Presentation
The aim of this study was to investigate the presentation and complications of rotavirus compared to non-rotavirus gastroenteritis in UK children. [ncbi.nlm.nih.gov]
We excluded articles that did not present overall impact estimates, including those that compared subnational populations or those that presented rotavirus strain–specific impact. [doi.org]
Entire Body System
- Increased Susceptibility to Infections
Neonates have an increased susceptibility to infections, particularly those caused by intracellular pathogens, leading to high morbidity and mortality rates. [ncbi.nlm.nih.gov]
Neurologic
- Neurologic Manifestation
It is known that rotavirus gastroenteritis may be accompanied by neurological manifestations, including encephalitis/encephalopathy and seizures. [ncbi.nlm.nih.gov]
- Myoclonus
Opsoclonus-myoclonus syndrome (OMS) is a rare neurologic disorder characterized by opsoclonus, myoclonus, ataxia and behavioral disturbance. In the pathogenesis, an autoimmune process with infectious or paraneoplastic trigger has been suggested. [ncbi.nlm.nih.gov]
Workup
It was felt that the anemia was associated with the long-term use of NTZ, thus an anemia workup was not initiated but would have been considered if the blood count had not improved. [healio.com]
See Workup for more detail. Management In most cases, no medication is required for rotavirus infection. Instead, attention should be directed to appropriate fluid intake and other conservative measures. [emedicine.com]
Microbiology
- Giardia Lamblia
Bacterial pathogens, Giardia lamblia, and Norwalk virus were excluded as responsible agents. Rotavirus should be looked for as a cause of waterborne outbreaks. [ncbi.nlm.nih.gov]
- Listeria Monocytogenes
Listeria monocytogenes only occasionally causes bacterial meningitis in immunocompetent children. We report a case of L. monocytogenes meningitis associated with rotavirus gastroenteritis. [ncbi.nlm.nih.gov]
Treatment
Furthermore, ondansetron reduced diarrhea episodes, most pronounced in children that had been sick for more than 3 days before treatment (p = 0.028). CONCLUSION: Ondansetron may be a beneficial treatment for children with rotavirus gastroenteritis. [ncbi.nlm.nih.gov]
Diarrheal Disease Treatment "Oral rehydration therapy is the best." [doi.org]
Prognosis
Prognosis Except for mild cases or sectorial RP, most cases progress to legal blindness (visual acuity < 1/20 and visual field < 5 degrees). The documents contained in this web site are presented for information purposes only. [orpha.net]
What is the prognosis of a rotavirus infection? Rotavirus infection is a self-limited disease that resolves after three to nine days of symptoms. Rarely, severe dehydration accompanying rotavirus infection has led to death. [medicinenet.com]
According to some studies, individuals with adRP have the best prognosis, with the majority of those younger than age 30 years having a visual acuity of 20/30 or better. [institut-vision.org]
Etiology
Rotaviruses are members of the Reoviridae family of non-enveloped viruses and important etiologic agents of acute gastroenteritis in infants and young children. [ncbi.nlm.nih.gov]
It is the most important etiologic agent globally of diarrhea in children under 5 years of age (2). Two globally licensed vaccines (Rotarix and RotaTeq) have been developed for the control of human RVA (3). [mra.asm.org]
Epidemiology
To enable greater understanding of the overall epidemiologic situation, rotavirus types found in animals in Europe are described. In addition, rotavirus types occurring in children outside Europe are considered. [ncbi.nlm.nih.gov]
Pathophysiology
In this review we intend to familiarise clinicians who primarily provide care for adult patients with the salient features of rotavirus pathophysiology, clinical presentation, epidemiology, treatment, and prevention. [ncbi.nlm.nih.gov]
Pathophysiology is complex and not fully understood Enterocytes at villous tips are initially infected; the virus binds surface carbohydrates and penetrates the cell membrane leading to transcription of viral RNA Damage to the mucosa leads to malabsorption [pathologyoutlines.com]
Evo﹠Evo) talk 06:22, 27 April 2017 (UTC) Review by anonymous peer reviewer This review was submitted on 27 Apr 2017, and refers to this previous version of the article Content: The content is accurate and reflects the current state of rotavirus from a pathophysiology [en.wikiversity.org]
Pathophysiology Rotavirus, like other viruses that cause enteritis, primarily infects the cells of the small intestinal villi, especially those cells near the tips of the villi. [emedicine.com]
Prevention
OBJECTIVES: To evaluate rotavirus vaccines approved for use (RV1, RV5, and LLR) for preventing rotavirus diarrhoea. [ncbi.nlm.nih.gov]
Both asymptomatic infection and person-to-person spread identified in this epidemic suggest that current emphasis on preventing waterborne transmission may not control the introduction of ADRV into new areas. [doi.org]