Presentation
Experience from this case suggests that cryptococcal infection should be considered in the differential diagnosis of pregnant women presenting with vague systemic symptoms such as fever, abdominal pain, and generalized lymphadenopathy. [ncbi.nlm.nih.gov]
The most common etiologic agents in septic abortion are those present in the normal flora of the female genital tract. The majority of septic abortions are polymicrobial infections, with participation of both aerobic and anaerobic bacteria. [popline.org]
Entire Body System
- Fever
Fever resolution time Sangines 1969 reported fever resolution time as a measure of effectiveness. [doi.org]
"Response to treatment was evaluated by the patient's 'fever index' expressed in degree-hour and defined as the total quantity of fever under the daily temperature curve with 99°F (37.2°C) as the baseline".There was no difference in duration of hospitalisation [ncbi.nlm.nih.gov]
"Response to treatment was evaluated by the patient's 'fever index' expressed in degree-hour and defined as the total quantity of fever under the daily temperature curve with 99°F (37.2°C) as the baseline". [cochrane.org]
- Pain
Perforation of the uterus during the abortion typically causes severe abdominal pain. Septic shock may result, causing hypothermia, hypotension, oliguria, and respiratory distress. [msdmanuals.com]
A 27-year-old woman at 10 weeks' gestation developed abdominal pain, fever, leukocytosis, peritoneal signs, closed cervix and a viable pregnancy. Progression from acute salpingitis to septic abortion was documented. [ncbi.nlm.nih.gov]
Lower abdominal pain for 11 days Fever for 1 day 3. [slideshare.net]
- Chills
Soluble fibrin monomer complexes (SFMC) were determined in patients with septic abortion (body temperatures of more than 39 degree C and/or chills without apparent signs of endotoxic shock), with infected abortion, with non-infected abortion and with [ncbi.nlm.nih.gov]
Symptoms and Signs Symptoms and signs of septic abortion typically appear within 24 to 48 h after abortion and are similar to those of pelvic inflammatory disease (eg, chills, fever, vaginal discharge, often peritonitis) and often those of threatened [msdmanuals.com]
Self-induced abortion using non-sterile methods Presence of a sexually transmitted infection such as chlamydia As a complication of pregnancy with an intrauterine device (IUD) A septic abortion is likely if a pregnant woman develops a fever with chills [fertilitysmarts.com]
Clinical features: – pyrexia : associated with the chills and rigors suggest blood stream spread of infection. [infofru.com]
In a woman with septic abortion, signs and symptoms that are related to the infection are mainly: High fever, usually above 101 °F / 38 °C Chills Severe abdominal pain and/or cramping /or strong perineal pressure Beginning miscarriage symptoms (heavy [en.wikipedia.org]
- Infertility
Kidney failure, fatal bleeding, and formation of scar tissue in the intestinal and pelvic organs leading to intestinal blockage and infertility are some of the potential consequences of untreated septic abortion. [fertilitysmarts.com]
In severe cases, there is a risk of future infertility for the patient. [wisegeek.com]
[…] cancer endometriosis endometrium estrogen evaluation examination factors fetal fetus fibroid fistula fluid gestational age glucose Gynecology Maulana Azad hemorrhage heparin Hospital New Delhi hypertension hysterectomy hysteroscopy increased infection infertility [books.google.com]
Intestinal organs may also become infected, potentially causing scar tissue with chronic pain, intestinal blockage, and infertility. If the septic abortion is not treated quickly and effectively, the woman may die. [en.wikipedia.org]
Infertility 6. Respiratory failure 7. Cardiac arrest How to Test for Septic Abortion 1. Blood Test Firstly, a check on your white blood count, organ functions and oxygen level in your blood will be tested. 2. [beautyglitch.com]
- Rigor
Septicemia was defined by a positive blood culture rigors. Hypotension was assumed to be due to hemorrhage unless endotoxic shock was positively identified. Significant hemorrhage was also diagnosed if a blood transfusion was required. [ncbi.nlm.nih.gov]
Clinical features: – pyrexia : associated with the chills and rigors suggest blood stream spread of infection. [infofru.com]
• Fever for 1day with no chills and rigor, max temp not recorded. • No h/o burning micturition, and increased frequency • No h/o SOB, palpitation, headache, dizziness and LOC. 4. Obs history: she is P2 A1 L2, 1St child : Fe, 18 yr. [slideshare.net]
Respiratoric
- Tachypnea
SIRS is characterized by fever >38°C, tachycardia >90 bpm, tachypnea RR >20, white blood cell count >12,000 or 10% immature forms. Septic shock includes SIRS plus a suspected or present infection. [glowm.com]
Gastrointestinal
- Abdominal Pain
Perforation of the uterus during the abortion typically causes severe abdominal pain. Septic shock may result, causing hypothermia, hypotension, oliguria, and respiratory distress. [msdmanuals.com]
A 27-year-old woman at 10 weeks' gestation developed abdominal pain, fever, leukocytosis, peritoneal signs, closed cervix and a viable pregnancy. Progression from acute salpingitis to septic abortion was documented. [ncbi.nlm.nih.gov]
Cardiovascular
- Tachycardia
All study subjects satisfied the following diagnostic criteria: pyrexia of equal to or greater than 38 C, tachycardia equal to or greater than 90/min, foul smelling vaginal discharge, uterine tenderness, adnexal tenderness, peritonitis, or features of [ncbi.nlm.nih.gov]
Tachycardia of more than 100 per min. 24. [slideshare.net]
SIRS is characterized by fever >38°C, tachycardia >90 bpm, tachypnea RR >20, white blood cell count >12,000 or 10% immature forms. Septic shock includes SIRS plus a suspected or present infection. [glowm.com]
Fetus
- First Trimester Bleeding
Epidemiology Prevalence : First Trimester Bleeding in 25% of pregnant women III. [fpnotebook.com]
First-trimester bleeding in a pregnant woman has an extensive differential diagnosis ( Table 2 ) and should be evaluated with a full history and physical examination. [aafp.org]
Urogenital
- Pelvic Pain
Signs of this complication include a high fever, pelvic pain, and a foul-smelling vaginal discharge, as well as nausea and vomiting. If the woman is not treated, septicemia can develop as the infection spreads. [wisegeek.com]
History Quantity and rate of blood loss Bleeding similar or worse than Menstrual Bleeding is associated with Early Pregnancy Loss Pelvic Pain or cramping Exclude Ectopic Pregnancy ! [fpnotebook.com]
Floor Kari Bo 05 Feb 2015 Hardback 50,98 € 62,50 € Save 11,52 € Add to basket 25% off Chronic Pelvic Pain William Ledger 12 Jan 2015 Paperback 31,43 € 41,99 € Save 10,56 € Add to basket Chronic Pelvic Pain Paolo Vercellini 19 Apr 2011 Paperback 85,89 [bookdepository.com]
pain, chronic pelvic inflammatory disease, infertility, etc. [doi.org]
[…] abdominal pain and tenderness. [infofru.com]
- Oliguria
On the other hand, reductions in both clearances were present in most patients who had a long period of oliguria (GFR: 84.9 +/- 4.2 and RPF: 418.1 +/- 33.1). [ncbi.nlm.nih.gov]
The woman should have intravenous fluids to maintain blood pressure and urine output (Oliguria or hypouresis both names from roots meaning "not enough urine" is the low output of urine). [en.wikipedia.org]
Septic shock may result, causing hypothermia, hypotension, oliguria, and respiratory distress. [msdmanuals.com]
Blood transfusion: early and adequate blood transfusion is not only helpful to improve the body resistance and anaemia but is also affective to prevent or minimize shock and oliguria. [infofru.com]
Abortions induced by untrained birth attendants or dais, lady health visitors; or paramedics in dark rooms end up in sepsis, perforation of the uterus, peritonitis and acute renal failure (oliguria/anuria). [ispub.com]
- Foul Smelling Vaginal Discharge
All study subjects satisfied the following diagnostic criteria: pyrexia of equal to or greater than 38 C, tachycardia equal to or greater than 90/min, foul smelling vaginal discharge, uterine tenderness, adnexal tenderness, peritonitis, or features of [ncbi.nlm.nih.gov]
Signs of this complication include a high fever, pelvic pain, and a foul-smelling vaginal discharge, as well as nausea and vomiting. If the woman is not treated, septicemia can develop as the infection spreads. [wisegeek.com]
[…] bleeding Foul-smelling vaginal discharge Backache or heavy back pressureA cold or urinary tract infection may mimic many of the symptoms. [en.wikipedia.org]
- Uterine Tenderness
All study subjects satisfied the following diagnostic criteria: pyrexia of equal to or greater than 38 C, tachycardia equal to or greater than 90/min, foul smelling vaginal discharge, uterine tenderness, adnexal tenderness, peritonitis, or features of [ncbi.nlm.nih.gov]
Symptoms and signs of abortion‐related infections include fever, pelvic/abdominal pain, prolonged vaginal bleeding, uterine tenderness, foul‐smelling uterine discharge, and elevated inflammatory markers, findings similar to those associated with pelvic [doi.org]
Workup
Administer broad-spectrum antibiotics before completing diagnostic workup. [13] Failure to obtain information about recent termination of pregnancy may lead to a wrong diagnosis or delayed/inappropriate treatment. [emedicine.medscape.com]
Microbiology
- Staphylococcus Aureus
Isolated organisms include bacteria such as anaerobic Peptostreptococcus, antibiotic‐resistant and toxin‐producing Staphylococcus aureus, strains of Clostridia species such as Clostridium perfringens, Group A Streptococcus, and Escherichia coli ( Eschenbach [doi.org]
Treatment
The most critical treatment of septic abortion remains the prompt removal of infected tissue. Antibiotic administration and fluid resuscitation provide necessary secondary levels of treatment. [doi.org]
It appears that cefoxitin was successful as a single agent in the treatment of septic abortion. [ncbi.nlm.nih.gov]
Antibiotic treatment is very important for the treatment of septic abortion. The recommended treatments include antibiotics that have effects on different types of bacteria. [cochrane.org]
Prognosis
This study is to evaluate, once again, the clinical management and prognosis of septic abortion, and to determine if present concepts of therapy are valid.The diagnosis of septic abortion is difficult to make with certainty. [nejm.org]
Record: found Abstract: found Article: not found Clostridium bacteremia: emphasis on the poor prognosis in cirrhotic patients. Bacteremic episodes caused by anaerobes are unusual and the clinical importance of Clostridium bacteremia remains unclear. [scienceopen.com]
Etiology
The most common etiologic agents in septic abortion are those present in the normal flora of the female genital tract. The majority of septic abortions are polymicrobial infections, with participation of both aerobic and anaerobic bacteria. [popline.org]
Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
The most common etiological organisms were Clostridium perfringens (77%), Clostridium bifermentans (9%), and Clostridium septicum (4%). Only one patient with C. septicum bacteremia had a histocytotoxic infection, which was a fatal gas gangrene. [scienceopen.com]
Etiology and Risk Factors Chromosomal abnormalities are a direct cause of spontaneous abortion. One meta-analysis 9 found that a chromosomal abnormality occurs in 49 percent of spontaneous abortions. [aafp.org]
Epidemiology
Epidemiology Prevalence : First Trimester Bleeding in 25% of pregnant women III. [fpnotebook.com]
EPIDEMIOLOGY • Septic abortion remains a primary cause of maternal mortality in the developing world, mostly as a result of illegal abortions • 21.6 million women experience an unsafe abortion worldwide each year; 18.5 million of these occur in developing [slideshare.net]
Epidemiology Frequency United States Frequency of complications depends on gestational age (GA) at the time of miscarriage or abortion and method of abortion (see the Gestational Age from Estimated Date of Delivery calculator). [emedicine.medscape.com]
Pathophysiology
Thus, updated knowledge of the pathophysiology, clinical presentation, microbes, and proper treatment is needed to optimally treat this emergency condition when it exists. [doi.org]
Pathophysiology Postabortion complications develop as a result of 3 major mechanisms as follows: incomplete evacuation of the uterus and uterine atony, which leads to hemorrhagic complications; infection; and injury due to instruments used during the [emedicine.medscape.com]
Prevention
Unpublished data from Bangladesh Association for Prevention of Septic Abortion (BAPSA), Dhaka, Bangladesh, 2012. Bangladesh Association for the Prevention of Septic Abortion (BAPSA), M. [freethesaurus.com]
Septic abortion provides a paradigm for preventive medicine, with opportunities for primary, secondary, and tertiary prevention 2 .Scope of the ProblemA 1973 report described an adolescent admitted to a large Boston teaching hospital with what proved [nejm.org]
Prevention Always keep in mind that prevention is better than cure! Therefore, here are a few ways to avoid Septic abortions. 1. Avoid Unintended Pregnancy It’s as simple as this! Use whatever means necessary to do so. [beautyglitch.com]
Septic abortion is a paradigm of preventive medicine, relating to all levels of prevention – primary, secondary, and tertiary. 2 In the past, obstetricians/gynecologists were often the experts in management of sepsis. [glowm.com]
Septic abortion is mostly a preventable condition, and there are ample opportunities for primary, secondary and tertiary prevention. [ispub.com]