We present a case of 35 year-old male who presented with five months history of progressively increasing shortness of breath and cough. On evaluation, there was no air entry on the left side. [ncbi.nlm.nih.gov]

• Swelling

  For example: swelling under the skin may cause a painless lump that cannot easily be moved around and gets bigger over time swelling in the tummy (abdomen) may cause abdominal pain, a persistent feeling of fullness and constipation swelling near the lungs [nhs.uk]

  And because healthy, active children and teens often have pain and swelling in their arms and legs, osteosarcoma might be mistaken for growing pains or a sports injury. [webmd.com]

  When KS affects the lymph nodes and lymph vessels (which form part of the immune system), this can lead to swelling in the arms or legs. This maybe be uncomfortable or painful. [aidsmap.com]

  Pain in the left shoulder continued to worsen and lymph nodes in the supraclavical swelled so I called the onc and they bumped the regular scan up to September 19 and we went for the results on the 24th. [cancerforums.net]

  Lymphoedema is a chronic swelling. This means it never goes way, because the causes cannot be reversed. But some treatments can reduce the swelling. Your doctor can refer you to specialist lymphoedema clinics where you can be treated. [macmillan.org.uk]

• Fever

  Contents SPECIFIC INFECTIOUS DISEASES I Typhoid Fever 1 Typhus Fever 49 Relapsing Fever 53 Copyright 126 other sections not shown Other editions - View all The Principles and Practice of Medicine: Designed for the Use of ..., Volume 82 Sir William Osler [books.google.com.mt]

  Symptoms not commonly associated with pulmonary vascular disease consist of progressive weight loss, anemia, and fever, which are symptoms commonly associated with malignancy. [mayoclinic.pure.elsevier.com]

  Case Report Vishwanath Sathyanarayanan, Nagesh Taterao Sirsath, Umesh Das, M Malathi, Suma Lakshmipathi Reddy, Kavitha S Srivatsa, Avinash Thumallapalli, L Appaji, BS Aruna Kumari We report an unusual case of a 6-year-old male child who presented with fever [ecancer.org]

  Definition / general Rare tumor in lung Associated with chest pain, hemoptysis, dyspnea, cough, fever Rarely is cystic ( Am J Surg Pathol 2010;34:1176 ) 40 - 55% die of disease after 20 years followup, due to metastases to bone, CNS, liver, or invasion [pathologyoutlines.com]

  Symptoms and signs of pulmonary KS include dyspnea (difficulty breathing), fever, non-productive cough, and hemoptysis (coughing up blood). [secure.ssa.gov]

• Weight Loss

  A 41-year-old man with HIV infection, on highly active antiretroviral therapy, presented with haemoptysis, shortness of breath and progressive weight loss for 2 months. [ncbi.nlm.nih.gov]

  Symptoms not commonly associated with pulmonary vascular disease consist of progressive weight loss, anemia, and fever, which are symptoms commonly associated with malignancy. [mayoclinic.pure.elsevier.com]

  Symptoms Cough Bloody sputum Shortness of breath Weight loss Weakness Rib cage pain Note: Sometimes, there are no symptoms. [uclahealth.org]

  Case A 55-year-old female with a history of tobacco use and depression was admitted with progressive dyspnea, cough and 20-pound weight loss for one year that worsened in the last 3 months. [onlinejacc.org]

  Pain around the site of the tumor Swelling and redness around the site of the tumor Fever Weight loss and decreased appetite Fatigue Paralysis and incontinence if the tumor is in the spinal region Symptoms related to nerve compression from a tumor such [ucsfbenioffchildrens.org]

• Fatigue

  Acute toxicities (eg, cough, dyspnea, dysphagia, nausea, and fatigue) were reported in half of the patients treated with whole-lung irradiation. [ascopost.com]

  […] had lower QOL and self-efficacy compared to those with nonsevere fatigue [79]. [hindawi.com]

  It usually presents as a painful mass with fever and fatigue. Plasmacytoma: Arises from plasma cells and is an isolated form of multiple myeloma. You may feel pain but not see a mass. [mountsinai.org]

  Pain around the site of the tumor Swelling and redness around the site of the tumor Fever Weight loss and decreased appetite Fatigue Paralysis and incontinence if the tumor is in the spinal region Symptoms related to nerve compression from a tumor such [ucsfbenioffchildrens.org]

  My hair all turned snow white, I have significant fatigue, loss of appetite, and a lot of diareha. I have lost almost 30 pounds this year - and not by trying! Lol. However - I do have good days, and I would say above average quality of life still. [cancercompass.com]

• Anemia

  Symptoms not commonly associated with pulmonary vascular disease consist of progressive weight loss, anemia, and fever, which are symptoms commonly associated with malignancy. [mayoclinic.pure.elsevier.com]

  Full view - 1876 The American Journal of the Medical Sciences, Volume 54 Full view - 1867 The American Journal of the Medical Sciences, Volumes 63-64 Full view - 1872 View all » Common terms and phrases abdomen achylia acid acute aged albumin amount anemia [books.google.com.mt]

  Over a long term bleeding may lead to anemia. This is caused due to lowering in the number of red blood cells. [news-medical.net]

  Complete blood count was significant for normocytic anemia and metabolic panel was within normal limits. Absolute CD4 cell count is of 102 cells μ/L (17%). [hindawi.com]

• Aspiration

  The fine needle aspiration cytology (FNAC) of this lesion was suggestive of pulmonary granulocytic sarcoma. [ecancer.org]

  Fine-needle aspiration (FNA) cytology of soft-tissue tumors is evolving. As more experience is gained, we are becoming aware of potential pitfalls. [ncbi.nlm.nih.gov]

  To the Editors: We read with interest the correspondence published by Park et al. [1] suggesting a potential role for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) to differentiate pulmonary artery sarcoma and thromboembolism [erj.ersjournals.com]

  A pathologist will then examine these samples under a microscope after processing the tissue in a laboratory Fine needle aspiration biopsy (FNAB): During fine needle aspiration biopsy, a device called a cannula is used to extract tissue or fluid from [dovemed.com]

  CT guided fine needle aspiration cytology (FNAC) done from right lung SOL revealed spindle cell neoplasm [Figure 2]. Pleural fluid analysis was negative for malignant cells. Further work up for metastasis was negative. [lungindia.com]

• Hemoptysis

  Definition / general Rare tumor in lung Associated with chest pain, hemoptysis, dyspnea, cough, fever Rarely is cystic ( Am J Surg Pathol 2010;34:1176 ) 40 - 55% die of disease after 20 years followup, due to metastases to bone, CNS, liver, or invasion [pathologyoutlines.com]

  Symptoms and signs of pulmonary KS include dyspnea (difficulty breathing), fever, non-productive cough, and hemoptysis (coughing up blood). [secure.ssa.gov]

  Case Report A 26-year-old African American man with AIDS presented with complaints of pleuritic chest pain, exertional shortness of breath, and hemoptysis of 3-week duration. [hindawi.com]

  Keywords: Pulmonary synovial sarcoma; Hemoptysis; Thoracotomy; Radiotherapy CASE REPORT A 32-year-old female presented with complaints of cough, chest pain and dyspnea for the past one and a half month and hemoptysis for one week. [jpmsonline.com]

  Measurements and results: Presenting symptoms of patients with pulmonary artery sarcoma are similar to those of patients with other pulmonary vascular disease, including progressive dyspnea, cough, hemoptysis, and chest pain. [mayoclinic.pure.elsevier.com]

• Fracture

  […] carcinoma cause cells cent changes chest chronic clinical complete condition considered definite demonstrated determine developed diagnosis diaphragm disease dose early effect entire evidence examination experience extensive fact filter findings four fracture [books.google.com.mt]

  Driver and Novel Coronavirus 1067-1068 Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis 1068-1070 A Locally Transmitted Case of SARS-CoV-2 Infection in Taiwan 1070-1072 Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture [nejm.org]

  Other presentations depend on the specific anatomical location(s), i.e. pneumothorax (punctured lung) or hemoptysis (coughing blood) or cough due to lung metastasis, bone pain or pathological fracture due to bone metastasis, G.I. symptoms due to metastasis [curesarcoma.org]

  Pneumonitis 6 Cough 2 Esophageal stricture 1 Pain 1 Dermatitis 1 Rib fracture 1 Dyspnea 1 4. [hindawi.com]

  […] possible increased risk of developing other cancers; fertility problems Amputation-related problems can include: an adjustment period while the child learns to learn to use a prosthetic long-term psychological and social issues related to the prosthesis fracture [kidshealth.org]

• Back Pain

  I dont have any back pain or pain what so ever. Did how ever have Pulmonary obstructive Phenomena for about a year. seemed to clear up on its own. Not sure if the vitaminn D3 had something to do with it. [cancercompass.com]

  Aquilina 64 2 2/0 38.5 C2-4, D10 Surgery Radiation CHT (ifosfamide+carboplatin+etoposide+vincristine) None Not stated Nocturnal thoracic low-back pain Neck pain Pinet 65 1 0/1 50 Parietal pleura CHT (carboplatin +etoposide) Peritoneum Not stated (complete [ncbi.nlm.nih.gov]

  […] bone Decreased motor skills; including difficulty walking or limping Weak bones, which may lead to a fracture Fatigue Weight loss Fever Anemia A Ewing sarcoma located near the spinal cord may cause back pain that radiates out through the arms or legs. [chop.edu]

  Cough, shortness of breath, back pain - all come and go. [cancerforums.net]

  Disseminated AIDS-related KS in a 41-year-old man with chronic back pain. (a) Abdominal CT scan demonstrates an ill-defined, hypoattenuating osseous lesion (arrow) in the posterior aspect of the right iliac bone. [pubs.rsna.org]

• Aggressive Behavior

  Because of its potential for aggressive behavior, clinicians must be aware of the presenting behavior of ES in order to avoid misdiagnosis. [ncbi.nlm.nih.gov]

  Begueret et al4 reported that almost 40% of primary pulmonary and mediastinal synovial sarcomas were poorly differentiated, a finding consistent with the tumors' aggressive behavior.4 With rare exceptions, primary pulmonary and mediastinal synovial sarcomas [nature.com]

  Poorly Differentiated Synovial Sarcoma is considered as a form of progression, with a more aggressive behavior and a higher percentage of metastase. 1 In the less cellular areas there can be hyalinization, myxoid changes and calcifications, with or without [sarcomahelp.org]

• Asthenia

  The patients may present with dyspnea, pleuritic pain, cough and hemoptysis, which can be interpreted as pulmonary thromboembolism or signs and symptoms of neoplasm1 (asthenia, weight loss, and poor general condition). [revespcardiol.org]

• Irritability

  /3 Sickling sensations of the left arm 1/3 Radzikowska 18 1 0/1 62 Multiple bilateral Interferon-2 None 6 months (then lost at observation) Cough Osteo-articular pain Ye 19 1 0/1 55 Multiple bilateral None (refused) Liver 7 months Pleuritic pain and irritable [ncbi.nlm.nih.gov]

Following a broad workup, HHV-8 PCR and a lymph node biopsy confirmed pulmonary Kaposi-sarcoma. Workup for multicentric Castleman disease was negative. The patient was treated with liposomal doxorubicin, ganciclovir, and prednisone. [cureus.com]

For certain tumor types, further workup may include a CT scan to search for disease that has spread. [floridaproton.org]

In this series, four patients with pericardial effusions were at first thought to have nonneoplastic disease, the workups of whom included two negative bloody pericardial fluid cytology exams, and two patients were initially treated with prednisone for [nature.com]

[…] an underlying lung cancer at younger ages.[5] Importantly, many of these signs are commonly due to other causes which are not cancer.[6] A detailed medical history should be obtained from each patient to determine the relevance of further diagnostic workup [en.wikipedia.org]

• Pulmonary Infiltrate

  Kaposi’s sarcoma causing pulmonary infiltrates and respiratory failure in the acquired immunodeficiency syndrome. Ann Intern Med1985;102:471–475. Crossref, Medline, Google Scholar 45 MeduriGU, Stover DE, Lee M, Myskowski PL, Caravelli JF, Zaman MB. [pubs.rsna.org]

• Human Herpesvirus 8

  KS is caused by infection with human herpesvirus-8 (HHV-8). Most people infected with HHV-8 don't get KS. [medlineplus.gov]

  Definition / general Vascular neoplasm caused by human herpesvirus 8 (HHV8) Tends to be indolent but may be locally aggressive Essential features Etiologic agent of all forms and cases is human herpesvirus 8 (HHV8), HHV8 immunostain will distinguish it [pathologyoutlines.com]

  Kaposi Sarcoma (KS) is the most common malignancy associated with Acquired Immune Deficiency Syndrome (AIDS) and is caused by Human Herpesvirus 8 (HHV 8) or Kaposi Sarcoma Herpesvirus (KSHV). [hindawi.com]

  herpesvirus 8 is the suspected cause. [icd10data.com]

  The underlying cause of Kaposi's sarcoma is infection with a virus called human herpesvirus 8 (HHV-8). In healthy people, HHV-8 infection usually causes no symptoms because the immune system keeps it under control. [mayoclinic.org]

Due to the rarity of this disease, no guidelines for the treatment are available. Main existing treatment includes surgery followed by either radiation, chemotherapy or both. [ncbi.nlm.nih.gov]

All SBRT/IGRT technologies utilized for treatment delivery were performed on Elekta Synergy or infinity radiotherapy treatment delivery systems. [hindawi.com]

(d), and time between the initial diagnosis and start of treatment (e). [onlinelibrary.wiley.com]

Treatment with pazopanib 800 mg was started. After 2.5 months of treatment, a clear reduction in the size of the pulmonary metastases was shown. [karger.com]

[…] health have better prognosis compared with those with poor health Age of the individual: Older individuals generally have poorer prognosis than younger individuals Individuals with bulky disease of the lung cancer have a poorer prognosis Involvement [dovemed.com]

If you have soft tissue sarcoma, you may have questions about your prognosis. A prognosis is the doctor’s best estimate of how cancer will affect someone and how it will respond to treatment. Prognosis and survival depend on many factors. [cancer.ca]

Details of the histological findings are presented, and the factors associated with good prognosis discussed. Immunocytochemical stains were carried out this year when the case was reviewed, and not at the time of resection. [ncbi.nlm.nih.gov]

ICD-10-CM Codes › C00-D49 Neoplasms › C45-C49 Malignant neoplasms of mesothelial and soft tissue › Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Originally, the disease was believed to be a form of primary skin cancer; however, a viral etiology now has been firmly established. [1, 2, 3, 4] Bronchopulmonary KS has been found on autopsy in 47% of patients with AIDS who had cutaneous Ks. [5] Preferred [emedicine.medscape.com]

Conclusion In the right clinical setting, pulmonary artery sarcoma can be the etiology of dyspnea. As pulmonary embolism is diagnosed in a critically ill patient with dyspnea, other causes for pulmonary artery obstruction should also be considered. [onlinejacc.org]

During this encounter, however, the inpatient lymph node biopsy was indicated due to generalized lymphadenopathy of unclear etiology and worsening clinical status [8]. [cureus.com]

Definition / general Vascular neoplasm caused by human herpesvirus 8 (HHV8) Tends to be indolent but may be locally aggressive Essential features Etiologic agent of all forms and cases is human herpesvirus 8 (HHV8), HHV8 immunostain will distinguish it [pathologyoutlines.com]

A population-based epidemiologic and prognostic study of 137 patients. Cancer 1991; 67: 499-505. Mentzel T, Beham A, Katenkamp D, Dei Tos AP, Fletcher CD. [medigraphic.com]

[…] other markers FISH positive for EWSR1 rearrangement (85%) Terminology Low grade malignant myxoid endobronchial tumor ICD coding ICD-O: 8842 / 3 - primary pulmonary myxoid sarcoma ICD-10: C34.9 - malignant primary bronchiogenic / bronchogenic neoplasm Epidemiology [pathologyoutlines.com]

Epidemiology Synovial sarcoma is the fourth most commonly occurring sarcoma, accounting for 8-10 % of all sarcoma. The incidence is estimated to be 900 new cases a year in US. [curesarcoma.org]

Update on KSHV-Epidemiology, Kaposi Sarcoma Pathogenesis, and Treatment of Kaposi Sarcoma. Cancer letters. 2011; 305(2): 150–162. doi:10.1016/j.canlet.2011.02.006. PubMed. [dermnetnz.org]

Pathophysiology[edit] The respiratory tract can be divided into two main components: the conducting airways and the gas exchange airways. [en.wikipedia.org]

Awareness of this potential pitfall may aid in preventing a misdiagnosis. Its recognition is of major concern, especially for the poorly differentiated variant, because it is associated with a worse prognosis. [ncbi.nlm.nih.gov]

Prevention Not all cancers can be prevented, but many can be by not smoking, eating a healthy diet, exercising regularly, and keeping alcohol consumption moderate. [uclahealth.org]

How can I prevent Kaposi’s sarcoma? Kaposi sarcoma is caused by the HHV-8 infection. There are no vaccines to protect against it at this point. Preventing the transmission of HHV-8 is the best way to prevent KS. [oncolink.org]

Available online at www.cancer.org/cancer/lung-cancer/prevention-and-early-detection.html. Accessed Sept 15, 2018. (16 May 2016, Revised) About Non-Small Cell Lung Cancer. American Cancer Society. [labtestsonline.it]