Presentation
Hypotension was present in only 51%. Although DIC was present in 85% of patients, hypofibrinogenemia was documented in only 26%. [docslide.net]
Clinical presentation is variable - 50% of patients developing meningitis only - 10% developing septicemia only - 40% developing both Symptoms: usually febrile, ill-appearing, lethargy, vomiting, and nuchal rigidity Septicemia leads to capillary leak, [brainscape.com]
Clinical presentation: Acute lobar pneumonia. [slideplayer.com]
Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. [allbooksy.com]
The age, presenting complaints, bleeding manifestations, clinical details and other investigations were noted. [ajts.org]
Entire Body System
- Amyloidosis
[…] have symp-toms similar to those caused by various airway disorders.Tracheobronchial amyloidosis is not typically associatedwith systemic amyloidosis or pulmonary parenchymalinvolvement.3 The inflammatory process involving thealveolar capillary walls [docslide.us]
Gertz MA, Kyle RA: Hepatic amyloidosis (primary [AL], immunoglobulin light chain): the natural history in 80 patients. Am J Med 85:73, 1988. 62. [medtextfree.wordpress.com]
The artery gives origin to abnormal colateral neo$ormed circulation (arrowheads) with tortuous arreries indicating excessive flow in an area of oval-shaped tumor tissue. osteoarthritis, chondrocalcinosis, amyloidosis, sickle cell disease, rheumatoid arthritis [vdocuments.mx]
General ========================================================================= Due to blunt trauma or abdominal surgery, causing hemoperitoneum and emergency splenectomy Only rarely ruptures spontaneously (associated with acute splenitis, amyloidosis [pathologyoutlines.com]
[…] drug - see Table of Drugs and Chemicals lack of vitamin NEC 269.2 [357.4] lead 357.7 organophosphate compounds 357.7 pellagra 265.2 [357.4] porphyria 277.1 [357.4] serum 357.6 toxic agent NEC 357.7 hereditary 356.0 idiopathic 356.9 progressive 356.4 in amyloidosis [theodora.com]
- Malaise
CASE REPORT A 46-year-old previously healthy white male presented to his local hospital approximately 18 h after the sudden onset of fever, chills, and malaise. 17 years earlier he had undergone a splenectomy following a gunshot wound. [docslide.net]
These symptoms may include fever, malaise, myalgias, headache, vomiting, diarr hea, and abdominal p ain. The presence of g astrointestinal symptoms should never pr event the attending physician from entertaining a possible diagnosis of OPSI [2 ]. [ziladoc.com]
- Congestive Heart Failure
General ========================================================================= Caused by portal hypertension, which may be due to Budd-Chiari syndrome (thrombosis of hepatic veins), cirrhosis, congestive heart failure, portal vein stenosis, thrombosis [pathologyoutlines.com]
Respiratoric
- Cough
Cough reflex*. Mucociliary escalator. Alveolar macrophage & antimicrobial. compounds: lysozyme, lactoferrin, complement and IgA. [slideplayer.com]
Hemoptysis occurred randomly ina day and accrued by coughing. She did not describe anyfever, loss of weight or perspiration at night. [docslide.us]
[…] leading causes of death in young children worldwide, with an estimated 197,000 deaths yearly Clinical Presentation: - After exposure, the incubation period lasts for 7-14 days - Then prodrome of high fevers, often > 104° F, with the classic triad of cough [brainscape.com]
(see also Whooping cough) 033.9 [484.3] infective, acquired prenatally 770.0 influenzal (broncho) (lobar) (virus) 487.0 inhalation (see also Pneumonia, aspiration) 507.0 fumes or vapors (chemical) 506.0 interstitial 516.8 with influenzal 487.0 acute [theodora.com]
Gastrointestinal
- Regurgitation
484.5] apex, apical - see Pneumonia, lobar ascaris 127.0 [484.8] aspiration 507.0 due to aspiration of microorganisms bacterial 482.9 specified type NEC 482.89 specified organism NEC 483.8 bacterial NEC 482.89 viral 480.9 specified type NEC 480.8 food (regurgitated [theodora.com]
Cardiovascular
- Thrombosis
Sardjito Yogyakarta 2014 Venous and arterial thrombosis More information Sepsis: Identification and Treatment Sepsis: Identification and Treatment Daniel Z. [docplayer.net]
Skin biopsy of one of the petechial lesions on his trunk revealed dermal thrombosis and hemorrhage, as typically seen in purpura fulminans. [docslide.net]
[…] of splenic veins, other thrombosis Portal vein thrombosis may be due to inflammation, inflammatory induced extrinsic pressure, trauma, tumor or idiopathic Portal vein stenosis may be due to extension of obliterative process at birth in umbilical vein [pathologyoutlines.com]
(venous) - see Thrombosis, puerperal thyroid dysfunction (conditions classifiable to 240-246) 648.1 toxemia (see also Toxemia, of pregnancy) 642.4 eclamptic 642.6 with pre-existing hypertension 642.7 pre-eclamptic (mild) 642.4 with convulsions 642.6 [theodora.com]
- Heart Disease
642.2 heart and chronic kidney disease 642.2 heart and renal disease 642.2 heart disease 642.2 renal disease 642.2 hyperthyroidism 648.1 hypothyroidism 648.1 hysteralgia 646.8 icterus gravis 646.7 incarceration, uterus 654.3 incompetent cervix (os) 654.5 [theodora.com]
Ears
- Otalgia
[…] diaphragm 786.52 due to (presence of) any device, implant, or graft classifiable to 996.0-996.5 - see Complications, due to (presence of) any device, implant, or graft classified to 996.0-996.5 NEC malignancy (primary) (secondary) 338.3 ear (see also Otalgia [theodora.com]
Musculoskeletal
- Myalgia
United States Most common symptoms are: - high fever (> 102° F) - Headache - rash petechial rash typically begins on the wrists and ankles but may be found anywhere, including the oral mucosa, as in this child spotless RMSF occurs in 10%-15% of cases - myalgias [brainscape.com]
These symptoms may include fever, malaise, myalgias, headache, vomiting, diarr hea, and abdominal p ain. The presence of g astrointestinal symptoms should never pr event the attending physician from entertaining a possible diagnosis of OPSI [2 ]. [ziladoc.com]
Neurologic
- Irritability
- Subacute sclerosing panencephalitis is a late, long-term complication caused by persistent infection ALL the most common malignancy of childhood Clinical Presentation: - Often presents with nonspecific symptoms of anorexia, irritability and lethargy [brainscape.com]
Hyperthermia or hypothermia Lethargy or irritability Poor feeding or vomiting Apnea, Dyspnea Jaundice Hypotension Diarrhea or abdominal distension Bulging fontanelle Seizures Bleeding manifestations, DIC 26 Case study 2 month old infant fever 5 days Febrile [powershow.com]
- Tremor
[…] condition Parinaud's conjunctivitis 372.02 oculoglandular syndrome 372.02 ophthalmoplegia 378.81 syndrome (paralysis of conjugate upward gaze) 378.81 Parkes Weber and Dimitri syndrome (encephalocutaneous angiomatosis) 759.6 Parkinson's disease, syndrome, or tremor [theodora.com]
- Somnolence
Perineum, perineal - see condition Perineuritis NEC 729.2 Periodic - see also condition disease (familial) 277.31 edema 995.1 hereditary 277.6 fever 277.31 limb movement disorder 327.51 paralysis (familial) 359.3 peritonitis 277.31 polyserositis 277.31 somnolence [theodora.com]
Workup
Serum
- Howell-Jolly Bodies
However, the finding of Howell-Jolly bodies, pitted erythrocytes, and target cells in the blood smear is of greater diagnostic significance. [medtextfree.wordpress.com]
========================================================= Howell-Jolly bodies General - Splenosis Reviewer: Jaleh Mansouri, M.D. [pathologyoutlines.com]
Physicians need to know of the spectrum of diseases associated with hyposplenism and how pat ients noted to have Howell-Jolly bodies should be investi gated. [ziladoc.com]
Microbiology
- Staphylococcus Aureus
Aspiration pneumonia* (mixture of bacteria including gram negatives, anaerobes and Staphylococcus aureus). [slideplayer.com]
aureus or Pseudomonas aeruginosa ; in tropics, due to schistosomiasis, microfilariae, various fungi Case reports ========================================================================= 61 year old woman with CLL for 10 years with Nocardia asteroides [pathologyoutlines.com]
- Capnocytophaga
Other implicated or ganisms include Capnocytophaga canimorsus (formerly called DF-2), which can cause a fulminant sepsis following dog bites [9 ]. [ziladoc.com]
Treatment
is 5%-10% If suspected, antibiotic treatment should be initiated without waiting for confirmatory culture testing ** Important note: Pneumococcus can have a very similar presentation to Meningococcemia One of the most contagious infectious diseases, [brainscape.com]
Culture follow-up Urine cultures • Patients with a positive urine culture require treatment tailored to the identified organism and their clinical status. [documents.mx]
Sardjito Yogyakarta 2014 Venous and arterial thrombosis More information Sepsis: Identification and Treatment Sepsis: Identification and Treatment Daniel Z. [docplayer.net]
There is currently no proof that such early self-treatment will lower the incidence of OPSI [1 ]. [ziladoc.com]
This reference stands as a convenient and time-saving reference for clinicians on the diagnosis, treatment, a ما يقوله الناس - كتابة مراجعة لم نعثر على أي مراجعات في الأماكن المعتادة. [books.google.com]
Prognosis
Alveolar hemorrhage incryoglobulinemia e an indicator of poor prognosis. Clin ExpRheumatol 2005;23:616e20.5. Manganelli P, Fietta P, Carotti M, Pesci A, Salaffi F. Respiratorysystem involvement in systemic vasculitides. [docslide.us]
The purpose of this study is to correlate the incidence of bacteremia and the death rate with the more common factors known or supposed to influence the prognosis, including (1) the type of pneumococcus, (2) the age of the patient, (3) the sex, (4) the [scinapse.io]
(See "Acute management, imaging, and prognosis of urinary tract infections in infants and children older than one month", section on 'Overview'.) [documents.mx]
ERSLEV Hypersplenism History and Definition Etiology and Pathogenesis Clinical Features Laboratory Features Therapy, Course, and Prognosis Hyposplenism Definition Etiology and Pathogenesis Clinical Features Laboratory Features Therapy, Course, and Prognosis [medtextfree.wordpress.com]
[…] hairline and coalesces into patches and plaques that spread cephalocaudally to the trunk and extremities --- this lasts for a week before fading to hyperpigmented patches which desquamate Treatment: - Vitamin A deficiency has been associated with a worse prognosis [brainscape.com]
Etiology
The vast majority of young children with fever have an infectious etiology. [documents.mx]
Under the best of circumstances the diagnosis may be easily made, although the exact etiology may be difficult to prove. [scinapse.io]
The striking predilection for the peripapillary retina suggests a local etiologic factor and distinguishes AIBSE from the multiple evanescent white dot syndrome. [ncbi.nlm.nih.gov]
They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]
Mc Coig Etiology and treatment of community-acquired pneumonia in ambulatory children. Pediatr Infect Dis J, 18 (1999), pp. 98-104 [45.] T. Heiskanen-Kosma, M. Korppi, C. Jokinen, S. Kurki, L. Heiskanen, H. [analesdepediatria.org]
Epidemiology
Greater knowledge of the epidemiology of pneumococcal disease and the efficiency of this vaccine in Spain will determine whether it should be included in the immunization schedule. [analesdepediatria.org]
"Blood Pressure" [SH] (epidemiology AND humans) [SH] SI Secondary Source ID The SI field identifies secondary source databanks and accession numbers, e.g., GenBank, GEO, PubChem, ClinicalTrials.gov, ISRCTN. [biomedsearch.com]
Outline Lymphatic System Defense Systems Innate Immune System Adaptive Defense System Immunodeficiencies Immune Responses Lymphatic System: Overview Figure 21.1a, b Lymphatic More information Infective Endocarditis: Infective Endocarditis: definition and epidemiology [docplayer.net]
Patterns of illness in the highly febrile young child: epidemiologic, clinical, and laboratory correlates. Pediatrics 1981; 67:694. 13. Leventhal JM. Clinical predictors of pneumonia as a guide to ordering chest roentgenograms. [documents.mx]
[…] tissue Discontinuous: no connection between spleen and ectopic splenic mass 20% of continuous types associated with other congenital defects, including peromelus (fetus with malformed limbs) and micrognathia; also testicular ectopia, inguinal hernia Epidemiology [pathologyoutlines.com]
Pathophysiology
Pochedly C, Sills RH, Schwartz A (eds): Disorders of the Spleen: Pathophysiology and Management. Marcel Dekker, New York, 1989. 27. [medtextfree.wordpress.com]
Data Extraction: The Extraction: The literature was reviewed to s ummarize the etiology and pathophysiology of postsplenectomy sepsis. [ziladoc.com]
Advertisement General ========================================================================= Largest lymphoid tissue of human body, accounting for 25% of total lymphocytes Lies between fundus of stomach and diaphragm Normally 150g with thin capsule Pathophysiology [pathologyoutlines.com]
Prevention
Alcohol is the third leading cause of preventable mortality and is associated with an estimated 100,000 deaths per year. The annual economic cost of alcohol use in 1990 was $100 billion in the United States, and greater tha... more [scinapse.io]
It has proven efficacy in the prevention of invasive disease caused by the seven vaccine serotypes. In addition, it significantly decreases pneumonia and also prevent acute otitis media. [analesdepediatria.org]
PREVENTIVE STRATEGIES Preventive strategies fall into three major categories: education, immunoprophylaxis, and chemoprophylaxis [5 ] [7] [8 ] ( Table 3 ). Education. Patient education represents a mandatory strategy in attempting t o prevent OPSI. [ziladoc.com]
It would have been hard to foresee, from the guinea-pig experiments, how little antitoxin is necessary in order effectively to prevent the natural infection with diphtheria in human beings. [jimmunol.org]
However, some experts consider two doses of PCV7 or PCV13 sufficient to prevent invasive Streptococcus pneumoniae infection. [documents.mx]