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Shigella Boydii
Shigella Boydii Ewing 1949

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WIKIDATA, Public Domain

Presentation

[…] is known to be present in this location or region. [eol.org]

A rare case of neonatal shigellosis caused by Shigella boydii in a preterm neonate, severe enough to necessitate intensive care support, is presented. [ncbi.nlm.nih.gov]

A cholera-like presentation may occur if the disease is due to S. dysenteriae, which produces a cytotoxin, Shiga toxin. The shiga-like toxins are related, but less potent, and are produced by Shigella sp. and also by enterohaemorrhagic E. Coli. [gpnotebook.com]

Appropriate treatment kills the bacteria present in the gastrointestinal tract and shortens the course of the illness. [textbookofbacteriology.net]

Entire Body System

  • Pain

    In man, shigellosis begins with symptoms of acute gastro-enteritis which is accompanied by abdominal pain and diarrhea. As it progresses, diarrhea becomes more frequent and is usually accompanied colicky pain. [sites.google.com]

    About 2 percent of people with Shigella flexneri develop “post-infectious arthritis”, with symptoms including joint pain, eye irritation, and painful urination. [verywell.com]

    Occasionally, complications may develop, including bacteremia (bacteria in the blood), hemolytic uremic syndrome (a disorder characterized by kidney failure and anemia), and Reiter syndrome (painful urination, joint achiness). [healthychildren.org]

    Symptoms S. sonnei: Most common symptoms are diarrhoea (which is sometimes bloody), abdominal pain and cramps, and fever. Nausea and/or vomiting, loss of appetite, headache or malaise can also occur. [ecdc.europa.eu]

    […] days (usually 1-3 days) but up to 1 week for S. dysenteriae Common clinical features: clinical features vary depending on Shigella species S. sonnei causes mild illness in most cases with symptoms of diarrhoea (may be bloody in 10-50%) and abdominal pain [gpnotebook.com]

  • Inflammation

    Inflammation and ulceration of the lower part of the bowel occurs in most cases, displaying itself as bloody stools. [ecdc.europa.eu]

    The organisms invade the superficial colonic mucosa causing inflammation. Local multiplication and invasion is possible via a virulence factor, together with the production of a toxin. [gpnotebook.com]

    Proctitis and Rectal Prolapse : The bacteria that causes shingellosis can also cause inflammation of the lining of the rectum or rectal prolapse. [foodborneillness.com]

    Apoptotic destruction of macrophages in subepithelial tissue allows survival of the invading shigellae, and inflammation facilitates further bacterial entry. [emedicine.medscape.com]

  • Sepsis

    A preliminary diagnosis of late onset sepsis or necrotizing enterocolitis was made, and appropriate cultures and investigations were undertaken. [journals.lww.com]

    Complications of S. dysenteriae can include an enlarged colon due to toxins, haemolytic uraemic syndrome (HUS)—which is a type of kidney failure, blood clots and sepsis (invasion of the body by toxins). [ecdc.europa.eu]

    Fatal Shigella sepsis in a neutropenic patient. Mt. Sinai J Med 1994;61:367-8. [PubMed] 45 .Khan WA, Seas C, Dhar U, Salam MA, Bennish ML. [antimicrobe.org]

Respiratoric

  • Pneumonia

    NOS group C A03.2 boydii A03.2 Shigellosis A03.9 ICD-10-CM Diagnosis Code A03.9 Shigellosis, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Bacillary dysentery NOS Group C A03.2 ICD-10-CM Codes Adjacent To A03.2 A02.22 Salmonella pneumonia [icd10data.com]

    Pai H, Choi E, Lee H, Yun J, Jacoby GA (2001) Identification of CTX-M-14 Extended-Spectrum β -Lactamase in Clinical Isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea. [journals.plos.org]

    Additionally, Sd197 and Ss046 have ORFs SDY2556 and SSO2450, respectively, which encode proteins similar to the sucrose permease from EHEC (NP_288931) sharing a conserved LacY domain and overall 34% identity with the lactose permease from Klebsiella pneumoniae [dx.doi.org]

Gastrointestinal

  • Diarrhea

    Synonym(s): Flexner bacillus; paradysentery bacillus Shigella sonnei - a species causing mild dysentery and also summer diarrhea in children. [medical-dictionary.thefreedictionary.com]

    […] width = 240px image caption = S. boydii on Hektoen enteric agar. regnum = Bacteria phylum = Proteobacteria classis = Gamma Proteobacteria ordo = Enterobacteriales familia = Enterobacteriaceae … Wikipedia Shigella boydii — a species that causes acute diarrhea [dic.academic.ru]

    In man, shigellosis begins with symptoms of acute gastro-enteritis which is accompanied by abdominal pain and diarrhea. As it progresses, diarrhea becomes more frequent and is usually accompanied colicky pain. [sites.google.com]

  • Abdominal Pain

    In man, shigellosis begins with symptoms of acute gastro-enteritis which is accompanied by abdominal pain and diarrhea. As it progresses, diarrhea becomes more frequent and is usually accompanied colicky pain. [sites.google.com]

    Symptoms S. sonnei: Most common symptoms are diarrhoea (which is sometimes bloody), abdominal pain and cramps, and fever. Nausea and/or vomiting, loss of appetite, headache or malaise can also occur. [ecdc.europa.eu]

    pain with/without nausea, vomiting, headache and malaise lasting average of 4-5 days (range 1 day – 2 weeks) S. flexneri causes similar symptoms to S. sonnei but illness may be more severe with dysentery more prominent, longer duration of illness and [gpnotebook.com]

    Critical Essential Core Tested Community Questions (3) (M1.MC.42) A 14-year-old boy presents with abdominal pain and diarrhea after returning from an East Asian vacation. Stool sample reveals the presence of red and white blood cells. [medbullets.com]

    Common symptoms of bacillary dysentery include acute bloody diarrhea, abdominal pains and cramps, fever, vomiting, dehydration, and tenesmus. [en.citizendium.org]

  • Nausea

    Symptoms include an acute onset of diarrhea, fever, nausea, vomiting, and abdominal cramps. The infectious dose is very low (as few as 10 organisms) and the bacteria are spread by the fecal-oral route. [meridianbioscience.com]

    […] days) but up to 1 week for S. dysenteriae Common clinical features: clinical features vary depending on Shigella species S. sonnei causes mild illness in most cases with symptoms of diarrhoea (may be bloody in 10-50%) and abdominal pain with/without nausea [gpnotebook.com]

    Shigella infections can cause stomach cramps, nausea and diarrhoea, and worryingly it is also increasingly resistant to antibiotics. Read on for five more Shigella facts that you may not know… 1. [biocote.com]

    Nausea and/or vomiting, loss of appetite, headache or malaise can also occur. S. flexneri: Also causes diarrhoea, abdominal pain and cramps, and fever but is often more severe than S. sonnei infection. [ecdc.europa.eu]

    There is also fever and nausea that accompany the diarrhea. Some people however also suffer from vomiting and cramping, and some show no symptoms at all. [web.uconn.edu]

  • Blood in Stool

    Stool sample reveals the presence of red and white blood cells. Stool culture shows growth of immobile, non-lactose fermenting gram-negative rods. [medbullets.com]

    A stool examination revealed occult blood, and an abdominal roentgenogram showed bowel wall edema with colonic dilatation, without intramural gas. The following day, the neonate passed several slimy stools with blood. [journals.lww.com]

    Various tests, such as blood films, stool microscopy, stool culture and cerebrospinal fluid cultures, were conducted to determine the cause of this case of Shigellosis, but all came up negative. [en.citizendium.org]

  • Intestinal Disease

    Shigellosis cannot be diagnosed by its symptoms alone, because diarrhea is a common symptom of many intestinal diseases. [safewater.org]

    Infection - Shigella primarily affects the large intestine while Salmonella affects both the small and large intestine. [microscopemaster.com]

Musculoskeletal

  • Arthritis

    (Reiter syndrome) classic triad of conjunctivitis, urethritis, and arthritis Febrile seizures Please rate topic. [medbullets.com]

    Reactive Arthritis : Approximately 3 percent of patients with Shigella infection, most often those with Shigella flexneri, develop Reactive Arthritis. It occurs when the immune system attempts to combat Shigella but instead attacks the body. [foodborneillness.com]

    […] lasting average of 4-5 days (range 1 day – 2 weeks) S. flexneri causes similar symptoms to S. sonnei but illness may be more severe with dysentery more prominent, longer duration of illness and hospitalisation rates higher complications include reactive arthritis [gpnotebook.com]

    Shigellosis A03.9 ICD-10-CM Diagnosis Code A03.9 Shigellosis, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Bacillary dysentery NOS Group C A03.2 ICD-10-CM Codes Adjacent To A03.2 A02.22 Salmonella pneumonia A02.23 Salmonella arthritis [icd10data.com]

    This is called post-infectious arthritis. It can last for months or years, and can lead to chronic arthritis. Post-infectious arthritis is caused by a reaction to Shigella infection that happens only in people who are genetically predisposed to it. [medicinenet.com]

Neurologic

  • Irritability

    This penetration causes severe irritation which is responsible for the cramps and watery, bloody diarrhea. Dehydration can become a complication. VIRULENCE FACTORS: Virulence genes of this organism are coded on both chromosomes and plasmids. [web.uconn.edu]

    About 2 percent of people with Shigella flexneri develop “post-infectious arthritis”, with symptoms including joint pain, eye irritation, and painful urination. [verywell.com]

    About 3% of persons who are infected with Shigella flexneri may subsequently develop pains in their joints, irritation of the eyes, and painful urination. This condition is called Reiter's syndrome. [textbookofbacteriology.net]

    Once ingested, the Shigella makes its way through the gastrointestinal tract until it reaches the epithelial cells of the intestinal mucosa, there it infects, causing irritation, inflammation and necrosis (swelling and breaking of infected cells, which [microbewiki.kenyon.edu]

  • Meningism

    10-CM Diagnosis Code A03.9 Shigellosis, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Bacillary dysentery NOS Group A A03.0 ICD-10-CM Codes Adjacent To A03.0 A02.20 Localized salmonella infection, unspecified A02.21 Salmonella meningitis [icd10data.com]

    Thus their combined action leads to severe diarrhea, polyneuritis, coma, and meningitis. [universe84a.com]

Workup

Colonoscopy

  • Colitis

    unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Infectious colitis NOS Infectious enteritis NOS Infectious gastroenteritis NOS Type 1 Excludes colitis NOS ( K52.9 ) diarrhea NOS ( R19.7 ) enteritis NOS ( K52.9 ) gastroenteritis [icd10data.com]

    Abstract Enterohemorrhagic Escherichia coli (EHEC) is a foodborne pathogen that causes watery diarrhea and hemorrhagic colitis. [ncbi.nlm.nih.gov]

    Infections with Shiga toxin-producing bacteria are known to cause bloody diarrhea (hemorrhagic colitis). [certest.es]

Treatment

Emergence of antimicrobial resistance threatens to render current treatments ineffective. [hal.archives-ouvertes.fr]

II (revived; treatment); likewise, ATCC B was labeled as Gr. III (lyophilized; treatment). 2.2. Biofield Treatment Strategy The Gr. I remained as untreated. The treatment Gr. II and III in sealed pack were handed over to Mr. [trivedieffect.com]

Recommendations for the Public Health Management of Gastrointestinal Infections clinical features complications diagnosis treatment of shigellosis treatment in HIV infected individuals shigellosis (Shigella) - exclusion from work and school advice [gpnotebook.com]

Because of the frequent resistance to other antimicrobial agents and the relatively short treatment course, quinolone treatment in children may be useful. [antimicrobe.org]

The treatment of bacillary dysentery Read More [britannica.com]

Prognosis

PROGNOSIS AND PREVENTION: Prognosis for those infected is good. This organism can be successfully treated with antibiotics such as ampicillin and ciprofloxacin (in severe cases). Fluids can be given to those individuals suffering from dehydration. [web.uconn.edu]

What Is the Prognosis? In most cases, Shigella infections run their course in 2 to 3 days. [healthychildren.org]

[…] toxin (enterotoxin) "A" subunit inactivates 60S ribosome kills intestinal cells by inhibiting protein synthesis neurotoxic, cytotoxic, and enterotoxic produced by S. dysenteriae Associated conditions shigellosis (bacillary dysentery) reactive arthritis Prognosis [medbullets.com]

Prognosis Usually goes away within 5 to 7 days; hospitalization is rare. Treatment Usually not necessary, but antibiotics can shorten the illness. [verywell.com]

The prognosis for shigellosis is generally good and most people recover even without medications within five to seven days. What is shigellosis? Shigellosis is a diarrheal disease caused by a group of bacteria called Shigella. [medicinenet.com]

Etiology

Publications "Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." [uniprot.org]

Title Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Journal Nucleic Acids Res 33:6445-58 (2005) DOI: 10.1093/nar/gki954 [genome.jp]

Shigella was recognized as the etiologic agent for bacillary dysentery in the 1890's, and adopted as a genus in the 1950's and subgrouped into four species. [bacmap.wishartlab.com]

Epidemiology

However, this cannot be substantiated by epidemiological data because a detailed epidemiological investigation was not conducted. CONCLUSIONS: We have documented the first cluster of S. boydii infection in SA. [ncbi.nlm.nih.gov]

However, this cannot be substantiated by epidemiological data because a detailed epidemiological investigation was not conducted. Conclusions: We have documented the first cluster of S. boydii infection in SA. [jidc.org]

The results obtained from present study could be helpful for a future epidemiological surveillance of Shigella in this country. [bmcresnotes.biomedcentral.com]

Prevention

The roles of breast-feeding, hand-washing and surveillance for enteric infections in the prevention of shigellosis in low risk settings such as a special care baby unit are highlighted. [ncbi.nlm.nih.gov]

It is generally believed that a vaccine comprising S. sonnei, S. dysenteriae type 1, S. flexneri 2a, S. flexneri 3, and S. flexneri 6 antigens can prevent 75% of Shigella-induced diarrhea worldwide. [creative-biolabs.com]

How do I Prevent Spreading it to Others? You can prevent spreading shigellosis to others by following the same guidelines that are given to prevent getting shigellosis. [safewater.org]

Shigellosis, a diarrheal disease caused by bacteria, is one of several infections that can be easily prevented with good hygiene and frequent hand washing. [verywell.com]

Proper food handling is also an important method of prevention, as well as maintaining clean water supplies, which is highly effective. [web.uconn.edu]

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