Presentation
It is associated with progressive pulmonary disability, irreversible lung damage, and mortality in some occupational settings. 1-5 Patients often present with intermittent chills, fever, cough, and shortness of breath that begin four to eight hours after [labcorp.com]
In addition, numerous precipitin arcs were present in the sera of the symptomatic but not the asymptomatic subjects by antigen-antibody crossed immunoelectrophoresis. [ncbi.nlm.nih.gov]
Fink Published in The Journal of allergy and clinical immunology 1988 DOI: 10.1016/0091-6749(88)90998-0 In the present study, cellular and humoral responses to Faenia rectivirgula antigens were evaluated in seven subjects, members of a family who lived [semanticscholar.org]
Hypersensitivity Screening Antigens: Thermoactinomyces vulgaris (TH3), Candida (CAND), Pigeon serum (EB1), Aureobasidium pullulans (TH5), Aspergillus polyvalent mix (M1) Reference Interval Negative Interpretive Data Precipitating IgG antibodies are often present [nationaljewish.org]
Entire Body System
- Chills
It is associated with progressive pulmonary disability, irreversible lung damage, and mortality in some occupational settings. 1-5 Patients often present with intermittent chills, fever, cough, and shortness of breath that begin four to eight hours after [labcorp.com]
These are some of the signs and symptoms: shortness of breath, a dry irritating cough, a sudden general feeling of sickness, fever and chills, a rapid heart rate, and rapid breathing. [ccohs.ca]
Clinically, extrinsic allergic alveolitis is characterized by intermittent episodes of chills, fever, cough, and shortness of breath occurring 4 to 8 hours after inhalation of the specific sensitizing agent. [allallergy.net]
Fever, chills, dyspnea, leukocytosis may occur 4-6 hours after exposure and eventually resolve; symptoms and signs may recur on re-exposure. CXR: Acute - normal to reticulonodular pattern; Chronic - progressive fibrosis, honeycombing. [lumen.luc.edu]
- Asymptomatic
This antigen fraction reacted with the sera of all 15 farmer's lung patients and 20 asymptomatic farmers with circulating anti-M. faeni antibodies. [ncbi.nlm.nih.gov]
However, a positive test does not always indicate active disease since asymptomatic individuals may develop precipitins without any features of hypersensitivity. [labguide.fairview.org]
- Disability
It is associated with progressive pulmonary disability, irreversible lung damage, and mortality in some occupational settings. 1-5 Patients often present with intermittent chills, fever, cough, and shortness of breath that begin four to eight hours after [labcorp.com]
- Fatigue
A boy and a girl, 10 weeks and 3 years of age, respectively, were admitted with low temperature, dry cough, fatigue and weight loss. [allallergy.net]
Musculoskeletal
- Myopathy
[…] resistance to phagocytosis, and host substrate utilization New information on changes in body weight Recent findings on fibrocoxib and diclofenac Expanded and reorganized coverage of critical care New material on inborn errors of metabolism and acquired myopathies [books.google.it]
Skin
- Erythema
Some manifestations to watch for: - Myocardial involvement (possible conduction disturbances) - Uveitis - Cranial nerve VII involvement - Erythema nodosa PFTs: Decreased volumes, compliance, DLCO, hypoxemia. [lumen.luc.edu]
Psychiatrical
- Suggestibility
It is suggested that a common polysaccharide antigen may exist on the surface membranes of M. pneumoniae and M. faeni. [ncbi.nlm.nih.gov]
It is suggested that farmer's lung may involve a cytotoxic type II reaction, in which glycoproteins adsorbed to tissue cells react with IgG, IgA and IgM immunoglobulins in the presence of complement, causing cellular damage. [wwww.unboundmedicine.com]
Useful For Suggests clinical disorders or settings where the test may be helpful Evaluation of patients suspected of having hypersensitivity pneumonitis induced by exposure to Micropolyspora faeni Method Name A short description of the method used to [mayomedicallaboratories.com]
Urogenital
- Incontinence
His interests are in incontinence in the elderly, the effects of medication and co-morbidity on continence status and the epidemiology and aetiology of incontinence in the elderly. [books.google.ro]
- Urinary Incontinence
He has developed and maintained an academic and clinical interest in urinary incontinence, alongside his clinical and educational responsibilities. [books.google.ro]
Neurologic
- Confusion
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances IgG antibodies to Micropolyspora faeni, Thermoactinomyces vulgaris, or Aspergillus [mayomedicallaboratories.com]
The symptoms are sometimes confused with pneumonia. Sub-Acute Farmer's Lung Sub-acute Farmer's Lung is more common than acute Farmer's Lung but it is less intense and more difficult to notice. [ccohs.ca]
- Burning Sensation
I started getting this tickiling and burning in my chest and throat about two months ago with tightness in chest and shortness of breath. i have this cold, almost painful burning sensation when i breathe through my nose or mouth. [medhelp.org]
Workup
Microbiology
- Saccharopolyspora Rectivirgula
REPUBLIC OF) Saccharopolyspora rectivirgula Antibody:임의농도:검사시점:혈청:순위척도: pt-BRPortuguese (BRAZIL) Saccharopolyspora rectivirgula Ac:ACnc:Pt:Soro:Ord: ru-RURussian (RUSSIAN FEDERATION) Saccharopolyspora rectivirgula Ат:PrThr:ТчкВрм:Сыв:Пор: es-ARSpanish [loinc.org]
Name: Saccharopolyspora rectivirgula (Krassilnikov and Agre 1964) Korn-Wendisch et al. 1989 emend. [dsmz.de]
METHODS: Determination of precipitins and specific IgG to Aspergillus fumigatus, Saccharopolyspora rectivirgula and Thermoactynomices vulgaris in the three previously mentioned groups. [occupationalasthma.com]
Treatment
A similar material was obtained from a cell-wall preparation by treatment with lysozyme. [ncbi.nlm.nih.gov]
Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.it]
Cell walls, obtained by mechanical disruption, were purified by enzyme treatment and chemical extractions. [iai.asm.org]
The concentrations of antibodies to these antigens may decrease following treatment, although elevated concentrations may persist in treated patients. [krmc.testcatalog.org]
Prognosis
Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.it]
Prognosis and correlation to lung function. Chest. 1985 Apr. 87(4):460-6. [Medline]. Cormier Y, Brown M, Worthy S, Racine G, Muller NL. High-resolution computed tomographic characteristics in acute farmer's lung and in its follow-up. [emedicine.medscape.com]
Etiology
Changes in pulmonary function were apparent only in the principal ponies, which suggests that neutrophils, per se, do not cause pulmonary dysfunction and that M faeni may be one of the etiologic agents involved in chronic obstructive pulmonary disease [agris.fao.org]
Abstract Published April 1982 Abstract Thermophilic actinomycetes and saprobic fungi are important in the etiology of allergic occupational diseases such as "farmer's lung" disease. Each such organism produces several protein antigens. [clinchem.aaccjnls.org]
Etiology: The disease occurs when sensitized individuals inhale antigens from thermophilic actinomycetes, commonly the spores of Micropolyspora faeni. [msdvetmanual.com]
Bronchiolitis obliterans of unknown etiology Bronchiolitis Obliterans and Organizing Pneumonia Also known as BOOP. Steroids effective. [lumen.luc.edu]
Epidemiology
Abstract To examine factors that influence changes in Micropolyspora faeni (MF) antibody titer in farmer's lung disease (FLD), we followed for 5 yr the prevalence of serum MF antibody and the epidemiologic factors (years on farm, hours in barn, and hay-handling [ncbi.nlm.nih.gov]
His interests are in incontinence in the elderly, the effects of medication and co-morbidity on continence status and the epidemiology and aetiology of incontinence in the elderly. [books.google.ro]
Abstract A total of 888 randomly selected dairy farmers participated in an epidemiological study to evaluate the prevalence of precipitins to farmer's lung antigens, and the socioeconomic factors associated with their presence. [thorax.bmj.com]
Pathophysiology
Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.it]
Useful For Suggests clinical disorders or settings where the test may be helpful Evaluation of patients suspected of having hypersensitivity pneumonitis induced by exposure to Micropolyspora faeni Clinical Information Discusses physiology, pathophysiology [mayomedicallaboratories.com]
Farming is currently ranked as one of the top 3 most hazardous occupations, along with construction and mining. [4, 5] Pathophysiology The pathogenesis of farmer's lung depends on the intensity, frequency, and duration of exposure and on host response [emedicine.medscape.com]
Prevention
Prevention is difficult in areas where hay is likely to be wet during the curing process and it is not possible to alter the feeding regimen. [msdvetmanual.com]