Addition features include variable degrees of intellectual deficit, microcephaly and dysmorphism (broad nasal bridge and tip, smooth philtrum, thin upper and everted lower lips, short fingers, clinodactyly, wide-set nipples and pectus excavatum). [orpha.net]

Insulin-like growth factor I production is inhibited in human sepsis. Arch Surg. 1988; 123:1409-14. Maes M, Underwood LE, Ketelslegers JM. [annals.org]

All patients were able to tolerate the maximum dosage of liraglutide (1.8 mg once daily), except one patient who continued with a dose of 1.2 mg/day because of persistent nausea. [doi.org]

In the last 2 to 3 weeks, however, adverse effects appeared, including arthralgia in his hips and knees, generalized myalgia, exhaustion, lower back pain, and chills for up to 30 minutes several times each day. [annals.org]

Four of the 48 patients receiving the higher dose experienced effects consistent with GH excess, such as enlarging shoe size, ankle swelling, and hip pain. [karger.com]

impairment 0008619 Congenital sensorineural hearing impairment 0008527 Failure to thrive Faltering weight Weight faltering [ more ] 0001508 Insulin resistance Body fails to respond to insulin 0000855 Intellectual disability, mild Mental retardation, [rarediseases.info.nih.gov]

In all cases, after obtaining an informed written consent from the subjects' parents, 5 ml of venous blood was withdrawn for measurement of IGF-1 and serum ferritin. [thefreelibrary.com]

Showing of 45 80%-99% of people have these symptoms Abnormal facial shape Unusual facial appearance 0001999 Attention deficit hyperactivity disorder Attention deficit Attention deficit disorder Attention deficit-hyperactivity disorder Attention deficits [rarediseases.info.nih.gov]

It occurs at an overall incidence of 28 per 100,000 treatment-years, with a higher rate among patients with chronic renal insufficiency, Turner syndrome, and organic GHD, and at a lower rate in patients with ISS. [karger.com]

Daily fasting and preprandial glucose measurements continued to range from 11.1 to 27.8 mmol/L and polyuria, glycosuria, and ketonuria persisted. [annals.org]