Presentation
[…] with presentation as late as 78 years have been described. [9] Once present, steatocystoma multiplex is a lifelong condition. [emedicine.com]
A lumen which is partly present in a few areas of the cord, is filled with the cellular debris of the keratinocytes, corneocytes, sebocytes, or the trapped hairs [ 4 ]. [ncbi.nlm.nih.gov]
Entire Body System
- Inflammation
Oral isotretinoin may further help reduce inflammation but doesn’t eradicate the cysts, study suggests. Intralesional steroids, oral retinoids, cryotherapy and carbondioxide lasers have been reported to reduce the inflammation with varying results. [dermatalk.com]
Pain, redness and inflammation are all indicative of an infection. Corticosteroids may be injected to reduce the inflammation. More often than not, the treatment involves the drainage of the contents of the closed sac. [buzzle.com]
There were no signs of inflammation in any one of the lesions. Other systems were normal and routine laboratory examination revealed no abnormality. Skin biopsy of the cystic nodule revealed histologic features suggestive of steatocystoma multiplex. [ijdvl.com]
Symptoms - Sebocystomatosis * Asymptomatic * Smooth skin swelling * Yellowish skin swelling * Inflammation * Suppuration * Dermoid cysts * Natal teeth Causes - Sebocystomatosis Not supplied. Prevention - Sebocystomatosis Not supplied. [checkorphan.org]
[…] other cases in the family). [1] [2] Some researchers have suggested that the condition may be a mild variant of pachyonychia congenita type 2. [3] Treatment may include minor surgery to remove cysts and oral antibiotics or oral isotretinoin to reduce inflammation [rarediseases.info.nih.gov]
- Fever
There was a history of low grade fever associated with pain and discharge from the left axillary swelling for the past 2 months. [jscisociety.com]
Musculoskeletal
- Arthritis
NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases Acrodermatitis Cradle cap Cryotherapy Cutaneous skin tags Dry skin Dry skin -- self-care Epidermolysis bullosa Erythema multiforme Erythema nodosum Erythema toxicum Granuloma annulare [icdlist.com]
[…] associated findings reported in patients with steatocystoma multiplex include ichthyosis, koilonychia, acrokeratosis verruciformis of Hopf, hyperkeratotic lichen planus, hidradenitis suppurativa, hypotrichosis, multiple keratoacanthomas and rheumatoid arthritis [ijdvl.com]
Steatocystoma multiplex has also been associated with ichthyosis, koilonychia, acrokeratosis, Verruciformis of Hopf, hypertrophic lichen planus, rheumatoid arthritis, hypohidrosis, hypothyroidism and hypotrichosis. [ijcasereportsandimages.com]
Hapalonychia may be attributed to myxedema, rheumatoid arthritis, bulimia, Hansens disease, Raynaud phenomenon, oral retinoid therapy, or radiodermatitis Muehrcke's nails Muehrckes nails, Muehrckes lines, or leukonychia striata are changes in the fingernail [wikivisually.com]
Skin
- Xanthoma
[…] pilaris Pyogenic granuloma Sebaceous cyst Seborrheic dermatitis Seborrheic keratosis Skin and hair changes during pregnancy Skin flaps and grafts -- self-care Skin graft Skin lesion biopsy Skin self-exam Stasis dermatitis and ulcers Striae Vesicles Xanthoma [icdlist.com]
Workup
X-Ray
- Nephrolithiasis
Showing of 4 | 80%-99% of people have these symptoms Adenoma sebaceum 0009720 Steatocystoma multiplex 0012035 5%-29% of people have these symptoms Nephrolithiasis Kidney stones 0000787 Percent of people who have these symptoms is not available through [rarediseases.info.nih.gov]
Treatment
Steatocystoma Multiplex Treatment & Management. Medscape Reference. 2016; http://emedicine.medscape.com/article/1059725-treatment. [rarediseases.info.nih.gov]
A variety of surgical treatment options have been used in the treatment of steatocystoma multiplex. Cryosurgery: Cryosurgery has been used in the past with limited success. Residual scarring limits this approach. [ipfs.io]
A review of the literature of this rare disease is included, and our method of treatment is described. [ncbi.nlm.nih.gov]
Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery 40(6): 658-662, 2014 Fractionated ablative carbon dioxide laser treatment of steatocystoma multiplex. [eurekamag.com]
Prognosis
Prognosis - Sebocystomatosis Prognosis of Steatocystoma multiplex - natal teeth: harmless permanent condition Treatment - Sebocystomatosis Not supplied. Resources - Sebocystomatosis Not supplied. [checkorphan.org]
The prognosis for patients with steatocystoma multiplex is excellent. No reports describe malignant transformation within these benign adnexal tumors. [emedicine.com]
Etiology
Etiology Steatocystoma multiplex is a disorder of the pilosebaceous unit that occurs in either a sporadic or an autosomal dominant fashion. [emedicine.com]
Etiology Sebocystomatosis is caused by mutations in the keratin-17 gene ( KRT17, 17q12-q21). Genetic counseling An autosomal dominant pattern of inheritance has been suggested. [orpha.net]
Epidemiology
Summary Epidemiology At least 30 cases from unrelated families (over three to five generations) and several sporadic cases have been reported. [orpha.net]
Clinical and epidemiological information in Mexico is scarce. OBJECTIVE: To describe the prevalence and demographic and clinical findings of eruptive vellous hair cysts confirmed by histopatological study. [ncbi.nlm.nih.gov]
The entry for each disease includes its epidemiology, laboratory findings, genetics, pathogenesis, cutaneous and extracutaneous findings, differential diagnosis, disease course, complications, and follow-up and therapy, where appropriate. [crcpress.com]
Androgenic stimulation of the sebaceous gland, along with environmental factors and the site and type of the keratin mutation, influence the onset of the sebaceous cysts. [3] Epidemiology Frequency Steatocystoma multiplex is considered rare [7] ; the [emedicine.com]
Pathophysiology
Pathophysiology Steatocystoma multiplex occurs as either a sporadic or autosomal dominant inherited condition characterized by benign sebaceous gland tumors. [emedicine.com]
Prevention
Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]
Prevention - Sebocystomatosis Not supplied. Diagnosis - Sebocystomatosis The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Steatocystoma multiplex - natal teeth. [checkorphan.org]
The KRT17 gene mutations that cause steatocystoma multiplex alter the structure of keratin 17, preventing it from forming strong, stable networks within cells. [ghr.nlm.nih.gov]
Journal of Cosmetic Dermatology 2018, 2018 Aspect mammographique de la sebocystomatose mammographic appearance of steatocystoma multiplex - Mammographic appearance of steatocystoma multiplex. le Sein (Paris) 5(3): 235-236, 1995 Comparison of the Scar Prevention [eurekamag.com]
This is to prevent it from getting infected. Make sure that you use oil-free skin care products. Under no circumstances should one squeeze it or scratch over it. [buzzle.com]