Presentation
The cause underlying this clinical presentation was identified as the chronic pressure brought forward by the cavernous hemangioma. [ncbi.nlm.nih.gov]
ICD Code ICD Description Total National Projected Hospitalizations - Annualized (Present on Admission - All) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - All) Total National Projected Hospitalizations - Annualized (Present [dexur.com]
This case report was presented before at AOPMC 2016, Manila. It has not been published yet. To cite this abstract in AMA style: D. Desai, S. Desai. Rare presentation of acute secondary parkinsonism in the post partum period. [abstract]. [mdsabstracts.org]
Results: Not applicable Conclusions: We present an interesting case of large anterior cranial fossa meningioma with mass effect on the caudate presenting with secondary parkinsonism. [n.neurology.org]
Entire Body System
-
Weakness
The patient returned, complaining of generalized weakness. The ED workup this time, comprising laboratory testing and computed tomography of the abdomen and pelvis, was negative. She was given a diagnosis of “cisplatin neurotoxicity.” [mdedge.com]
Common symptoms include: Decrease in facial expressions Difficulty starting and controlling movement Loss or weakness of movement (paralysis) Soft voice Stiffness of the trunk, arms, or legs Tremor Confusion and memory loss may be likely in secondary [salud.wikiplus.org]
History of episodes of inability to talk, weakness of the body These features usually suggest underlying cause for secondary parkinsonism such as stroke. They may give a history of strokes and transient ischemic attacks. [medicaljoyworks.com]
-
Pain
Olfactory dysfunction, Oral pain, akathisia, genital pain These are pre-parkinsonism features and thought to be due to neuronal loss in the corticomedial amygdala or to decreased dopaminergic neurons in the olfactory bulb. [medicaljoyworks.com]
A pre-parkinsonian state is recognized with insomnia, increase in violent dreams, talking, yelling in sleep. [1] [2] Olfactory dysfunction, Oral pain, akathisia, genital pain [2] These are pre-parkinsonism features and thought to be due to neuronal loss [explainmedicine.com]
Her primary complaints in the ED were “throbbing” in the thighs bilaterally and leg pain. The woman’s postop course had otherwise been uncomplicated. [mdedge.com]
Gastrointestinal
-
Polydipsia
He improved significantly with levodopa therapy.Psychogenic polydipsia is an important cause of hyponatraemia. Overzealous correction of hyponatraemia can be counterproductive. [ncbi.nlm.nih.gov]
Psychogenic polydipsia is an important cause of hyponatraemia. Overzealous correction of hyponatraemia can be counterproductive. [casereports.bmj.com]
Neurologic
-
Altered Mental Status
Altered mental status, mutism, dysphagia, and sialorrhea were frequent associations. [ncbi.nlm.nih.gov]
-
Spastic Quadriplegia
The central basis pontis is the most common area affected and the resulting clinical syndrome, commonly called central pontine myelinolysis, is characterized by confusion, horizontal gaze paralysis, and spastic quadriplegia. [esim.eg.net]
Workup
The ED workup this time, comprising laboratory testing and computed tomography of the abdomen and pelvis, was negative. She was given a diagnosis of “cisplatin neurotoxicity.” No treatment was provided. [mdedge.com]
Treatment
Incorrect diagnoses of depression or catatonia delayed treatment or aggravated the problem. Acute treatment included amantadine, levodopa/carbidopa with or without selegiline, diphenhydramine, or benztropine. [ncbi.nlm.nih.gov]
Our understanding of the pathogenic mechanisms and our treatment options are expanding at a rapid pace. [books.google.de]
There are no specific treatments for DLB. Treatment focuses on symptoms. Drug-induced Parkinsonism This is the most common form of what is known as secondary parkinsonism. [parkinson.org]
Prognosis
Outlook (Prognosis) Unlike Parkinson disease, some types of secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Some brain problems, such as Lewy body disease, are not reversible. [health.firstlighthealthsystem.org]
Outlook (Prognosis) Unlike Parkinson disease, secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Brain problems, such as Lewy body disease, are not reversible. [irmcphysicians.com]
Outlook (Prognosis) Unlike Parkinson disease, some types of secondary parkinsonism may stabilize or even improve if the underlying cause is treated. Brain problems, such as Lewy body disease, are not reversible. [stelizabeth.com]
Etiology
Etiologies included hypoxic-ischemic encephalopathy; haloperidol treatment with and without neuroleptic malignant syndrome; toxicity of cytosine arabinoside, cyclophosphamide, amphotericin B, and methotrexate; St. [ncbi.nlm.nih.gov]
However, a wide range of other etiologies may lead to a similar set of symptoms, including some toxins, a few metabolic diseases, and a handful of neurological conditions other than Parkinson's. [icd.codes]
Secondary parkinsonism can be due to metabolic disorders, intoxication, cerebrovascular disorders, head injuries, or infectious etiologies. Intracranial tumor is an established, but rare cause of secondary parkinsonism. [n.neurology.org]
CONSUMERS: Click here for the Consumer Version Topic Resources Secondary parkinsonism refers to a group of disorders that have features similar to those of Parkinson disease but have a different etiology. [msdmanuals.com]
To date, the etiology of MSA is still elusive, yet a complex interaction incorporating genetic predisposition and environmental factors is suggested to drive disease initiation and progression, as familial aggregation following an autosomal dominant or [movementdisorders.org]
Epidemiology
Author information 1 Dipartimento di Scienze Neurologiche, Sapienza Università di Roma, Rome, Italy. [email protected] Abstract The PRIAMO study is a cross-sectional longitudinal observational study aimed at describing epidemiology and evolution [ncbi.nlm.nih.gov]
Epidemiology of Parkinson's disease. Lancet Neurol 2006;5:525-535. 2. Alves G, Forsaa EB, Pedersen KF, Dreetz Gjerstad M, Larsen JP. Epidemiology of Parkinson's disease. J Neurol 2008;255 Suppl 5:18-32. 3. [jkna.org]
Parkinson disease: parkinsonism for which no cause can be determined (idiopathic) References:[1][2] Epidemiology References:[1][3][4][5][6][7] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Epidemiologic approaches to the study of Parkinson's disease etiology. Epidemiology 1999; 10: 327-336. 13. Tanner CM, Aston DA. Epidemiology of Parkinson's disease and akinetic syndromes. Curr Opin Neurol 2000; 13: 427-430. 14. Calne DB. [ge-bu.nl]
Epidemiology : prevalence of MSA in four studies ranged from 1·9 to 4·9 cases per 100 000 people. similar to those of other well-known neurodegenerative disorders such as Huntington’s disease and motor neuron disease. no single environmental [slideshare.net]
Pathophysiology
Furthermore, they illustrate the metabolic effects related to acute focal lesions of the SN as opposed to the progressive degeneration in idiopathic PD and may serve to help unravel the complicated pathophysiology underlying these conditions. [ncbi.nlm.nih.gov]
Clinical expressions, postulated pathophysiological mechanisms and responsiveness to antiparkinson medication represent differences between IPD and secondary Parkinsonism (SP). OBJECTIVES: To evaluate NMS expressions in IPD, SP and a control group. [clinicaltrials.gov]
We discuss the pathophysiology leading to involvement of substantia nigra and treatment options. [content.iospress.com]
The pathophysiology is thought to be due to degeneration of a subgroup of midbrain (A8) neurons, as this area is spared in Parkinson patients not having the tremor. [medicaljoyworks.com]
PATHOPHYSIOLOGY 4/4/2018KIRSHA,9 10. 4/4/2018KIRSHA,10 11. Cardinal Features Motor Symptoms Autonomic Symptoms Mental Status Changes CLINICAL FEATURES 4/4/2018KIRSHA,11 12. CLINICAL EVALUATION 1. Clinical findings. 2. [slideshare.net]
Prevention
People taking medicines that can cause secondary parkinsonism should be carefully monitored by the provider to prevent the condition from developing. [health.firstlighthealthsystem.org]
People taking medicines that can cause secondary parkinsonism should be carefully monitored by the doctor to prevent the condition from developing. References Lang AE. Parkinsonism. In: Goldman L, Schafer AI. [irmcphysicians.com]
Treating underlying conditions, such as stroke or infections, can reduce symptoms or prevent the condition from getting worse. If symptoms make it hard to do everyday activities, the provider may recommend medicine. [stelizabeth.com]