technician, University of Foggia; FP, VC and MG (MD): Staff physician, Pediatric Nephrology Unit, Ospedale “Giovanni XXIII”, Bari; GG: Associate Professor of Nephrology, University of Foggia; LG: Full Professor of Nephrology, University of Bari. [bmcnephrol.biomedcentral.com]

Some affected individuals also have heat intolerance and develop CNS symptoms during hot weather [ Baradaran-Heravi et al 2012a ]. [ncbi.nlm.nih.gov]

Her infections have included otitis media, sinusitis, pharyngitis, bacterial pneumonia, respiratory syncytial virus pneumonia, Pneumocysitis carinii pneumonia, mycoplasma pneumonia, gastroenteritis, herpes zoster, and fungal skin infections as well as [jmg.bmj.com]

Goldman perimetry was abnormal in both patients with classic ring scotomas in three of the eyes and no peripheral sparing in the left eye of the younger sibling. ERG of the older sibling revealed decreased cone and rod responses in both eyes. [iovs.arvojournals.org]

At 8 years of age, she developed symptoms of central nervous system (CNS) vascular impairment including recurrent headaches with nausea, vomiting, blurred vision, hallucinations, and dysosmia. [jmg.bmj.com]

To our knowledge this is the first reported patient with SID, profound mental retardation, and a seizure disorder. [ncbi.nlm.nih.gov]

At 8 years of age, she developed symptoms of central nervous system (CNS) vascular impairment including recurrent headaches with nausea, vomiting, blurred vision, hallucinations, and dysosmia. [jmg.bmj.com]

Neurologic manifestations Individuals with transient ischemic attacks or strokes usually show temporary improvement on treatment with agents that improve blood flow or decrease coagulability (pentoxifylline, acetylsalicylic acid, dipyridamole, warfarin [ncbi.nlm.nih.gov]

Life expectancy is limited to childhood or early adolescence in most patients, due to stroke, severe opportunistic infections, bone marrow failure, complications of kidney failure, congestive heart failure, and unspecified lung disease. [cags.org.ae]

Complications of the severe form of SIOD can include strokes, severe opportunistic infections, bone marrow failure, and kidney failure that can be life-threatening early in life. [diseaseinfosearch.org]

Key words Osteochondrodysplasia Cerebral ischaemia Immunologic deficiency syndrome Kidney failure Hypothyroidism Focal glomerulosclerosis This is a preview of subscription content, log in to check access. Preview Unable to display preview. [link.springer.com]

Causes of death may include stroke, severe opportunistic infection, bone marrow failure, complications of kidney failure, congestive heart failure, or lung disease. Those with milder symptoms survive into adulthood if kidney disease is well-managed. [rarediseases.info.nih.gov]

We do know he will have kidney failure in 5 to 10 years though and we have to be very aggressive treating his symptoms of any sickness as they come. [littlegiantsfoundation.blogspot.com]

Of 512 consecutive prospective donors, 14 (2.7%) continued to have asymptomatic, microscopic hematuria over 1 month. [scinapse.io]

Microscopic hematuria was present in only one patient at disease onset. Focal segmental glomerulosclerosis (FSGS) was found in 82% of biopsies, including three differentiated as collapsing and one as hilar lesion subtypes. [journals.plos.org]

Therefore, vaccination with all live vaccines should be avoided, including rotavirus, MMR, varicella, BCG, oral Salmonella typhi vaccine, and yellow fever virus vaccine. Anti-cancer therapies. [ncbi.nlm.nih.gov]

MRI studies of the CNS revealed progressive white matter lesions. Morphological changes as well as neurological deficits are compatible with cerebral ischaemia. [springerlink.com]