Scoliosis is the lateral curvature and three dimensional rotation of the spinal column.
Scoliosis has characteristic physical findings. It presents as an abnormal shape and symmetry of the back, sometimes with either a very prominent rib or a bulging shoulder blade. Sometimes there may be a hump at the back. On examination, posture appears to be distorted and limb length may appear unequal. Ramirez and his coworkers from the Texas Scottish Rite Hospital studied more than 2400 patients with scoliosis and found that a full 23% (560 of 2442 patients) had back pain at the time of presentation . Some patients may also suffer from lung hypoplasia and compressed respiratory tree or other thoraco-abdominal organs.
A scoliometer may be used to diagnose the condition. Genetic testing may also be conducted, if needed. Tests may also include hematocrit and haemoglobin levels. Serum alkaline phosphatase levels and vitamin D levels may also be assessed.
On the basis of physical examination and imaging studies, scoliosis can be diagnosed and the extent of rotation can be assessed.
It mainly constitutes the use of braces, casts and analgesics. In a prospective, multicenter study from the Scoliosis Research Society, Nachemson and his coworkers found brace treatment (an underarm plastic brace worn for at least 16 h/d) to be successful 74% of the time (95% confidence interval [CI], 52-84%) . The results of a study conducted for infantile scoliosis patients suggest that body casting is useful in cases of smaller, flexible spinal curves, and vertical expandable prosthetic titanium rib
(VEPTR) is a viable alternative for larger curves .
Spinal fusion is the most commonly used surgical treatment. For a thoracic curve with adequate flexibility, posterior spinal fusion with instrumentation is used. If the curve is large and stiff, an anterior release including diskectomy and bone grafting is performed first. Large bone screws, pedicle screws and hooks are used to surgically derotate the spine. Endoscopic spinal instrumentation techniques have also been introduced and continue to evolve .
Scoliosis begins insidiously and persists for life unless surgically corrected. It is a chronic progressive disease and may prove to be fatal. Clinical outcomes following treatment of idiopathic scoliosis are strongly linked to curve magnitude . Mortality rate is associated with ‘curve effects’, meaning the distorted posture and curved spine may lead to damage of respiratory and cardiovascular organs. With appropriate treatment, mortality rate can be significantly reduced and quality of life can be substantially improved.
Idiopathic scoliosis is the most common type of spinal deformity confronting orthopedic surgeons . It has multifactorial causes, including genetics among which CHD7 gene is known to be involved. Congenital scoliosis is due to spinal malformation of the fetus between the 3rd and 6th week of development. Several neuromuscular diseases like poliomyelitis, cerebral palsy, spinomuscular atrophy, Ehlers Danlos syndrome, Marfan syndrome or neurofibromatosis may be the primary cause or associating disease in secondary or neuromuscular scoliosis.
Infantile scoliosis is a very rare condition with only 1% cases in North America. Idiopathic scoliosis on the other hand is a relatively common condition affecting 2-3% of the United States population, which is equivalent to about 5 to 9 million cases .
The prevalence of scoliosis was highest (1.2%) in patients aged 12-14 years .
In early-onset infantile scoliosis, 60% males are affected. In late-onset infantile scoliosis, 90% females are affected. In idiopathic scoliosis, females are at a greater risk.
The pathophysiology of scoliosis is still unclear. The spinal curvature that characterizes scoliosis may be due to malformation occurring during intrauterine development, resulting in infantile scoliosis. This type includes scoliosis appearing either at birth or within the first 3 years of life. Infantile scoliosis, along with genetic factors, is also associated with nursing posture and the side of deviation of the curve.
Neuromuscular scoliosis may be a result of other preexisting neuromuscular diseases such as Ehlers-Danlos syndrome, Marfan syndrome, neurofibromatosis, etc. The location is defined by the vertebra that is most deviated and rotated from midline, called the apical vertebra .
Whatever the type of scoliosis it may be, it is known that there are segments of the spinal column that are misaligned and these fusion defects result in the development of curvature of the spine to one side, which then progresses to three dimensional rotation and the resultant ‘S’ shaped spinal column.
Scoliosis may be prevented by maintaining correct posture and engaging in daily exercise and a healthy diet. Congenital scoliosis, however, has no known prevention but its progress can be halted or at least somewhat managed with appropriate treatment. Neuromuscular scoliosis can be prevented from occurring by adequately managing the underlying cause or associating disease with medication and physiotherapy.
Scoliosis is defined as a lateral curvature of the spine, most often than not accompanied by rotation. By convention, 10 degree of curvature (as measured by the Cobb angle) defines a scoliosis . Spinal curvatures that are of less than 10 degree are simply referred to as spinal asymmetry. On imaging, the spinal deformity appears to be of an ‘S’ shape. Scoliosis may be broadly classified into 3 types: Congenital, idiopathic and neuromuscular. All three are described below.
Scoliosis is defined as lateral or sideways curving and rotation of the spine. The curvature needs to be equal to or more than 10 degrees for the deformity to be classified as scoliosis. It may be present since birth, called infantile scoliosis or it may develop later on in life. The late-onset scoliosis is often a result of predisposing conditions.
The most common type of scoliosis is idiopathic, meaning it has no known cause. Neuromuscular scoliosis may be due to other diseases affecting the body’s structure. Infantile scoliosis is due to genetic factors and in some rare cases, it may be due to trauma during pregnancy.
Signs and symptoms
Scoliosis presents as abnormal shape and symmetry of the spine which may be accompanied with a hump and distorted posture. There may be protrusion of a rib or shoulder blade and unequal length of arms. Patients experience back pain which is exacerbated with movement and their physical activity becomes somewhat restricted.
Scoliosis can be conservatively managed with the help of casts and braces and painkillers. In severe cases, the curved spine may have to be corrected with the help of surgery which includes insertion of screws and rods to straighten the spine. Surgery is followed with physiotherapy to help relax and strengthen the muscles.