Presentation
We also present a review of the literature in order to present the most recent and relevant information regarding neurosarcoidosis. [onlinelibrary.wiley.com]
Cryptococcal meningitis in sarcoid patients often presents clinically with non-specific features, and should be excluded in patients with sarcoidosis and neurological disturbances. [tandfonline.com]
The study, “Not everything is as it seems: neurosarcoidosis presenting as leptomeningitis,” was published in the journal Clinical Case Reports. [sarcoidosisnews.com]
Entire Body System
-
Amyloidosis
[…] as lymphoma, meningioma carcinomatous meningitis, and gliomas; infections including neurosyphilis, HIV, tuberculosis, herpes family viruses, toxoplasmosis, and others such as multiple sclerosis, Guillain–Barré syndrome, systemic lupus erythematosus, amyloidosis [onlinelibrary.wiley.com]
-
Galactorrhea
Other manifestations are weight gain, amenorrhea, hypothyroidism, personality changes, temperature dysregulation, galactorrhea, and sleep disorders 2, 4. Involvement of the basal ganglia can cause hemichoreoathetosis 7. [onlinelibrary.wiley.com]
-
Rigor
Malignancy and infection have not been rigorously excluded or there is no pathologic confirmation of systemic sarcoidosis Probable There are clinical and neuroradiologic data suggestive of neurosarcoidosis. [onlinelibrary.wiley.com]
-
Intermittent Fever
Case Report A 39‐year‐old woman without relevant medical history prior to admission presented to the emergency room with a 2‐week gradual onset of frontal headache, intermittent fever, nausea, vomiting, disorientation, and incoherent language. [onlinelibrary.wiley.com]
Psychiatrical
-
Suggestibility
Nonetheless, our patient had white blood cells with polymorphonuclear predominance, pattern suggestive of bacterial meningitis. [onlinelibrary.wiley.com]
Neurologic
-
Meningism
Abstract This report describes a patient with cryptococcal meningitis and newly diagnosed sarcoidosis not taking corticosteroids. [tandfonline.com]
Meningitis is an inflammation of the membranes, called meninges, that surround and protect the brain and spinal cord. [sarcoidosisnews.com]
Clinical course can present as a single episode, recurrent episodes, or as a chronic evolution of aseptic meningitis. Nonetheless, our patient had white blood cells with polymorphonuclear predominance, pattern suggestive of bacterial meningitis. [onlinelibrary.wiley.com]
INFLAMMATORY DPLDs CASE REPORTS Cryptococcal Meningitis: A Complication of Sarcoidosis Abstract Send to Citation Mgr Add to Favorites Email to a Friend Track Citations American Journal of Respiratory and Critical Care Medicine 2020;201:A1532 A. [atsjournals.org]
ALTHOUGH involvement of cranial and peripheral nerves by sarcoidosis is well recognized,1 sarcoidosis affecting the central nervous system and meninges is rare. [jamanetwork.com]
-
Guillain-Barré Syndrome
The most common differential diagnoses are tumors such as lymphoma, meningioma carcinomatous meningitis, and gliomas; infections including neurosyphilis, HIV, tuberculosis, herpes family viruses, toxoplasmosis, and others such as multiple sclerosis, Guillain–Barré [onlinelibrary.wiley.com]
-
Dysarthria
Lower cranial nerves may also be involved, causing dysarthria or dysphagia 2, 4, 9. Sarcoidosis may cause involvement of peripheral nerves in up to 20% of patients. [onlinelibrary.wiley.com]
-
Neurologic Manifestation
About half of patients with neurosarcoidosis can present with neurologic manifestations sooner than systemic sarcoidosis is apparent. [onlinelibrary.wiley.com]
-
Frontal Headache
Case Report A 39‐year‐old woman without relevant medical history prior to admission presented to the emergency room with a 2‐week gradual onset of frontal headache, intermittent fever, nausea, vomiting, disorientation, and incoherent language. [onlinelibrary.wiley.com]
Workup
Due to the multiple clinical manifestations that patients with neurosarcoidosis may have, the diagnostic workup should be complete and multidisciplinary. [onlinelibrary.wiley.com]
Treatment
The treatment will differ depending on the clinical manifestations, but the most common treatment is the use of steroids and other immunosuppressive drugs. [onlinelibrary.wiley.com]
Still, the woman responded well to the treatment, and her symptoms improved. She was discharged three weeks later and told to continue a gradually lessening routine of steroids. A month later, the patient relapsed. [sarcoidosisnews.com]
Etiology
More research needs to be performed to better comprehend the etiology and pathophysiology of sarcoidosis. [onlinelibrary.wiley.com]
Since sarcoidosis is a disease, or a group of diseases, of unknown etiology,2 it is best recognized by its clinicopathological features. [jamanetwork.com]
Pathophysiology
More research needs to be performed to better comprehend the etiology and pathophysiology of sarcoidosis. [onlinelibrary.wiley.com]
Prevention
Radiotherapy is effective in the prevention of progression of local symptoms of neurosarcoidosis and for sarcoid meningitis 2. [onlinelibrary.wiley.com]