In a patient presenting with hematuria and proteinuria (albuminuria), bladder biopsy demonstrated Schistosoma hematobium infection and renal biopsy showed a minimal change glomerulonephritis. [ncbi.nlm.nih.gov]

In the present study, a 25% reinfection rate at 9 months post-treatment was observed. [parasitesandvectors.biomedcentral.com]

Presented in part: 11th International Congress of Parasitological Associations, Glasgow, Scotland, 6–11 August 2006. [academic.oup.com]

Twenty percent of the dysplastic bladders presented a mutation in Kras gene. [flipper.diff.org]

With urogenital schistosomiasis, the most common presentations are dysuria, frequency and haematuria [ 10 ]. [omicsonline.org]

• Chronic Infection

  Abstract Definitive diagnosis of Schistosoma haematobium infection in adult patients is a clinically important challenge. Chronically infected adults pass few eggs in the urine, which are often missed when current diagnostic methods are used. [ncbi.nlm.nih.gov]

  In chronic infections, or if eggs are difficult to find, an intradermal infection of schistosome antigen to form a heal is effective in determining infection. Alternate diagnosis can be made by complement fixation tests. [kullabs.com]

  Chronic schistosomiasis can develop months or even years after the initial infection and cause long-term health problems. Damage to the organs after chronic infection is irreversible. [yourgenome.org]

  In chronic infections, damage to the urinary system can occur, such as fibrosis of the bladder and ureter, as well as kidney damage that may lead to kidney failure. [news-medical.net]

  Chronic infection can cause substantial morbidity and long-term complications as the eggs become trapped in human tissues causing inflammation and fibrosis. We summarised evidence of drugs active against the infection. [cochrane.org]

• Hepatomegaly

  Physical examination is notable for hepatomegaly, most prominent in the left hepatic lobe. She also has an urticarial rash in her left foot. [medbullets.com]

  In acute infections with heavy infection due to Schistosoma mansoni or Schistosoma japonicum, a mucoid bloody diarrhea accompanied by tender hepatomegaly occurs. [meddean.luc.edu]

  Ultrasound examination showed hepatomegaly and portal fibrosis. Microscopic examination revealed round or oval eggs embedded in the parenchyma of liver along with periportal fibrosis. [community.vanguardngr.com]

  Complications (for example, hepatomegaly or enlarged liver and bladder cancer) related to the disease are thought to occur due to long-term exposure to the highly antigenic eggs. [medicinenet.com]

  In addition, hepatomegaly is a common symptom in the early stages of the disease and is often accompanied by a fluid accumulation in the peritoneal cavity and an increase of pressure in the intestinal vessels. [dovepress.com]

• Ulcer

  Controls (n = 429) were recruited at random from residents of eight current Buruli ulcer foci in the Couffo Department. Past or current Buruli ulcer patients were excluded from the lottery for controls. [ncbi.nlm.nih.gov]

  Definition / general Deposition of Schistosoma eggs in bladder causes eosinophilic inflammation, necrosis and ulceration, followed by fibrosis with chronic inflammatory infiltrate Epidemiology Schistosoma haematobium infection is common in Africa and [pathologyoutlines.com]

  Pathology The ova are initially deposited in the muscular Propecia which leads to ulceration of the overlying tissue. Infection is characterized by pronounced acute inflammation, squamous metaplasia, blood and reactive epithelial changes. [kullabs.com]

  Bowel S. mansoni and japonicum produce congestion and ulceration of the bowel wall. Long-term involvement of the colon produces abdominal pain and bloody diarrhea. [meddean.luc.edu]

  Granulomata in turn coalesce to form tubercles, nodules or masses that often ulcerate. [en.wikipedia.org]

• Hematuria

  The hematuria and proteinuria resolved following praziquantel therapy. The pathogenesis of glomerulonephritis in association with Schistosoma infection is discussed. [ncbi.nlm.nih.gov]

  The total absence of hematuria, proteinuria and leukocyturia, however, may be used to rule out heavy infections in community surveys. [brightresearch.org]

  Of the 542 schistosome infected individuals, 73 showed hematuria. [pubs.sciepub.com]

• Dysuria

  […] after their death, large numbers of calcified eggs can be found in bladder wall Diagrams / tables Images hosted on other servers: Life cycle Clinical features May clinically simulate urothelial carcinoma Symptoms are nonspecific; common symptoms are dysuria [pathologyoutlines.com]

  Urinary symptoms may include frequent urination, painful urination (dysuria), and blood in the urine (hematuria). 13. [fr.slideshare.net]

  With urogenital schistosomiasis, the most common presentations are dysuria, frequency and haematuria [ 10 ]. [omicsonline.org]

  The common presenting symptoms of carcinoma ol the bladder were haematuria, pyuria, hypogastric pain, dysuria and frequency. More than a third of the patients had palpable suprapubic masses on admission. The tumours were often large and sessile. [erepository.uonbi.ac.ke]

  Symptoms and signs include dysuria, urgency, terminal microscopic and gross hematuria, secondary urinary tract infections, and nonspecific pelvic pain. Chronic urinary carriage and bacteremia with salmonella can occur. [meddean.luc.edu]

• Abdominal Pain with Urination

  Information on health of the children and schistosomiasis infection Cough, abdominal pain, bloody urine (red urine), history of schistosomiasis, worm infestation, and abdominal problems had significantly higher odds of schistosomiasis infection than other [mmj.mw]

• Macroscopic Hematuria

  Figure 1 An eight-year-old boy was referred to the nephrology clinic with a two-year history of painless, gross macroscopic hematuria. [nejm.org]

Control is reliant on annual mass-treatment programmes, with little prospect of an anti-infection vaccine. [findaphd.com]

Each cohort will be examined before treatment and 2, 6 and 18 months after treatment. The study will be carried out in 4 primary schools; two from Machava J area and two from Costa do Sol area. [clinicaltrials.gov]

Few drugs are available for treatment of schistosomiasis. [parasitesandvectors.biomedcentral.com]

[…] weeks after treatment). [bmcinfectdis.biomedcentral.com]

mansoni and S. japonicum ) or the bladder ( S. haematobium ) → causes an immune response leading to inflammation and fibrosis Associated conditions squamous cell bladder cancer ( S. haematobium ) portal hypertension ( S. mansoni and S. japonicum ) Prognosis [medbullets.com]

The prognosis of schistosomiasisassociated PAH is not well understood and is likely very similar to that of idiopathic PAH. [phassociation.org]

What is the prognosis (outcome) for schistosomiasis? Early antiparasitic treatment, especially with acute schistosomiasis, may allow people to recover completely without developing chronic disease. [medicinenet.com]

If someone is also infected with malaria, HIV, or hepatitis, there is a worse prognosis. Can schistosomiasis be prevented? People who travel to areas affected by schistosomiasis should avoid exposure to fresh water that is likely to be contaminated. [patient.info]

The results of this thesis provide new leads for further research on disease etiology and underlying mechanisms in Schistosoma co-infections. [openaccess.leidenuniv.nl]

Schistosoma haematobiumis the etiologic agent for urogenital schistosomiasis, a major source of morbidity and mortality for more than 112 million people worldwide. [bio-protocol.org]

[…] necrosis and ulceration, followed by fibrosis with chronic inflammatory infiltrate Epidemiology Schistosoma haematobium infection is common in Africa and the Middle East, and is the world's leading cause of hematuria Uncommon in US, except in immigrants Etiology [pathologyoutlines.com]

Etiology: The trematodes (flukes). Schistosomes are flukes that inhabit the portal vascular system. All species have similar life cycles. [meddean.luc.edu]

Cancer 48: 2643–2648 CrossRef PubMed CAS Google Scholar Elsebai I (1977) Parasites in the etiology of cancer: bilharziasis and bladder cancer. [link.springer.com]

A community-wide study was carried out in a co-endemic focus in the north of Senegal, combining epidemiological, ecological, immunological, and geographical analyses. This multidisciplinary approach led to several new insights. [openaccess.leidenuniv.nl]

Egg output stability and the epidemiology of Schistosoma haematobium. Part II. An analysis of the epidemiology of S. haematobium. Transactions of the Royal Society of Tropical Medicine and Hygiene 67, 491–500.CrossRefGoogle Scholar Butterworth, A. [cambridge.org]

Epidemiological studies have suggested that host immunological factors may play an important role in co-endemic areas. [research.vu.nl]

The eggs are moved progressively toward the lumen of the bladder and ureters and are eliminated with urine. http://www.dpd.cdc.gov/dpdx/html/schistosomiasis.htm EPIDEMIOLOGY S. Haematobium is found in the Middle East, India, Portugal and Africa. [flipper.diff.org]

For many decades, researchers have attempted to infer properties of the immune response from epidemiological studies, with mathematical models frequently being used to bridge the gap between immunological theory and population-level data on schistosome [researchonline.lshtm.ac.uk]

Each disease-oriented section begins with an up-to-date review of pathophysiology and then focuses on specific diseases. [books.google.de]

Pathophysiology Infection with parasitic worms of the genus Schistosoma is responsible for causing schistosomiasis. [news-medical.net]

I: pathophysiology and diagnostic techniques. Neph Dial Transp 1999; 14: 2746-2753. 9. Latif, A.S. Urinogenital Infections in the Tropics (pp. 8.1–8.10). The Australasian College of Tropical medicine. 2004. [ispub.com]

[…] updated information on the extent of disease burden, communities at risk and factors associated with infection at the district and sub-district level to facilitate effective prioritization and monitoring while ensuring ownership and sustainability of prevention [ncbi.nlm.nih.gov]

Estimates show that at least 220.8 million people required preventive treatment in 2017. Preventive treatment, which should be repeated over a number of years, will reduce and prevent morbidity. [who.int]

Prevention Unclean water sources play an essential role in the life cycle of the parasitic worms and must be addressed to improve methods of prevention. [news-medical.net]

Methods: We designed a water recreation area (WRA) to prevent transmission to school-aged children. [iths.pure.elsevier.com]