealth.org]

• Failure to Thrive

  We describe three infants, two with failure to thrive, who had dehydration and diarrhea within 1 month after their first or second rotavirus immunization and subsequently received a diagnosis of severe combined immunodeficiency. [ncbi.nlm.nih.gov]

  A child with severe combined immunodeficiency (SCID), a group of rare, life-threatening genetic disorders that affect the body’s ability to fight infection and often result in chronic diarrhea and failure to thrive. [babycenter.com]

• Decrease in Height

  During RVs infections in weaned pigs, there is evidence of disruption of the barrier function as evidenced by the decreased villus height and crypt depth, lower levels of IgA, IL-4, and mucin 1 as well a reduced transcription of ZO-1, occludin, and Bcl [doi.org]

• Fussiness

  Symptoms of dehydration include: decreased urination dry mouth and throat feeling dizzy when standing up crying with few or no tears and unusual sleepiness or fussiness. Rotavirus disease is most common in infants and young children. [cdc.gov]

  […] usually lasting three to eight days Fever Abdominal pain Loss of appetite Dehydration (symptoms of dehydration include decreased urination, dry mouth and throat, feeling dizzy when standing up, crying with few or no tears, and unusual sleepiness or fussiness [whattoexpect.com]

  So after the first dose, watch for symptoms such as periods of intense abdominal pain with uncontrollable crying; vomiting; blood or mucus in the poop; and seeming weak, drowsy, or fussy. Date reviewed: March 2019 [kidshealth.org]

• Irritability

  When recovering from rotavirus, a bland diet that avoids foods that might irritate your child's stomach is advised. [livestrong.com]

  Signs of severe dehydration include irritability, lethargy, sunken eyes, sunken soft spot (in infants), dry mouth and tongue, less frequent bathroom trips and dry diapers for more than a couple of hours. [verywellhealth.com]

  Children can also experience: vomiting severe fatigue a high fever irritability dehydration abdominal pain Dehydration is the greatest concern in children. [healthline.com]

  Parents were significantly more worried if their child was tearful (p = 0.006) or irritable (p CONCLUSION: Objective health status of the child did not influence the emotional, social or economic burden, whereas the parents' subjective perception of the [ncbi.nlm.nih.gov]

• Perseveration

  Expected Retinitis Pigmentosa Cure The cure of retinitis pigmentosa, or other degenerative eye diseases for that matter, has always been a challenge, but it looks like the perseverance of researchers will finally come to fruition very soon. [irisvision.com]

It was felt that the anemia was associated with the long-term use of NTZ, thus an anemia workup was not initiated but would have been considered if the blood count had not improved. [healio.com]

See Workup for more detail. Management In most cases, no medication is required for rotavirus infection. Instead, attention should be directed to appropriate fluid intake and other conservative measures. [emedicine.com]

Furthermore, ondansetron reduced diarrhea episodes, most pronounced in children that had been sick for more than 3 days before treatment (p = 0.028). CONCLUSION: Ondansetron may be a beneficial treatment for children with rotavirus gastroenteritis. [ncbi.nlm.nih.gov]

Treatment Gastroenteritis is a common illness which can be particularly serious in young children. No specific antiviral treatment is available and antibiotics are not effective. [sahealth.sa.gov.au]

Traditional treatments for a rotavirus infection If your child develops rotavirus, she may not be able to attend daycare or school while ill. [childrenshospital.org]

Diarrheal Disease Treatment "Oral rehydration therapy is the best." [biomedcentral.com]

Prognosis Except for mild cases or sectorial RP, most cases progress to legal blindness (visual acuity < 1/20 and visual field < 5 degrees). The documents contained in this web site are presented for information purposes only. [orpha.net]

What is the prognosis of a rotavirus infection? Rotavirus infection is a self-limited disease that resolves after three to nine days of symptoms. Rarely, severe dehydration accompanying rotavirus infection has led to death. [medicinenet.com]

Outlook / Prognosis What’s the outlook for children with rotavirus? Most children recover from rotavirus without long-term health effects. Symptoms last about a week. [my.clevelandclinic.org]

Rotaviruses are members of the Reoviridae family of non-enveloped viruses and important etiologic agents of acute gastroenteritis in infants and young children. [ncbi.nlm.nih.gov]

It is the most important etiologic agent globally of diarrhea in children under 5 years of age (2). Two globally licensed vaccines (Rotarix and RotaTeq) have been developed for the control of human RVA (3). [mra.asm.org]

To enable greater understanding of the overall epidemiologic situation, rotavirus types found in animals in Europe are described. In addition, rotavirus types occurring in children outside Europe are considered. [ncbi.nlm.nih.gov]

In this review we intend to familiarise clinicians who primarily provide care for adult patients with the salient features of rotavirus pathophysiology, clinical presentation, epidemiology, treatment, and prevention. [ncbi.nlm.nih.gov]

Pathophysiology is complex and not fully understood Enterocytes at villous tips are initially infected; the virus binds surface carbohydrates and penetrates the cell membrane leading to transcription of viral RNA Damage to the mucosa leads to malabsorption [pathologyoutlines.com]

The pathophysiology of rotavirus diarrhea is clearly multifactoral. [doi.org]

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Rotavirus is a major cause of nonbacterial gastroenteritis, especially in infants and very young children (6 months-2 years of [mayocliniclabs.com]

Evo﹠Evo) talk 06:22, 27 April 2017 (UTC) Review by anonymous peer reviewer This review was submitted on 27 Apr 2017, and refers to this previous version of the article Content: The content is accurate and reflects the current state of rotavirus from a pathophysiology [en.wikiversity.org]

OBJECTIVES: To evaluate rotavirus vaccines approved for use (RV1, RV5, and LLR) for preventing rotavirus diarrhoea. [ncbi.nlm.nih.gov]

PREVENTION Unlike other types of diarrhoea, improving hygiene does not prevent rotavirus infection. Also, antibiotics and other drugs cannot cure rotavirus. [gavi.org]