Presentation
Hypotension was present in only 51%. Although DIC was present in 85% of patients, hypofibrinogenemia was documented in only 26%. [docslide.net]
Clinical presentation is variable - 50% of patients developing meningitis only - 10% developing septicemia only - 40% developing both Symptoms: usually febrile, ill-appearing, lethargy, vomiting, and nuchal rigidity Septicemia leads to capillary leak, [brainscape.com]
Clinical presentation: Acute lobar pneumonia. [slideplayer.com]
Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. [allbooksy.com]
The age, presenting complaints, bleeding manifestations, clinical details and other investigations were noted. [ajts.org]
Entire Body System
- Splenectomy
Response to splenectomy was more in young patients and in those patients who had higher immediate post-splenectomy thrombocytosis. [ajts.org]
In such cases, splenectomy may improve the response to transfusion. [medtextfree.wordpress.com]
Splenectomy for hemocytopenia in systemic lupus erythematosus. A controlled appraisal. Arch Intern Med 1979, 139, 773–776. PubMed Google Scholar 22. Allison, A.C., Denman, A.M., Barnes, R.D. [link.springer.com]
Rev 2010;23:740 ) In children, splenectomy is avoided in favor of splenic repair, partial splenectomy or splenic autotransplant Must consider possibility of accessory spleen(s) if splenectomy is performed for hematologic disorders Laboratory ======== [pathologyoutlines.com]
In general, survival beyond 1 yr of life occurs in 40 yrs after splenectomy. [ziladoc.com]
- Asymptomatic
(patients or asymptomatic carriers). Transmission: droplets inhalation. Pathogenesis and microbial virulence: Colonization of the nasopharynx then spread to the bronchi and alveoli. Polysaccharide capsule resist phagocytosis. [slideplayer.com]
- gram-negative diplococcus Neisseria meningitidis - transmission is person-to-person via respiratory droplets, often from an asymptomatic carrier - Up to 30% of teenagers and 10% of adults carry meningococci in the upper respiratory tract. [brainscape.com]
General ========================================================================= 75% of nonparasitic splenic cysts Usually due to trauma; some may be epithelial cysts with denuded epithelial lining Usually solitary, asymptomatic Wall composed of dense [pathologyoutlines.com]
In a few cases splenectomy has alleviated some of the problems of portal hypertension.21 CLINICAL FEATURES A slight to moderate enlargement of the spleen is usually asymptomatic and is first found during a routine examination of the abdomen. [medtextfree.wordpress.com]
646.5 bacteriuria, asymptomatic 646.5 bariatric surgery status 649.2 bicornis or bicornuate uterus 654.0 biliary problems 646.8 bone and joint disorders (conditions classifiable to 720-724 or conditions affecting lower limbs classifiable to 711-719, [theodora.com]
- Congestive Heart Failure
General ========================================================================= Caused by portal hypertension, which may be due to Budd-Chiari syndrome (thrombosis of hepatic veins), cirrhosis, congestive heart failure, portal vein stenosis, thrombosis [pathologyoutlines.com]
- Malnutrition
[…] salt (and water) depletion 992.4 water depletion 992.3 nervous 300.5 newborn 779.89 senile 797 Protanomaly 368.51 Protanopia (anomalous trichromat) (complete) (incomplete) 368.51 Protection (against) (from) - see Prophylactic Protein deficiency 260 malnutrition [theodora.com]
Respiratoric
- Pneumonia
Case report DOI: 10.1016/j.adengl.2012.05.027 Purpura Fulminans Associated with Streptococcus pneumoniae Septicemia in an Asplenic Pediatric Patient Púrpura fulminante en relación con septicemia por Streptococcus pneumoniae en un paciente pediátrico asplénico [actasdermo.org]
pneumonia Viral pneumonia Animal, or Environmental Exposure. [slideplayer.com]
CLINICAL SIGNIFICANCE OF BACTEREMIA IN PNEUMOCOCCIC PNEUMONIA 10.1001/archinte.1937.00170200044004 This paper is concerned with an analysis of 1,586 cases of pneumonia associated with specific pneumococci of types I to XXXII (Cooper 1 ) in which cultures [scinapse.io]
In addition, it significantly decreases pneumonia and also prevent acute otitis media. [analesdepediatria.org]
However, some experts consider two doses of PCV7 or PCV13 sufficient to prevent invasive Streptococcus pneumoniae infection. [documents.mx]
Cardiovascular
- Heart Disease
642.2 heart and chronic kidney disease 642.2 heart and renal disease 642.2 heart disease 642.2 renal disease 642.2 hyperthyroidism 648.1 hypothyroidism 648.1 hysteralgia 646.8 icterus gravis 646.7 incarceration, uterus 654.3 incompetent cervix (os) 654.5 [theodora.com]
Musculoskeletal
- Myalgia
United States Most common symptoms are: - high fever (> 102° F) - Headache - rash petechial rash typically begins on the wrists and ankles but may be found anywhere, including the oral mucosa, as in this child spotless RMSF occurs in 10%-15% of cases - myalgias [brainscape.com]
These symptoms may include fever, malaise, myalgias, headache, vomiting, diarr hea, and abdominal p ain. The presence of g astrointestinal symptoms should never pr event the attending physician from entertaining a possible diagnosis of OPSI [2 ]. [ziladoc.com]
Neurologic
- Somnolence
Perineum, perineal - see condition Perineuritis NEC 729.2 Periodic - see also condition disease (familial) 277.31 edema 995.1 hereditary 277.6 fever 277.31 limb movement disorder 327.51 paralysis (familial) 359.3 peritonitis 277.31 polyserositis 277.31 somnolence [theodora.com]
Workup
Microbiology
- Streptococcus Pneumoniae
Case report DOI: 10.1016/j.adengl.2012.05.027 Purpura Fulminans Associated with Streptococcus pneumoniae Septicemia in an Asplenic Pediatric Patient Púrpura fulminante en relación con septicemia por Streptococcus pneumoniae en un paciente pediátrico asplénico [actasdermo.org]
Immunization of toddlers attending day care centers (DCCs) reduce transmission of Streptococcus pneumoniae (Pnc) and antibiotic resistant Streptococcus pneumoniae (R-Pnc) to theiryoung siblings. [analesdepediatria.org]
Nosocomial acquired. 5 Community-acquired acute pneumonia: Person-to-Person: A- Classic bacterial pneumonia: Streptococcus pneumoniae. Haemophilus influenzae. Klebsiella pneumoniae. Moraxella catarrhalis. [slideplayer.com]
However, some experts consider two doses of PCV7 or PCV13 sufficient to prevent invasive Streptococcus pneumoniae infection. [documents.mx]
Al- coolisme et pneumococcie grave, a propos dun cas de purpura fulminans a streptococcus pneumoniae. Rev Med Intern 1993; 14: 46-8. 27. Ohnishi M, Skimizu Y, Iwata K, Ookochi Y, Ooe K. [docslide.net]
Treatment
is 5%-10% If suspected, antibiotic treatment should be initiated without waiting for confirmatory culture testing ** Important note: Pneumococcus can have a very similar presentation to Meningococcemia One of the most contagious infectious diseases, [brainscape.com]
Culture follow-up Urine cultures • Patients with a positive urine culture require treatment tailored to the identified organism and their clinical status. [documents.mx]
Sardjito Yogyakarta 2014 Venous and arterial thrombosis More information Sepsis: Identification and Treatment Sepsis: Identification and Treatment Daniel Z. [docplayer.net]
There is currently no proof that such early self-treatment will lower the incidence of OPSI [1 ]. [ziladoc.com]
This reference stands as a convenient and time-saving reference for clinicians on the diagnosis, treatment, a ما يقوله الناس - كتابة مراجعة لم نعثر على أي مراجعات في الأماكن المعتادة. [books.google.com]
Prognosis
Alveolar hemorrhage incryoglobulinemia e an indicator of poor prognosis. Clin ExpRheumatol 2005;23:616e20.5. Manganelli P, Fietta P, Carotti M, Pesci A, Salaffi F. Respiratorysystem involvement in systemic vasculitides. [docslide.us]
The purpose of this study is to correlate the incidence of bacteremia and the death rate with the more common factors known or supposed to influence the prognosis, including (1) the type of pneumococcus, (2) the age of the patient, (3) the sex, (4) the [scinapse.io]
(See "Acute management, imaging, and prognosis of urinary tract infections in infants and children older than one month", section on 'Overview'.) [documents.mx]
ERSLEV Hypersplenism History and Definition Etiology and Pathogenesis Clinical Features Laboratory Features Therapy, Course, and Prognosis Hyposplenism Definition Etiology and Pathogenesis Clinical Features Laboratory Features Therapy, Course, and Prognosis [medtextfree.wordpress.com]
[…] hairline and coalesces into patches and plaques that spread cephalocaudally to the trunk and extremities --- this lasts for a week before fading to hyperpigmented patches which desquamate Treatment: - Vitamin A deficiency has been associated with a worse prognosis [brainscape.com]
Etiology
The vast majority of young children with fever have an infectious etiology. [documents.mx]
Under the best of circumstances the diagnosis may be easily made, although the exact etiology may be difficult to prove. [scinapse.io]
The striking predilection for the peripapillary retina suggests a local etiologic factor and distinguishes AIBSE from the multiple evanescent white dot syndrome. [ncbi.nlm.nih.gov]
They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]
Mc Coig Etiology and treatment of community-acquired pneumonia in ambulatory children. Pediatr Infect Dis J, 18 (1999), pp. 98-104 [45.] T. Heiskanen-Kosma, M. Korppi, C. Jokinen, S. Kurki, L. Heiskanen, H. [analesdepediatria.org]
Epidemiology
Greater knowledge of the epidemiology of pneumococcal disease and the efficiency of this vaccine in Spain will determine whether it should be included in the immunization schedule. [analesdepediatria.org]
"Blood Pressure" [SH] (epidemiology AND humans) [SH] SI Secondary Source ID The SI field identifies secondary source databanks and accession numbers, e.g., GenBank, GEO, PubChem, ClinicalTrials.gov, ISRCTN. [biomedsearch.com]
Outline Lymphatic System Defense Systems Innate Immune System Adaptive Defense System Immunodeficiencies Immune Responses Lymphatic System: Overview Figure 21.1a, b Lymphatic More information Infective Endocarditis: Infective Endocarditis: definition and epidemiology [docplayer.net]
Patterns of illness in the highly febrile young child: epidemiologic, clinical, and laboratory correlates. Pediatrics 1981; 67:694. 13. Leventhal JM. Clinical predictors of pneumonia as a guide to ordering chest roentgenograms. [documents.mx]
[…] tissue Discontinuous: no connection between spleen and ectopic splenic mass 20% of continuous types associated with other congenital defects, including peromelus (fetus with malformed limbs) and micrognathia; also testicular ectopia, inguinal hernia Epidemiology [pathologyoutlines.com]
Pathophysiology
Pochedly C, Sills RH, Schwartz A (eds): Disorders of the Spleen: Pathophysiology and Management. Marcel Dekker, New York, 1989. 27. [medtextfree.wordpress.com]
Data Extraction: The Extraction: The literature was reviewed to s ummarize the etiology and pathophysiology of postsplenectomy sepsis. [ziladoc.com]
Advertisement General ========================================================================= Largest lymphoid tissue of human body, accounting for 25% of total lymphocytes Lies between fundus of stomach and diaphragm Normally 150g with thin capsule Pathophysiology [pathologyoutlines.com]
Prevention
Alcohol is the third leading cause of preventable mortality and is associated with an estimated 100,000 deaths per year. The annual economic cost of alcohol use in 1990 was $100 billion in the United States, and greater tha... more [scinapse.io]
It has proven efficacy in the prevention of invasive disease caused by the seven vaccine serotypes. In addition, it significantly decreases pneumonia and also prevent acute otitis media. [analesdepediatria.org]
PREVENTIVE STRATEGIES Preventive strategies fall into three major categories: education, immunoprophylaxis, and chemoprophylaxis [5 ] [7] [8 ] ( Table 3 ). Education. Patient education represents a mandatory strategy in attempting t o prevent OPSI. [ziladoc.com]
It would have been hard to foresee, from the guinea-pig experiments, how little antitoxin is necessary in order effectively to prevent the natural infection with diphtheria in human beings. [jimmunol.org]
However, some experts consider two doses of PCV7 or PCV13 sufficient to prevent invasive Streptococcus pneumoniae infection. [documents.mx]