Presentation
There is a widely held belief that most patients presenting with senile chorea have late-onset Huntington's disease (HD) with an unknown family history. [ncbi.nlm.nih.gov]
Mestre Medicine Continuum 2016 The clinical approach to the diagnosis of adult patients presenting with chorea, using Huntington disease (HD) as a point of reference, is reviewed and the clinical elements that help in the diagnostic workup are presented [semanticscholar.org]
We measured CAG trinucleotide repeat expansion in the HD gene in four patients with a clinical presentation of senile chorea and found that CAG repetition lengths were normal. [neurology.org]
Gastrointestinal
- Overeating
Over 250 new illustrations More than 100 Contributors representing over 9 international countries 8 new chapters including Imaging, Fatigue, Aging Hand, Obesity, Complementary Therapies for the Aging Patient Latest information on evaluation and treatment [books.google.com]
[…] and New Zealand journal of medicine 1998 The majority of patients with 'senile' chorea actually have Huntington's disease even in the absence of a family history, according to a detailed prospective study of patients presenting with undiagnosed chorea over [semanticscholar.org]
METHODS: Detailed prospective study of patients presenting with undiagnosed chorea over a three year period to a Movement Disorder Clinic. RESULTS: Twelve patients, aged 50 to 89 years, were identified. [ncbi.nlm.nih.gov]
The specter of this cruel disease continues to hang over the entire Guthrie family. [streetdirectory.com]
Psychiatrical
- Claustrophobia
If the patient cannot tolerate MRI because of the presence of an implanted metallic object (such as a pacemaker) or severe claustrophobia, then spinal CT with intrathecal contrast may be performed. [geriatricscareonline.org]
Face, Head & Neck
- Facial Grimacing
The symptoms vary in severity--from mild cases in which there is restlessness, facial grimacing, and a slight degree of incoordination of movements, to severe cases involving involuntary movements that incapacitate the child. 1 Causes of Chorea Senile [streetdirectory.com]
Neurologic
- Chorea
Chronic Progressive Chorea Chronic Progressive Choreas Progressive Chorea, Chronic Progressive Choreas, Chronic Chorea, Rheumatic Choreas, Rheumatic Rheumatic Choreas Sydenham's Chorea Chorea, Sydenham's Sydenhams Chorea St. [ncbi.nlm.nih.gov]
Look at other dictionaries: Chorea minor — Klassifikation nach ICD 10 I02.0 Rheumatische Chorea mit Herzbeteiligung I02.9 Rheumatische Chorea ohne Herzbeteiligung … Deutsch Wikipedia chorea — choreal, choreic, choreatic /kawr ee at ik, kohr /, adj. choreoid [medicine.academic.ru]
- Involuntary Movements
Pathol. 1. any of several diseases of the nervous system characterized by jerky, involuntary movements, chiefly of the… … Universalium Chorea — Ceaseless rapid complex body movements that look well coordinated and purposeful but are, in fact, involuntary [medicine.academic.ru]
|Disorder presenting primarily with chorea (disorder)|Dubini chorea|Dubini's chorea|Dubini's chorea (disorder)|Dubini's disease|Electric chorea|Electric chorea (disorder)|Hemiballism|Hemiballism (abnormal involuntary movements)|Hemiballism (disorder)| [averbis.com]
Athetosis is a continuous stream of slow, flowing, writhing involuntary movements. It usually affects the hands and feet. Hemiballismus is a type of chorea, usually involving violent, involuntary flinging of one arm and/or one leg. [msdmanuals.com]
The remaining chapters focus on the abnormal involuntary movements associated with each disease or syndrome. [books.google.com]
Confirming the diagnosis TD presents as a polymorphous involuntary movement disorder, 5 - 8 most often with nonrhythmic, repetitive, purposeless hyperkinetic symptoms. [mdedge.com]
- Tremor
[…] include Wilson's Disease and severe essential tremor (ET is usually postural but when servere can be seen at rest or even with movement) Resting Tremor Postural Tremor Action Tremor Description Tremor when skeletal muscle is at rest. [stanfordmedicine25.stanford.edu]
Startle syndromes Section 9 Essential tremor 33. Essential tremor 34. Management of essential tremor, including medical and surgical approaches 35. Orthostatic tremor – a review Section 10 Dystonia 36. Early-onset primary dystonia 37. [elsevier.com]
TREMOR Tremor is a universal phenomenon. The description of tremors often relies on an assessment of the tremor frequency: this is hard to judge with the naked eye. [academic.sun.ac.za]
Tremor See also the separate Tremor article. This is a rhythmic movement of part of the body. Essential tremor and Parkinsonian tremor are the most common forms of tremo. [ 16 ]. [patient.info]
unspecified 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes chorea NOS ( G25.5 ) essential tremor ( G25.0 ) hysterical tremor ( F44.4 ) intention tremor ( G25.2 ) ICD-10-CM Diagnosis Code I02 Rheumatic chorea 2016 2017 2018 2019 Non-Billable [icd10data.com]
- Dysarthria
Motor symptoms: impairment related to involuntary (chorea) and voluntary movements, reduced manual dexterity, dysarthria, dysphagia, gait instability, and falls are common; parkinsonism and dystonia can be seen in patients with an earlier onset of disease [neupsykey.com]
For example, a family with spastic paraplegia, truncal ataxia, and dysarthria, but without other clinical features of DRPLA, has been found to show homozygosity for an allele that carries intermediate CAG repeats in the DRPLA gene ( Kuroharas et al., [clinicalgate.com]
In children, the disease is manifested initially by progressive dystonia, rigidity and dysarthria, and hepatic dysfunction, whereas in adults psychiatric symptoms, tremor, and dysarthria usually predominate Wilson's Disease continued Since Kayser-Fleischer [endoflifecare.tripod.com]
[…] incontinence ) Advanced stages Movement dysfunction Hypokinetic motor symptoms ( dystonia, rigidity, bradykinesia ) Akinetic mutism (inability to move or speak) Motor impersistence ; (inability to sustain simple voluntary acts, e.g., tongue protrusion ) Dysarthria [amboss.com]
Patients with ALS commonly present with gait disturbance, falls, foot drop, weakness in grip, dysphagia, or dysarthria. [geriatricscareonline.org]
- Action Tremor
[…] include Wilson's Disease and severe essential tremor (ET is usually postural but when servere can be seen at rest or even with movement) Resting Tremor Postural Tremor Action Tremor Description Tremor when skeletal muscle is at rest. [stanfordmedicine25.stanford.edu]
It is an action tremor occurring during activity and is of greater amplitude when reaching for a target. The tremor may involve the head, causing titubation (a side to side head tremor), and also often affects the voice. [academic.sun.ac.za]
Kinetic or action tremor - occurs during voluntary active movement of an upper body part. Intention tremor is one that occurs when a tremor worsens as a goal-directed hand movement nears its intended target. [patient.info]
Essential Tremor Essential tremor (ET) is the most common form of tremor. The tremor of ET is an action tremor, which is present when the limbs are in active use (eg, while writing or holding a cup). [geriatricscareonline.org]
Workup
Mestre Medicine Continuum 2016 The clinical approach to the diagnosis of adult patients presenting with chorea, using Huntington disease (HD) as a point of reference, is reviewed and the clinical elements that help in the diagnostic workup are presented [semanticscholar.org]
ADLs Inability to Initiate Meaningful Activities Anxiety Spatial Disorientation Rejection of Care Food Refusal Insomnia Apathy and Agitation Elopement and Interference with Others References Introduction Epidemiology Challenges in Geriatric Psychiatry WorkUp [books.google.com]
Treatment
Schrag Medicine Journal of Neurology 1998 The symptomatic treatment of chorea is unsatisfactory and, at least in HD, neuropsychiatric disturbance may be much more important for the family, and potential disease-modifying treatments are now being explored [semanticscholar.org]
Form Treatment Huntington's-related A common treatment is dopaminergic antagonists, although treatment is largely supportive. Tetrabenazine is the only FDA approved drug for the treatment of Huntington's disease-related chorea. [en.wikipedia.org]
Physical Therapy Surgery References Introduction Effects of Ageing and Related Diseases on Endocrine Diseases The Hormonal Fountain of Youth References Introduction Water Homeostasis in the Elderly Workup and Treatment of Hyponatraemia Workup and Treatment [books.google.com]
Symptoms And Treatment Of Overdose: Symptoms Signs and symptoms of overdosage may include drowsiness, sweating, hypotension and hypothermia. Treatment: Treatment is symptomatic. [rxmed.com]
Prognosis
Prognosis The prognosis of chorea depends on its cause. Huntington's chorea is incurable, leading to the patient's death 10 – 25 years after the first symptoms appear. [encyclopedia.com]
What is the prognosis of chorea? The outlook of chorea depends on its cause. Syndenham chorea can be resolved using antibiotics. On average, patients will recover within 1 to 6 months. [medic8.com]
References: [4] [17] Prognosis [amboss.com]
Conclusion References Introduction Geriatric Characteristics Adverse Drug Reactions and Drug Misuse General Rules for Individual Prescription Tools for Collective Evaluation References Introduction Pharmacology Illicit Drug Misuse Aetiology Detection Prognosis [books.google.com]
Etiology
[…] options Subheadings: analysis anatomy and histology blood cerebrospinal fluid chemically induced classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology [ncbi.nlm.nih.gov]
Here, we report a typical case of ‘senile chorea’ associated with PAPS, thus expanding the potential underlying etiologies and further narrowing the window of primary ‘senile chorea’. [jns-journal.com]
Although the most common etiologies are vascular and metabolic disorders, neuroacanthocytosis, Wilson and Huntington diseases are included in the differential diagnosis. [tjn.org.tr]
Here, we report a typical case of ’senile chorea’ associated with PAPS, thus expanding the potential underlying etiologies and further narrowing the window of primary ’senile chorea’. [kns.cnki.net]
Chorea gravidarum Hyperthyroidism Birth control pills Hyperosmolar nonketotic hyperglycemic encephalopathy Vascular Hemichorea/hemiballismus with subthalamic nucleus lesion Post-pump choreoathetosis after cardiac surgery Periarteritis nodosa Unknown etiology [neupsykey.com]
Epidemiology
PubMed search builder options Subheadings: analysis anatomy and histology blood cerebrospinal fluid chemically induced classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology [ncbi.nlm.nih.gov]
Homes Successful Ageing Future Research Introduction Developments in the UK 20052010 Services Patients Views and Involvement Additional Responsibilities for Geriatric Psychiatry Services Other Issues An International Perspective References Introduction Epidemiology [books.google.com]
Epidemiology Sex : ♂ = ♀ Peak incidence : ∼ 40 years of age HD is one of the most common hereditary diseases of the brain. References: [1] [2] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Epidemiology of tardive dyskinesia before and during the era of modern antipsychotic drugs 44. Unusual focal dyskinesias Section 12 Tics 45. Stereotypic movement disorders 46. Tourette syndrome and other tic disorders Section 13 Other syndromes 47. [elsevier.com]
Epidemiology of multiple scle-rosis in northwestern Sardinia: further evidence for higher frequency in Sar-dinians compared to other Italians. Neuroepidemiology 1996;15:10-9.16. Bufill E, Blesa R, Galan I, Dean G. [docslide.net]
Pathophysiology
Deep brain field potential recordings and functional imaging using single photon emission tomography enabled us to suggest pathophysiological mechanisms for the symptoms. [ncbi.nlm.nih.gov]
[…] of the Ageing Bladder Special Disease States Pharmacology as it Relates to the Ageing Bladder Surgical Disease of the Ageing Bladder Conclusion References Introduction Benign Prostatic Hyperplasia Prostate Cancer Prostatitis References Introduction Pathophysiology [books.google.com]
The exact pathophysiology of HCHB is unknown, but focal microhemorrhage, ischemic injury, hyperglycemia, hyperviscosity, and mineralization have been suggested in radiological and pathological studies. 7 Most cases were associated with hyperglycemia and [e-jmd.org]
References: [3] Pathophysiology Summary : Molecular and cellular changes lead to neuronal loss and gliosis in the striatum (particularly in the caudate nucleus ) and, subsequently, the thalamus and the cortex Involvement of direct cytotoxic effects Disturbance [amboss.com]
Conclusion Chorea can be due to a multitude of disorders with a wide variety of pathophysiologies. [movementdisorders.org]
Prevention
[…] imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology genetics history immunology metabolism microbiology mortality nursing organization and administration parasitology pathology physiology physiopathology prevention [ncbi.nlm.nih.gov]
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.de]
Prevention Because there is no “gold standard” treatment for TD, it is important to minimize the risk of TD by taking preventive measures and detecting incipient signs of the disorder. [mdedge.com]