Presentation
In the literature, S marcescens infections of the lower extremity have presented as granulomatous ulceration, abscess, bullous cellulitis, and necrotizing fasciitis. [ncbi.nlm.nih.gov]
Entire Body System
- Sepsis
Serratia marcescens is an unusual cause of sepsis and neurological spread is especially ominous. To report the case of a 34-week neonate who developed this rare condition and to discuss diagnostic and therapeutic measures. [ncbi.nlm.nih.gov]
Serratia marcescens is an emerging cause of preterm sepsis but its epidemiology is still largely unknown. [aricjournal.biomedcentral.com]
Cerebral abscesses are extremely rare in neonates and usually arise in the setting of sepsis in patients with several other morbid conditions. [scielo.br]
- Weakness
Microbiol. 54: 1896-1898 Lighthart B., Sewall D. & Thomas D.R. 1988: Effect of several stress factors on the predatory mite, Metaseiulus occidentalis (Acari: Phytoseiidae), to the weak bacterial pathogen Serratia marcescens. J. Invert. [eje.cz]
Etymology: L. part. adj. marcescens, becoming weak, fading away. Approved Lists reference: SKERMAN (V.B.D.), McGOWAN (V.) and SNEATH (P.H.A.) (editors): Approved Lists of Bacterial Names. Int. J. Syst. [bacterio.net]
Broad-spectrum cephalosporins such as cefotaxime, ceftazidime, ceftriaxone and cefepime are weak inducers of the enzyme and thus remain stable against AmpC-inducible bacteria (50). [antimicrobe.org]
- Collapse
A generalized transducing bacteriophage forSerratia marcescens View Options Get Access View options PDF View PDF Media Media Other Tables Go to Go to Show all references Request permissions Expand All Collapse Expand Table Authors Info & Affiliations [cdnsciencepub.com]
However, some symptomatic or asymptomatic immature plants may collapse suddenly in the middle of the season or just after fruit set. Typically, all the leaves turn yellow within a few days, starting about a week or two before harvest. [web.archive.org]
Interestingly, SEM did not reveal any decomposition, disruption, or collapse of conidia, conidiophore, hypha, or mycelium on challenging the endophytic fungi with endophytic S. marcescens MSRBB2. [nature.com]
- Fatigue
In this article, we report an 85-year-old woman with diabetes mellitus who presented with low-grade fever and general fatigue. She was administered intravenous prednisolone under a diagnosis of right Bell's palsy before this admission. [ncbi.nlm.nih.gov]
(%) of patients* Constitutional Fever 28 (73.7%) Cough 3 (7.9%) Night sweats 1 (2.6%) Fatigue 6 (15.8%) Chest discomfort/pain 3 (7.9%) Murmur 8 (21.1%) Arrhythmia 3 (7.9%) Confusion 3 (7.9%) Splenomegaly 5 (13.2%) GI (diarrhea and abdominal pain) 5 [cureus.com]
Respiratoric
- Pneumonia
RESULTS: Pneumonia was caused by Gram-negative bacteria in 115 patients during the study period from January 1, 2004, to August 12, 2014. [ncbi.nlm.nih.gov]
It is also a rare cause of endocarditis and osteomyelitis (particularly in people who use intravenous drugs recreationally), pneumonia, and meningitis. [globalrph.com]
- Sputum
Till now, it had not been reported from clinical samples such as sputum, urine etc. in Rajasthan. [ijmm.org]
Interestingly, her sputum and bronchial washing samples grew S. marcescens. The computed tomography-guided lung biopsy demonstrated necrotic granulomatous changes. [ncbi.nlm.nih.gov]
Skin
- Erythema
Erythema with multiple abscesses on the left ankle and leg at presentation (A), day 1 following surgical debridement of infected tissues (B), and 2 months later with complete healing following a skin graft (C). Figure 2. [mdedge.com]
CASE REPORT An 81-year-old man with progressive renal failure and multiple medical problems presented with erythema, warmth, and swelling of his right lower extremity. [journals.lww.com]
Neurologic
- Meningism
Infectious Diseases physician was consulted, lumbar puncture was performed and purulent meningitis was confirmed. [ncbi.nlm.nih.gov]
- Headache
Previously healthy individual, admitted to Orthopaedic Department for routine arthroscopy, approximately within 24 hours after operation was performed complained of headache and fever. [ncbi.nlm.nih.gov]
Churg-Strauss syndrome, multiple myeloma, or combined variable immune deficiency) Symptoms at time of initial positive Serratia marcescens included: nasal discharge (55%), nasal congestion/obstruction (34%), headache/facial pressure (34%), decreased sense [alliedacademies.org]
Workup
[…] fasciitis of the lower extremity; both organisms had identical antibiograms. 15 The portal of entry in another case was an infected intravenous catheter with bacteremia leading to the development of cellulitis at a distant site. 7 Despite an extensive workup [journals.lww.com]
Initial workup revealed an embolus in the right popliteal artery as well as lesions consistent with infarction in the spleen and bilateral kidneys on abdominal CT scan. [cureus.com]
Microbiology
- Legionella Pneumophila
The Lly protein protects Legionella pneumophila from light but does not directly influence its intracellular survival in Hartmannella vermiformis 19. [cdnsciencepub.com]
While pathogens like Shigella flexneri and Listeria monocytogenes are able to evade autophagy recognition [14], [15], it was shown that others, like Brucella abortus, Coxiella burnetii or Legionella pneumophila, can replicate in autophagosome-like compartments [journals.plos.org]
Treatment
Clinically, all patients treated with empirical first-generation cephalosporin showed treatment resistance, and oral quinolone monotherapy was the most preferred antibiotic regimen without treatment failure, with an average treatment duration of 25 days [ncbi.nlm.nih.gov]
Prognosis
BACKGROUND: It is known that infections with Serratia marcescens can take a progressive course in preterm infants and that meningoencephalitis with this pathogen exhibits an extremely bad neurologic prognosis. [ncbi.nlm.nih.gov]
Based on these and several other reports of S. marcescens outbreaks, meningitis alone can be recognized as an indicator of poor prognosis. [scielo.br]
DISCUSSION The prognosis for vision in metastatic endophthalmitis is guarded.3 In cases with involvement of the posterior segment where the vitreal inflammatory reaction prevents fundus visualization, the outcome is generally very poor.6,7 Regardless [healio.com]
Etiology
Abstract We report a case of postsurgical wound infection of polymicrobial etiology caused by Serratia marcescens and Pseudomonas aeruginosa following the use of a radial forearm free flap for oncological tongue reconstruction. [ncbi.nlm.nih.gov]
The etiology of this phenomenon remains unknown, and there is no evidence that gram-negative rods such as S. marcescens have an increased ability to increase to the matrix ligands that are associated with sterile vegetation but are important in the etiology [cureus.com]
Epidemiology
KEYWORDS: Serratia; beta-lactamases; infection control; molecular epidemiology [ncbi.nlm.nih.gov]
There have been many reports concerning the identification, antibiotic susceptibility, pathogenicity, epidemiological investigations and typing of this organism. Accurate identification is important in defining outbreaks. [doi.org]
J Clin Microbiol 1978;8:46.Google Scholar 28.Grimont, PAD, Grimont, F, Proteinase zymograms of Serratia marcescens as an epidemiological tool. [cambridge.org]
the journal of the Society for Healthcare Epidemiology of America. [shea-online.org]
Pathophysiology
We discuss the pathophysiology of the lesions and the impact of the various imaging methods. [ncbi.nlm.nih.gov]
[…] opportunistic pathogen in humans. [10] Derivatives of prodigiosin have recently been found to have immunosuppressive properties and antitumor activity in vivo [11, 12] and are also currently being considered as a candidate treatment for Chagas disease. [13] Pathophysiology [emedicine.medscape.com]
Prevention
An investigation was conducted to identify potential sources of contamination and prevent further infections. METHODS: Cases were defined as S. marcescens BSIs in patients receiving PN from the pharmacy between January and March 2011. [ncbi.nlm.nih.gov]
The overall case fatality rate for the entire epidemic period was 16.6% (23% in NICU) and the death rate of infection in S. marcescens exposed population was 2% (3% in NICU).Preventive measures The first preventive measures adopted to prevent cross-transmission [elsevier.es]
Residency Program, Brigham and Women's Hospital/Massachusetts General Hospital, Boston, MA Financial support: Internal support from Centers for Disease Control and Prevention, Atlanta, GA. [journals.lww.com]