Presentation
The presentation in adulthood with rupture of the aneurysm and the successful surgical treatment of both abnormalities are unusual. [ncbi.nlm.nih.gov]
Entire Body System
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Fishing
Healthy foods include fruits, vegetables, whole-grain breads, beans, lean meats, fish, and low-fat dairy products. Your healthcare provider or dietitian can help you create a meal plan to help control high blood pressure or cholesterol. [drugs.com]
Gastrointestinal
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Regurgitation
The patient had blue sclerae (Figure 3 ), hypertension, and mitral regurgitation (New York Heart Association class 2), and had sustained repeated fractures of the extremities such as left elbow joint and left ankle joint prior to puberty. [bmcneurol.biomedcentral.com]
Musculoskeletal
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Hyperlaxity
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder, caused by abnormalities in type 1 collagen, and is characterized by bone fragility and other extraskeletal features, including hearing loss, blue sclerae, dentinongenesis imperfecta and hyperlaxity [bmcneurol.biomedcentral.com]
Eyes
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Blue Sclera
She had blue sclerae, a history of several fractures of the extremities, and a family history of bone fragility and blue sclerae in her son. According to these findings, she was diagnosed with OI type 1. [bmcneurol.biomedcentral.com]
Ears
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Normal Hearing
Completely normalized hearing was found in five patients at 3-6 months follow-up, whereas two cases noticed a partial loss and one made no recovery. [ncbi.nlm.nih.gov]
Neurologic
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Quadriplegia
The patient had residual moderate disturbance of consciousness and quadriplegia before transfer for rehabilitation. [ncbi.nlm.nih.gov]
Workup
Workup for Patients with Suspected Nontraumatic SAH Figure 1. Algorithm for evaluating patients with suspected nontraumatic SAH. [aafp.org]
The workup may include: Physical exam - The physician checks blood pressure, feels the body for masses and listens to blood flow sounds. [innerbody.com]
See Workup for more detail. [emedicine.medscape.com]
Serum
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Macrocytic Anemia
At a referring institution, he showed evidence of macrocytic anemia (white blood cell count, 9,000/μL; red blood cell count, 104 10(4)/μL; hemoglobin, 4.0 g/dL; hematocrit, 12.2%; and platelet count, 26.6 10(4)/μL). [ncbi.nlm.nih.gov]
Treatment
Those patients suffering a seizure were identified prospectively at various time points after randomization, as follows: before treatment; after treatment and before discharge; after discharge to 1 year; and annually thereafter. [ncbi.nlm.nih.gov]
The rationale for treatment selection is not known, and no correction was made for associated biases of non-random assignment to treatment. [jnis.bmj.com]
Prognosis
Abstract Subpial hematoma is a rare type of intracranial hemorrhage with a poor prognosis. [ncbi.nlm.nih.gov]
The prognosis of patients with early reruptured aneurysms is discouraging. A rerupture of an aneurysm with active bleeding is extremely rare, and the mechanisms involved remain unclear. [ajnr.org]
Therefore, early diagnosis and proper treatment are crucial for a good prognosis. [skullbaseinstitute.com]
Etiology
The etiology may be of local, systemic, psychological, or occupational in nature. However, the major etiological factor is psychological. [ncbi.nlm.nih.gov]
Loculated intracranial aneurysms: angiography and possible etiology. Radiology 1974 ; 113 : 101 Gailloud P, Murphy KJ. Rupture of cerebral aneurysm during angiography. N Engl J Med 1999 ; 340 : 1442 Yousem DM, Trinh BC. [ajnr.org]
The etiology of sleep bruxism seems to be centrally mediated (23). It occurs mostly during a switch from deep sleep to shallow sleep (24). [frontiersin.org]
Pathophysiology The pathogenesis of cerebral aneurysms is related inherently to structural aberrations of the cerebrovasculature, although the etiology of these abnormalities may be diverse. [emedicine.medscape.com]
Size Small, 15 mm Large, 15–25 mm Giant, 25–50 mm Supergiant, 50 mm Shape Berry: Most common (95%); berry-shaped aneurysm with a neck or stem Sacular: Any aneurysm with a sacular outpouching Fusiform: Outpouching of an arterial wall but with no stem Etiology [medical-dictionary.thefreedictionary.com]
Epidemiology
BACKGROUND: To review the epidemiology of sporadic ruptured cerebral aneurysm. [ncbi.nlm.nih.gov]
Aneurysm subarachnoid hemorrhage outcomes epidemiology national inpatient sample unruptured aneurysm hemorrhage coil statistics Statistics from Altmetric.com Aneurysm subarachnoid hemorrhage outcomes epidemiology national inpatient sample unruptured aneurysm [jnis.bmj.com]
Epidemiology of subarachnoid hemorrhage in Finland from 1983 to 1985. Stroke. 1991. 22: 848-53 23. Szikora I, Berentei Z, Kulcsar Z, Marosfoi M, Vajda ZS, Lee W. [surgicalneurologyint.com]
Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening. Lancet Neurol. 13, 393–404 (2014). 8. Nieuwkamp, D. J. et al. [nature.com]
"Epidemiology and genetics of intracranial aneurysms". European Journal of Radiology. 82 (10): 1598–605. doi:10.1016/j.ejrad.2012.12.026. PMID 23399038. [en.wikipedia.org]
Pathophysiology
Factors predisposing to aneurysm rupture such as hemodynamic changes in the parent vessel, pathophysiology of the aneurysm wall, size and location of the aneurysm, age, sex aid blood pressure of the patient are thought to be important contributing factors [ir.ymlib.yonsei.ac.kr]
Blister aneurysms were not considered in this series since they differ both morphologically and histologically from saccular aneurysms and likely represent a distinct pathophysiology. [surgicalneurologyint.com]
The incidence and pathophysiology of hyponatraemia after subarachnoid haemorrhage. Clin Endocrinol (Oxf). 2006 Mar. 64(3):250-4. [Medline]. Sluzewski M, van Rooij WJ. [emedicine.medscape.com]
Recent genome-wide association studies (GWAS) provide molecular evidence for shared biological function and activities (pathophysiology) of these aneurysms. [ninds.nih.gov]
Prevention
The rationale of this emergency procedure is to prevent early rerupture and also to prevent neurological ischaemic consequences of the subarachnoid haemorrhage likely to develop in the first week after a rupture. [ncbi.nlm.nih.gov]
An aneurysm that has not burst can be managed or treated to prevent it from rupturing. An aneurysm can happen anywhere in your brain. They most commonly form between the brain and the base of the skull. [drugs.com]