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Sarcoma of the Lung

Sarcoma of Lung


  • We present a case of 35 year-old male who presented with five months history of progressively increasing shortness of breath and cough. On evaluation, there was no air entry on the left side.[ncbi.nlm.nih.gov]
  • They usually present as an abdominal or pelvic mass lesion. CASE PRESENTATION: In 2007, a 45-year-old woman underwent total hysterectomy for in situ squamous cell carcinoma of the cervix.[ncbi.nlm.nih.gov]
  • We present the first reported case of primary pulmonary synovial sarcoma with intra cardiac extension in a 53-year-old male who presented with chronic cough.[ncbi.nlm.nih.gov]
  • A case is presented of a successfully resected primary pulmonary sarcoma in a 27-year-old man, followed by an eight-year disease-free follow-up.[ncbi.nlm.nih.gov]
  • A series of nine patients is presented, all of whom were seen in Edinburgh. In each case there is histological proof of the diagnosis or sarcoma.[ncbi.nlm.nih.gov]
  • A balanced translocation between chromosomes X and 18, demonstrated by both karyotyping and fluorescent in situ hybridization (FISH), enabled us to make a diagnosis of synovial sarcoma, which was histologically classified as poorly differentiated.[ncbi.nlm.nih.gov]
  • The use of molecular techniques like immunohistochemistry (IHC), polymerase chain reaction (PCR) and fluorescence in situ hybridization (FISH) is required for confirmation of diagnosis.[f1000research.com]
  • After I had cancer, I confined myself to eating steam vegetables and fruit juices and it was only later that I ventured into taking steam fish. I found it hard initially because there was no sugar, salts, etc.[ispub.com]
Axillary Mass
  • A 46-year-old man was admitted to hospital due to progressive dyspnoea and a painless axillary mass that he had had for several months ( Fig. 1 ).[archbronconeumol.org]
Mediastinal Lymphadenopathy
  • Small volume mediastinal lymphadenopathy. Biopsy Report A mass formed of spindle shaped cells surrounding cleft like spaces situated in the lung. Hyperchromatic and pleomorphic nuclei. Stains for pneumocystis carinii are negative.[radiopaedia.org]
Pelvic Mass
  • They usually present as an abdominal or pelvic mass lesion. CASE PRESENTATION: In 2007, a 45-year-old woman underwent total hysterectomy for in situ squamous cell carcinoma of the cervix.[ncbi.nlm.nih.gov]
  • Examination of the abdomen did not reveal any lymphadenopathy, ascites and hepatosplenomegaly. Other systems were within normal limits. Complete hemogram and blood biochemistries were within the normal limit.[ccij-online.org]
  • Small purple papules on limbs. Patient Data Age: 40 years Gender: Male Loading images... Multifocal consolidation both lungs with a 'flame shaped' appearance, best observed in the upper lobes.[radiopaedia.org]


  • For certain tumor types, further workup may include a CT scan to search for disease that has spread.[floridaproton.org]
  • In this series, four patients with pericardial effusions were at first thought to have nonneoplastic disease, the workups of whom included two negative bloody pericardial fluid cytology exams, and two patients were initially treated with prednisone for[nature.com]


  • Due to the rarity of this disease, no guidelines for the treatment are available. Main existing treatment includes surgery followed by either radiation, chemotherapy or both.[ncbi.nlm.nih.gov]
  • Moreover, extensive literature review is reported, along with differential diagnoses, immunohistochemical and molecular findings, pathogenetic hypotheses and treatment options.[ncbi.nlm.nih.gov]
  • A seven-year old boy admitted to the hospital for treatment of leukemia having radiological findings of consolidation in one lung.[ncbi.nlm.nih.gov]
  • Treatment with pazopanib 800 mg was started. After 2.5 months of treatment, a clear reduction in the size of the pulmonary metastases was shown.[karger.com]
  • Radical resection is the only curative treatment in patients with primary pulmonary sarcoma. All 4 patients (18%) who did not undergo operation died within 17 months.[ncbi.nlm.nih.gov]


  • Details of the histological findings are presented, and the factors associated with good prognosis discussed. Immunocytochemical stains were carried out this year when the case was reviewed, and not at the time of resection.[ncbi.nlm.nih.gov]
  • The five-year survival rate after 'curative' surgery is 52%, and the prognosis after surgery does not appear to depend on the radical nature of the operation.[ncbi.nlm.nih.gov]
  • Its recognition is of major concern, especially for the poorly differentiated variant, because it is associated with a worse prognosis.[ncbi.nlm.nih.gov]
  • It has high rates of local recurrence and distant metastasis, and the prognosis after metastasis is poor.[karger.com]
  • Primary sarcoma of the lung: A very rare diagnosis and poor prognosis.[ccij-online.org]


  • ICD-10-CM Codes › C00-D49 Neoplasms › C45-C49 Malignant neoplasms of mesothelial and soft tissue › Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10data.com]
  • Definition / general Vascular neoplasm caused by human herpesvirus 8 (HHV8) Tends to be indolent but may be locally aggressive Essential features Etiologic agent of all forms and cases is human herpesvirus 8 (HHV8), HHV8 immunostain will distinguish it[pathologyoutlines.com]
  • This also leads to a broad clinical etiologic differential. Open-lung biopsy is often required to make what is commonly an unsuspected diagnosis. References 1 Meis-Kindblom JM, Kindblom L-G. Angiosarcoma of soft tissue: a study of 80 cases.[nature.com]
  • The etiology is still a dilemma. Studies about suggestive hypothesis are ongoing.[ncbi.nlm.nih.gov]


  • A population-based epidemiologic and prognostic study of 137 patients. Cancer 1991; 67: 499-505. Mentzel T, Beham A, Katenkamp D, Dei Tos AP, Fletcher CD.[medigraphic.com]
  • Epidemiology Synovial sarcoma is the fourth most commonly occurring sarcoma, accounting for 8-10 % of all sarcoma. The incidence is estimated to be 900 new cases a year in US.[curesarcoma.org]
  • […] cells with minimal to moderate atypia; hemorrhage, hemosiderin and plasma cells are key histologic clues Can histologically mimic angiosarcoma; distinction is critical, as behavior and treatment are very different ICD coding ICD-10: C46 - Kaposi sarcoma Epidemiology[pathologyoutlines.com]
Sex distribution
Age distribution


  • Awareness of this potential pitfall may aid in preventing a misdiagnosis. Its recognition is of major concern, especially for the poorly differentiated variant, because it is associated with a worse prognosis.[ncbi.nlm.nih.gov]
  • Prevention Not all cancers can be prevented, but many can be by not smoking, eating a healthy diet, exercising regularly, and keeping alcohol consumption moderate.[uclahealth.org]
  • These treatments can also be given prior to surgery to shrink tumors and prevent the spread of cancer cells through the blood stream. This is called neoadjuvant therapy.[hopkinsmedicine.org]
  • Chemotherapy is an art and science and the right combinations of treatments aggressively eliminates cancer, prevents recurrence and maintains the patient’s quality of life through treatment. Over 50% of Dr.[sarcomaoncology.com]
  • Radiation is occasionally used to try and prevent tumor recurrence, and chemotherapy is largely ineffective for this diagnosis. These tumors metastasize (spread) very, very rarely.[sarctrials.org]

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