Presentation
The cause underlying this clinical presentation was identified as the chronic pressure brought forward by the cavernous hemangioma. [ncbi.nlm.nih.gov]
ICD Code ICD Description Total National Projected Hospitalizations - Annualized (Present on Admission - All) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - All) Total National Projected Hospitalizations - Annualized (Present [dexur.com]
This case report was presented before at AOPMC 2016, Manila. It has not been published yet. To cite this abstract in AMA style: D. Desai, S. Desai. Rare presentation of acute secondary parkinsonism in the post partum period. [abstract]. [mdsabstracts.org]
Results: Not applicable Conclusions: We present an interesting case of large anterior cranial fossa meningioma with mass effect on the caudate presenting with secondary parkinsonism. [n.neurology.org]
Entire Body System
- Weakness
The patient returned, complaining of generalized weakness. The ED workup this time, comprising laboratory testing and computed tomography of the abdomen and pelvis, was negative. She was given a diagnosis of “cisplatin neurotoxicity.” [mdedge.com]
Common symptoms include: Decrease in facial expressions Difficulty starting and controlling movement Loss or weakness of movement (paralysis) Soft voice Stiffness of the trunk, arms, or legs Tremor Confusion and memory loss may be likely in secondary [salud.wikiplus.org]
History of episodes of inability to talk, weakness of the body These features usually suggest underlying cause for secondary parkinsonism such as stroke. They may give a history of strokes and transient ischemic attacks. [medicaljoyworks.com]
- Pain
Joint pain Patients with PD can develop joint pain due to muscle rigidity. Joint pain Patients with PD can develop joint pain due to muscle rigidity. Postural deformities As the disease progresses patients develop postural deformities. [medicaljoyworks.com]
A pre-parkinsonian state is recognized with insomnia, increase in violent dreams, talking, yelling in sleep. [1] [2] Olfactory dysfunction, Oral pain, akathisia, genital pain [2] These are pre-parkinsonism features and thought to be due to neuronal loss [explainmedicine.com]
Her primary complaints in the ED were “throbbing” in the thighs bilaterally and leg pain. The woman’s postop course had otherwise been uncomplicated. [mdedge.com]
- Rigor
URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. [leehealth.org]
Psychiatrical
- Withdrawn
Symptoms begin after the use of the offending drug and usually resolve after the drug is being withdrawn. [medicaljoyworks.com]
Drug-induced parkinsonism (DIP) can be difficult to diagnose; it is often missed by clinicians (even by neurologists).1 This is regrettable, because DIP is usually reversible once the offending agent is withdrawn. [mdedge.com]
† When drugs are withdrawn, symptoms usually resolve within a few weeks, although they may persist for months. ‡ N-MPTP results from unsuccessful attempts to produce meperidine for illicit use. [msdmanuals.com]
Neurologic
- Confusion
Side effects include hallucinations, confusion, dizziness and headaches. [livestrong.com]
Common symptoms include: Decrease in facial expressions Difficulty starting and controlling movement Loss or weakness of movement (paralysis) Soft voice Stiffness of the trunk, arms, or legs Tremor Confusion and memory loss may be likely in secondary [salud.wikiplus.org]
When to Contact a Medical Professional Call the provider if: Symptoms of secondary parkinsonism develop, come back, or get worse New symptoms appear, including confusion and movements that cannot be controlled You are unable to care for the person at [health.firstlighthealthsystem.org]
Symptoms Common symptoms include: Decrease in facial expressions Difficulty starting and controlling movement Loss or weakness of movement (paralysis) Soft voice Stiffness of the trunk, arms, or legs Tremor Confusion and memory loss may be likely in secondary [irmcphysicians.com]
- Cogwheel Rigidity
The cogwheel rigidity improved post-resection, but she continued to have a mild right-handed resting tremor without further progression of disease. [n.neurology.org]
Neurological examination revealed left hemiparkinsonism, characterised by mixed tremor (postural, action and intermittent rest tremor) in both extremities, hypomimia, bradykinesia, cogwheel rigidity and loss of arm swing during gait on the left hand side [jnnp.bmj.com]
[…] as "cogwheel rigidity". [medicaljoyworks.com]
She drooled, and had dysarthria, a shuffling gait, and cogwheel rigidity. Medications included metoclopramide, three times daily; prochlorperazine, every 6 hours; omeprazole; and dexamethasone. [mdedge.com]
- Irritability
These often include the following: Fatigue or general malaise Trembling Difficulty arising from a seated position Lowered voice volume (dysarthria) Small, cramped, spidery handwriting Losing track of a word or thought Irritability or sadness for no apparent [columbianeurosurgery.org]
Higher cortical functions Apraxia (limb more common than orofacial, eyelid- opening) Dementia Alien-limb phenomenon Aphasia Frontal-lobe-release signs Cortical sensory abnormalities Depression apathy Anxiety Irritability Disinhibition [slideshare.net]
Workup
The ED workup this time, comprising laboratory testing and computed tomography of the abdomen and pelvis, was negative. She was given a diagnosis of “cisplatin neurotoxicity.” No treatment was provided. [mdedge.com]
Treatment
Incorrect diagnoses of depression or catatonia delayed treatment or aggravated the problem. Acute treatment included amantadine, levodopa/carbidopa with or without selegiline, diphenhydramine, or benztropine. [ncbi.nlm.nih.gov]
Our understanding of the pathogenic mechanisms and our treatment options are expanding at a rapid pace. [books.google.de]
There are no specific treatments for DLB. Treatment focuses on symptoms. Drug-induced Parkinsonism This is the most common form of what is known as secondary parkinsonism. [parkinson.org]
For a more detailed description of treatment, see Parkinson's disease. [sites.magellanhealth.com]
Treatment Return to top Treatment is aimed at controlling symptoms. If the symptoms are mild, no treatment may be needed. If the condition is caused by a medication, the benefits of the medication should be weighed against the severity of symptoms. [pacificschoolserver.org]
Prognosis
Outlook (Prognosis) Unlike Parkinson disease, some types of secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Some brain problems, such as Lewy body disease, are not reversible. [health.firstlighthealthsystem.org]
Outlook (Prognosis) Unlike Parkinson disease, secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Brain problems, such as Lewy body disease, are not reversible. [irmcphysicians.com]
Outlook (Prognosis) Unlike Parkinson disease, some types of secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Brain problems, such as Lewy body disease, are not reversible. [stelizabeth.com]
Etiology
Etiologies included hypoxic-ischemic encephalopathy; haloperidol treatment with and without neuroleptic malignant syndrome; toxicity of cytosine arabinoside, cyclophosphamide, amphotericin B, and methotrexate; St. [ncbi.nlm.nih.gov]
Etiology Parkinson disease: PD is commonly considered idiopathic, although several etiologic factors (e.g., genetic predisposition) are being investigated. [amboss.com]
Secondary parkinsonism can be due to metabolic disorders, intoxication, cerebrovascular disorders, head injuries, or infectious etiologies. Intracranial tumor is an established, but rare cause of secondary parkinsonism. [n.neurology.org]
However, a wide range of other etiologies may lead to a similar set of symptoms, including some toxins, a few metabolic diseases, and a handful of neurological conditions other than Parkinson's. [icd.codes]
To date, the etiology of MSA is still elusive, yet a complex interaction incorporating genetic predisposition and environmental factors is suggested to drive disease initiation and progression, as familial aggregation following an autosomal dominant or [movementdisorders.org]
Epidemiology
Epidemiology of Parkinson's disease. Lancet Neurol 2006;5:525-535. 2. Alves G, Forsaa EB, Pedersen KF, Dreetz Gjerstad M, Larsen JP. Epidemiology of Parkinson's disease. J Neurol 2008;255 Suppl 5:18-32. 3. [jkna.org]
Parkinson disease: parkinsonism for which no cause can be determined (idiopathic) References:[1][2] Epidemiology References:[1][3][4][5][6][7] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Author information 1 Dipartimento di Scienze Neurologiche, Sapienza Università di Roma, Rome, Italy. [email protected] Abstract The PRIAMO study is a cross-sectional longitudinal observational study aimed at describing epidemiology and evolution [ncbi.nlm.nih.gov]
Epidemiologic approaches to the study of Parkinson's disease etiology. Epidemiology 1999; 10: 327-336. 13. Tanner CM, Aston DA. Epidemiology of Parkinson's disease and akinetic syndromes. Curr Opin Neurol 2000; 13: 427-430. 14. Calne DB. [ge-bu.nl]
Epidemiology : prevalence of MSA in four studies ranged from 1·9 to 4·9 cases per 100 000 people. similar to those of other well-known neurodegenerative disorders such as Huntington’s disease and motor neuron disease. no single environmental [slideshare.net]
Pathophysiology
Furthermore, they illustrate the metabolic effects related to acute focal lesions of the SN as opposed to the progressive degeneration in idiopathic PD and may serve to help unravel the complicated pathophysiology underlying these conditions. [ncbi.nlm.nih.gov]
Clinical expressions, postulated pathophysiological mechanisms and responsiveness to antiparkinson medication represent differences between IPD and secondary Parkinsonism (SP). OBJECTIVES: To evaluate NMS expressions in IPD, SP and a control group. [clinicaltrials.gov]
We discuss the pathophysiology leading to involvement of substantia nigra and treatment options. [content.iospress.com]
Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder. Dialogues Clin Neurosci. 2004 Sep; 6(3): 259–280. Gazewood JD, Richards DR, Clebak K. Parkinson disease: an update. [parkinsonsdisease.net]
Prevention
People taking medicines that can cause secondary parkinsonism should be carefully monitored by the provider to prevent the condition from developing. [health.firstlighthealthsystem.org]
People taking medicines that can cause secondary parkinsonism should be carefully monitored by the doctor to prevent the condition from developing. References Lang AE. Parkinsonism. In: Goldman L, Schafer AI. [irmcphysicians.com]
Treating underlying conditions, such as stroke or infections, can reduce symptoms or prevent the condition from getting worse. If symptoms make it hard to do everyday activities, the provider may recommend medicine. [stelizabeth.com]