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Steatocystoma multiplex


  • […] with presentation as late as 78 years have been described. [9] Once present, steatocystoma multiplex is a lifelong condition.[emedicine.medscape.com]
  • A lumen which is partly present in a few areas of the cord, is filled with the cellular debris of the keratinocytes, corneocytes, sebocytes, or the trapped hairs [ 4 ].[ncbi.nlm.nih.gov]
  • A possibility of tubercular lymphadenitis with scrofuloderma was considered and fine-needle aspiration cytology was performed.[jscisociety.com]
  • For widespread lesion aspiration of the fluid with a syringe have been used with fairly successive results, though recurrence may be common.[dermatalk.com]
  • Aspiration: Simple aspiration with 18-gauge needle has been successful in minimizing scarring of facial lesions, although a high rate of recurrence has been observed.[ipfs.io]
  • Cutis 37: 115–120 PubMed Google Scholar Sato K, Shibuya K, Taguchi H, Kitano Y (1993) Aspiration therapy in steatocystoma multiplex.[link.springer.com]
  • Other procedures may include draining cysts through a procedure called aspiration, liquid nitrogen cryotherapy, dermabrasion, and carbon dioxide laser therapy. [1] [6] [11] [12] Laser treatments may be useful for patients with numerous cysts in whom removal[rarediseases.info.nih.gov]
  • Like steatocystoma multiplex, pachyonychia congenita involves the growth of steatocystomas.[ghr.nlm.nih.gov]
  • […] multiplex is simply a variant of pachyonychia congenita type 2 because they both share the same underlying etiology.[emedicine.medscape.com]
  • The associated findings reported in patients with steatocystoma multiplex include ichthyosis, koilonychia, acrokeratosis verruciformis of Hopf, hyperkeratotic lichen planus, hidradenitis suppurativa, hypotrichosis, multiple keratoacanthomas and rheumatoid[ijdvl.com]
  • Steatocystoma multiplex has also been associated with ichthyosis, koilonychia, acrokeratosis, Verruciformis of Hopf, hypertrophic lichen planus, rheumatoid arthritis, hypohidrosis, hypothyroidism and hypotrichosis.[ijcasereportsandimages.com]
  • Few authors have associated steatocystoma multiplex with ichthyosis and koilonychias, pachyonychia congenital, acrokeratosis verruciformis of hopf, hypertrophic lichen planus, hypohidrosis, hypothyroidism, hidradenitis suppurativa and hypotrichosis [[ncbi.nlm.nih.gov]
Nail Hypertrophy
  • Pachyonychia congenita is a rare hereditary disorder characterized mainly by nail hypertrophy and dyskeratosis of skin and mucous membrane PC-2 (Jackson–Lawler form) and is accompanied by steatocystoma multiplex. [7] Steatocystoma is considered as forme[ijcasereportsandimages.com]
Acneiform Eruption
  • Keywords Sebaceous Follicle Dermoid Cyst Alagille Syndrome Pilosebaceous Unit Acneiform Eruption These keywords were added by machine and not by the authors.[link.springer.com]
  • The relationship of steatocystoma multiplex to the development of sebaceous glands and common presentation at puberty suggest a hormonal trigger for lesion growth.[emedicine.medscape.com]
  • According to previous studies, androgenic stimulation and environmental factors have been suggested as the possible reasons ( 2, 3, 18 ).[ncbi.nlm.nih.gov]


  • Treatment options for steatocystoma multiplex are limited and have had varying degrees of success. The most effective treatment method is thought to be removal of cysts by surgery.[rarediseases.info.nih.gov]
  • A review of the literature of this rare disease is included, and our method of treatment is described.[ncbi.nlm.nih.gov]
  • A variety of surgical treatment options have been used in the treatment of steatocystoma multiplex. Cryosurgery: Cryosurgery has been used in the past with limited success. Residual scarring limits this approach.[ipfs.io]


  • Prognosis - Sebocystomatosis Prognosis of Steatocystoma multiplex - natal teeth: harmless permanent condition Treatment - Sebocystomatosis Not supplied. Resources - Sebocystomatosis Not supplied.[checkorphan.org]
  • The prognosis for patients with steatocystoma multiplex is excellent. No reports describe malignant transformation within these benign adnexal tumors.[emedicine.medscape.com]


  • Etiology Steatocystoma multiplex is a disorder of the pilosebaceous unit that occurs in either a sporadic or an autosomal dominant fashion.[emedicine.medscape.com]
  • Etiology Sebocystomatosis is caused by mutations in the keratin-17 gene ( KRT17 , 17q12-q21). Genetic counseling An autosomal dominant pattern of inheritance has been suggested.[orpha.net]


  • Summary Epidemiology At least 30 cases from unrelated families (over three to five generations) and several sporadic cases have been reported.[orpha.net]
  • Androgenic stimulation of the sebaceous gland, along with environmental factors and the site and type of the keratin mutation, influence the onset of the sebaceous cysts. [3] Epidemiology Frequency Steatocystoma multiplex is considered rare [7] ; the[emedicine.medscape.com]
Sex distribution
Age distribution


  • Pathophysiology Steatocystoma multiplex occurs as either a sporadic or autosomal dominant inherited condition characterized by benign sebaceous gland tumors.[emedicine.medscape.com]


  • The KRT17 gene mutations that cause steatocystoma multiplex alter the structure of keratin 17, preventing it from forming strong, stable networks within cells.[ghr.nlm.nih.gov]
  • Prevention - Sebocystomatosis Not supplied. Diagnosis - Sebocystomatosis The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Steatocystoma multiplex - natal teeth.[checkorphan.org]
  • Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates[icdlist.com]
  • Daily use of hand lotion or hand cream may help prevent the formation of hangnails, persistent hangnails should be evaluated by a physician. Hangnails can become infected and cause paronychia, a type of infection that occurs around the nails.[wikivisually.com]
  • This is to prevent it from getting infected. Make sure that you use oil-free skin care products. Under no circumstances should one squeeze it or scratch over it.[buzzle.com]

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