Edit concept Question Editor Create issue ticket

Senile Osteoporosis

Osteoporoses Senile


Presentation

  • There was no evidence to suggest adrenal involution, or ;adrenopause', in any of the cases, and no changes were present to suggest that the osteoporosis was the result of terminal excess of ;anti-anabolic' steroids.[ncbi.nlm.nih.gov]
  • Case contributed by Dr Kewal Arunkumar Mistry Diagnosis almost certain Diagnosis almost certain Presentation Kyphotic deformity, backache.[radiopaedia.org]
  • At present the world practice has a great experience of hormone replacement therapy (HRT) based on administration of estrogens.[osteomed.su]
  • Presents from family and friends, cake and candles, and a flood of great memories highlight the day. But your 70 th birthday is also a BIG WARNING about a condition called “senile osteoporosis.”[algaecal.com]
  • Best Iines fitted to these data and attenuation in all directions were presented. Results of this study indicate that ultrasonic velocity and modulus of elastioity increase with increasing frequency.[aott.org.tr]
Back Pain
  • Signs of Senile Osteoporosis Low back pain is common, and may radiate from the back outwardly. Back pain is worse when standing, especially for prolonged periods, and is usually relieved by lying down.[osteoporosis.newlifeoutlook.com]
  • “Epidural injections for the diagnosis and treatment of low-back pain.” Spine 5.1 (1980): 78-86. Leave a reply[beammed.com]
  • Back pain due to vertebral fracture is a common expression of this disorder, yet surprisingly little information is available regarding the incidence of vertebral atrophy in older persons.[annals.org]
  • A lumbosacral film was taken of all patients, who were then divided into two groups: patients with no back pain were graded as 0, 1 by Seville's index (normal group); and those who had frequent and longstanding back pain were graded as 2,3,4 by Seville's[healio.com]
  • At such moments, the patient may feel back pain that is worse when walking or standing. In the case of compression fracture of multiple vertebrae simultaneously possible curvature of the spine, inducing muscle spasm and pain.[back.vsebolezni.com]
Bone Pain
  • Pathological Fractures Osteoporosis has no symptoms until a fracture occurs, which causes bone pain, height loss, and abnormal spine curvature.[fortherecordmag.com]
  • Pathological Fractures Multiple Wedge Fractures Osteoporosis has no symptoms until a fracture occurs, which causes bone pain, height loss, and abnormal spine curvature.[osteoporosisprotocols.com]
  • Endocrine abnormality, age, idiopathic, inactivity, alcohol, calcium deficiency Vit D deficiency or abnormal vit D pathway, hypophosphatemia, hypophosphatasia, renal tubular acidosis Symptoms and signs Pain and tenderness at fracture site Generalized bone[orthobullets.com]
  • This loss of bone strength may be asymptomatic for many years, although significant loss may be accompanied by fractures and bone pain.[rad.washington.edu]
  • Osteomalacia/ Rickets: Osteomalacia is softening of the bones due to a Vitamin D deficiency in adults, which can result in decalcification of the bone, fractures, skeletal deformities, bone pain and muscle weakness.[physio-pedia.com]
Low Back Pain
  • Signs of Senile Osteoporosis Low back pain is common, and may radiate from the back outwardly. Back pain is worse when standing, especially for prolonged periods, and is usually relieved by lying down.[osteoporosis.newlifeoutlook.com]
  • “Epidural injections for the diagnosis and treatment of low-back pain.” Spine 5.1 (1980): 78-86. Leave a reply[beammed.com]
  • Clinical studies on the conservative treatment of low back pain. New Medical Journal. 1976; 19:310-316. 2. Jahng JS, Kang KS, Kim MK. Osteoporosis and fracture of the proximal femur. New Medical Journal. 1987; 30:67-72. 3.[healio.com]
Decrease in Height
  • Clinical Signs and Symptoms [7] Back pain: Episodic, acute low thoracic/high lumbar pain Compression fracture of the spine Bone fractures Decrease in height Kyphosis Dowager’s hump Decreased activity tolerance Early satiety Associated Co-morbidities As[physio-pedia.com]
  • […] in height of 2-3 cm after each vertebral compression fracture and progressive kyphosis Patients with hip fractures may demonstrate the following: Limited ROM with end-range pain on a FABER (flexion in abduction and external rotation) hip joint test Decreased[emedicine.medscape.com]
Paravertebral Muscle Spasm
  • muscle spasms exacerbated by activity and decreased by lying supine Patients often remain motionless in bed because of fear of causing an exacerbation of pain Acute pain usually resolves after 4-6 weeks; in the setting of multiple fractures with severe[emedicine.medscape.com]
Decreased Libido
  • Decreased testosterone in regularly menstruating women with decreased libido: a clinical observation // J Sex Marital Ther. 2001. Vol.27. P.513–519. Braunstein G.D., Sundwall D.A., et al.[osteomed.su]
Sexual Dysfunction
  • Serum androgen levels in healthy premenopausal women with and without sexual dysfunction: Part A. Serum androgen levels in women aged 20–49 years with no complaints of sexual dysfunction // J Impot Res. 2004. Vol.16. P.112–120.[osteomed.su]

Workup

  • A medical workup to diagnose osteoporosis will include a complete medical history, x rays, and urine and blood tests. The doctor may also order a BMD (bone mineral density) test.[news-medical.net]
  • Screening at-risk populations is essential (see Workup).[emedicine.medscape.com]
Magnesium Increased
  • Urinary excretion of calcium and magnesium increased significantly. The findings indicate that treatment with 1alpha-hydroxycholecalciferol may be useful in osteoporosis due to aging or following corticosteroid administration.[ncbi.nlm.nih.gov]

Treatment

  • They displayed a columnar T-score -3.5 and femoral T-score -2.5, had been under antireabsorptive treatment since at least 12 months.[ncbi.nlm.nih.gov]

Prognosis

  • The prognosis for osteoporosis is not deadly, but it does have its challenges. Increase in the likelihood of fractures, especially of the hip, present the greatest obstacle.[interactive-biology.com]
  • […] less than resorption resulting in a net bone loss increased osteoclast activity is significant in areas of bone with large surface area such as the vertebral bodies, leading to vertebral compression fractures there is trabecular and cortical bone loss Prognosis[medbullets.com]
  • This lower fracture risk was independent of BMD and other risk factors. [69] Prognosis The prognosis for osteoporosis is good if bone loss is detected in the early phases and proper intervention is undertaken.[emedicine.medscape.com]
  • Non-weight-bearing, high force exercise were shown to have moderate effects at the femoral neck. [21] (level of evidence 1a) Clinical Considerations Metabolic bone diseases results in impaired healing rates, therefore should be considered when determining prognosis[physio-pedia.com]

Etiology

  • The etiologic factors that lead to senile osteoporosis still are unclear. Based on the available experimental and clinical evidence, we update our earlier proposal that zinc deficiency plays a role in the pathogenesis of senile osteoporosis.[ncbi.nlm.nih.gov]
  • Urinary 17-ketosteroid and 17-hydroxysteroid levels had been determined for a large number of women with symptomatic vertebral osteoporosis, but the data could not be interpreted for possible etiologic significance without FULL TEXT[annals.org]
  • After a complete evaluation, an attributable etiology of the fall was determined.[doi.org]
  • Most of the etiologic considerations regarding senile osteoporosis are not very clear for physicians yet.[en.wikipedia.org]
  • Atik OS, Uslu MM, Eksioglu F, Satana T (2006) Etiology of senile osteoporosis: A hypothesis. Clin Orthop Relat Res 443: 25-27. Roubenoff R (2003) Catabolism of aging: Is it an inflammatory process? Curr Opin Clin Nutr Medtab Care 6: 295-299.[omicsonline.org]

Epidemiology

  • […] are inseparably superimposed. ” In this volume, Duque and Kiel have gathered an international panel of experts to highlight the unique features of senile osteoporosis and cons- eration of this disease spans the very basic through the clinical and the epidemiologic[books.google.de]
  • Kiel -- Fracture epidemiology among individuals 75 / Heike A. Bischoff-Ferrari -- Falls as a geriatric syndrome: how to prevent them? how to treat them? / Manuel Montero-Odasso -- Non-pharmacological treatments for falls and fractures / Stephen R.[worldcat.org]
  • Definition Epidemiology Sex: ( 4:1 ) Age of onset: 50–70 years Demographics : higher incidence in individuals of Asian, Hispanic and northern European ancestry than in black populations References: [1] Epidemiological data refers to the US, unless otherwise[amboss.com]
  • Introduction Clinical definition decreased bone mass (osteopenia) that significantly increases the patient's risk of fracture Epidemiology incidence most common types of osteoporosis are post-menopausal senile risk factors post-menopausal women being[medbullets.com]
  • View Article PubMed Google Scholar Masud T, Morris RO: Epidemiology of falls. Age Ageing. 2001, 30: 3-7. 10.1093/ageing/30.3.255.[doi.org]
Sex distribution
Age distribution

Pathophysiology

  • Abstract Little is known about the pathophysiology of normal human and mouse senescence. On the other hand, the pathology of age-related disorders, such as senile osteoporosis, has been investigated.[ncbi.nlm.nih.gov]
  • Ng, The Pathophysiology of the Aging Skeleton, Current Osteoporosis Reports, 10.1007/s11914-010-0035-y, 8, 4, (235-240), (2010).[doi.org]
  • Senile osteoporosis, formerly known as osteoporosis type II, has been recently recognized as a geriatric syndrome with a particular pathophysiology.[en.wikipedia.org]
  • […] mass and microarchitectural deterioration of bone tissue leading to enhanced bone fragility and a consequent increase in fracture risk,” it is not clear that osteoporosis represents a single disease as much as a similar response of bone to different pathophysiologies[books.google.de]

Prevention

  • These findings suggest that administration of 1 alpha (OH)D3 is effective in preventing the occurrence of pathological fractures in senile osteoporosis.[ncbi.nlm.nih.gov]
  • "Prevention and treatment of senile osteoporosis and hip fractures". Minerva Medica. 100 (1): 79–94. PMID 19277006. Duque G, Huang DC, Macoritto M, et al. (March 2009).[en.wikipedia.org]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!