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Secondary Cardiomyopathy

Disease Secondary Myocardial


Presentation

  • We present a challenging case of a young man presenting with ischemic-looking electrocardiogram (ECG) changes, fever, hypotension, and global left ventricular hypokinesis.[radcliffecardiology.com]
  • Presentation symptomatology can be nausea, dizziness, anxiety, dyspnea and palpitations.[bmcresnotes.biomedcentral.com]
  • Aneurysmal subarachnoid hemorrhage may induce Takotsubo cardiomyopathy that can present as an acute ST-elevation myocardial infarction.[link.springer.com]
  • 10.1016/S1885-5857(09)73549-2 Baltasar Laínez a, Marina Ureña a, Virginia Álvarez a, Román Lezaun a a Servicio de Cardiología, Hospital de Navarra, Pamplona, Navarra, Spain Article To the Editor, Tako-Tsubo cardiomyopathy (TC) is a syndrome of clinical presentation[revespcardiol.org]
  • A53-year-old woman presented with progressive dyspnea. Family history was positive for Fabry’s disease. Cardiac MRI showed marked thickening of the left ventricle (Figure 1, arrow).[circ.ahajournals.org]
Congestive Heart Failure
  • heart failure. hypertrophic cardiomyopathy an increase in heart muscle weight, particularly of the left ventricle and often involving the interventricular septum; it may affect the flow of blood from an atrium into the ventricle or out from the ventricle[medical-dictionary.thefreedictionary.com]
  • Congestive heart failure in rickets caused by vitamin D deficiency. Monatsschr Kinderheilkd 1989 ; 137 : 108 – 110. 8. Kim, BG, Chang, SK, Kim, SM, Hwang, JS, Jung, JW.[cambridge.org]
  • Pulmonary team was consulted; the impression was consistent with pulmonary edema from questionable congestive heart failure (CHF), which could have been from the history of cocaine use rather than a primary pulmonary cause.[bmcresnotes.biomedcentral.com]
  • heart failure (chf) with cardiomyopathy Congestive heart failure due to cardiomyopathy Primary cardiomyopathy Secondary cardiomyopathy Tachycardia induced cardiomyopathy Clinical Information A disease of the heart muscle or myocardium proper.[icd10data.com]
  • Congestive Heart Failure This is a common feature of all late stage cardiomyopathies when the muscles of the heart become too weak to pump enough blood to the body for normal function.[childrenscardiomyopathy.org]
Intravenous Drugs
  • Other social history included occasional cigarette smoking, but no alcohol or intravenous drug use. He denied hazardous exposure.[bmcresnotes.biomedcentral.com]
Sputum
  • His other complaints included productive cough with whitish blood-tinged sputum, frontal headache, mild subjective fever and mid-sternal chest discomfort. Past medical history included only hypertension. No home medications were used.[bmcresnotes.biomedcentral.com]
Heart Disease
  • disease, and various chemicals and drugs.[medical-dictionary.thefreedictionary.com]
  • Understand Your Risk for Cardiomyopathy Symptoms and Diagnosis of Cardiomyopathy Prevention and Treatment of Cardiomyopathy Cardiomyopathy in Children Learn more: Family History and Heart Disease Alcohol and Heart Disease Cocaine, Marijuana and Other[heart.org]
  • Therefore, code 425.8 should be added to 414.8 (other specified forms of chronic ischemic heart disease) for ischemic cardiomyopathy. But it's ischemic heart disease. Wait a second.[hcpro.com]
  • Epidemiology In contrast to coronary heart disease having a higher incidence in the elderly, cardiomyopathies can occur at younger ages.[patient.info]
  • Familial and senile amyloid heart disease are related to the overproduction of transthyretin. Myocardial amyloid heart disease is confirmed by EMB.[clevelandclinicmeded.com]
Tachycardia
  • Dose-dependent tachycardia, hypertension along with increased arousal is the first physiological response to cocaine use.[bmcresnotes.biomedcentral.com]
  • The patient’s heart rate increased to 130bpm immediately after the intubation, with telemetry showing sinus tachycardia. An ECG was performed within one minute after intubation (see Figure 1 ).[radcliffecardiology.com]
  • With prolonged arrhythmias, the heartbeat may become either too fast (tachycardia) or too slow (bradycardia) and can occur in either the heart ventricles or atrial.[childrenscardiomyopathy.org]
  • Tachycardia-induced cardiomyopathy Pregnancy Peripartum cardiomyopathy 2003 The Cleveland Clinic Foundation.[clevelandclinicmeded.com]
  • […] heart muscle) Cardiomyopathy associated with another disorder Cardiomyopathy, primary (heart condition) Congestive heart failure (chf) with cardiomyopathy Congestive heart failure due to cardiomyopathy Primary cardiomyopathy Secondary cardiomyopathy Tachycardia[icd10data.com]
Cardiomegaly
  • Common abnormalities seen on the chest radiograph include cardiomegaly, interstitial edema, pleural effusion(s), and evidence of previous sternotomy (sternal wires).[clevelandclinicmeded.com]
Irregular Heart Rhythm
  • In some people, damage to the heart muscle due to cardiomyopathy can weaken the heart and lead to heart failure and dangerous irregular heart rhythms.[mydr.com.au]
Systolic Murmur
  • On examination he was hypertensive and tachycardic with a systolic murmur over the 5th intercostal space at the level of the left mid-clavicular line.[bmcresnotes.biomedcentral.com]
Muscle Spasticity
  • Citation American Heart Hospital Journal 2010;8(1):52-4 DOI Baclofen intrathecal infusion is frequently used to treat muscle spasticity of spinal or cerebral origin.[radcliffecardiology.com]

Workup

  • Initial laboratory workup at admission was insignificant except for elevated brain nautriuretic peptide of 894 ng/L and positive urine toxicology screen for cocaine.[bmcresnotes.biomedcentral.com]
  • The term "idiopathic" means that the physician cannot determine the cause of the cardiomyopathy despite extensive workup. If the physician can determine the cause, then by definition it's secondary cardiomyopathy.[hcpro.com]
Incomplete Right Bundle Branch Block
  • A previous ECG (two years ago) showed incomplete right bundle branch block morphology but no other abnormality.[radcliffecardiology.com]
T Wave Inversion
  • These may include electrocardiogram (ECG) changes of QT prolongation and T wave inversion, elevated biochemical markers of myocardial damage and heart failure, and decreased left ventricular function [ 1 ]-[ 3 ].[link.springer.com]

Treatment

  • Non-invasive testing should be performed after several months to re-evaluate the treatment response.[bmcresnotes.biomedcentral.com]
  • Khorasani A, Peruzzi WT, Dantrolene treatment for abrupt intrathecal baclofen withdrawal, Aneth Analg, 1995;80:1054–6.[radcliffecardiology.com]
  • Physicians need to be aware of this possibility since it can lead to significant delays and treatment options for the patient.[link.springer.com]
  • Each infant required IV calcium for up to 5 days with subsequent oral calcium treatment. They were all treated with oral vitamin D for between 6 and 12 months.[imj.ie]
  • Some people will not need any treatment. Treatment of secondary cardiomyopathy may involve treating the underlying condition.[mydr.com.au]

Prognosis

  • These patients had a poor short term prognosis (p 0.001).[ncbi.nlm.nih.gov]
  • Apical and mid-ventricular transient left ventricular dysfunction syndrome (Tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis. Chest. 2007;132: 809-16. Medline 5.[revespcardiol.org]
  • Given the patient's poor prognosis when she arrived, it is unclear if the heparin she received during cardiac catheterization worsened her SAH or changed her outcome.[link.springer.com]
  • Identification of these areas and restoration of their perfusion through revascularization might improve the ejection fraction and long-term prognosis.[clevelandclinicmeded.com]
  • A semiquantitative measure of cardiac involvement that improves prediction of prognosis in systemic sclerosis Arthritis Rheum, 34 (1991), pp. 1371-1380 [4.] F.M. Wigley, L.K.[reumatologiaclinica.org]

Etiology

  • […] of abnormal substances, as may occur in amyloidosis, hemochromatosis, and other disorders. primary cardiomyopathy that in which the basic pathologic process involves the myocardium itself and not other cardiac structures; the condition is of unknown etiology[medical-dictionary.thefreedictionary.com]
  • Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.[icd10data.com]
  • Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive. [ NCIT : C34830 ] Synonyms: extrinsic cardiomyopathy, [X]Cardiomyopathy in other[ebi.ac.uk]
  • These mechanisms may be responsible for the etiology for the TCM that occurred in our patient. TCM most commonly occurs in women (89%) with a mean age of 68. Forty-six percent of cases are triggered by intense emotional or physical stress.[link.springer.com]
  • Our differential included an etiology causing pulmonary edema versus a less likely pulmonary hemorrhage or atypical infection. Figure 1 Chest X-ray- bilateral patchy opacities.[bmcresnotes.biomedcentral.com]

Epidemiology

  • Vitamin-D concentrations, cardiovascular risk and events - a review of epidemiological evidence . Reviews in Endocrine and Metabolic Disorders, Vol. 18, Issue. 2, p. 259.[cambridge.org]
  • Epidemiology In contrast to coronary heart disease having a higher incidence in the elderly, cardiomyopathies can occur at younger ages.[patient.info]
  • […] cardiomyopathy, contact the Children’s Cardiomyopathy Foundation listed in the Resources section of this report or the National Institutes of Health (NIH) clinical trials web site: The Pediatric Cardiomyopathy Registry was established to describe the epidemiologic[rarediseases.org]
Sex distribution
Age distribution

Pathophysiology

  • PubMed View Article Google Scholar Abraham JR, Butany J, Leong S, Luk A, Phillips K, Soor GS: Cocaine cardiotoxicity a review of the pathophysiology, pathology, and treatment options. Am J Cardiovasc Drugs. 2009, 9 (3): 177-196. 10.1007/BF03256574.[bmcresnotes.biomedcentral.com]
  • Further studies are needed in order to understand the pathophysiology and mechanism of cardiomyopathy associated with baclofen withdrawal syndrome.[radcliffecardiology.com]
  • Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.[icd10data.com]
  • Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive. [ NCIT : C34830 ] Synonyms: extrinsic cardiomyopathy, [X]Cardiomyopathy in other[ebi.ac.uk]
  • Additionally, arrhythmias and chest pain may be present. [10] The pathophysiology of cardiomyopathies is better understood at the cellular level with advances in molecular techniques.[en.wikipedia.org]

Prevention

  • Global Consensus Recommendations on Prevention and Management of Nutritional Rickets. J Clin Endcorinol Metab, February 2016, 101 (2):394-415 3. Maiya S.[imj.ie]
  • Vitamin D and cardiovascular disease prevention . Nature Reviews Cardiology, Vol. 13, Issue. 7, p. 404. CrossRef Google Scholar Reid, Ian R 2016. What diseases are causally linked to vitamin D deficiency? .[cambridge.org]
  • Is It Possible to Prevent Cardiomyopathy? Cardiomyopathy is a term that describes the end result of many diseases and illnesses.[emedicinehealth.com]
  • Prevention In many cases, cardiomyopathy cannot be prevented. However, there are some types of cardiomyopathy that can be avoided, such as those that are caused by excessive alcohol or drug use.[mydr.com.au]
  • .: Specific inhibitors and promoters of calcium action in the excitation-contraction coupling of heart muscle and their role in the prevention or production of myocardial lesions. In Calcium and the Heart, ed. ‎[books.google.es]

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