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Semantic Dementia

Semantic Primary Progressive Aphasia


Presentation

  • In the first experimental condition, the pictures represented personally familiar persons present in a specific spatial and temporal context.[ncbi.nlm.nih.gov]
Collapse
  • A final step-change in the areas engaged and the quality of recollection then preceded the collapse of autobiographical memory.[ncbi.nlm.nih.gov]
Borborygmi
  • Somatic symptom disorder was associated with misidentification and preoccupation with normal bodily sensations such as hunger, bladder filling, borborygmi, rhinorrhea, and reflux; excessive concern over the incompletely understood meaning or source of[ncbi.nlm.nih.gov]
Suggestibility
  • The SD group had better face familiarity scores, suggesting a potentially useful clinical test for distinguishing SD from DP.[ncbi.nlm.nih.gov]
Compulsive Disorder
  • We describe a patient presenting with late-onset typical obsessive-compulsive disorder (OCD) that lasted for 10 years as an isolated condition before developing clinical and neuroimaging features of SD.[ncbi.nlm.nih.gov]
Claustrophobia
  • Here we describe the case of a 71-year-old patient with a typical clinicoanatomical syndrome of semantic dementia led by selective (predominantly right-sided) temporal lobe atrophy, who showed striking amelioration of previously disabling claustrophobia[ncbi.nlm.nih.gov]
Dysphasia
  • He had a global loss of conceptual knowledge in the context of a fluent dysphasia and intact syntax.[ncbi.nlm.nih.gov]
  • Medlars ProCite RefWorks Reference Manager 2019 Oxford University Press Close Navbar Search Filter Mobile Microsite Search Term Close search filter search input Abstract We report five patients with a stereotyped clinical syndrome characterized by fluent dysphasia[doi.org]

Workup

  • Wernicke-Korsakoff syndrome; profound retrograde and anterograde amnesia, and to fill in memory gaps, patients CONFABULATE Initial workup of dementia should include complete metabolic profile, including liver function tests and thyroid studies Young pt[quizlet.com]

Treatment

  • Whereas an abundance of research has been dedicated to treatment for anomia in individuals with focal brain damage due to stroke, considerably less work has been done regarding treatment for patients with progressive language decline.[ncbi.nlm.nih.gov]

Prognosis

  • Prognosis of Semantic Dementia The prognosis is poor. It progresses rapidly and become worse. The semantic dementia causes death in 2 to 10 years from infection and some time from general failure of body systems.[depression-guide.com]
  • Best prognosis tends to be in those with the semantic type, and survival may be as long as ten years or more. Worst prognosis is associated in the overlap syndrome with motor neurone disease, and there may only be 3-5 years between onset and death.[patient.info]
  • What is the prognosis (the outlook) for frontotemporal dementia? The outcome for people with frontotemporal dementia is poor.[medicinenet.com]
  • Further research should be directed at understanding and developing new diagnostic and therapeutic modalities to improve the patients' prognosis and quality of life.[doi.org]

Etiology

  • Improved reliability of diagnoses will be increasingly important as trials for etiology-specific treatments become available. We also discuss the implications of these syndromes for theories of language function.[ncbi.nlm.nih.gov]
  • When sporadic disease is not sporadic: The potential for genetic etiology. Archives of Neurology, 61 (2), 213–216. PubMed Google Scholar Goodglass, H., & Kaplan, E. F. (1983). The Boston diagnostic aphasia examination .[link.springer.com]
  • Grammar is also diminished, including reduced syntactic complexity13 and fewer subordinate clauses.14 Crucially, whether an individual becomes more impaired in either his or her grammar or word finding can be indicative of the location of the etiology[todaysgeriatricmedicine.com]
  • Cottier, Early-onset dementias: Specific etiologies and contribution of MRI, Diagnostic and Interventional Imaging, 95, 4, (377), (2014).[oadoi.org]

Epidemiology

  • Author information 1 Neuroscience and Aphasia Research Unit (NARU), University of Manchester, UK; Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), Department of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK[ncbi.nlm.nih.gov]
  • Among the many highlights of the Fifth Edition are: * An extensively updated chapter on the cellular and molecular biology of the neuron* An expanded chapter on the epidemiology and genetics of neuropsychiatric disorders* An extensively revised and expanded[books.google.de]
  • Ikeda M, Ishikawa T, Tanabe H: Epidemiology of frontotemporal lobar degeneration. Dement Geriatr Cogn Disord 2004;17:265–268. Gregory CA, Hodges JR: Frontotemporal dementia: use of consensus criteria and prevalence of psychiatric features.[karger.com]
  • Epidemiology and Treatment Because the lvPPA has been only recently described (Gorno-Tempini et al. 2004 ), there is still little known about its epidemiology and treatment.[doi.org]
  • Heritability, however, varies with the different clinical subtypes (discussed below). [ 4 ] Epidemiology [ 5 ] FTD is much less common than Alzheimer's disease and vascular dementia.[patient.info]
Sex distribution
Age distribution

Pathophysiology

  • BACKGROUND: Developmental prosopagnosia (DP) and semantic dementia (SD) may be the two most common neurologic disorders of face processing, but their main clinical and pathophysiologic differences have not been established.[ncbi.nlm.nih.gov]
  • […] earlier than AD, in 6th decade Pathophysiology of frontotemporal dementia abnormal tau proteins with neuronal loss and lgiosis; dense silver-staning intraneural inclusions called Pick bodies FTD with pick bodies present atrophy of frontal or temporal[quizlet.com]
  • […] capture pathophysiological changes become available.[bmj.com]

Prevention

  • Finally, we showed normal learning of phonological sequences for GE when he was prevented from repeating his errors.[ncbi.nlm.nih.gov]
  • Prevention of Semantic Dementia The prevention of the semantic dementia is unknown. Prognosis of Semantic Dementia The prognosis is poor. It progresses rapidly and become worse.[depression-guide.com]
  • No prevention. Available services National Aphasia Association 29 John St., Suite 1103 New York, NY 10038 www.aphasia.org[alzheimer-europe.org]
  • […] targeted toward Alzheimer's disease, frontotemporal dementia, depression, Parkinson's disease, or any other brain related disease, we can hope that much of the information discovered will translate across boundaries and become helpful in finding a way to prevent[healthcentral.com]

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