Average 5.0 of 6 Ratings Questions (4) Previous Next Sorry, this question is for PEAK Premium Subscribers only Sorry, this question is for PEAK Premium Subscribers only (M1.MC.12.42) A 14-year-old boy presents with abdominal pain and diarrhea after returning [step1.medbullets.com]

It is a particularly infectious and virulent form of dysentery which can cause clinical confusion with other endemic diseases and may present to the surgeon as a result of its complications. [ncbi.nlm.nih.gov]

The muscle tissue (m) present skeletal muscle fibers with compact aspect and multinucleate cells (Fig. 1c). [scielo.cl]

• Diarrhea

  Topic Snapshot A 6-year-old girl is brought in to the emergency department for a 2-day history of fever and watery diarrhea. This morning, the diarrhea contained some blood. She had just traveled to Bangladesh to visit relatives. [step1.medbullets.com]

  Six strains belonging to provisional serovars of S. dysenteriae were also identified for the first time in patients hospitalized with diarrhea in Kolkata, India. [ncbi.nlm.nih.gov]

  Snapshot A 6-year-old girl is brought in to the emergency department for a 2-day history of fever and watery diarrhea. This morning, the diarrhea contained some blood. She had just traveled to Bangladesh to visit relatives. [medbullets.com]

• Abdominal Pain

  pain or cramping Physical exam fever hyperactive bowel sounds abdominal tenderness signs of dehydration Studies Labs stool culture Making the diagnosis based on clinical presentation and laboratory studies Differential Enteroinvasive Escherichia coli [step1.medbullets.com]

  Critical Essential Core Tested Community Questions (3) (M1.MC.42) A 14-year-old boy presents with abdominal pain and diarrhea after returning from an East Asian vacation. Stool sample reveals the presence of red and white blood cells. [medbullets.com]

  Shigellosis is a worldwide disease, characterized by abdominal pain, fever, vomiting, and the passage of blood- and mucus-streaked stools. Rhesus monkeys and other primates are the only animals that are naturally susceptible to shigellosis. [ncbi.nlm.nih.gov]

• Nausea

  The mean incubation period until onset of diarrhea was 25 hours and was preceded by nausea, abdominal discomfort, and bloating. Patients were treated with ciprofloxacin. No deaths occurred among the ill workers. [ojp.gov]

  Nausea, vomiting, myalgias, and dehydration were frequently noted. [cdc.gov]

  There is also fever and nausea that accompany the diarrhea. Some people however also suffer from vomiting and cramping, and some show no symptoms at all. [web.uconn.edu]

  Shigella infections can cause stomach cramps, nausea and diarrhoea, and worryingly it is also increasingly resistant to antibiotics. Read on for five more Shigella facts that you may not know… 1. [biocote.com]

• Blood in Stool

  Stool sample reveals the presence of red and white blood cells. Stool culture shows growth of immobile, non-lactose fermenting gram-negative rods. [step1.medbullets.com]

  Stool microscopy for pus cells to identify shigellosis is not necessary when visible blood is present in stools. [rehydrate.org]

• Hyperactive Bowel Sounds

  On physical exam, she is febrile, has hyperactive bowel sounds, and abdominal tenderness to palpation. A stool culture and Gram stain reveals lactose-fermenting, gram - rods. She is admitted for immediate rehydration and treatment. [step1.medbullets.com]

• Febrile Seizures

  seizures Please rate topic. [step1.medbullets.com]

• Meningism

  About Conjugate Vaccines Conjugate vaccines are largely used to prevent important invasive bacterial diseases such as bacteraemia (bloodstream infection), pneumonia, and meningitis, with the market leader achieving nearly USD3 billion in annual sales [businesswire.com]

  Meninges — Outer covering of the spinal cord and brain. Infection is called meningitis, which can lead to damage to the brain or spinal cord and lead to death. [medical-dictionary.thefreedictionary.com]

  10-CM Diagnosis Code A03.9 Shigellosis, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Bacillary dysentery NOS Group A A03.0 ICD-10-CM Codes Adjacent To A03.0 A02.20 Localized salmonella infection, unspecified A02.21 Salmonella meningitis [icd10data.com]

• Calcium Increased

  On the other hand, changes in cell junction include increases of intracellular calcium. Calcium increase results in a decrease of cell-cell communications and could result in detachment of desmosomes, intermediate junctions and tight junctions. [scielo.cl]

• Colitis

  unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Infectious colitis NOS Infectious enteritis NOS Infectious gastroenteritis NOS Type 1 Excludes colitis NOS ( K52.9 ) diarrhea NOS ( R19.7 ) enteritis NOS ( K52.9 ) gastroenteritis [icd10data.com]

  The illness resembled fulminant ulcerative colitis and its infectious nature was difficult to establish because several fecal cultures failed to grow the pathogen. [ncbi.nlm.nih.gov]

Mannitol tests yields negative results.[6] Ornithine Decarboxylase tests yield negative results.[6] Treatment[edit] Treatment for shigellosis, independent of the subspecies, requires an antibiotic. [en.wikipedia.org]

Treatment failure with ciprofloxacin occurred in six patients who received cefotaxime and amikacin. There were 38 children below 5 yr of age. [ncbi.nlm.nih.gov]

She is admitted for immediate rehydration and treatment. [step1.medbullets.com]

Shigella infections treatment Should be always guided by in vitro susceptibility tests!! Persons with mild infections usually recover quickly without antibiotic treatment. [bacteria.cz]

[…] toxin (enterotoxin) "A" subunit inactivates 60S ribosome kills intestinal cells by inhibiting protein synthesis neurotoxic, cytotoxic, and enterotoxic produced by S. dysenteriae Associated conditions shigellosis (bacillary dysentery) reactive arthritis Prognosis [step1.medbullets.com]

PROGNOSIS AND PREVENTION: Prognosis for those infected is good. This organism can be successfully treated with antibiotics such as ampicillin and ciprofloxacin (in severe cases). Fluids can be given to those individuals suffering from dehydration. [web.uconn.edu]

Abstract Summary Shigella Group A, Type 1 ( S. dysenteriae ), was isolated from 18 (35%) of 51 patients with severe dysentery and was considered the etiological agent in those cases. [ajtmh.org]

Title Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Journal Nucleic Acids Res 33:6445-58 (2005) DOI: 10.1093/nar/gki954 [genome.jp]

Publications "Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery." [uniprot.org]

BACKGROUND: Shigella is the etiological agent of shigellosis, a disease responsible for more than 500,000 deaths of children per year, in developing countries. [ncbi.nlm.nih.gov]

Thermo Scientific™ Shigella dysenteriae Polyvalent (1-10) Agglutinating Sera Catalog number: R30163701 Presumptively identify Shigella cultures for epidemiological and diagnostic purposes using Thermo Scientific™ Remel™ Shigella dysenteriae Polyvalent [thermofisher.com]

Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 48 (‎25)‎, 254 - 255. https://apps.who.int/iris/handle/10665/219422 Журнал Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 48 (‎25)‎: 254 - 255 [apps.who.int]

Publication type, MeSH terms Publication type Historical Article MeSH terms Drug Resistance, Bacterial Dysentery, Bacillary/epidemiology* Dysentery, Bacillary/history Dysentery, Bacillary/microbiology* Evolution, Molecular* Genome, Bacterial Global Health [ncbi.nlm.nih.gov]

[…] shigella epidemiology in adults in London from 2011 to 2015. 1 December 2013 First published. [gov.uk]

Sites Disease occurs primarily in the left colon and involvement of the terminal ileum is common Disease may occur in other parts of the large bowel Very rarely, fulminant disease occurs because of massive small intestinal invasion (Ikari syndrome) Pathophysiology [pathologyoutlines.com]

References Pathophysiology of gastrointestinal infections: the role of bismuth subsalicylate. Scottsdale, Arizona, 11-14 February 1988. Proceedings. Rev Infect Dis. 1990;12 Suppl 1:S1-119. Steffen R. [cdc.gov]

Amongst milk compounds, glycosylated proteins prevent the adhesion of many enteropathogens in vitro. [ncbi.nlm.nih.gov]

Proper food handling is also an important method of prevention, as well as maintaining clean water supplies, which is highly effective. [web.uconn.edu]

The study in forty healthy volunteers assessed the safety, tolerability and antibody response to the bioconjugate vaccine and was conducted at the Institute for Social and Preventive Medicine of the University of Zürich, Switzerland, under the supervision [businesswire.com]