Presentation
Despite radiotherapy, the CNS disease progressed, and the patient died 19 months after the presentation. [ncbi.nlm.nih.gov]
Entire Body System
- Severe Pain
Here, the eye's drainage system gets suddenly blocked, swelling and reddening the affected eye and causing acute severe pain that often comes with nausea, diminished vision (central and side), and perceived halos around lights. [eyespecialists.org]
pain and blurring of vision following any intraocular operation 27. On examination, Persistent flat anterior chamber Markedly raised IOP Unresponsiveness or even aggravation by miotics Phakic, aphakic or pseudophakic Treatment – Medical [slideshare.net]
While each person may experience symptoms differently, they may include: Blurred or narrowed field of vision Severe pain in the eye(s) Haloes (which may appear as rainbows) around lights Nausea Vomiting Headache The symptoms of acute angle-closure glaucoma [ohsu.edu]
You should call your doctor immediately if you begin experiencing symptoms, such as severe pain, nausea, and blurred vision. [healthline.com]
If you have severe eye pain or a sudden loss of vision, get immediate medical help. These may be signs of closed-angle glaucoma. You cannot prevent open-angle glaucoma. Most people have no symptoms. But you can help prevent vision loss. [medlineplus.gov]
- Fatigue
He also complained of having fatigue, general weakness, and disequilibrium. His visual acuity was 20/20 bilaterally. His intraocular pressures were 34 mm Hg oculus dexter (OD) and 35 mm Hg oculus sinister (OS). [ncbi.nlm.nih.gov]
[…] elongated and thickened eyelashes; muscle, joint, and back pain; skin rash; red eyes Given as eye drops, prostaglandin-like compounds increase the aqueous humor outflow Alpha-agonists ApraclonidineBrimonidineDipivefrinEpinephrine Dry nose and mouth; fatigue [eyehealthweb.com]
A common side effect of oral medications is fatigue. Medication requires regular use to keep eye pressure under control. [hartzelleye.com]
Beta-blockers Timolol Betaxolol Carteolol Levobetaxalol Levobunolol Metipranolol Shortness of breath in people with asthma or other lung disorders that cause wheezing Slow heart beat Insomnia Fatigue Depression Confusion Sexual dysfunction See table: [merckmanuals.com]
However, side effects, such as the worsening of asthma or emphysema, bradycardia (slow heart rate), low blood pressure, fatigue, and impotence prohibit their use in some patients. [medicinenet.com]
- Short Stature
Weill-Marchesani syndrome (WMS) is a rare systemic connective tissue disorder with the systemic features of short stature, short and stubby hands and feet and stiff joints, especially in the hands. [ncbi.nlm.nih.gov]
Gastrointestinal
- Nausea
In the latter, the symptoms are those of acute glaucoma : ocular pain, which can extend to the nape of the neck and trigeminal, blurred vision, pupil dilation, change in iris colour, corneal hardening, nausea and vomiting, etc. [fernandez-vega.com]
[…] not demonstrate any signs of, or be related to various symptoms: photophobia, tearing eyes appearing repeatedly, the appearance of gloom or rainbow wheels when looking at the sources of light, vision problems in the dark, eye pain, often very strong, nausea [health-factbook.com]
Symptoms can include sudden eye pain, nausea, headaches, and blurred vision. If you experience these symptoms, you should seek immediate medical treatment. [visionaware.org]
Symptoms include headache, intense eye pain, blurred vision, nausea, vomiting, and halos. [docshop.com]
You should call your doctor immediately if you begin experiencing symptoms, such as severe pain, nausea, and blurred vision. [healthline.com]
Cardiovascular
- Vascular Disease
However, these fistulas may be congenital arteriovenous connections that open spontaneously in the settings of collagen vascular disease, atherosclerosis, hypertension, or may develop in females during peripartum period. [ncbi.nlm.nih.gov]
Secondary Glaucoma Secondary glaucoma occurs as a result of an eye injury, inflammation, tumor, cataracts, diabetes or vascular disease. Sometimes, medications such as steroids can cause secondary glaucoma. [associatedeyecare.com]
These secondary glaucomas cause a reduction in outflow of aqueous humour, caused by inflammatory debris, intraocular haemorrhage and growth of new blood vessels in the angle (neovascular glaucoma) resulting from ocular vascular diseases of the eye [ 13 [patient.info]
Eyes
- Blurred Vision
A 33-year-old woman experienced blurred vision in her left eye. Intraocular pressure of the left eye was elevated accompanied with a very shallow anterior chamber. [ncbi.nlm.nih.gov]
Sudden visual disturbance Blurred vision Halos around lights Red eyes Headache Either type of glaucoma can be primary or secondary disorder. [hartzelleye.com]
In the latter, the symptoms are those of acute glaucoma : ocular pain, which can extend to the nape of the neck and trigeminal, blurred vision, pupil dilation, change in iris colour, corneal hardening, nausea and vomiting, etc. [fernandez-vega.com]
If you do notice any symptoms, they might include blurred vision, or seeing rainbow-coloured circles around bright lights. Both eyes are usually affected, although it may be worse in one eye. [nhs.uk]
- Corneal Opacity
However, at 14 months old, the left eye showed moderate corneal opacity with a band keratopathy. [ncbi.nlm.nih.gov]
It was interesting that the remaining three patients with no ocular episode had no corneal opacity, but had corneal neovascularization that might have been caused by keratitis. [omicsonline.org]
In our study, 5 phakic eyes of corneal abscess were rendered aphakic, 3 corneal opacity cases phakic to pseudophakic, 2 failed graft cases phakic to aphakic, and 1 descematocoel case phakic to pseudophakic. [jcor.in]
- Lacrimation
The aqueous humor should not be confused with tears, which are produced by the lacrimal glands under the upper eyelid outside of the eyeball itself. [medicinenet.com]
- Visual Acuity Decreased
For one of these three eyes, visual acuity decreased to no light perception. But the remaining two eyes maintained better than 20/100 visual acuity, according to the study. [healio.com]
- Peripheral Vision Loss
If not treated, it can lead to severe vision loss or even blindness. Glaucoma is usually (but not always) associated with high intraocular pressure, and begins with a loss of peripheral vision. [eyehealthweb.com]
Neurologic
- Headache
[…] related to various symptoms: photophobia, tearing eyes appearing repeatedly, the appearance of gloom or rainbow wheels when looking at the sources of light, vision problems in the dark, eye pain, often very strong, nausea, abdominal pain, vomiting, headaches [health-factbook.com]
Symptoms can include sudden eye pain, nausea, headaches, and blurred vision. If you experience these symptoms, you should seek immediate medical treatment. [visionaware.org]
Symptoms include headache, intense eye pain, blurred vision, nausea, vomiting, and halos. [docshop.com]
Some people may have eye redness, discomfort, blurred vision, or a headache that lessens with sleep. The eye pressure may be normal but usually is higher in the affected eye. [merckmanuals.com]
[…] vision Gradual loss of peripheral vision Tunnel vision (at advanced stages) The symptoms of angle-closure glaucoma can be eye-related or systemic: Severe eye pain Nausea and vomiting Sudden visual disturbance Blurred vision Halos around lights Red eyes Headache [hartzelleye.com]
Workup
A systemic workup at that time (including computed tomography and bone scans) was negative for any signs of malignancy. [glaucomatoday.com]
Treatment
Patients underwent a mean of 2.15 treatment sessions per eye. Pretreatment intraocular pressure (IOP) was 30.2 (5.5) mm Hg before the first treatment, 30.5 (5.7) mm Hg before the second treatment, and 28.7 (6.3) mm Hg before the third treatment. [ncbi.nlm.nih.gov]
Prognosis
To study the frequency of ocular manifestations and the prognosis of secondary glaucoma in cases of carotid-cavernous fistula (CCF). [ncbi.nlm.nih.gov]
Prognosis Prognosis in secondary congenital glaucoma is guarded. Earlier age at onset of glaucoma usually is more difficult to manage. Patients need multiple procedures, each of which has its own risks. [emedicine.medscape.com]
Etiology
OBJECTIVE: Knowing and understanding the etiology and pathogenesis of neovascular secondary glaucoma. METHODS AND RESULTS: Review of the angiogenesis theory to understand the etiology and pathogenesis of neovascular secondary glaucoma. [ncbi.nlm.nih.gov]
Cases:The presenet series comprised a 62-year-old male with ocular sarcoidosis,a 74-year-old female with uveitis of unknown etiology,and a 55-year-old male with Fuchs heterochromic iridocyclitis. All had glaucoma in one eye. [webview.isho.jp]
Etiology See Pathophysiology section below. [eyewiki.aao.org]
Epidemiology
DESIGN: Population-based epidemiological survey. PARTICIPANTS: A random sample of residents 40 years or older from Tajimi, Japan. [ncbi.nlm.nih.gov]
Keywords: clinical (human) or epidemiologic studies: outcomes/complications • trauma • intraocular pressure © 2012, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. [iovs.arvojournals.org]
Aspects of epidemiology, pathogenesis and therapy. Dev Ophthalmol 1999; 30 : 91–109. 2. Okhravi N, Odufuwa B, McCluskey P, Lightman S. Scleritis. Surv Ophthalmol 2005; 50 (4): 351–363. 3. Wilhelmus KR, Grierson I, Watson PG. [nature.com]
[…] iris syndrome Uveal edema (scleral buckling, panretinal photocoagulation, central retinal vein occlusion) Retrolenticular tissue contracture (persistent hyperplastic primary viterous, retinopathy of prematurity) The ISGEO classification of Glaucoma for Epidemiological [epomedicine.com]
Epidemiology Frequency United States Aniridia is rare, occurring in 1.8 per 100,000 live births; 50% of these patients develop glaucoma. [emedicine.medscape.com]
Pathophysiology
Amyloid associated with glaucoma may involve different pathophysiologic mechanisms. The elevated IOP may not respond well to medical therapy. Cautious surgical manipulation of the conjunctiva is warranted in these cases. [ncbi.nlm.nih.gov]
Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome. Int Ophthalmol. 2018 Feb. 38 (1):409-416. [Medline]. Kargi SH, Koc F, Biglan AW, Davis JS. Visual acuity in children with glaucoma. [emedicine.medscape.com]
Pathophysiology of glaucoma [ 3, 4 ] The primary problem in glaucoma is disease of the optic nerve. The pathophysiology is not fully understood, but there is a progressive loss of retinal ganglion cells and their axons. [patient.info]
Prevention
Treatment results were regarded as successful when secondary angle-closure glaucoma was prevented or responded to treatment. RESULTS: The mean age of those who underwent external SRFD was 3.1+/-1.8 years. [ncbi.nlm.nih.gov]