Presentation
A very rare variant of lobular panniculitis, presenting with numerous large subcutaneous lesions, affecting children and occurring within the first 12 months of age. Lipogranulomatosis Subcutanea. First described by M. [accessanesthesiology.mhmedical.com]
Keywords: Panniculitis; Lipogranulomatosis subcutanea; Granulomatous disorders; Treatment Case Report A 70-year-old female patient presented with a 10 week history of subcutaneous nodules on trunk and extremities. [symbiosisonlinepublishing.com]
Alpha1-antitrypsin deficiency panniculitis – tends to involve proximal extremities, ulceration and drainage of oily brown exudate is frequently observed, associated systemic manifestations (emphysema and cirrhosis) are usually present, and serum alpha1 [visualdx.com]
This volume includes the reports of several hundreds of speakers from all over the world as presented during the congress or delivered 6 weeks later. [books.google.it]
Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis [books.google.es]
Entire Body System
- Candidiasis
Functional asplenia has complicated the course of autoimmune diseases other than SLE, such as candidiasis endocrinopathy syndrome and alopecia areata [5]. [academic.oup.com]
Functional asplenia has complicated the course of autoimmune diseases other than SLE, such as candidiasis endocrinopathy syndrome and alopecia areata [ 5 ]. [rheumatology.oxfordjournals.org]
Childhood, Bullous Diabeticorum, Bullous Disorders, Bullous Pemphigoid, Burn, Buruli Ulcer, Buschke-Ollendorff Syndrome, Cafe-Au-Lait Spots, Caffey's Syndrome, Calcifying Epithelioma, Calcinosis Cutis And Osteoma Cutis, Callus, Campbell De'morgan Spot, Candidiasis [google.com]
- Collapse
Rothes finally collapsed with Paul Young tucking away the second before Aaron McKenna and another from Booth in added time gave the scoreline a flattering sheen. Rothes II said it received consent for 18 turbines and 45 mw in January 2010. [freethesaurus.com]
Jaw & Teeth
- Sore Mouth
[…] vy二氏病 routes of infection 傳染途徑 routine urinalysis 常規尿分析 Rowell syndrome Rowell氏症候群 Rowland's disease Rowland氏病 Royal Free disease Royal Free病 royal jelly 蜂王漿 royal malady 富貴病 rubber 橡皮 rubber bandage 橡皮繃帶 rubber sore mouth 橡皮性口腔瘡 rubber workers 橡膠職工 rubbing [sheethub.com]
Eyes
- Roth's Spots
▲ Rotavirus Infections rotavirus vaccine live oral rotavirus vaccine, live, oral rotaviruses Rotch Rotch sign Rotch, Thomas M. rote learning rotenone Roth Roth spot Roth spots Roth, Moritz Roth, Vladimir K. Roth, W. [medical-dictionary.thefreedictionary.com]
Roth's spots In bacterial endocarditis and other retinal hemorrhagic conditions, a round white spot surrounded by hemorrhage (secondary to microemboli in endocarditis). [wikem.org]
Skin
- Subcutaneous Nodule
On admission, subcutaneous nodules were recognized on bilateral upper arms, abdomen, gluteal regions and thighs. None of these nodules were associated with local heat or pain. [unboundmedicine.com]
On examination we observed multiple painless subcutaneous nodules on her back, right breast, left arm and shoulder and left thigh. These nodules were initially skin-colored, later bluish with some telangiectasias and skin atrophy (Figure1). [symbiosisonlinepublishing.com]
Erythema nodosum Erythematous condition (disorder) Inflammatory disease of subcutaneous fat including noninfectious granuloma (disorder) Subcutaneous nodule Vasculitis of the skin Name: Lipogranulomatosis subcutanea of Rothmann and Makai (disorder) See [snomedbrowser.com]
Definition / general Subcutaneous nodules on the trunk and extremities which undergo spontaneous involution, and are not associated with systemic symptoms Microscopic (histologic) description Lipogranulomas of subcutis, but not in crops Differential diagnosis [pathologyoutlines.com]
- Skin Lesion
Steroid treatment was effective on both skin lesions and mononeuropathy. Steroid treatment was effective on both skin lesions and mononeuropathy. [unboundmedicine.com]
Vascular access placement and fixation can be very difficult because of skin lesions. [accessanesthesiology.mhmedical.com]
Skin lesions were subcutaneous, elastic, hard, walnut-sized nodules with slight erythema arranged in on arc on the chest and abdomen. [webview.isho.jp]
Not only is it crucial to diagnose skin pre-cancer or skin cancer at an early stage when it is curable, but it is also important to improve the clinical diagnosis of suspected skin lesions so as to avoid unnecessary skin biopsies. [google.com]
Neurologic
- Mononeuropathy
By those findings, she was diagnosed as Rothmann-Makai syndrome associated with mononeuropathy. Steroid treatment was effective on both skin lesions and mononeuropathy. Steroid treatment was effective on both skin lesions and mononeuropathy. [unboundmedicine.com]
Workup
Serum
- Anisopoikilocytosis
A peripheral blood smear revealed anisopoikilocytosis and numerous Howell–Jolly bodies, indicating functional hyposplenism. [academic.oup.com]
- Thrombocytosis
Economopoulos Accepted: 02 September 2005 Published: 18 October 2005 Sir, A 27-yr-old woman was referred for evaluation of mild anaemia, leucocytosis and thrombocytosis. [academic.oup.com]
Economopoulos Published: 18 October 2005 Accepted: 02 September 2005 S ir, A 27-yr-old woman was referred for evaluation of mild anaemia, leucocytosis and thrombocytosis. [rheumatology.oxfordjournals.org]
- Howell-Jolly Bodies
A peripheral blood smear revealed anisopoikilocytosis and numerous Howell–Jolly bodies, indicating functional hyposplenism. [academic.oup.com]
- Angiotensin Converting Enzyme Decreased
Angiotensin-converting enzyme decreased with 5.8 U/l (normal range: 20-70 U/l). Alpha -1-antitrypsin and syphilis serology normal or negative. Microbiological swabs were taken from the right breast wound and the right upper arm. [symbiosisonlinepublishing.com]
Other Pathologies
- Lymphocytic Infiltrate
Microscopic examination of skin biopsy showed lipolysis and diffuse lymphocyte infiltration (panniculitis) and perivascular lymphocyte infiltration was also observed. [unboundmedicine.com]
In the first stage, there is acute inflammation of the fat lobules with fat cell degeneration accompanied by an infiltrate of neutrophils, lymphocytes and macrophages. [academic.oup.com]
Other ECG Findings
- Ischemic Changes
We concluded that this mononeuropathy may be induced by a ischemic change which may be caused by panniculitis. [unboundmedicine.com]
Biopsy
- Foam Cell
Finally, the foam cells are replaced by fibroblasts. The first two histological stages correspond to clinically apparent induration, while in the third stage atrophy of the skin may develop. There are no diagnostic laboratory findings. [academic.oup.com]
Treatment
Oral treatment with non-steroidal ibuprofen, short course of prednisolone (80 mg/d) tapered down, and pantoprazole was initiated with rapid improvement. [symbiosisonlinepublishing.com]
Steroid treatment was effective on both skin lesions and mononeuropathy. Steroid treatment was effective on both skin lesions and mononeuropathy. [unboundmedicine.com]
Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. [books.google.es]
The cause is unknown and there is no effective treatment. [jamanetwork.com]
Prognosis
Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis [books.google.es]
The prognosis depends upon the severity of the renal disease http://www.geocities.com/SoHo/Gallery/6 ... ulitis.htm ............ [lymphedemapeople.com]
These evaluations and resulting analyses can be viewed, collated, and cross referenced in an easy and efficient manner such that time is minimized, data accurately recorded and aggregated for efficient and accurate assessments and prognosis made. [google.com]
Etiology
Erythema induratum of Bazin – occurs on the posterior aspects of the lower extremities, and ulceration is frequent; an etiologic relationship with tuberculosis is often demonstrated; histopathology reveals lobular panniculitis with vasculitis involving [visualdx.com]
Pathogenesis and histological features The etiology and pathogenesis of erythema nodosum are unknown. [basicmedicalkey.com]
DOI: http://dx.doi.org/10.15226/2378-1726/3/3/00129 Abstract Lipogranulomatosis subcutaneous (Rothmann-Makai) is a rare localized non-infectious panniculitis of unknown etiology. [symbiosisonlinepublishing.com]
Eger et al. 1943 Etiology of varicose veins from an anatomic aspect, based on a dissection of thirty-eight adult cadavers Wégria et al. 1951 Effect of nitroglycerine on the cardiovascular system of normal persons JP2002233331A ( ja ) 2002-08-20 血行障害の改善作用 [patents.google.com]
Todo T, Gallo A, Berumen J, Feinberg E, Melcher M, Bonham C, Busque S, Concepcion W, Esquivel CO, Am J Transplant, 1/1/2014 Etiology of liver disease affects post-liver transplantation survival among hepatocellular carcinoma patients. [doximity.com]
Epidemiology
Epidemiology. The true incidence of erythema nodosum is unknown. In a retrospective review of the histopathology of 329 cases of panniculitis, erythema nodosum was by far the most common diagnosis (29%) [1]. [plasticsurgerykey.com]
Resistant hypertension -- its identification and epidemiology. Nat Rev Nephrol 2013 ;9: 51 - 58 [Erratum, Nat Rev Nephrol 2013;9:492.] 2. Kumbhani DJ, Steg PG, Cannon CP, et al. [nejm.org]
The politics of participatory epidemiology: Technologies, social media and influenza surveillance in the US. Health Policy and Technology 2017;6(2):192 CrossRef Shrank WH. Primary Care Practice Transformation and the Rise of Consumerism. [jmir.org]
Pathophysiology
Saint's triad The coexistence of hiatal hernia, gallbladder disease, and diverticulosis in a patient; named after Saint, a South African surgeon; no pathophysiologic basis for the coexistence of all three processes, emphasizing that more than one disease [wikem.org]
Prevention
0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis [codelay.com]
Prevention and management of infection in children with sickle cell anaemia. Paediatr Drugs 2001 ; 3 : 793 –801. 4 Kalhs P, Panzer S, Kletter K et al. Functional asplenia after bone marrow transplantation. [academic.oup.com]
A simple hygienic program using a sudsing detergent has in many instances prevented or eliminated a cutaneous disorder, and hence we frequently request an amputee to follow a given routine. [oandplibrary.org]