Presentation
Patients were seen for any salivary gland disorder presentation, ranging from sialorrhea to glandular masses. RESULTS: A total of 70.4% of patients presented to the SGDC with a chief complaint of sialorrhea. [ncbi.nlm.nih.gov]
Inflammatory and infectious swellings Inflammatory and infectious swellings present acutely and are often painful enlargements of the salivary glands. [clinicaladvisor.com]
The presentation can be acute, recurrent, or chronic. Acute suppurative sialadenitis presents as rapid-onset pain and swelling and is treated with antibiotics, salivary massage, hydration, and sialagogues such as lemon drops or vitamin C lozenges. [aafp.org]
Tumors of the salivary glands typically present as asymptomatic masses. [asams.org]
[…] in someone who is immunosuppressed or from a high-risk population. [ 6 ] Presentation Swelling which is usually painful and tender. [patient.info]
Entire Body System
- Pain
Once the duct is blocked, typical complaints include foul taste, pain, drainage and swelling. [ctentonline.com]
When saliva can't exit through the ducts, it backs up into the gland, causing pain and swelling. Pain is usually off and on, is felt in one gland, and gets progressively worse. Unless the blockage is cleared, the gland is likely to become infected. [webmd.com]
The symptoms of sialolithiasis include: painful lump under the tongue pain that increases when eating Sialadenitis symptoms include: lump in your cheek or under your chin pus that drains into your mouth strong or foul-smelling pus fever Cysts that grow [healthline.com]
pain Difficulty opening the mouth Prevention of Salivary Gland Disorders There is no known way to prevent salivary gland disorders. [healthcommunities.com]
Sialoliths and granulomatous diseases are inflammatory conditions that cause enlargement and pain but do not have an infectious etiology. [clinicaladvisor.com]
- Inflammation
Sialadenitis (Infection & Inflammation) The most common salivary gland disorder is a painful enlargement of a gland caused by infection and inflammation. This is called sialadenitis. [entassociates.co.nz]
Sialadenitis is inflammation of a salivary gland, usually caused by infections, although there are other less common causes of inflammation such as irradiation, allergic reactions or trauma. [en.wikipedia.org]
salivary fistulas or salivary gland tumours). back up Salivary gland inflammation (sialadenitis) The most frequent salivary gland disorders are acute bacterial and viral inflammations (sialadenitis, sialangitis). [med-college.de]
Chronic nonspecific sialadenitis is a lower grade salivary inflammation that usually involves one or both parotid glands. [clinicaladvisor.com]
Advertisement Salivary glands Inflammation Sialadenitis Topic Completed: 1 September 2015 Revised: 20 March 2019 Copyright: 2002-2019, PathologyOutlines.com, Inc. [pathologyoutlines.com]
- Dentist
To diagnose other causes of swelling, a dentist or doctor may perform a biopsy to obtain a sample of salivary gland tissue and examine it under a microscope. [merckmanuals.com]
It’s not a dentist whom you should consult for your salivary gland problem, but a board-certified ENT (ear/nose/throat), like the specialists at the Salivary Stone Center of Excellence. [salivarystonesmd.com]
Pain or swelling in the face, chin, jawbone area, or neck A difference between the size and/or shape of the left and right sides of the face or neck If you are concerned about any changes you experience, please talk with your doctor and/or dentist right [cancer.net]
Diagnosis of Salivary Gland Disorders Patient history and physical examination, either by a physician or dentist Dental x-rays CT (computed tomography) scans Biopsy of affected salivary glands How to Treat Salivary Gland Disorders Antibiotics are prescribed [healthcommunities.com]
[…] fields: the Depts. of Anatomy, Physiology, Biochemistry, Pharmacology, Pathology, Otolaryngology, Oral and maxillofacial Surgery, Allied Health Science, Domestic Science, Dietetics, Veterinary Medicine, and specialists from universities, medical doctors, dentists [daekisen.org]
- Asymptomatic
Salivary stones are asymptomatic until they become large enough to block the duct. Once the duct is blocked, typical complaints include foul taste, pain, drainage and swelling. [ctentonline.com]
D) Cyst Mucocele RanulaE) Asymptomatic enlargement Sialosis Allergic Associated with malnutrition and alcoholism 7. [slideshare.net]
There is, however, increasing evidence that salivary glands recover function following stone removal and remain asymptomatic. [pocketdentistry.com]
Tumors of the salivary glands typically present as asymptomatic masses. [asams.org]
Neoplasms BENIGN Benign neoplasms of the salivary glands typically present as painless, asymptomatic, slow-growing neck or parotid masses ( Figure 6 ). [aafp.org]
- Malaise
The patient will complain of pain and such symptoms as fever and malaise. Fortunately, the swelling is self-limiting and typically resolves with anti-staphylococcal antibiotic therapy and increased fluid intake. [clinicaladvisor.com]
Children typically present with recurrent episodes of acute or subacute parotid gland swelling with fever, malaise, and pain ( Figure 3 ). The disorder is usually unilateral, but can affect both sides. [aafp.org]
Viral InfectionsMumpsContagious viral infection caused by para myxo virusClinical features Unilateral & bilateral swelling of salivary gland Fever, malaise, anorexia. [slideshare.net]
The patients developed parotid swelling accompanied by fever and general malaise. Cope made wide T-shaped incisions in the gland to allow drainage. Four of the 7 survived after sloughing gangrenous parotid tissue. [emedicine.medscape.com]
Gastrointestinal
- Nausea
Adverse effects of radiation therapy generally include: burning of the skin nausea vomiting fatigue These typically disappear after treatment. Radiation therapy for salivary gland cancer may also travel to other parts of the head and neck. [medicalnewstoday.com]
- Diarrhea
However, some forms of artificial sugar alcohols can cause gas, abdominal pain and diarrhea when eaten in large amounts. [livestrong.com]
Cardiovascular
- Hypertension
Mitsuhiro Kawano and Takako Saeki, IgG4-related kidney disease – an update, Current Opinion in Nephrology and Hypertension, 24, 2, (193), (2015). [doi.org]
Jaw & Teeth
- Xerostomia
Causes severe xerostomia. 12. Diverticuli Small pouches or outpocketing of ductal system of one of the major salivary glands.Congenital fistula Sinus tract form either in crease behind the pinna or in front of tragus. [slideshare.net]
Sjögren’s syndrome consists of a constellation of complaints which include xerostomia, dry eyes (sicca), dry nasal mucosa or vaginal mucosa. [asams.org]
[…] salivary gland K11.6 침샘의 점액유출낭 Mucous extravasation cyst of salivary gland K11.6 침샘의 점액저류낭 Mucous retention cyst of salivary gland K11.6 두꺼비종 Ranula K11.7 침분비의 장애 Disturbances of salivary secretion K11.7 침분비저하 Hypoptyalism K11.7 침과다증 Ptyalism K11.7 구강건조증 Xerostomia [andwin.co.kr]
Salivary gland disorders usually present to clinicians as enlargements (local or generalized), underactivity (xerostomia) or overactivity (ptyalism). Table 25.1 lists pathological entities by clinical classification. [pocketdentistry.com]
If it is a malignant tumor, then radiation therapy will be prescribed which may cause dry mouth syndrome (Xerostomia). For bacterial and viral infections, anti-bacterial and anti-viral medications are required for treatment, respectively. [lybrate.com]
- Bruxism
BtxA 20 units to each smg gland and 30 units to each parotid (100 U) as well 50 units to each masseter for bruxism. [medicine.uiowa.edu]
[…] tooth, unspecified) K02 K02.0 법랑질에 제한된 우식(Caries limited to enamel) 백색반점병변(초기우식)(White spot lesions [initial caries]) K02.1 K02.2 K02.3 K02.4 파치증(Odontoclasia) 영아성 흑색치아(Infantile melanodontia) 흑색파치증(Melanodontoclasia) K02.8 K02.9 K03 - 제외 : 이갈이(F45.8)(Bruxism [koicd.kr]
- Tooth Loss
Aplasia of all salivary glands is rare; resulting xerostomia is associated with increased susceptibility to infection and premature tooth loss. Hypoplasia of a salivary gland, though, is functionally compensated for by the other salivary glands. [med-college.de]
- Aphthous Ulceration
[…] stomatitis (major, minor)) 재발성 점막괴사성 선주위염(periadenitis mucosa necrotica recurrens) 재발성 아프타성 궤양(Recurrent aphthous ulcer) K12.1 K12.2 - 제외 : 편도주위(의) 농양(J36)(Abscess (of) peritonsillar) K12.3 입점막염(궤양성)(Oral mucositis (ulcerative)) 점막염(입의)(입인두의) NOS(Mucositis [koicd.kr]
- Aphthous Stomatitis
stomatitis (major, minor)) 재발성 점막괴사성 선주위염(periadenitis mucosa necrotica recurrens) 재발성 아프타성 궤양(Recurrent aphthous ulcer) K12.1 K12.2 - 제외 : 편도주위(의) 농양(J36)(Abscess (of) peritonsillar) K12.3 입점막염(궤양성)(Oral mucositis (ulcerative)) 점막염(입의)(입인두의) NOS(Mucositis [koicd.kr]
Skin
- Skin Disease
Ohyama, Tidying up the diversity of IgG4‐related skin disease, British Journal of Dermatology, 171, 5, (929-929), (2014). [doi.org]
Psychiatrical
- Fear
They feared the consequences of the unsightly scar and facial paralysis. Parotid abscess is depicted in the image below. Elderly man with parotid abscess. [emedicine.medscape.com]
Neurologic
- Irritability
Problems with salivary glands can cause them to become irritated and swollen. [medlineplus.gov]
Problems with salivary glands can cause the glands to become irritated and swollen. [icd9data.com]
Aplasia of the lacrimal and salivary glands (ALSG) is a rare autosomal dominant disorder characterized by aplasia, atresia or hypoplasia of the lacrimal and salivary glands leading to varying features since infancy such as recurrent eye infections, irritable [orpha.net]
The salivary glands may become inflamed (irritated) because of infection, tumors, or stones. Related topics: Salivary duct stones Salivary duct tumors Salivary gland infections Tests vary depending on the suspected disorder. [lutheranhealthcare.org]
Strictures of the duct system may result from recurrent or chronic irritation of the glands. Certain diseases, such as Sjogren's syndrome, can result in changes in the duct system and the gland itself. [oto.wustl.edu]
- Confusion
In some individuals, the parotid gland symptoms are very similar to and may be confused with Sjögren syndrome. [emedicine.medscape.com]
Workup
Workup should focus on identifying a predisposing factor, such as a calculus or stricture. If no cause is found, treatment is conservative and should consist of sialagogues, massage, hydration, and anti-inflammatory medications. [aafp.org]
Sialography was commonly used in the workup of parotid disease in the past, and this group demonstrates punctate sialectasis, which implies point like dilatations within the gland. Six-year-old girl with recurrent parotitis of childhood. [emedicine.medscape.com]
Treatment
Over 35% of patients had previously attempted medical treatment and 31.5% had no prior treatment attempts. 87% of all patients were offered further treatment options, including interventional, surgical, medical, and conservative measures. [ncbi.nlm.nih.gov]
Surgical Treatment for Disorders of the Salivary Gland Surgical treatment is geared to the specific tumor. Removal of the the parotid or submandibular glands is accomplished in the operating room, under general anesthetic through a neck incision. [entdoctorsphiladelphia.com]
Treatment Like the symptoms, the treatments for salivary gland disorders are also problem specific. For salivary gland tumors, surgery is required. [lybrate.com]
If the mass is cancerous, you may need radiation treatments to kill off cancerous cells. These treatments won’t typically start until your body has had time to heal. This is typically four to six weeks after surgery. [healthline.com]
[v] Lim YC, Choi EC Treatment of an acute salivary fistula after parotid surgery: botulinum toxin type A injection as primary treatment. Eur Arch Otorhinolaryngol. 2008 Feb;265(2):243-5. [medicine.uiowa.edu]
Prognosis
Prognosis for salivary tumors is quite favorable if they are detected early. When to Call a Doctor See your doctor if you develop pain or swelling in or around the mouth or cheek, or if you experience an increase or decrease in saliva production. [healthcommunities.com]
Embryonic rhabdomyosarcomas of the cephalic salivary glands are rare [ 55 ] and have a poor prognosis since the patients present in most cases with already far advanced tumor invasion. [head-face-med.biomedcentral.com]
Outlook Prognosis depends on the stage at which the cancer is diagnosed. Stage 1 salivary gland cancers have a 5-year life expectancy of 91 percent relative to normal for a person's age group. [medicalnewstoday.com]
They tend to grow slowly and have a good outcome (prognosis). Grade 2 cancers (also called intermediate grade or moderately differentiated) have an appearance and outlook that is between grade 1 and grade 3 cancers. [cancer.org]
A malignancy which presents with pain often indicates nerve involvement, and as such, a poorer prognosis. [asams.org]
Etiology
Etiology Infection (Bacterial and Viral) Acute Viral Sialadenitis Over a third of all pediatric salivary gland disorders are of an inflammatory nature, with either an obstructive or non-obstructive etiology. [pocketdentistry.com]
Algorithm for determining the etiology of salivary gland swelling. Information from reference 3. Evaluation of Patients with Suspected Salivary Gland Disorders Figure 1. Algorithm for determining the etiology of salivary gland swelling. [aafp.org]
Sialoliths and granulomatous diseases are inflammatory conditions that cause enlargement and pain but do not have an infectious etiology. [clinicaladvisor.com]
The theories of etiology are diverse. Many authors are convinced that sialoliths or scarring of the ducts cause stasis of salivary flow and predispose the gland to infection is the etiology, but this is probably true for only a minority of cases. [emedicine.medscape.com]
For chronic sialadenitis the predominant etiological factors are secretion disorders and immunological reactions [ 11 ]. [head-face-med.biomedcentral.com]
Epidemiology
Pathology and Genetics of Head and Neck Tumours Lyon, IARC Press, 2005;209-215 Bradley P: General epidemiology and statistics in a defined UK population. [karger.com]
Paediatrics, Neonatology (842) Surgery, Traumatology and Orthopaedics (817) Infectology (706) Biophysics (671) Genetics (659) Neurology (652) Microbiology (501) Dentistry (497) Cardiology, Angiology (479) Pharmacology (392) Emergency Medicine (365) Epidemiology [portal.mefanet.cz]
The epidemiology of the oral lesions of HIV infection in the developed world. Oral Dis 8(Suppl 2): 34 - 39. Google Scholar | Crossref | Medline | ISI Griffiths, DJ, Venables, PJ, Weiss, RA, Boyd, MT ( 1997 ). [doi.org]
NORSK Epidemiology, 18(1): 67 [ PM ] [ EČ ][ GS ] Carbone, A., Gloghini, A., Ferlito, A. (2000) Pathological features of lymphoid proliferations of the salivary glands: lymphoepithelial sialadenitis versus low-grade B-cell lymphoma of the malt type. [scindeks.ceon.rs]
Pathophysiology
Physiology and Pathophysiology (1401) Medical Chemistry and Biochemistry (1273) Internal Medicine (1164) Pathology and Forensic Medicine (978) Anatomy (932) Histology, Embryology (870) Paediatrics, Neonatology (842) Surgery, Traumatology and Orthopaedics [portal.mefanet.cz]
ORL J Otorhinolaryngol Relat Spec. 2012;74(1);12-5 Lakraj AA, Moghimi N and Jabbari B: Sialorrhea: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins. [medicine.uiowa.edu]
Pathophysiology of cystic fibrosis with emphasis on salivary gland involvement. J Dent Res, 66: 667-671, 1987. 14-Hakeem V; Fifield R; al-Bayaty HF; Aldred MJ; Walker DM; Williams J. et al. [scla.org.sy]
Because the pathophysiology is poorly understood, the rationale of several surgical treatments is rather weak. Parotidectomy removes the diseased gland but begs the question of specific treatment. [emedicine.medscape.com]
Kazushige Uchida and Kazuichi Okazaki, Clinical and pathophysiological aspects of type 1 autoimmune pancreatitis, Journal of Gastroenterology, 10.1007/s00535-018-1440-8, 53, 4, (475-483), (2018). [doi.org]
Prevention
Preventative measures FIRST to prevent caries/erosion: -topical fluoride, good dental hygiene Symptomatic measures: -oral rinses and gels, mouthwash, water, decrease caffeine/ETOH Local salivary stimulation- chewing on sugar free gum/candies Systemic [quizlet.com]
Saliva aids in swallowing, prevents infection, and helps keep the mouth and teeth clean. [healthcommunities.com]
Prevention To prevent acute suppurative parotitis, consider risk factors, avoid anticholinergics and other drugs likely to disrupt saliva flow in the vulnerable and maintain good hydration and mouth care perioperatively and amongst critically ill patients [patient.info]
Most of the problems with salivary glands are not preventable. Adequate hydration, use of sialogogues (things that increase salivation -- for example, sour candy), and massage of the gland can increase salivary flow and help prevent infection. [lutheranhealthcare.org]
The best preventative measure is adopting a good oral care routine. [colgate.com]