CASE REPORTS Case 1 A 55-year-old white man (skin type IV) had a 10year history of general fatigue and progressive tightness and thickening of the skin of his upper and lower extremities and back. [kundoc.com]

The treatment was well tolerated with the exception of patient 2, who received a combination of penetrating photons and electron-beam therapy and who complained of a temporary sore throat, headache, and fatigue. [jamanetwork.com]

However, the patient treated with mixed photon therapy developed sore throat, nausea, fatigue, and headache during treatment. [appliedradiationoncology.com]

While the aggressive disease can be associated with constitutional symptoms such as profound fatigue and loss of weight, there is usually no visceral involvement. [indianjrheumatol.com]

A 55-yr-old white female with biopsy proven scleredema adultorum was evaluated for progressive dysphagia. [ncbi.nlm.nih.gov]

She then developed hoarseness of voice and progressive dysphagia. There was no history of cough, dyspnea, nasal regurgitation or gastroesophageal reflux. [ijdvl.com]

Am J Gastroenterol 1982 Jan;77(1):9-11 Abstract quote A 55-yr-old white female with biopsy proven scleredema adultorum was evaluated for progressive dysphagia. [thedoctorsdoctor.com]

No dysphasia or odynophagia nor constipation. No chest pain, palpitation or dyspnea. [shmabstracts.com]

No chest pain, palpitation or dyspnea. Examination revealed right hemiparesis non pitting, thickened, indurated, hard skin over the posterior neck, upper back and shoulder, chest and over the legs bilaterally with limited range of motion. [shmabstracts.com]

She had no history of an insect bite. Cutaneous examination revealed a well-defined erythematous, shiny, firm, non-tender plaque (measuring 3 cm X 4 cm) on the extensor surface of the lower third of her left forearm. [cyberleninka.org]

This specialist diagnosed a diabetes-related frozen shoulder and prescribed local corticosteroid injection followed by physiotherapy. [em-consulte.com]

No clinical evidence of proximal muscle weakness. With this clinical presentation, a provisional diagnosis of scleredema was made. [ijdvl.com]

Up to 9% of these patients can have arthralgias. [6] Unlike SSc, however, digital ulceration, nail fold capillary changes, Raynaud's phenomenon, resorption of phalanges, and internal organ involvement is very rare. [indianjrheumatol.com]

No dysphasia or odynophagia nor constipation. No chest pain, palpitation or dyspnea. [shmabstracts.com]

It is worthy to note that most of the cases in this series were previously unrecognised or neglected by MP or diabetologists. [em-consulte.com]

Serum protein electrophoresis was normal. Electrocardiogram, echocardiogram, chest X-Ray and HRCT of chest were normal. Anti nuclear antibodies, anti-topoisomerase-1, anticentromere antibodies and anti U 1 RNP were negative. [ijdvl.com]

Serum protein electrophoresis was normal. Electrocardiogram, echocardiogram, chest X-ray and HRCT of chest were normal. [cyberleninka.org]