Presentation
There was no evidence to suggest adrenal involution, or ;adrenopause', in any of the cases, and no changes were present to suggest that the osteoporosis was the result of terminal excess of ;anti-anabolic' steroids. [ncbi.nlm.nih.gov]
Case contributed by Dr Kewal Arunkumar Mistry ◉ Diagnosis almost certain Diagnosis almost certain Presentation Kyphotic deformity, backache. [radiopaedia.org]
Close and Catherine Sherrington -- Medical treatment of age-related osteoporosis: present and future / Steven Boonen -- Treatment of osteoporosis in long-term care / Gustavo Duque and Louise Mallet -- Fracture care in the elderly / Christopher M. [worldcat.org]
Overview Snapshot A 67-year-old woman presents to the emergency department after falling while walking down the stairs of her home. She landed on her rear on a carpeted floor and denies hitting her head. [medbullets.com]
Presents from family and friends, cake and candles, and a flood of great memories highlight the day. But your 70 th birthday is also a BIG WARNING about a condition called “senile osteoporosis.” [algaecal.com]
Entire Body System
- Pain
At such moments, the patient may feel back pain that is worse when walking or standing. In the case of compression fracture of multiple vertebrae simultaneously possible curvature of the spine, inducing muscle spasm and pain. [back.vsebolezni.com]
Symptoms of senile osteoporosis include pain in the lower back, radiating through the back outwardly and in the standing position, back pain becomes adverse, extenuating through a lying down position. With this issue, mid-back fractures also arise. [beammed.com]
Signs of Senile Osteoporosis Low back pain is common, and may radiate from the back outwardly. Back pain is worse when standing, especially for prolonged periods, and is usually relieved by lying down. [osteoporosis.newlifeoutlook.com]
Other regions that may be thought to be related to the pain may also be treated. Acupuncture may improve some symptoms such as inflammation, pain, and reduced mobility. It may promote the release of endorphins that regulate pain in the body. [paindoctor.com]
- Underweight
Underweight/inactive: Bone remodeling occurs in response to physical stress, so physical inactivity can lead to significant bone loss. [biachiro.biz]
Respiratoric
- Cough
Malnutrition, malabsorption Low body weight References:[1][2][3][4][5] Clinical features Mostly asymptomatic Pathological fractures: spontaneous fracture following mild physical exertion or minor trauma (e.g., lifting something, bending over, or sneezing/coughing [amboss.com]
Symptoms of severe osteoporosis can include a fracture from a fall or even from a strong sneeze or cough. They can also include back or neck pain, or loss of height. Back or neck pain or loss of height can be caused by a compression fracture. [healthline.com]
[…] tool is not as widely used as the FRAX but is another validated fracture prediction tool that does account for falls, and may be a better tool for use in men. [87] Complications Vertebral compression fractures often occur with minimal stress, such as coughing [emedicine.medscape.com]
Cardiovascular
- Hypotension
Two patients were diagnosed with vasovagal syncope, two with postural hypotension, one with postprandial hypotension and one with carotid sinus hypersensitivity. [doi.org]
Musculoskeletal
- Osteoporosis
Osteoporosis was estimated by standard radiological morphometric and densitometric techniques, in the metacarpals and thoraco-lumbar vertebrae. [ncbi.nlm.nih.gov]
Clinical Orthopaedics 63 (1969), 196–209 Geographical variations in senile osteoporosis. [edwardbetts.com]
- Fracture
fractures of the spine, femoral neck fractures, distal radius fractures, and fractures of the proximal end of the humerus--to examine secular change. [ncbi.nlm.nih.gov]
- Back Pain
Signs of Senile Osteoporosis Low back pain is common, and may radiate from the back outwardly. Back pain is worse when standing, especially for prolonged periods, and is usually relieved by lying down. [osteoporosis.newlifeoutlook.com]
Symptoms of senile osteoporosis include pain in the lower back, radiating through the back outwardly and in the standing position, back pain becomes adverse, extenuating through a lying down position. With this issue, mid-back fractures also arise. [beammed.com]
Back pain due to vertebral fracture is a common expression of this disorder, yet surprisingly little information is available regarding the incidence of vertebral atrophy in older persons. [annals.org]
A lumbosacral film was taken of all patients, who were then divided into two groups: patients with no back pain were graded as 0, 1 by Seville's index (normal group); and those who had frequent and longstanding back pain were graded as 2,3,4 by Seville's [healio.com]
At such moments, the patient may feel back pain that is worse when walking or standing. In the case of compression fracture of multiple vertebrae simultaneously possible curvature of the spine, inducing muscle spasm and pain. [back.vsebolezni.com]
- Bone Pain
Pathological Fractures Osteoporosis has no symptoms until a fracture occurs, which causes bone pain, height loss, and abnormal spine curvature. [fortherecordmag.com]
Pathological Fractures Multiple Wedge Fractures Osteoporosis has no symptoms until a fracture occurs, which causes bone pain, height loss, and abnormal spine curvature. [osteoporosisprotocols.com]
D pathway, hypophosphatemia, hypophosphatasia, renal tubular acidosis Symptoms and signs Pain and tenderness at fracture site Generalized bone pain and tenderness Xray Axial fracture predominance Appendicular fracture predominance, symmetric, includes [orthobullets.com]
This loss of bone strength may be asymptomatic for many years, although significant loss may be accompanied by fractures and bone pain. [rad.washington.edu]
joint, or muscle pain. [physio-pedia.com]
- Bone Disorder
Metabolic Bone Disorders Child VGHTC 201505 Osteoporotic Vertebral Fracture & Non-fracture Deformity BP III - Nutritional, metabolic, endocrine MEDS2144 Spinal and Pelvic Trauma Mod8 review MSK- Dr Ferreiro Metabolic Bone Disorders Nutritional Metabolic [radiopaedia.org]
Differential Laboratory Abnormalities in Select Bone Disorders Etiology Serum Phosphate Serum Calcium Serum Alkaline Phosphatase Parathyroid Hormone Osteomalacia / rickets Decreased Decreased Increased Increased Osteoporosis Normal Normal Normal Normal [medbullets.com]
Osteoporosis (os-te-o-po-RO-sis) is a disorder in which there is loss of bone density, which increases the likelihood of fracture. [humanillnesses.com]
Young-Eun Park, David S Musson, Dorit Naot and Jillian Cornish, Cell–cell communication in bone development and whole-body homeostasis and pharmacological avenues for bone disorders, Current Opinion in Pharmacology, 10.1016/j.coph.2017.04.001, 34, (21 [doi.org]
Neurologic
- Irritability
During this whole procedure, the pain might be sharp, or it might be long-lasting and irritating (White, 1980). [beammed.com]
Side effects of the oral tablets may include nausea, difficulty swallowing, heartburn, irritation of the esophagus, and gastric ulcer. [physio-pedia.com]
Workup
A medical workup to diagnose osteoporosis will include a complete medical history, x rays, and urine and blood tests. The doctor may also order a BMD (bone mineral density) test. [news-medical.net]
Screening at-risk populations is essential (see Workup). [emedicine.medscape.com]
Treatment
They displayed a columnar T-score>-3.5 and femoral T-score>-2.5, had been under antireabsorptive treatment since at least 12 months. [ncbi.nlm.nih.gov]
The osteometry, performed before treatment detected bone cavities (Fig. 2, 4, 6 – before treatment). After 10 months of treatment with «Osteomed forte» cavities have closed (Fig. 3, 5, 7). [osteomed.su]
Prognosis
The prognosis for osteoporosis is not deadly, but it does have its challenges. Increase in the likelihood of fractures, especially of the hip, present the greatest obstacle. [interactive-biology.com]
[…] less than resorption resulting in a net bone loss increased osteoclast activity is significant in areas of bone with large surface area such as the vertebral bodies, leading to vertebral compression fractures there is trabecular and cortical bone loss Prognosis [medbullets.com]
This lower fracture risk was independent of BMD and other risk factors. [69] Prognosis The prognosis for osteoporosis is good if bone loss is detected in the early phases and proper intervention is undertaken. [emedicine.medscape.com]
Non-weight-bearing, high force exercise were shown to have moderate effects at the femoral neck. [21] (level of evidence 1a) Clinical Considerations Metabolic bone diseases results in impaired healing rates, therefore should be considered when determining prognosis [physio-pedia.com]
Etiology
The etiologic factors that lead to senile osteoporosis still are unclear. Based on the available experimental and clinical evidence, we update our earlier proposal that zinc deficiency plays a role in the pathogenesis of senile osteoporosis. [ncbi.nlm.nih.gov]
After a complete evaluation, an attributable etiology of the fall was determined. [doi.org]
Urinary 17-ketosteroid and 17-hydroxysteroid levels had been determined for a large number of women with symptomatic vertebral osteoporosis, but the data could not be interpreted for possible etiologic significance without FULL TEXT [annals.org]
English: BL blood CF cerebrospinal fluid CI chemically induced CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]
Etiology Primary osteoporosis (most common form) Type I (postmenopausal osteoporosis): postmenopausal women Estrogen stimulates osteoblasts and inhibits osteoclasts. [amboss.com]
Epidemiology
[…] are inseparably superimposed. ” In this volume, Duque and Kiel have gathered an international panel of experts to highlight the unique features of senile osteoporosis and cons- eration of this disease spans the very basic through the clinical and the epidemiologic [books.google.de]
Definition Epidemiology Sex: ♀ > ♂ (∼ 4:1) Age of onset: 50–70 years Demographics: higher incidence in individuals of Asian, Hispanic and northern European ancestry than in black populations References:[1] Epidemiological data refers to the US, unless [amboss.com]
Kiel -- Fracture epidemiology among individuals 75+ / Heike A. Bischoff-Ferrari -- Falls as a geriatric syndrome: how to prevent them? how to treat them? / Manuel Montero-Odasso -- Non-pharmacological treatments for falls and fractures / Stephen R. [worldcat.org]
1987-89 Allowable Qualifiers English: BL blood CF cerebrospinal fluid CI chemically induced CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]
Introduction Clinical definition decreased bone mass (osteopenia) that significantly increases the patient's risk of fracture Epidemiology incidence most common types of osteoporosis are post-menopausal senile risk factors post-menopausal women being [medbullets.com]
Pathophysiology
This study reviews new evidence on the pathophysiology of senile osteoporosis, with emphasis upon the mechanism of action of current osteoporosis treatments. [ncbi.nlm.nih.gov]
[…] awareness that osteo porosis is a treatable and partly preventable disease of the elderly, and not just the inevitable consequence of ageing, comes at a time of rapid progress in measurement of bone mass and in a better understanding of the physiology and pathophysiology [books.google.com]
[…] mass and microarchitectural deterioration of bone tissue leading to enhanced bone fragility and a consequent increase in fracture risk,” it is not clear that osteoporosis represents a single disease as much as a similar response of bone to different pathophysiologies [books.google.de]
Ng, The Pathophysiology of the Aging Skeleton, Current Osteoporosis Reports, 10.1007/s11914-010-0035-y, 8, 4, (235-240), (2010). [doi.org]
Prevention
In addition, strategies to prevent or reduce falls are integral to comprehensive osteoporosis management. Vitamin D combined with calcium has a role in primary prevention. [ncbi.nlm.nih.gov]
Among these agents, oral bisphosphonates have been the first choice for the treatment and prevention of osteoporotic fractures. [doi.org]
talk to your doctor about the best way to prevent it. [healthline.com]