In most cases these agents are present in overdose or there is a synergism of two or more drugs. The diagnosis is complicated in mild forms and fatal cases. [infona.pl]

• Fever

  But too much serotonin causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures). Severe serotonin syndrome can cause death if not treated. [mayoclinic.org]

  Last Update: 2012-04-10 Usage Frequency: 2 Quality: Finnish · oirekokonaisuus (tunnetaan nimellä serotoniinioireyhtymä), johon liittyy kuumeilu ilman selvää English · a combination of symptoms (know as serotonin syndrome) including unexplained fever with [mymemory.translated.net]

• Shivering

  But too much serotonin causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures). Severe serotonin syndrome can cause death if not treated. [mayoclinic.org]

• Nausea

  John's wort, ginseng and nutmeg Over-the-counter cough and cold medications containing dextromethorphan (Delsym) Anti-nausea medications such as granisetron (Sancuso, Sustol), metoclopramide (Reglan), droperidol (Inapsine) and ondansetron (Zofran) Linezolid [mayoclinic.org]

• Diarrhea

  But too much serotonin causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures). Severe serotonin syndrome can cause death if not treated. [mayoclinic.org]

• Hypertension

  Management of severe arterial hypertension associated with serotonin syndrome: a case report analysis based on systematic review techniques. Ther Adv Psychopharmacol. 2019;9:2045125318818814. - PMC - PubMed Publication types [pubmed.ncbi.nlm.nih.gov]

• Agitation

  The diagnosis can be made in patients with a history of exposure to a serotonergic drug plus one or more of the following: spontaneous clonus, inducible clonus with agitation and diaphoresis, ocular clonus with agitation and diaphoresis, tremor and hyperreflexia [pubmed.ncbi.nlm.nih.gov]

  Signs and symptoms include: Agitation or restlessness Insomnia Confusion Rapid heart rate and high blood pressure Dilated pupils Loss of muscle coordination or twitching muscles High blood pressure Muscle rigidity Heavy sweating Diarrhea Headache Shivering [mayoclinic.org]

• Tremor

  The diagnosis can be made in patients with a history of exposure to a serotonergic drug plus one or more of the following: spontaneous clonus, inducible clonus with agitation and diaphoresis, ocular clonus with agitation and diaphoresis, tremor and hyperreflexia [pubmed.ncbi.nlm.nih.gov]

  Signs include: High fever Tremor Seizures Irregular heartbeat Unconsciousness When to see a doctor If you suspect you might have serotonin syndrome after starting a new drug or increasing the dose of a drug you're already taking, call your health care [mayoclinic.org]

• Altered Mental Status

  Symptoms can range from mild to fatal and classically include altered mental status, autonomic dysfunction, and neuromuscular excitation. [pubmed.ncbi.nlm.nih.gov]

• Seizure

  But too much serotonin causes signs and symptoms that can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever and seizures). Severe serotonin syndrome can cause death if not treated. [mayoclinic.org]

• Hyperreflexia

  The diagnosis can be made in patients with a history of exposure to a serotonergic drug plus one or more of the following: spontaneous clonus, inducible clonus with agitation and diaphoresis, ocular clonus with agitation and diaphoresis, tremor and hyperreflexia [pubmed.ncbi.nlm.nih.gov]

PMID: 12925718 Serotonin toxicity: a practical approach to diagnosis and treatment. Isbister GK, Buckley NA, Whyte IM. Isbister GK, et al. Med J Aust. 2007 Sep 17;187(6):361-5. doi: 10.5694/j.1326-5377.2007.tb01282.x. Med J Aust. 2007. [pubmed.ncbi.nlm.nih.gov]

(Print) 978-951-656-512-8 Publication status Published - 2018 MoE publication type D2 Article in professional manuals or guides or professional information systems or text book material Acute Disease +therapy Emergencies Emergency Medicine Emergency Treatment [researchportal.helsinki.fi]

This article gives an overview on the pathophysiological mechanisms, the causes and treatment of serotonin toxicity. Identifiers Authors User assignment Assign yourself or invite other person as author. It allow to create list of users contirbution. [infona.pl]

If you have severe or rapidly worsening symptoms, seek emergency treatment immediately. [mayoclinic.org]

• serotonin syndrome: • serotonin syndrome, a potentially life-threatening condition (see the section “ possible side effects”), may occur with venlafaxine treatment, particularly when taken with other medicines. [mymemory.translated.net]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

This article gives an overview on the pathophysiological mechanisms, the causes and treatment of serotonin toxicity. Identifiers Authors User assignment Assign yourself or invite other person as author. It allow to create list of users contirbution. [infona.pl]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team [pubmed.ncbi.nlm.nih.gov]

Etiology Epidemiology Pathophysiology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare Team Outcomes Review Questions References Similar articles Prevention [pubmed.ncbi.nlm.nih.gov]

Prevention Taking more than one serotonin-related medication or increasing your dose of a serotonin-related medication increases your risk of serotonin syndrome. [mayoclinic.org]