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Schistosoma


Presentation

  • It could present with common as well as unusual urological symptoms, which poses a considerable diagnostic challenge in countries where there is relative low incidence of the disease.[ncbi.nlm.nih.gov]
Camping
  • It also highlights the possible crosstalk between the parasite's intracellular cyclic adenosine monophosphate (cAMP) and p38 mitogen-activated protein kinase (p38 MAPK) during the intramolluscan stage.[ncbi.nlm.nih.gov]
Pseudotumor
  • An uncommon case of ovarian pseudotumor due to Manson's schistosomiasis is reported.[ncbi.nlm.nih.gov]
School Problem
  • problems (academic difficulties, included attention problems and learning problems), and the composite behavioral symptoms index (BSI), signifying improved behavior.[ncbi.nlm.nih.gov]
Proximal Muscle Weakness
  • We present a novel serological method, using paired liquor and serum samples, resulting in the diagnosis of Schistosoma myelopathy in a male patient with proximal muscle weakness. The patient recovered after praziquantel treatment.[ncbi.nlm.nih.gov]
Neck Stiffness
  • Abstract A six year old girl was admitted to the Kenyatta National Hospital paediatric unit with history of headaches, fever, neck stiffness and paraesthesias of the lower limbs. She was empirically commenced on antimeningitic treatment.[ncbi.nlm.nih.gov]
Hyperactivity
  • BASC-2 T scores were significantly reduced post-treatment (p 0.05) for each of the 'negative' behavior categories including externalizing problems (hyperactivity, aggression, and conduct problems that are disruptive in nature), internalizing problems[ncbi.nlm.nih.gov]

Workup

  • Subsequently, the patient was referred to our institution for further workup. Upon presentation to our institute, the patient's temperature was 36.8 C, his pulse was 60 beats per minute (bpm), and his blood pressure was 120/70 mm Hg.[jcm.asm.org]
Hypercholesterolemia
  • METHOD: It was reported a case of a 36 years old patient, brown, with classical sintoms of nephrotic syndrome (proteinuria 3.5 g/24h, hypoalbuminemia and hypercholesterolemia), however with hepatosplenic schistosomiasis history 7 years ago and portal[ncbi.nlm.nih.gov]
Brugia Malayi
  • The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products. Mol. Biochem. Parasitol. 160, 8–21 (2008). 48. Bennuru, S. et al.[doi.org]
Granulomatous Tissue
  • Histology revealed a schistosoma mansoni ovum surrounded by granulomatous tissue with giant cells and polymorphoneuclear leucocytes. The child was commenced on paziquantel 1000 mg and dexamethasone 24 mg per day in divided doses.[ncbi.nlm.nih.gov]

Treatment

  • Here CCA levels are measured 24 hours post treatment in response to both a single and two treatments.[ncbi.nlm.nih.gov]

Prognosis

  • The prognosis of schistosomiasisassociated PAH is not well understood and is likely very similar to that of idiopathic PAH.[phassociation.org]
  • What is the prognosis (outcome) for schistosomiasis? Early antiparasitic treatment, especially with acute schistosomiasis, may allow people to recover completely without developing chronic disease.[medicinenet.com]
  • The prognosis is excellent, and a single dose of praziquantel 40mg/kg cures 80% of infected persons. Follow-up urine or stool specimens should be collected at 6 to 8 weeks and 6 months to ensure clearance of the eggs.[coursera.org]
  • If someone is also infected with malaria, HIV, or hepatitis, there is a worse prognosis. Can schistosomiasis be prevented? People who travel to areas affected by schistosomiasis should avoid exposure to fresh water that is likely to be contaminated.[patient.info]
  • As the prognosis in SMR depends in part on factors related to the disease itself and in part on early treatment (Ferrari 1999), it has been recommended the empirical use of PZQ in combination with a corticosteroid in suspected cases while the diagnosis[scielo.br]

Etiology

  • Etiology Clinical features Clinical features depend on the stage, schistosome type, and infected organs.[amboss.com]
  • Etiology: The trematodes (flukes) . Schistosomes are flukes that inhabit the portal vascular system. All species have similar life cycles.[meddean.luc.edu]
  • Schistosomiasis by Paul Stewart Disease Etiology Schistosomiasis, also known as bilharziasis or snail fever, is caused by infection of digenetic blood trematodes (i.e., helminth parasites such as flukeworms) .[austincc.edu]
  • However, the patients who underwent surgical treatment did not have a previous etiologic diagnosis. 6 - 10 The “gold standard” treatment for cerebral S mansoni schistosomiasis remains to be determined.[jamanetwork.com]
  • Key words: schistosomiasis - neuroschistosomiasis - central nervous system/parasitology - Schistosoma mansoni - Schistosama japonicum -Schistosoma haematobium ETIOLOGY AND EPIDEMIOLOGY The term neuroschistosomiasis (NS) refers to the symptomatic or asymptomatic[scielo.br]

Epidemiology

  • A classification and regression tree modeling (CART) was then used to explore the relationship between socioeconomic, demographic, and epidemiological variables and their reinfection status.[ncbi.nlm.nih.gov]
  • Links Rodents as natural hosts of zoonotic Schistosoma species and hybrids: an epidemiological and evolutionary perspective from West Africa[gov.uk]
Sex distribution
Age distribution

Pathophysiology

  • Useful For Suggests clinical disorders or settings where the test may be helpful As an aid in diagnosing schistosomiasis infections involving the urinary tract Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as[mayomedicallaboratories.com]
  • Now we're going to talk about schistosomiasis: pathophysiology, clinical manifestations and treatment. It's important to think about the timeline of schistosomiasis.[coursera.org]
  • -N.Z. and J.U.); Mechanisms/pathophysiology (B.J.V., D.W.D. and M.S.); Diagnosis, screening and prevention (B.J.V., M.S., D.W.D. and D.P.M.); Management (D.P.M.); Quality of life (J.U.); Outlook (D.P.M. and B.J.V.); Overview of Primer (D.P.M.).[nature.com]
  • The pathophysiology of PH associated with schistosomiasis is matter of debate.[ahajournals.org]

Prevention

  • A guide to ranking the risk factors for Schistosoma mansoni reinfection would greatly contribute to prioritizing resources and focusing prevention and control measures to prevent rapid reinfection.[ncbi.nlm.nih.gov]
  • Combination treatment may prevent morbidity due to schistosomiasis. Praziquantel is most active against adult worms. However, it has been found that artemether prevents the development of adult worms, thus decreasing egg production in the host.[en.wikipedia.org]

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